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Douglas B. Evans
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Journal Articles

Abstract CT080: A phase I study of CPI-613 (devimistat) in combination with chemoradiation in patients with pancreatic ductal adenocarcinoma

Mandana Kamgar, Husain Yar Khan, Amro Aboukameel, Sahar F. Bannoura, Brian Y. Chung, Aniko Szabo, Yiwei Li, Mohammed Najeeb Al Hallak, Philip A. Philip, Ben George, Kathleen K. Christians, Douglas B. Evans, Susan Tsai, Beth Erickson, John M. Goldberg, Asfar S. Azmi, William A. Hall
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT080.
https://doi.org/10.1158/1538-7445.AM2024-CT080
Published: 05 April 2024
View articletitled, Abstract CT080: A phase I study of CPI-613 (devimistat) in combination with chemoradiation in patients with pancreatic ductal adenocarcinoma
Journal Articles

Abstract PO-024: Targeting cellular metabolism with CPI-613 sensitizes pancreatic cancer cells to radiotherapy

William A. Hall, Husain Y. Khan, Mandana Kamgar, Susan Tsai, Kathleen Christians, Douglas B. Evans, Philip Philip, Callisia Clarke, Ben George, Beth Erickson, Asfar S. Azmi
Journal: Cancer Research
Cancer Res (2021) 81 (22_Supplement): PO-024.
https://doi.org/10.1158/1538-7445.PANCA21-PO-024
Published: 15 November 2021
View articletitled, Abstract PO-024: Targeting cellular metabolism with CPI-613 sensitizes pancreatic cancer cells to radiotherapy
Journal Articles

Abstract PO-055: Phase II clinical trial of subtype directed neoadjuvant therapy in patients with localized pancreatic cancer

Susan Tsai, Erkut Borazanci, Margaret Gulley, Naim Rashid, Jason Merker, Abdul H. Khan, Phillip Chisholm, Bryan Hunt, Tamara Giorgadze, William Hall, Mandana Kamgar, Douglas B. Evans, Jen Jen Yeh
Journal: Cancer Research
Cancer Res (2021) 81 (22_Supplement): PO-055.
https://doi.org/10.1158/1538-7445.PANCA21-PO-055
Published: 15 November 2021
View articletitled, Abstract PO-055: Phase II clinical trial of subtype directed neoadjuvant therapy in patients with localized pancreatic cancer
Journal Articles

Abstract 762: A non-invasive miRNA signature for the identification of pancreatic ductal adenocarcinoma (PDAC) patients with poor molecular subtypes and worse prognosis

Raju Kandimalla, Tadanobu Shimura, Saurav Mallik, Susan Tsai, Douglas B. Evans, Hideo Baba, Yasuhiro Kodera, Xi Chen, Ajay Goel
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 762.
https://doi.org/10.1158/1538-7445.AM2019-762
Published: 01 July 2019
View articletitled, Abstract 762: A non-invasive miRNA signature for the identification of pancreatic ductal adenocarcinoma (PDAC) patients with poor molecular subtypes and worse prognosis
Journal Articles

Abstract 2581: Identification and establishment of a novel, circulating miRNA signature, for pre-operative diagnosis of occult distant metastasis in patients with pancreatic ductal adenocarcinoma

Kensuke Yamamura, Susan Tsai, Jasjit K. Banwait, Fuminori Sonohara, Douglas B. Evans, Yasuhiro Kodera, Hideo Baba, Ajay Goel
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2581.
https://doi.org/10.1158/1538-7445.AM2019-2581
Published: 01 July 2019
View articletitled, Abstract 2581: Identification and establishment of a novel, circulating miRNA signature, for pre-operative diagnosis of occult distant metastasis in patients with pancreatic ductal adenocarcinoma
Journal Articles

Abstract A21: Chemokine directed migration of activated stellate cells in pancreatic ductal adenocarcinoma

Ishan Roy, Kathleen A. Boyle, A Craig Mackinnon, Rosa F. Hwang, Susan Tsai, Douglas B. Evans, Michael B. Dwinell
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): A21.
https://doi.org/10.1158/1538-7445.PANCA16-A21
Published: 14 December 2016
View articletitled, Abstract A21: Chemokine directed migration of activated stellate cells in pancreatic ductal adenocarcinoma
Journal Articles

Pancreatic Cancer Cell Migration and Metastasis Is Regulated by Chemokine-Biased Agonism and Bioenergetic Signaling

Ishan Roy, Donna M. McAllister, Egal Gorse, Kate Dixon, Clinton T. Piper, Noah P. Zimmerman, Anthony E. Getschman, Susan Tsai, Dannielle D. Engle, Douglas B. Evans, Brian F. Volkman, Balaraman Kalyanaraman, Michael B. Dwinell
Journal: Cancer Research
Cancer Res (2015) 75 (17): 3529–3542.
https://doi.org/10.1158/0008-5472.CAN-14-2645
Published: 31 August 2015
View articletitled, Pancreatic Cancer Cell Migration and Metastasis Is Regulated by Chemokine-Biased Agonism and Bioenergetic Signaling
Open the PDF for Pancreatic Cancer Cell Migration and Metastasis Is Regulated by Chemokine-Biased Agonism and Bioenergetic Signaling in another window
Includes: Supplementary data
Journal Articles

Abstract A74: CXCL12 and CXCR4 are reciprocally expressed in normal pancreatic ducts and pancreatic ductal adenocarcinoma respectively.

Ishan Roy, Noah P. Zimmerman, Susan Tsai, Douglas B. Evans, Michael B. Dwinell
Journal: Cancer Research
Cancer Res (2012) 72 (14_Supplement): A74.
https://doi.org/10.1158/1538-7445.PANCA2012-A74
Published: 03 April 2014
View articletitled, Abstract A74: CXCL12 and CXCR4 are reciprocally expressed in normal pancreatic ducts and pancreatic ductal adenocarcinoma respectively.
Journal Articles

TrkBT1 Induces Liver Metastasis of Pancreatic Cancer Cells by Sequestering Rho GDP Dissociation Inhibitor and Promoting RhoA Activation

Zhongkui Li, Zhe Chang, Lucia J. Chiao, Ya'an Kang, Qianghua Xia, Cihui Zhu, Jason B. Fleming, Douglas B. Evans, Paul J. Chiao
Journal: Cancer Research
Cancer Res (2009) 69 (19): 7851–7859.
https://doi.org/10.1158/0008-5472.CAN-08-4002
Published: 01 October 2009
View articletitled, TrkBT1 Induces Liver Metastasis of Pancreatic Cancer Cells by Sequestering Rho GDP Dissociation Inhibitor and Promoting RhoA Activation
Open the PDF for TrkBT1 Induces Liver Metastasis of Pancreatic Cancer Cells by Sequestering Rho GDP Dissociation Inhibitor and Promoting RhoA Activation in another window
Includes: Supplementary data
Journal Articles

Proteasome-Mediated Degradation and Functions of Hematopoietic Progenitor Kinase 1 in Pancreatic Cancer

Hua Wang, Xianzhou Song, Craig Logsdon, Guisheng Zhou, Douglas B. Evans, James L. Abbruzzese, Stanley R. Hamilton, Tse-Hua Tan, Huamin Wang
Journal: Cancer Research
Cancer Res (2009) 69 (3): 1063–1070.
https://doi.org/10.1158/0008-5472.CAN-08-1751
Published: 29 January 2009
View articletitled, Proteasome-Mediated Degradation and Functions of Hematopoietic Progenitor Kinase 1 in Pancreatic Cancer
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Journal Articles

Significant effects of mismatch repair gene polymorphisms on clinical outcome of pancreatic cancer

Xiaoqun Dong, Li Jiao, Yanan Li, Douglas B. Evans, James L. Abbruzzese, Donghui Li
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1900.
Published: 01 May 2008
View articletitled, Significant effects of mismatch repair gene polymorphisms on clinical outcome of pancreatic cancer
Journal Articles

Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression

Rosa F. Hwang, Todd Moore, Thiruvengadam Arumugam, Vijaya Ramachandran, Keith D. Amos, Armando Rivera, Baoan Ji, Douglas B. Evans, Craig D. Logsdon
Journal: Cancer Research
Cancer Res (2008) 68 (3): 918–926.
https://doi.org/10.1158/0008-5472.CAN-07-5714
Published: 01 February 2008
View articletitled, Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression
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Journal Articles

Potential Role of Jun Activation Domain–Binding Protein 1 as a Negative Regulator of p27kip1 in Pancreatic Adenocarcinoma

Maria A. Kouvaraki, Anita L. Korapati, George Z. Rassidakis, Ling Tian, Qingxiu Zhang, Paul Chiao, Linus Ho, Douglas B. Evans, François X. Claret
Journal: Cancer Research
Cancer Res (2006) 66 (17): 8581–8589.
https://doi.org/10.1158/0008-5472.CAN-06-0975
Published: 01 September 2006
View articletitled, Potential Role of Jun Activation Domain–Binding Protein 1 as a Negative Regulator of p27kip1 in Pancreatic Adenocarcinoma
Open the PDF for Potential Role of Jun Activation Domain–Binding Protein 1 as a Negative Regulator of p27kip1 in Pancreatic Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Polymorphisms of RecQ1, RAD54L, ATM and XRCC1 genes and prognosis of pancreatic cancer

Donghui Li, Douglas B. Evans, Kenneth Hess, Marsha Frazier, James L. Abbruzzese
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 287.
Published: 15 April 2006
View articletitled, Polymorphisms of RecQ1, RAD54L, ATM and XRCC1 genes and prognosis of pancreatic cancer
Journal Articles

Interleukin-8 is regulated by a Src/STAT3 pathway in pancreatic adenocarcinoma cells that is NF-κB independent

José G. Trevino, Jr., Michael J. Gray, Justin M. Summy, Steffan T. Nawrocki, Douglas B. Evans, Paul J. Chiao, Stephanie S. Watowich, Gary E. Gallick
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1135.
Published: 15 April 2006
View articletitled, Interleukin-8 is regulated by a Src/STAT3 pathway in pancreatic adenocarcinoma cells that is NF-κB independent
Journal Articles

Significant Effect of Homologous Recombination DNA Repair Gene Polymorphisms on Pancreatic Cancer Survival

Donghui Li, Hui Liu, Li Jiao, David Z. Chang, Garth Beinart, Robert A. Wolff, Douglas B. Evans, Manal M. Hassan, James L. Abbruzzese
Journal: Cancer Research
Cancer Res (2006) 66 (6): 3323–3330.
https://doi.org/10.1158/0008-5472.CAN-05-3032
Published: 15 March 2006
View articletitled, Significant Effect of Homologous Recombination DNA Repair Gene Polymorphisms on Pancreatic Cancer Survival
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Journal Articles

Targeting of Urokinase Plasminogen Activator Receptor in Human Pancreatic Carcinoma Cells Inhibits c-Met– and Insulin-like Growth Factor-I Receptor–Mediated Migration and Invasion and Orthotopic Tumor Growth in Mice

Todd W. Bauer, Wenbiao Liu, Fan Fan, Ernest R. Camp, Anthony Yang, Ray J. Somcio, Corazon D. Bucana, Jennifer Callahan, Graham C. Parry, Douglas B. Evans, Douglas D. Boyd, Andrew P. Mazar, Lee M. Ellis
Journal: Cancer Research
Cancer Res (2005) 65 (17): 7775–7781.
https://doi.org/10.1158/0008-5472.CAN-05-0946
Published: 01 September 2005
View articletitled, Targeting of Urokinase Plasminogen Activator Receptor in Human Pancreatic Carcinoma Cells Inhibits c-Met– and Insulin-like Growth Factor-I Receptor–Mediated Migration and Invasion and Orthotopic Tumor Growth in Mice
Open the PDF for Targeting of Urokinase Plasminogen Activator Receptor in Human Pancreatic Carcinoma Cells Inhibits c-Met– and Insulin-like Growth Factor-I Receptor–Mediated Migration and Invasion and Orthotopic Tumor Growth in Mice in another window
Journal Articles

Neuropilin-1 Suppresses Tumorigenic Properties in a Human Pancreatic Adenocarcinoma Cell Line Lacking Neuropilin-1 Coreceptors

Michael J. Gray, Jane S. Wey, Anna Belcheva, Marya F. McCarty, Jose G. Trevino, Douglas B. Evans, Lee M. Ellis, Gary E. Gallick
Journal: Cancer Research
Cancer Res (2005) 65 (9): 3664–3670.
https://doi.org/10.1158/0008-5472.CAN-04-2229
Published: 02 May 2005
View articletitled, Neuropilin-1 Suppresses Tumorigenic Properties in a Human Pancreatic Adenocarcinoma Cell Line Lacking Neuropilin-1 Coreceptors
Open the PDF for Neuropilin-1 Suppresses Tumorigenic Properties in a Human Pancreatic Adenocarcinoma Cell Line Lacking Neuropilin-1 Coreceptors in another window
Journal Articles

Genotype and hyplotype of XRCC2, XRCC3, and Rad54L genes and risk of pancreatic cancer

Li Jiao, Manal M. Hassan, Douglas B. Evans, James L. Abbruzzese, Donghui Li
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 964–965.
Published: 01 May 2005
View articletitled, Genotype and hyplotype of XRCC2, XRCC3, and Rad54L genes and risk of pancreatic cancer
Journal Articles

DNA repair gene polymorphisms and risk of pancreatic cancer

Donghui Li, Manal M. Hassan, Li Jiao, Marsha Frazier, Douglas B. Evans, James L. Abbruzzese
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 964.
Published: 01 May 2005
View articletitled, DNA repair gene polymorphisms and risk of pancreatic cancer