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Journal Articles

Abstract 668: A MYOD-SKP2 axis boosts oncogenic properties of fusion negative rhabdomyosarcoma and is counteracted by neddylation inhibition in vitro and in vivo

Cancer Res (2022) 82 (12_Supplement): 668.

DOI: https://doi.org/10.1158/1538-7445.AM2022-668

Published: 15 June 2022

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Journal Articles

Abstract 3048: Surfaceome profiling identifies the immune checkpoint molecule B7-H3 as a key player of immune-evasion in rhabdomyosarcoma

Roxane R. Lavoie, Yohan Kim, Mohamed E. Ahmed, Doris Phelps, Emily Baer, Cristine Charlesworth, Benjamin Madden, Liguo Wang, Haidong Dong, Peter Houghton, John Cheville, Patricio Gargollo, Candace Granberg, Fabrice Lucien

Cancer Res (2021) 81 (13_Supplement): 3048.

DOI: https://doi.org/10.1158/1538-7445.AM2021-3048

Published: 01 July 2021

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Journal Articles

Abstract B09: IL6 and CXCL8 mediate redundant tumor-host signaling pathways that facilitate osteosarcoma lung metastasis

Ryan D. Roberts, Hakan Cam, Amy C. Gross, Sarah Winget, Doris Phelps, Peter J. Houghton

Cancer Res (2018) 78 (19_Supplement): B09.

DOI: https://doi.org/10.1158/1538-7445.PEDCA17-B09

Published: 01 October 2018

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Journal Articles

Abstract 4873: Shedding light on the unknown of Ewing sarcoma: Single cell study shows a co-expression pattern between TAPA-1 and EWSR1-FLI1

Roxane Khoogar, Doris Phelps, Peter Houghton

Cancer Res (2017) 77 (13_Supplement): 4873.

DOI: https://doi.org/10.1158/1538-7445.AM2017-4873

Published: 01 July 2017

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Journal Articles

Abstract 5825: Mechanisms of intrinsic and acquired resistance to antibodies targeting IGF-1R in pediatric sarcoma cell lines

Terry J. Shackleford, Seethalakshmi Hariharan, Doris Phelps, Hemant Bid, Hiahong Zhong, Peter Houghton

Cancer Res (2017) 77 (13_Supplement): 5825.

DOI: https://doi.org/10.1158/1538-7445.AM2017-5825

Published: 01 July 2017

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Journal Articles

Abstract B40: Autocrine and paracrine IL-6 and IL-8 drive osteosarcoma lung tropism and facilitate metastasis

Ryan D. Roberts, Amy C. Gross, Hemant K. Bid, Doris Phelps, Mary F. Wedekind, Peter J. Houghton

Cancer Res (2016) 76 (5_Supplement): B40.

DOI: https://doi.org/10.1158/1538-7445.PEDCA15-B40

Published: 04 April 2016

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Journal Articles

Abstract 477: Inhibition of MEK confers hypersensitivity to X-radiation in the context of BRAF mutation in a model of childhood astrocytoma

Adam W. Studebaker, Kathryn Bondra, Star Seum, Justin Leasure, Christopher Chronowski, Changxian Shen, Doris Phelps, Paul D. Smith, Raushan T. Kurmasheva, Xiaokui Mo, Peter J. Houghton

Cancer Res (2015) 75 (15_Supplement): 477.

DOI: https://doi.org/10.1158/1538-7445.AM2015-477

Published: 01 August 2015

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Journal Articles

Abstract A45: Autocrine and paracrine IL-6 and IL-8 drive osteosarcoma metastasis

Ryan D. Roberts, Hemant K. Bid, Doris Phelps, Brett W. Hendrickson, Hakan Cam, Peter J. Houghton

Cancer Res (2014) 74 (20_Supplement): A45.

DOI: https://doi.org/10.1158/1538-7445.PEDCAN-A45

Published: 09 October 2014

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Journal Articles

Regulation of FANCD2 by the mTOR Pathway Contributes to the Resistance of Cancer Cells to DNA Double-Strand Breaks

Changxian Shen, Duane Oswald, Doris Phelps, Hakan Cam, Christopher E. Pelloski, Qishen Pang, Peter J. Houghton

Cancer Res (2013) 73 (11): 3393–3401.

DOI: https://doi.org/10.1158/0008-5472.CAN-12-4282

Published: 30 May 2013

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Includes: Supplementary data

Journal Articles

Abstract 4437: Regulation of FANCD2 by the mTOR pathway contributes to the resistance of cancer cells to DNA double strand breaks.

Changxian Shen, Duane Oswald, Doris Phelps, hakan cam, Christopher E. Pelloski, Qishen Pang, Peter J. Houghton

Cancer Res (2013) 73 (8_Supplement): 4437.

DOI: https://doi.org/10.1158/1538-7445.AM2013-4437

Published: 15 April 2013

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Journal Articles

Abstract 3277: Insulin-like growth factor-2 (IGF-2) circumvents the antiangiogenic activity of SCH717454, a human antibody that blocks ligand binding to the Type 1 insulin-like growth factor receptor (IGF-1R)

Hemant K. Bid, Doris Phelps, Peter J. Houghton

Cancer Res (2011) 71 (8_Supplement): 3277.

DOI: https://doi.org/10.1158/1538-7445.AM2011-3277

Published: 15 April 2011

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Journal Articles

Molecular characterization of the Pediatric Preclinical Testing Program (PPTP) models

Geoffrey Neale, Xiaoping Su, Christopher Morton, Doris Phelps, Richard Gorlick, Richard Lock, C. Reynolds, John Maris, Henry Friedman, Jeffrey Dome, Joseph Khoury, Timothy Triche, Robert Seeger, Richard Gilbertson, Javed Khan, Malcolm Smith, Peter Houghton

Cancer Res (2008) 68 (9_Supplement): 1629.

Published: 01 May 2008

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Journal Articles

Human monoclonal antibody CP751871, combined with rapamycin is effective treatment for childhood sarcoma xenografts

Raushan Kurmasheva, Claire Boltz, Doris Phelps, Christopher Morton, Peter Houghton

Cancer Res (2008) 68 (9_Supplement): 3749.

Published: 01 May 2008

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Journal Articles

Defining the role of the type-1 insulin-like growth factor receptor (IGF-IR) signaling in childhood cancers in vitro and in vivo through use of a specific antibody (CP751871) targeting IGF-IR

Raushan Kurmasheva, Doris Phelps, Christopher Morton, Peter Houghton

Cancer Res (2007) 67 (9_Supplement): 4397.

Published: 01 May 2007

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NARROW

Abstract 668: A MYOD-SKP2 axis boosts oncogenic properties of fusion negative rhabdomyosarcoma and is counteracted by neddylation inhibition in vitro and in vivo

Abstract 3048: Surfaceome profiling identifies the immune checkpoint molecule B7-H3 as a key player of immune-evasion in rhabdomyosarcoma

Abstract B09: IL6 and CXCL8 mediate redundant tumor-host signaling pathways that facilitate osteosarcoma lung metastasis

Abstract 4873: Shedding light on the unknown of Ewing sarcoma: Single cell study shows a co-expression pattern between TAPA-1 and EWSR1-FLI1

Abstract 5825: Mechanisms of intrinsic and acquired resistance to antibodies targeting IGF-1R in pediatric sarcoma cell lines

Abstract B40: Autocrine and paracrine IL-6 and IL-8 drive osteosarcoma lung tropism and facilitate metastasis

Abstract 477: Inhibition of MEK confers hypersensitivity to X-radiation in the context of BRAF mutation in a model of childhood astrocytoma

Abstract A45: Autocrine and paracrine IL-6 and IL-8 drive osteosarcoma metastasis

Regulation of FANCD2 by the mTOR Pathway Contributes to the Resistance of Cancer Cells to DNA Double-Strand Breaks

Abstract 4437: Regulation of FANCD2 by the mTOR pathway contributes to the resistance of cancer cells to DNA double strand breaks.

Abstract 3277: Insulin-like growth factor-2 (IGF-2) circumvents the antiangiogenic activity of SCH717454, a human antibody that blocks ligand binding to the Type 1 insulin-like growth factor receptor (IGF-1R)

Molecular characterization of the Pediatric Preclinical Testing Program (PPTP) models

Human monoclonal antibody CP751871, combined with rapamycin is effective treatment for childhood sarcoma xenografts

Defining the role of the type-1 insulin-like growth factor receptor (IGF-IR) signaling in childhood cancers in vitro and in vivo through use of a specific antibody (CP751871) targeting IGF-IR

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