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Donna M. Peehl
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Journal Articles

Abstract 4166: The RNA demethylase FTO promotes glutamine metabolism in clear cell renal cell carcinoma through the regulation of SLC1A5

Man Zhao, Dalin Zhang, Haowen Jiang, Nishanth Kuganesan, Suchitra Natarajan, Leighton Pu, Kaushik N. Thakkar, Hongjuan Zhao, James D. Brooks, Donna M. Peehl, Jiangbin Ye, Erinn B. Rankin
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 4166.
https://doi.org/10.1158/1538-7445.AM2025-4166
Published: 21 April 2025
View articletitled, Abstract 4166: The RNA demethylase FTO promotes glutamine metabolism in clear cell renal cell carcinoma through the regulation of SLC1A5
Journal Articles

Abstract 4325: FXYD5 plays diverse roles in immune evasion and tumor progression in prostate cancer

Ru Wen, G Edward W. Marti, Neeladrisingha Das, Zhengyuan Qiu, Nathan Lam, Eric E. Peterson, Zenghua Fan, Aram Lyu, Fernando Jose Garcia Marques, Abel Bermudez, Hongjuan Zhao, Lawrence Fong, Guillem Pratx, Donna M. Peehl, Sharon J. Pitteri, James D. Brooks
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 4325.
https://doi.org/10.1158/1538-7445.AM2025-4325
Published: 21 April 2025
View articletitled, Abstract 4325: FXYD5 plays diverse roles in immune evasion and tumor progression in prostate cancer
Journal Articles

S100A10 Is a Critical Mediator of GAS6/AXL–Induced Angiogenesis in Renal Cell Carcinoma

Yiren Xiao, Hongjuan Zhao, Lei Tian, Rosalie Nolley, Anh N. Diep, Anne Ernst, Katherine C. Fuh, Yu Rebecca Miao, Rie von Eyben, John T. Leppert, James D. Brooks, Donna M. Peehl, Amato J. Giaccia, Erinn B. Rankin
Journal: Cancer Research
Cancer Res (2019) 79 (22): 5758–5768.
https://doi.org/10.1158/0008-5472.CAN-19-1366
Published: 15 November 2019
View articletitled, S100A10 Is a Critical Mediator of GAS6/AXL–Induced Angiogenesis in Renal Cell Carcinoma
Open the PDF for S100A10 Is a Critical Mediator of GAS6/AXL–Induced Angiogenesis in Renal Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 4358: The immunomodulatory anticancer agent RRx-001 induces a vaccine-like interferon response through epigenetic induction of viral mimicry

Hongjuan Zhao, Shoucheng Ning, Rosalie Nolley, Jan Scicinski, Bryan Oronsky, Susan J. Knox, Donna M. Peehl
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4358.
https://doi.org/10.1158/1538-7445.AM2017-4358
Published: 01 July 2017
View articletitled, Abstract 4358: The immunomodulatory anticancer agent RRx-001 induces a vaccine-like interferon response through epigenetic induction of viral mimicry
Journal Articles

Abstract 3515: RRx-001: A double action systemically non-toxic epigenetic agent for cancer therapy

Hongjuan Zhao, Shoucheng Ning, Jan Scicinski, Bryan Oronsky, Susan Knox, Donna M. Peehl
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3515.
https://doi.org/10.1158/1538-7445.AM2015-3515
Published: 01 August 2015
View articletitled, Abstract 3515: RRx-001: A double action systemically non-toxic epigenetic agent for cancer therapy
Journal Articles

Hepcidin Regulation in Prostate and Its Disruption in Prostate Cancer

Lia Tesfay, Kathryn A. Clausen, Jin Woo Kim, Poornima Hegde, Xiaohong Wang, Lance D. Miller, Zhiyong Deng, Nicole Blanchette, Tara Arvedson, Cindy K. Miranti, Jodie L. Babitt, Herbert Y. Lin, Donna M. Peehl, Frank M. Torti, Suzy V. Torti
Journal: Cancer Research
Cancer Res (2015) 75 (11): 2254–2263.
https://doi.org/10.1158/0008-5472.CAN-14-2465
Published: 31 May 2015
View articletitled, Hepcidin Regulation in Prostate and Its Disruption in Prostate Cancer
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Includes: Supplementary data
Journal Articles

Coordinate Loss of MAP3K7 and CHD1 Promotes Aggressive Prostate Cancer

Lindsey Ulkus Rodrigues, Leah Rider, Cera Nieto, Lina Romero, Anis Karimpour-Fard, Massimo Loda, M. Scott Lucia, Min Wu, Lihong Shi, Adela Cimic, S. Joseph Sirintrapun, Rosalie Nolley, Colton Pac, Haitao Chen, Donna M. Peehl, Jianfeng Xu, Wennuan Liu, James C. Costello, Scott D. Cramer
Journal: Cancer Research
Cancer Res (2015) 75 (6): 1021–1034.
https://doi.org/10.1158/0008-5472.CAN-14-1596
Published: 12 March 2015
View articletitled, Coordinate Loss of MAP3K7 and CHD1 Promotes Aggressive Prostate Cancer
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Journal Articles

Abstract 319: Expanding the experimental potential of a novel ex vivo model for primary human prostate cancer.

Sophia L. Maund, Rosalie Nolley, Donna M. Peehl
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 319.
https://doi.org/10.1158/1538-7445.AM2013-319
Published: 15 April 2013
View articletitled, Abstract 319: Expanding the experimental potential of a novel ex vivo model for primary human prostate cancer.
Journal Articles

Suppression of Tak1 Promotes Prostate Tumorigenesis

Min Wu, Lihong Shi, Adela Cimic, Lina Romero, Guangchao Sui, Cynthia J. Lees, J. Mark Cline, Darren F. Seals, Joseph S. Sirintrapun, Thomas P. McCoy, Wennuan Liu, Jin Woo Kim, Gregory A. Hawkins, Donna M. Peehl, Jianfeng Xu, Scott D. Cramer
Journal: Cancer Research
Cancer Res (2012) 72 (11): 2833–2843.
https://doi.org/10.1158/0008-5472.CAN-11-2724
Published: 31 May 2012
View articletitled, Suppression of Tak1 Promotes Prostate Tumorigenesis
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Includes: Supplementary data
Journal Articles

Centrosomal PKCβII and Pericentrin Are Critical for Human Prostate Cancer Growth and Angiogenesis

Jeewon Kim, Yoon-La Choi, Alice Vallentin, Ben S. Hunrichs, Marc K. Hellerstein, Donna M. Peehl, Daria Mochly-Rosen
Journal: Cancer Research
Cancer Res (2008) 68 (16): 6831–6839.
https://doi.org/10.1158/0008-5472.CAN-07-6195
Published: 12 August 2008
View articletitled, Centrosomal PKCβII and Pericentrin Are Critical for Human Prostate Cancer Growth and Angiogenesis
Open the PDF for Centrosomal PKCβII and Pericentrin Are Critical for Human Prostate Cancer Growth and Angiogenesis in another window
Includes: Supplementary data
Journal Articles

Topology of NGEP, a Prostate-Specific Cell:Cell Junction Protein Widely Expressed in Many Cancers of Different Grade Level

Sudipto Das, Yoonsoo Hahn, Dawn A. Walker, Satoshi Nagata, Mark C. Willingham, Donna M. Peehl, Tapan K. Bera, Byungkook Lee, Ira Pastan
Journal: Cancer Research
Cancer Res (2008) 68 (15): 6306–6312.
https://doi.org/10.1158/0008-5472.CAN-08-0870
Published: 01 August 2008
View articletitled, Topology of NGEP, a Prostate-Specific Cell:Cell Junction Protein Widely Expressed in Many Cancers of Different Grade Level
Open the PDF for Topology of NGEP, a Prostate-Specific Cell:Cell Junction Protein Widely Expressed in Many Cancers of Different Grade Level in another window
Includes: Supplementary data
Journal Articles

Inhibition of p38 by Vitamin D Reduces Interleukin-6 Production in Normal Prostate Cells via Mitogen-Activated Protein Kinase Phosphatase 5: Implications for Prostate Cancer Prevention by Vitamin D

Larisa Nonn, Lihong Peng, David Feldman, Donna M. Peehl
Journal: Cancer Research
Cancer Res (2006) 66 (8): 4516–4524.
https://doi.org/10.1158/0008-5472.CAN-05-3796
Published: 17 April 2006
View articletitled, Inhibition of p38 by Vitamin D Reduces Interleukin-6 Production in Normal Prostate Cells via Mitogen-Activated Protein Kinase Phosphatase 5: Implications for Prostate Cancer Prevention by Vitamin D
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Journal Articles

Vitamin D selectively decreases DNA damage in normal human primary prostate cells but not in prostate cancer cell lines

Larisa Nonn, Donna M. Peehl
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 451.
Published: 15 April 2006
View articletitled, Vitamin D selectively decreases DNA damage in normal human primary prostate cells but not in prostate cancer cell lines
Journal Articles

Regulation of Prostaglandin Metabolism by Calcitriol Attenuates Growth Stimulation in Prostate Cancer Cells

Jacqueline Moreno, Aruna V. Krishnan, Srilatha Swami, Larisa Nonn, Donna M. Peehl, David Feldman
Journal: Cancer Research
Cancer Res (2005) 65 (17): 7917–7925.
https://doi.org/10.1158/0008-5472.CAN-05-1435
Published: 01 September 2005
View articletitled, Regulation of Prostaglandin Metabolism by Calcitriol Attenuates Growth Stimulation in Prostate Cancer Cells
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Journal Articles

Expression of CCL5 (RANTES) and its receptors in prostate cancer

Gayle G. Vaday, Donna M. Peehl, Pournima A. Kadam, Diana M. Lawrence
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1108.
Published: 01 May 2005
View articletitled, Expression of CCL5 (RANTES) and its receptors in prostate cancer
Journal Articles

Identification of the major oxidative 3α-hydroxysteroid dehydrogenase in human prostate

David R. Bauman, Trevor M. Penning, Stephan Steckelbroeck, Donna M. Peehl
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 749.
Published: 01 May 2005
View articletitled, Identification of the major oxidative 3α-hydroxysteroid dehydrogenase in human prostate
Journal Articles

Retinol Metabolism and Lecithin:Retinol Acyltransferase Levels Are Reduced in Cultured Human Prostate Cancer Cells and Tissue Specimens

Xiaojia Guo, Beatrice S. Knudsen, Donna M. Peehl, Alberto Ruiz, Dean Bok, Robert R. Rando, Johng S. Rhim, David M. Nanus, Lorraine J. Gudas
Journal: Cancer Research
Cancer Res (2002) 62 (6): 1654–1661.
Published: 15 March 2002
View articletitled, Retinol Metabolism and Lecithin:Retinol Acyltransferase Levels Are Reduced in Cultured Human Prostate Cancer Cells and Tissue Specimens
Open the PDF for Retinol Metabolism and Lecithin:Retinol Acyltransferase Levels Are Reduced in Cultured Human Prostate Cancer Cells and Tissue Specimens in another window
Journal Articles

Reduced 1α-hydroxylase Activity in Human Prostate Cancer Cells Correlates with Decreased Susceptibility to 25-Hydroxyvitamin D3-induced Growth Inhibition

Ju-Yu Hsu, David Feldman, John E. McNeal, Donna M. Peehl
Journal: Cancer Research
Cancer Res (2001) 61 (7): 2852–2856.
Published: 01 April 2001
View articletitled, Reduced 1α-hydroxylase Activity in Human Prostate Cancer Cells Correlates with Decreased Susceptibility to 25-Hydroxyvitamin D3-induced Growth Inhibition
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Journal Articles

SMAD3 Represses Androgen Receptor-mediated Transcription

Steven A. Hayes, Mark Zarnegar, Manju Sharma, Fajun Yang, Donna M. Peehl, Peter ten Dijke, Zijie Sun
Journal: Cancer Research
Cancer Res (2001) 61 (5): 2112–2118.
Published: 01 March 2001
View articletitled, SMAD3 Represses Androgen Receptor-mediated Transcription
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Journal Articles

p16INK4A Mediates Cyclin Dependent Kinase 4 and 6 Inhibition in Senescent Prostatic Epithelial Cells

Charanjit Sandhu, Donna M. Peehl, Joyce Slingerland
Journal: Cancer Research
Cancer Res (2000) 60 (10): 2616–2622.
Published: 15 May 2000
View articletitled, p16INK4A Mediates Cyclin Dependent Kinase 4 and 6 Inhibition in Senescent Prostatic Epithelial Cells
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