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Journal Articles

N6-methyladenosine Modification of FZR1 mRNA Promotes Gemcitabine Resistance in Pancreatic Cancer

Jiachun Su, Rui Li, Ziming Chen, Shaoqiu Liu, Hongzhe Zhao, Shuang Deng, Lingxing Zeng, Zilan Xu, Sihan Zhao, Yifan Zhou, Mei Li, Xiaowei He, Ji Liu, Chunling Xue, Ruihong Bai, Lisha Zhuang, Quanbo Zhou, Shaoping Zhang, Rufu Chen, Xudong Huang, Dongxin Lin, Jian Zheng, Jialiang Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (18): 3059–3076.
https://doi.org/10.1158/0008-5472.CAN-22-3346
Published: 15 September 2023
View article titled, <em>N</em><sup>6</sup>-methyladenosine Modification of FZR1 mRNA Promotes Gemcitabine Resistance in Pancreatic Cancer
Open the PDF for <em>N</em><sup>6</sup>-methyladenosine Modification of FZR1 mRNA Promotes Gemcitabine Resistance in Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Computational Identification of Preneoplastic Cells Displaying High Stemness and Risk of Cancer Progression

Tianyuan Liu, Xuan Zhao, Yuan Lin, Qi Luo, Shaosen Zhang, Yiyi Xi, Yamei Chen, Lin Lin, Wenyi Fan, Jie Yang, Yuling Ma, Alok K. Maity, Yanyi Huang, Jianbin Wang, Jiang Chang, Dongxin Lin, Andrew E. Teschendorff, Chen Wu
Journal: Cancer Research
Cancer Res (2022) 82 (14): 2520–2537.
https://doi.org/10.1158/0008-5472.CAN-22-0668
Published: 18 July 2022
View article titled, Computational Identification of Preneoplastic Cells Displaying High Stemness and Risk of Cancer Progression
Open the PDF for Computational Identification of Preneoplastic Cells Displaying High Stemness and Risk of Cancer Progression in another window
Includes: Supplementary data
Journal Articles

CstF64-Induced Shortening of the BID 3′UTR Promotes Esophageal Squamous Cell Carcinoma Progression by Disrupting ceRNA Cross-talk with ZFP36L2

Ai Lin, Ping Ji, Xiangjie Niu, Xuan Zhao, Yamei Chen, Weiling Liu, Yachen Liu, Wenyi Fan, Yanxia Sun, Chuanwang Miao, Shaosen Zhang, Wen Tan, Dongxin Lin, Eric J. Wagner, Chen Wu
Journal: Cancer Research
Cancer Res (2021) 81 (22): 5638–5651.
https://doi.org/10.1158/0008-5472.CAN-21-1201
Published: 15 November 2021
View article titled, CstF64-Induced Shortening of the <em>BID</em> 3′UTR Promotes Esophageal Squamous Cell Carcinoma Progression by Disrupting ceRNA Cross-talk with <em>ZFP36L2</em>
Open the PDF for CstF64-Induced Shortening of the <em>BID</em> 3′UTR Promotes Esophageal Squamous Cell Carcinoma Progression by Disrupting ceRNA Cross-talk with <em>ZFP36L2</em> in another window
Includes: Supplementary data
Journal Articles

N6-methyladenosine–Mediated Upregulation of WTAPP1 Promotes WTAP Translation and Wnt Signaling to Facilitate Pancreatic Cancer Progression

Junge Deng, Jialiang Zhang, Ying Ye, Kaijing Liu, Lingxing Zeng, Jingyi Huang, Ling Pan, Mei Li, Ruihong Bai, Lisha Zhuang, Xudong Huang, Guandi Wu, Lusheng Wei, Yanfen Zheng, Jiachun Su, Shaoping Zhang, Rufu Chen, Dongxin Lin, Jian Zheng
Journal: Cancer Research
Cancer Res (2021) 81 (20): 5268–5283.
https://doi.org/10.1158/0008-5472.CAN-21-0494
Published: 15 October 2021
View article titled, <em>N<sup>6</sup></em>-methyladenosine–Mediated Upregulation of WTAPP1 Promotes WTAP Translation and Wnt Signaling to Facilitate Pancreatic Cancer Progression
Open the PDF for <em>N<sup>6</sup></em>-methyladenosine–Mediated Upregulation of WTAPP1 Promotes WTAP Translation and Wnt Signaling to Facilitate Pancreatic Cancer Progression in another window
Includes: Supplementary data
Journal Articles

Abstract LB-100: HNF4G overexpression promotes PDAC progression and confers metformin sensitivity in patients with SMAD4-loss of function

Chengcheng Wang, Chen Wu, Dongxin Lin, Yupei Zhao
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-100.
https://doi.org/10.1158/1538-7445.AM2019-LB-100
Published: 01 July 2019
View article titled, Abstract LB-100: HNF4G overexpression promotes PDAC progression and confers metformin sensitivity in patients with SMAD4-loss of function
Journal Articles

Abstract 3369: Mosaic chromosome X copy-number aberrations in leukocytes of never-smoking lung cancer patients: The Female Lung Cancer Consortium in Asia (FLCCA)

Jason Y. Wong, Mitchell Machiela, Weiyin Zhou, Wei Jie Seow, Bryan Bassig, Jinming Zhang, Meredith Yeager, Wei Zheng, Xiao-Ou Shu, Hongbing Shen, Keitaro Matsuo, Chao Agnes Hsiung, Maria P. Wong, Yun-Chul Hong, Jiu-cun Wang, Yi-Long Wu, Baosen Zhou, Robert Klein, Zhihua Yin, Tangchun Wu, Pan-Chyr Yang, Yong-Bing Xiang, Adeline Seow, Yu-Tang Gao, Chen Wu, Jianjun Liu, Zhibin Hu, Laurie Burdett, Qiuyin Cai, Juncheng Dai, Dongxin Lin, Kexin Chen, Stephen Chanock, Nathaniel Rothman, Qing Lan
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3369.
https://doi.org/10.1158/1538-7445.AM2018-3369
Published: 01 July 2018
View article titled, Abstract 3369: Mosaic chromosome X copy-number aberrations in leukocytes of never-smoking lung cancer patients: The Female Lung Cancer Consortium in Asia (FLCCA)
Journal Articles

Abstract LB-246: TIGAR amplification promotes glutamine addition in the progression of esophageal squamous cell carcinoma

Jiahui Chu, Mingming Shao, Jiang Chang, Qionghua Cui, Linna Peng, Yingying Luo, Wen Tan, Chen Wu, Dongxin Lin
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-246.
https://doi.org/10.1158/1538-7445.AM2018-LB-246
Published: 01 July 2018
View article titled, Abstract LB-246: <em>TIGAR</em> amplification promotes glutamine addition in the progression of esophageal squamous cell carcinoma
Journal Articles

Abstract LB-393: LINC01137 functions as a ceRNA promoting SMAD3 signaling and ESCC metastasis

Mingming Shao, Jiahui Chu, Qionghua Cui, Linna Peng, Yingying Luo, Jiang Chang, Wen Tan, Chen Wu, Dongxin Lin
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-393.
https://doi.org/10.1158/1538-7445.AM2018-LB-393
Published: 01 July 2018
View article titled, Abstract LB-393: LINC01137 functions as a ceRNA promoting SMAD3 signaling and ESCC metastasis
Journal Articles

Abstract 2568: Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

Qing Lan, Zhaoming Wang, Wei Jie Seow, Kouya Shiraishi, Hongbing Shen, Chao A. Hsiung, Keitaro Matsuo, Jie Liu, Kexin Chen, Taiki Yamji, Yang Yang, I-Shou Chang, Chen Wu, Meredith Yeager, Takashi Kohno, Wei Zheng, Xiao-Ou Shu, Pan-Chyr Yang, Tangchun Wu, Dongxin Lin, Baosen Zhou, Jinming Yu, Michiaki Kubo, Stephen J. Chanock, Nathaniel Rothman
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2568.
https://doi.org/10.1158/1538-7445.AM2016-2568
Published: 15 July 2016
View article titled, Abstract 2568: Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women
Journal Articles

Abstract 4598: Low-frequency coding variants in BAT2, HIST1H1E and BPIFB1 are associated with lung cancer risk in Chinese populations

Guangfu Jin, Meng Zhu, Rong Yin, Wei Shen, Lin Xu, Zhibin Hu, Dongxin Lin, Hongbing Shen
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4598.
https://doi.org/10.1158/1538-7445.AM2015-4598
Published: 01 August 2015
View article titled, Abstract 4598: Low-frequency coding variants in BAT2, HIST1H1E and BPIFB1 are associated with lung cancer risk in Chinese populations
Journal Articles

Abstract 4596: Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never-smoking women in Asia: A report from the Female Lung Cancer Consortium in Asia

Mitchell J. Machiela, Chao A. Hsiung, Xiao-Ou Shu, Wei J. Seow, Zhaoming Wang, Keitaro Matsuo, Yun-Chul Hong, Adeline Seow, Chen Wu, H Dean Hosgood, Kexin Chen, Jiu-Cun Wang, Wanqing Wen, Tangchun Wu, Maria P. Wong, Yi-Long Wu, Pan-Chyr Yang, Baosen Zhou, Min-Ho Shin, Joseph F. Fraumeni, Wei Zheng, Dongxin Lin, Stephen J. Chanock, Nathaniel Rothman, Qing Lan
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4596.
https://doi.org/10.1158/1538-7445.AM2015-4596
Published: 01 August 2015
View article titled, Abstract 4596: Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never-smoking women in Asia: A report from the Female Lung Cancer Consortium in Asia
Journal Articles

Abstract 3284: Genome-wide association study identifies new susceptibility loci of epithelial ovarian cancer in Han Chinese

Lian Li, Kexin Chen, Rongyu Zang, Quen Hao, Zhibin Hu, Dongxin Lin, Ding Ma, Weihua Jia, Hongbing Shen, Qingyi Wei
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3284.
https://doi.org/10.1158/1538-7445.AM2014-3284
Published: 01 October 2014
View article titled, Abstract 3284: Genome-wide association study identifies new susceptibility loci of epithelial ovarian cancer in Han Chinese
Journal Articles

Abstract 2204: Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations reveals new susceptibility loci

Chen Wu, Zhaoming Wang, Xin Song, Xiao-Shan Feng, Christian C. Abnet, Jie He, Nan Hu, Xian-Bo Zuo, Wen Tan, Xue-Jun Zhang, Neal D. Freedman, Alisa M. Goldstein, Dongxin Lin, Philip R. Taylor, Li-Dong Wang, Stephen J. Chanock
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2204.
https://doi.org/10.1158/1538-7445.AM2014-2204
Published: 01 October 2014
View article titled, Abstract 2204: Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations reveals new susceptibility loci
Journal Articles

Abstract 2543: A genome-wide analysis of ROHs identifies two susceptibility regions for non-cardia gastric cancer in han Chinese.

Zhibin Hu, Cheng Wang, Guangfu Jin, Dongxin Lin, Hongbing Shen
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2543.
https://doi.org/10.1158/1538-7445.AM2013-2543
Published: 15 April 2013
View article titled, Abstract 2543: A genome-wide analysis of ROHs identifies two susceptibility regions for non-cardia gastric cancer in han Chinese.
Journal Articles

Abstract 2545: Genome-wide association study identifies a novel susceptibility locus at 12q23.1 for lung squamous cell carcinoma in Chinese.

Hongbing Shen, Jing Dong, Guangfu Jin, Minjie Chu, Dongxin Lin, Zhinbin Hu
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2545.
https://doi.org/10.1158/1538-7445.AM2013-2545
Published: 15 April 2013
View article titled, Abstract 2545: Genome-wide association study identifies a novel susceptibility locus at 12q23.1 for lung squamous cell carcinoma in Chinese.
Journal Articles

Variations in HSPA1B at 6p21.3 Are Associated with Lung Cancer Risk and Prognosis in Chinese Populations

Huan Guo, Qifei Deng, Chen Wu, Lingmin Hu, Sheng Wei, Ping Xu, Dan Kuang, Li Liu, Zhibin Hu, Xiaoping Miao, Hongbing Shen, Dongxin Lin, Tangchun Wu
Journal: Cancer Research
Cancer Res (2011) 71 (24): 7576–7586.
https://doi.org/10.1158/0008-5472.CAN-11-1409
Published: 15 December 2011
View article titled, Variations in <em>HSPA1B</em> at 6p21.3 Are Associated with Lung Cancer Risk and Prognosis in Chinese Populations
Open the PDF for Variations in <em>HSPA1B</em> at 6p21.3 Are Associated with Lung Cancer Risk and Prognosis in Chinese Populations in another window
Includes: Supplementary data
Journal Articles

Genetic Variation in an miRNA-1827 Binding Site in MYCL1 Alters Susceptibility to Small-Cell Lung Cancer

Fang Xiong, Chen Wu, Jiang Chang, Dianke Yu, Binghe Xu, Peng Yuan, Kan Zhai, Jian Xu, Wen Tan, Dongxin Lin
Journal: Cancer Research
Cancer Res (2011) 71 (15): 5175–5181.
https://doi.org/10.1158/0008-5472.CAN-10-4407
Published: 28 July 2011
View article titled, Genetic Variation in an miRNA-1827 Binding Site in <em>MYCL1</em> Alters Susceptibility to Small-Cell Lung Cancer
Open the PDF for Genetic Variation in an miRNA-1827 Binding Site in <em>MYCL1</em> Alters Susceptibility to Small-Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Genome-Wide Interrogation Identifies YAP1 Variants Associated with Survival of Small-Cell Lung Cancer Patients

Chen Wu, Binghe Xu, Peng Yuan, Xiaoping Miao, Yu Liu, Yin Guan, Dianke Yu, Jian Xu, Tongwen Zhang, Hongbing Shen, Tangchun Wu, Dongxin Lin
Journal: Cancer Research
Cancer Res (2010) 70 (23): 9721–9729.
https://doi.org/10.1158/0008-5472.CAN-10-1493
Published: 06 December 2010
View article titled, Genome-Wide Interrogation Identifies <em>YAP1</em> Variants Associated with Survival of Small-Cell Lung Cancer Patients
Open the PDF for Genome-Wide Interrogation Identifies <em>YAP1</em> Variants Associated with Survival of Small-Cell Lung Cancer Patients in another window
Includes: Supplementary data
Journal Articles

Abstract 2764: Genome-wide examination of genetic variants associated with response to platinum-based chemotherapy in patients with small-cell lung cancer

Chen Wu, Binghe Xu, Peng Yuan, Jurg Ott, Yin Guan, Yu Liu, Yuanyuan Shen, Zhe Liu, Dianke Yu, Dongxin Lin
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2764.
https://doi.org/10.1158/1538-7445.AM10-2764
Published: 15 April 2010
View article titled, Abstract 2764: Genome-wide examination of genetic variants associated with response to platinum-based chemotherapy in patients with small-cell lung cancer
Journal Articles

Genetic Polymorphisms in Cytotoxic T-Lymphocyte Antigen 4 and Cancer: The Dialectical Nature of Subtle Human Immune Dysregulation

Tong Sun, Zhibin Hu, Hongbing Shen, Dongxin Lin
Journal: Cancer Research
Cancer Res (2009) 69 (15): 6011–6014.
https://doi.org/10.1158/0008-5472.CAN-09-0176
Published: 29 July 2009
View article titled, Genetic Polymorphisms in <em>Cytotoxic T-Lymphocyte Antigen 4</em> and Cancer: The Dialectical Nature of Subtle Human Immune Dysregulation
Open the PDF for Genetic Polymorphisms in <em>Cytotoxic T-Lymphocyte Antigen 4</em> and Cancer: The Dialectical Nature of Subtle Human Immune Dysregulation in another window