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Journal Articles

Abstract 3337: The impact of black raspberry as a whole food approach on DNA damage-induced by tobacco carcinogens in the oral cavity and urine of smokers

Kun-Ming Chen, Yuan-Wan Sun, Nicolle M. Krebs, Lisa Reinhart, Dongxiao Sun, Elizabeth P. Bond, Jacek Krzeminski, Krishne Gowda, Shantu Amin, Susan Mallery, John P. Richie, Karam El-Bayoumy
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3337.
https://doi.org/10.1158/1538-7445.AM2023-3337
Published: 04 April 2023
View articletitled, Abstract 3337: The impact of black raspberry as a whole food approach on DNA damage-induced by tobacco carcinogens in the oral cavity and urine of smokers
Journal Articles

Mitochondrial Calcium Uniporter Drives Metastasis and Confers a Targetable Cystine Dependency in Pancreatic Cancer

Xiuchao Wang, Yunzhan Li, Zekun Li, Shengchen Lin, Hongwei Wang, Jianwei Sun, Chungen Lan, Liangliang Wu, Dongxiao Sun, Chongbiao Huang, Pankaj K. Singh, Nadine Hempel, Mohamed Trebak, Gina M. DeNicola, Jihui Hao, Shengyu Yang
Journal: Cancer Research
Cancer Res (2022) 82 (12): 2254–2268.
https://doi.org/10.1158/0008-5472.CAN-21-3230
Published: 15 June 2022
View articletitled, Mitochondrial Calcium Uniporter Drives Metastasis and Confers a Targetable Cystine Dependency in Pancreatic Cancer
Open the PDF for Mitochondrial Calcium Uniporter Drives Metastasis and Confers a Targetable Cystine Dependency in Pancreatic Cancer in another window
Includes: Multimedia, Supplementary data
Journal Articles

Abstract 2203: Characterization of raloxifene glucuronidation and the role of UGT genotypes on raloxifene metabolite profiles in vivo.

Dongxiao Sun, Nathan R. Jones, Manni Andrea, Philip Lazarus
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2203.
https://doi.org/10.1158/1538-7445.AM2013-2203
Published: 15 April 2013
View articletitled, Abstract 2203: Characterization of raloxifene glucuronidation and the role of UGT genotypes on raloxifene metabolite profiles in vivo.
Journal Articles

Abstract 3089: miR-491-3p regulation of the UDP-glucuronosyltransferase (UGT) 1A gene family.

Douglas F. Dluzen, Anna Salzberg, Dongxiao Sun, Nathan Jones, Ryan Bushey', Philip Lazarus
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3089.
https://doi.org/10.1158/1538-7445.AM2013-3089
Published: 15 April 2013
View articletitled, Abstract 3089: miR-491-3p regulation of the UDP-glucuronosyltransferase (UGT) 1A gene family.
Journal Articles

Abstract 712: Characterization of exemestane metabolic pathways

Dongxiao Sun, Ying Liu, Diane E. McCloskey, Philip Lazarus
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 712.
https://doi.org/10.1158/1538-7445.AM2011-712
Published: 15 April 2011
View articletitled, Abstract 712: Characterization of exemestane metabolic pathways
Journal Articles

Abstract 3589: Characterization of 17-dihydroexemestane glucuronidation. A role for the UGT2B17 deletion in exemestane pharmacogenetics

Dongxiao Sun, Gang Chen, Ryan W. Dellinger, Arun K. Sharma, Philip Lazarus
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3589.
https://doi.org/10.1158/1538-7445.AM10-3589
Published: 15 April 2010
View articletitled, Abstract 3589: Characterization of 17-dihydroexemestane glucuronidation. A role for the UGT2B17 deletion in exemestane pharmacogenetics
Journal Articles

Abstract 3456: Characterization of dibenzo[a,l]pyrene-trans-11,12-diol glucuronidation by UDP-glucuronosyltransferases

Kristine C. Olson, Dongxiao Sun, Gang Chen, Arun K. Sharma, Shantu Amin, Ira J. Ropson, Thomas E. Spratt, Philip Lazarus
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3456.
https://doi.org/10.1158/1538-7445.AM10-3456
Published: 15 April 2010
View articletitled, Abstract 3456: Characterization of dibenzo[a,l]pyrene-trans-11,12-diol glucuronidation by UDP-glucuronosyltransferases
Journal Articles

Characterization of UGTs Active against SAHA and Association between SAHA Glucuronidation Activity Phenotype with UGT Genotype

Renee M. Balliet, Gang Chen, Carla J. Gallagher, Ryan W. Dellinger, Dongxiao Sun, Philip Lazarus
Journal: Cancer Research
Cancer Res (2009) 69 (7): 2981–2989.
https://doi.org/10.1158/0008-5472.CAN-08-4143
Published: 01 April 2009
View articletitled, Characterization of UGTs Active against SAHA and Association between SAHA Glucuronidation Activity Phenotype with UGT Genotype
Open the PDF for Characterization of UGTs Active against SAHA and Association between SAHA Glucuronidation Activity Phenotype with UGT Genotype in another window
Journal Articles

Functional Significance of UDP-Glucuronosyltransferase Variants in the Metabolism of Active Tamoxifen Metabolites

Andrea S. Blevins-Primeau, Dongxiao Sun, Gang Chen, Arun K. Sharma, Carla J. Gallagher, Shantu Amin, Philip Lazarus
Journal: Cancer Research
Cancer Res (2009) 69 (5): 1892–1900.
https://doi.org/10.1158/0008-5472.CAN-08-3708
Published: 02 March 2009
View articletitled, Functional Significance of UDP-Glucuronosyltransferase Variants in the Metabolism of Active Tamoxifen Metabolites
Open the PDF for Functional Significance of UDP-Glucuronosyltransferase Variants in the Metabolism of Active Tamoxifen Metabolites in another window
Journal Articles

Glucuronidation of tamoxifen metabolites by UGTs. Potential role of UGTs variants in tamoxifen metabolism

Dongxiao Sun, Andrea Blevins-Primeau, Ryan Dellinger, Arun Sharma, Renee Balliet, Philip Lazarus
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4703.
Published: 01 May 2008
View articletitled, Glucuronidation of tamoxifen metabolites by UGTs. Potential role of UGTs variants in tamoxifen metabolism
Journal Articles

Genotype-phenotype correlation between the polymorphic UDP-glucuronosyltransferase 2B7 and O-glucuronidation of the major active metabolites of tamoxifen

Andrea Blevins-Primeau, Gang Chen, Dongxiao Sun, Arun Sharma, Shantu Amin, Philip Lazarus
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4803.
Published: 01 May 2008
View articletitled, Genotype-phenotype correlation between the polymorphic UDP-glucuronosyltransferase 2B7 and O-glucuronidation of the major active metabolites of tamoxifen
Journal Articles

Dimerization-dependent glucuronidation by UGT1A9

Ryan Dellinger, Dongxiao Sun, Gang Chen, Qing Zhong, Philip Lazarus
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4695.
Published: 01 May 2008
View articletitled, Dimerization-dependent glucuronidation by UGT1A9
Journal Articles

Identification and characterization of UGTs responsible for suberoylanilide hydroxamic acid (SAHA) glucuronidation.

Renee Balliet, Gang Chen, Ryan Dellinger, Dongxiao Sun, Dhimant Desai, Shantu Amin, Philip Lazarus
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 730.
Published: 01 May 2008
View articletitled, Identification and characterization of UGTs responsible for suberoylanilide hydroxamic acid (SAHA) glucuronidation.
Journal Articles

UGT2B10 is a major glucuronidator of tobacco-specific nitrosamines; association of UGT2B10 haplotypes with glucuronidation phenotypes in humans

Gang Chen, Ryan Dellinger, Carla Gallagher, Dongxiao Sun, Gary Chase, Thomas Spratt, Joshua Muscat, John Richie, Amy Hicks, Philip Lazarus
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4236.
Published: 01 May 2007
View articletitled, UGT2B10 is a major glucuronidator of tobacco-specific nitrosamines; association of UGT2B10 haplotypes with glucuronidation phenotypes in humans
Journal Articles

Glucuronidation of the active metabolites of tamoxifen by human liver microsome and individual UDP-glucuronosyltransferases (UGTs)

Dongxiao Sun, Gang Chen, Ryan Dellinger, L. Michael Carastro, R. Bronwyn Weinberg, Qing Zhong, Philip Lazarus
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 732.
Published: 15 April 2006
View articletitled, Glucuronidation of the active metabolites of tamoxifen by human liver microsome and individual UDP-glucuronosyltransferases (UGTs)
Journal Articles

Glucuronidation of tobacco-specific nitrosamines by human UGTs.

Gang Chen, Ryan Dellinger, R. Bronwyn Weinberg, Dongxiao Sun, Philip Lazarus
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1231.
Published: 15 April 2006
View articletitled, Glucuronidation of tobacco-specific nitrosamines by human UGTs.
Journal Articles

Glucuronidation of tamoxifen and 4-hydroxytamoxifen by human UGT1A4 variants

Dongxiao Sun, Kimberly Duncan, Gang Chen, Ryan Dellinger, L. Michael Carastro, Philip Lazarus
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1160.
Published: 01 May 2005
View articletitled, Glucuronidation of tamoxifen and 4-hydroxytamoxifen by human UGT1A4 variants