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Abstract 5875: Germline gene alterations in high grade and low grade gliomas: A multi-center, large scale study in China

Jie Wang, Bella Guo, Xiang Zhang, Ximeng Zhao, Dongsheng Wang, Fei Sun, Tonghui Ma

Cancer Res (2022) 82 (12_Supplement): 5875.

DOI: https://doi.org/10.1158/1538-7445.AM2022-5875

Published: 15 June 2022

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Journal Articles

Abstract 428: Therapeutic potential of the novel SHP2 degrader, SHP2-D26, alone or in combination, in the treatment of lung cancer

Yunful Deng, Guangzhi Ma, Karin A. Vallega, Dongsheng Wang, Mingliang Wang, Changwei Wang, Shaomeng Wang, Suresh S. Ramalingam, Shi-Yong Sun

Cancer Res (2022) 82 (12_Supplement): 428.

DOI: https://doi.org/10.1158/1538-7445.AM2022-428

Published: 15 June 2022

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Journal Articles

The Proteomic Landscape of Growth Factor Signaling Networks Associated with FAT1 Mutations in Head and Neck Cancers

Zhengjia Chen, Chao Zhang, Jianhong Chen, Dongsheng Wang, Jieqi Tu, Carter Van Waes, Nabil F. Saba, Zhuo G. Chen, Zhong Chen

Cancer Res (2021) 81 (17): 4402–4416.

DOI: https://doi.org/10.1158/0008-5472.CAN-20-3659

Published: 01 September 2021

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Includes: Supplementary data

Journal Articles

Abstract 321: Identification of proteins associated with FAT1 mutations which potentially contribute to oncogenesis and progression of head and neck cancers

Zhuo Georgia Chen, Zhengjia Chen, Chao Zhang, Jianhong Chen, Dongsheng Wang, Nabil F. Saba, Zhong Chen

Cancer Res (2021) 81 (13_Supplement): 321.

DOI: https://doi.org/10.1158/1538-7445.AM2021-321

Published: 01 July 2021

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Journal Articles

Abstract 2980: Effects of cetuximab and CD-3379 on cytokine/chemokine balance in the tumor micro-environment (TME) of squamous cell carcinoma of the head and neck (SCCHN)

Dongsheng Wang, Sreenivas Nannapaneni, Gregory B. Lesinski, Dong M. Shin, Nabil F. Saba, Georgia Z. Chen

Cancer Res (2020) 80 (16_Supplement): 2980.

DOI: https://doi.org/10.1158/1538-7445.AM2020-2980

Published: 15 August 2020

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Journal Articles

mTORC2 Suppresses GSK3-Dependent Snail Degradation to Positively Regulate Cancer Cell Invasion and Metastasis

Shuo Zhang, Guoqing Qian, Qian-Qian Zhang, Yuying Yao, Dongsheng Wang, Zhuo G. Chen, Li-Jing Wang, Mingwei Chen, Shi-Yong Sun

Cancer Res (2019) 79 (14): 3725–3736.

DOI: https://doi.org/10.1158/0008-5472.CAN-19-0180

Published: 15 July 2019

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Includes: Supplementary data

Journal Articles

Abstract 4598: mTORC2 suppresses GSK3-dependent, but b-TrCP-independent, Snail degradation, contributing to positive regulation of cancer cell invasion and metastasis

Shuo Zhang, Guoqing Qian, Qian-Qian Zhang, Yuying Yao, DongSheng Wang, Zhuo G. Chen, Lijing Wang, Mingwei Chen, Shi-Yong Sun

Cancer Res (2019) 79 (13_Supplement): 4598.

DOI: https://doi.org/10.1158/1538-7445.AM2019-4598

Published: 01 July 2019

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Journal Articles

Abstract 4834: Effective treatment of squamous cell carcinoma of the head and neck (HNSCC) using a combined regimen of tipifarnib and cetuximab

Lihua Shu, Dongsheng Wang, Sreenivas Nannapaneni, Dong M. Shin, Nabil F. Saba, Georgia Z. Chen

Cancer Res (2019) 79 (13_Supplement): 4834.

DOI: https://doi.org/10.1158/1538-7445.AM2019-4834

Published: 01 July 2019

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Journal Articles

Abstract 3951: NVP-BEZ235 decreases mutant p53 and affects miR-23a-24a-27a to inhibit metastasis in breast cancer cells

Jiajing Cai, Jingruo Xia, Dan Xiao, Chang Liu, Hebin Liao, Lei Xu, Dongsheng Wang, Xiaolan Guo

Cancer Res (2018) 78 (13_Supplement): 3951.

DOI: https://doi.org/10.1158/1538-7445.AM2018-3951

Published: 01 July 2018

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Journal Articles

Abstract 3701: Targeted Bcl2 siRNA delivery using DNA nanoparticles in cancer therapy

Mohammad Aminur Rahman, Pengfei Wang, Dongsheng Wang, Sreenivas Nannapaneni, Selwyn J. Hurwitz, Zhuo G. Chen, Yonggang Ke, Dong M. Shin

Cancer Res (2018) 78 (13_Supplement): 3701.

DOI: https://doi.org/10.1158/1538-7445.AM2018-3701

Published: 01 July 2018

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Journal Articles

Abstract 876: Effective reduction of PD-L1 expression by simultaneous blockade of EGFR and HER3 (ErbB3) in head and neck cancer

Zhuo Georgia Chen, Dongsheng Wang, Christopher C. Griffith, Sreenivas Nannapaneni, Conor Steuer, Mihir R. Patel, Mark W. El-Deiry, Xu Wang, Yuzi Zhang, Zhengjia Chen, Diego Alvarado, Dong M. Shin, Nabil F. Saba

Cancer Res (2018) 78 (13_Supplement): 876.

DOI: https://doi.org/10.1158/1538-7445.AM2018-876

Published: 01 July 2018

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Journal Articles

Abstract 4110: Combinatory approaches targeting EGFR, HER2 and c-MET in recurrent SCCHN

Dongsheng Wang, Kelly R. Magliocca, Sreenivas Nannapaneni, Coner Steuer, Mihir R. Patel, Mark W. El-Deiry, Xu Wang, Zhengjia Chen, Dong M. Shin, Nabil F. Saba, Zhuo G. Chen

Cancer Res (2017) 77 (13_Supplement): 4110.

DOI: https://doi.org/10.1158/1538-7445.AM2017-4110

Published: 01 July 2017

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Journal Articles

Abstract 187: Efficient delivery of Bcl2 siRNA by DNA nanoparticles to inhibit cellular growth and cancer progression

Mohammad Aminur Rahman, Pengfei Wang, Dongsheng Wang, Selwyn J. Hurwitz, Zhengjia Chen, Zhuo G. Chen, Yonggang Ke, Dong M. Shin

Cancer Res (2017) 77 (13_Supplement): 187.

DOI: https://doi.org/10.1158/1538-7445.AM2017-187

Published: 01 July 2017

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Journal Articles

Abstract 2577: Expression of P53/PTEN/c-Myc in peripheral blood leukocytes from patients with breast cancer and its clinical significance

Guangcheng Huang, Qiang Ma, Jiang Zou, Ru Sun, Lihua Yao, Lei Xu, Dongsheng Wang, Xiaolan Guo

Cancer Res (2017) 77 (13_Supplement): 2577.

DOI: https://doi.org/10.1158/1538-7445.AM2017-2577

Published: 01 July 2017

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Journal Articles

Abstract 1866: HER3 targeting sensitizes HNSCC to cetuximab - evidence from cell line and patient derived xenograft (PDX) models

Dongsheng Wang, Guoqing Qian, hongzheng zhang, kelly R. Magliocca, sreenivas nannapaneni, zhengjia chen, mihir R. patel, Mark W. El-Deiry, J.trad Wadsworth, dong M. Shin, fadlo R. khuri, Nabil F. Saba, Zhuo G. chen

Cancer Res (2016) 76 (14_Supplement): 1866.

DOI: https://doi.org/10.1158/1538-7445.AM2016-1866

Published: 15 July 2016

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Journal Articles

Abstract 1678: DRAM1 regulates EMT of lung cancer A549 cells via SQSTM1/p62 in vitro

Binfeng He, Jiajing Cai, Guangcheng Huang, Fan Chang, Lei Xu, Dongsheng Wang, Yibin Deng, Xiaolan Guo

Cancer Res (2016) 76 (14_Supplement): 1678.

DOI: https://doi.org/10.1158/1538-7445.AM2016-1678

Published: 15 July 2016

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Journal Articles

Abstract 1226: Association of p53 codon72 polymorphism with susceptibility to hepatocellular carcinoma in Chinese population of Northeast Sichuan

Jiajing Cai, Yan Cai, Qiang Ma, Dongsheng Wang, Guoyuan Zhang, Xiaolan Guo

Cancer Res (2015) 75 (15_Supplement): 1226.

DOI: https://doi.org/10.1158/1538-7445.AM2015-1226

Published: 01 August 2015

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Journal Articles

Abstract 4470: Targeting autophagy and apoptosis to enhance anticancer effect on esophageal carcinoma in vitro

Yan Cai, Jiajing Cai, Qiang Ma, Yuan Xu, Dongsheng Wang, Xiaolan Guo

Cancer Res (2015) 75 (15_Supplement): 4470.

DOI: https://doi.org/10.1158/1538-7445.AM2015-4470

Published: 01 August 2015

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Journal Articles

Abstract 813: Human papillomavirus 16 oncoprotein E6 upregulates c-Met partially through p53 in squamous cell carcinoma of the head and neck

Guoqing Qian, Dongsheng Wang, Kelly R. Magliocca, Praveen Duggal, Sreenivas Nannapaneni, Sungjin Kim, Zhengjia Chen, Dong M. Shin, Nabil F. Saba, Zhuo G. Chen

Cancer Res (2015) 75 (15_Supplement): 813.

DOI: https://doi.org/10.1158/1538-7445.AM2015-813

Published: 01 August 2015

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Journal Articles

Abstract 584: NVP-BEZ235 decreases mutant p53 and downregulates miR-23a-24-27a to inhibit metastasis in breast cancer cells

Dongsheng Wang, Qin Du, Binfeng He, Yibin Deng, Xiaolan Guo

Cancer Res (2014) 74 (19_Supplement): 584.

DOI: https://doi.org/10.1158/1538-7445.AM2014-584

Published: 01 October 2014

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NARROW

Abstract 5875: Germline gene alterations in high grade and low grade gliomas: A multi-center, large scale study in China

Abstract 428: Therapeutic potential of the novel SHP2 degrader, SHP2-D26, alone or in combination, in the treatment of lung cancer

The Proteomic Landscape of Growth Factor Signaling Networks Associated with FAT1 Mutations in Head and Neck Cancers

Abstract 321: Identification of proteins associated with FAT1 mutations which potentially contribute to oncogenesis and progression of head and neck cancers

Abstract 2980: Effects of cetuximab and CD-3379 on cytokine/chemokine balance in the tumor micro-environment (TME) of squamous cell carcinoma of the head and neck (SCCHN)

mTORC2 Suppresses GSK3-Dependent Snail Degradation to Positively Regulate Cancer Cell Invasion and Metastasis

Abstract 4598: mTORC2 suppresses GSK3-dependent, but b-TrCP-independent, Snail degradation, contributing to positive regulation of cancer cell invasion and metastasis

Abstract 4834: Effective treatment of squamous cell carcinoma of the head and neck (HNSCC) using a combined regimen of tipifarnib and cetuximab

Abstract 3951: NVP-BEZ235 decreases mutant p53 and affects miR-23a-24a-27a to inhibit metastasis in breast cancer cells

Abstract 3701: Targeted Bcl2 siRNA delivery using DNA nanoparticles in cancer therapy

Abstract 876: Effective reduction of PD-L1 expression by simultaneous blockade of EGFR and HER3 (ErbB3) in head and neck cancer

Abstract 4110: Combinatory approaches targeting EGFR, HER2 and c-MET in recurrent SCCHN

Abstract 187: Efficient delivery of Bcl2 siRNA by DNA nanoparticles to inhibit cellular growth and cancer progression

Abstract 2577: Expression of P53/PTEN/c-Myc in peripheral blood leukocytes from patients with breast cancer and its clinical significance

Abstract 1866: HER3 targeting sensitizes HNSCC to cetuximab - evidence from cell line and patient derived xenograft (PDX) models

Abstract 1678: DRAM1 regulates EMT of lung cancer A549 cells via SQSTM1/p62 in vitro

Abstract 1226: Association of p53 codon72 polymorphism with susceptibility to hepatocellular carcinoma in Chinese population of Northeast Sichuan

Abstract 4470: Targeting autophagy and apoptosis to enhance anticancer effect on esophageal carcinoma in vitro

Abstract 813: Human papillomavirus 16 oncoprotein E6 upregulates c-Met partially through p53 in squamous cell carcinoma of the head and neck

Abstract 584: NVP-BEZ235 decreases mutant p53 and downregulates miR-23a-24-27a to inhibit metastasis in breast cancer cells

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