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Journal Articles

Abstract CT037: Early-phase trial of IAP antagonist tolinapant and definitive radiation in cisplatin-ineligible patients with previously untreated, locally advanced head and neck cancer

Nicole C. Schmitt, William A. Stokes, James E. Bates, Jill Remick, Mark McDonald, Soumon Rudra, Brendan L. Kinney, Madison Steininger, Mosope Oyewole, Azeem S. Kaka, Jennifer H. Gross, Mihir R. Patel, Dong M. Shin, Conor Steuer, Nabil F. Saba

Cancer Res (2025) 85 (8_Supplement_2): CT037.

https://doi.org/10.1158/1538-7445.AM2025-CT037

Published: 25 April 2025

View articletitled, Abstract CT037: Early-phase trial of IAP antagonist tolinapant and definitive radiation in cisplatin-ineligible patients with previously untreated, locally advanced head and neck cancer

Journal Articles

Abstract 500: Neuropsychological symptoms in patients with head and neck cancer undergoing radiation therapy: A network analysis

Yufen Lin, Deborah W. Bruner, Sudeshna Paul, Andrew H. Miller, Nabil F. Saba, Kristin A. Higgins, Dong M. Shin, Wenhui Zhang, Christine Miaskowski, Canhua Xiao

Cancer Res (2022) 82 (12_Supplement): 500.

https://doi.org/10.1158/1538-7445.AM2022-500

Published: 15 June 2022

View articletitled, Abstract 500: Neuropsychological symptoms in patients with head and neck cancer undergoing radiation therapy: A network analysis

Journal Articles

Abstract PO-033: Metabolic differences between human papillomavirus-related and smoking-related squamous cell carcinoma of the head and neck independently predict overall patient survival

Ronald C. Eldridge, Karan Uppal, Jonathan Beitler, Kristin Higgins, Evanthia C. Wommack, Dong M. Shin, Nabil F. Saba, Andrew Miller, Deborah W. Bruner, Canhua Xiao

Cancer Res (2020) 80 (23_Supplement): PO-033.

https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-033

Published: 02 December 2020

View articletitled, Abstract PO-033: Metabolic differences between human papillomavirus-related and smoking-related squamous cell carcinoma of the head and neck independently predict overall patient survival

Journal Articles

Abstract 2980: Effects of cetuximab and CD-3379 on cytokine/chemokine balance in the tumor micro-environment (TME) of squamous cell carcinoma of the head and neck (SCCHN)

Dongsheng Wang, Sreenivas Nannapaneni, Gregory B. Lesinski, Dong M. Shin, Nabil F. Saba, Georgia Z. Chen

Cancer Res (2020) 80 (16_Supplement): 2980.

https://doi.org/10.1158/1538-7445.AM2020-2980

Published: 15 August 2020

View articletitled, Abstract 2980: Effects of cetuximab and CD-3379 on cytokine/chemokine balance in the tumor micro-environment (TME) of squamous cell carcinoma of the head and neck (SCCHN)

Journal Articles

Abstract 1907: Src-Met signaling confers apoptosis resistance to EGFR and PI3K co-targeting independently of AKT and ERK pathway activation in head and neck cancer

Abu S. Anisuzzaman, Abedul Haque, Zhuo G. Chen, Dong M. Shin, A.R.M. Ruhul Amin

Cancer Res (2020) 80 (16_Supplement): 1907.

https://doi.org/10.1158/1538-7445.AM2020-1907

Published: 15 August 2020

View articletitled, Abstract 1907: Src-Met signaling confers apoptosis resistance to EGFR and PI3K co-targeting independently of AKT and ERK pathway activation in head and neck cancer

Journal Articles

Abstract 4097: TMV vaccine inhibits growth of squamous cell carcinoma of head and neck in mice

Ramireddy Bommireddy, Luis Munoz, Chrstopher D. Pack, Sampath Ramachandiran, Shaker JC Reddy, Janet Kim, Georgia Chen, Nabil F. Saba, Dong M. Shin, Periasamy Selvaraj

Cancer Res (2019) 79 (13_Supplement): 4097.

https://doi.org/10.1158/1538-7445.AM2019-4097

Published: 01 July 2019

View articletitled, Abstract 4097: TMV vaccine inhibits growth of squamous cell carcinoma of head and neck in mice

Journal Articles

Abstract 4834: Effective treatment of squamous cell carcinoma of the head and neck (HNSCC) using a combined regimen of tipifarnib and cetuximab

Lihua Shu, Dongsheng Wang, Sreenivas Nannapaneni, Dong M. Shin, Nabil F. Saba, Georgia Z. Chen

Cancer Res (2019) 79 (13_Supplement): 4834.

https://doi.org/10.1158/1538-7445.AM2019-4834

Published: 01 July 2019

View articletitled, Abstract 4834: Effective treatment of squamous cell carcinoma of the head and neck (HNSCC) using a combined regimen of tipifarnib and cetuximab

Journal Articles

Abstract 4257: Predicting fatigue levels of head and neck cancer patients with gene expression using machine learning

Ronald C. Eldridge, Andrew H. Miller, Deborah W. Bruner, Jonathan J. Beitler, Kristin A. Higgins, Evanthia C. Wommack, Linh Kha Huynh, Nabil F. Saba, Dong M. Shin, Canhua Xiao

Cancer Res (2018) 78 (13_Supplement): 4257.

https://doi.org/10.1158/1538-7445.AM2018-4257

Published: 01 July 2018

View articletitled, Abstract 4257: Predicting fatigue levels of head and neck cancer patients with gene expression using machine learning

Journal Articles

Abstract 876: Effective reduction of PD-L1 expression by simultaneous blockade of EGFR and HER3 (ErbB3) in head and neck cancer

Zhuo Georgia Chen, Dongsheng Wang, Christopher C. Griffith, Sreenivas Nannapaneni, Conor Steuer, Mihir R. Patel, Mark W. El-Deiry, Xu Wang, Yuzi Zhang, Zhengjia Chen, Diego Alvarado, Dong M. Shin, Nabil F. Saba

Cancer Res (2018) 78 (13_Supplement): 876.

https://doi.org/10.1158/1538-7445.AM2018-876

Published: 01 July 2018

View articletitled, Abstract 876: Effective reduction of PD-L1 expression by simultaneous blockade of EGFR and HER3 (ErbB3) in head and neck cancer

Journal Articles

Abstract 3701: Targeted Bcl2 siRNA delivery using DNA nanoparticles in cancer therapy

Mohammad Aminur Rahman, Pengfei Wang, Dongsheng Wang, Sreenivas Nannapaneni, Selwyn J. Hurwitz, Zhuo G. Chen, Yonggang Ke, Dong M. Shin

Cancer Res (2018) 78 (13_Supplement): 3701.

https://doi.org/10.1158/1538-7445.AM2018-3701

Published: 01 July 2018

View articletitled, Abstract 3701: Targeted Bcl2 siRNA delivery using DNA nanoparticles in cancer therapy

Journal Articles

Abstract 4110: Combinatory approaches targeting EGFR, HER2 and c-MET in recurrent SCCHN

Dongsheng Wang, Kelly R. Magliocca, Sreenivas Nannapaneni, Coner Steuer, Mihir R. Patel, Mark W. El-Deiry, Xu Wang, Zhengjia Chen, Dong M. Shin, Nabil F. Saba, Zhuo G. Chen

Cancer Res (2017) 77 (13_Supplement): 4110.

https://doi.org/10.1158/1538-7445.AM2017-4110

Published: 01 July 2017

View articletitled, Abstract 4110: Combinatory approaches targeting EGFR, HER2 and c-MET in recurrent SCCHN

Journal Articles

Abstract 175: Combination of plasmonic photothermal therapy with surgery applied to naturally occurring mammary tumors in canines and felines: clinical outcomes and molecular studies

Moustafa R. Ali, Haithem A. Farghali, Hala R. Ali, Ahmed H. Osman, Yousef A. Soliman, Yue Wu, Ibrahim M. Ibrahim, Salah A. Selim, Dong M. Shin, Mostafa A. El-Sayed

Cancer Res (2017) 77 (13_Supplement): 175.

https://doi.org/10.1158/1538-7445.AM2017-175

Published: 01 July 2017

View articletitled, Abstract 175: Combination of plasmonic photothermal therapy with surgery applied to naturally occurring mammary tumors in canines and felines: clinical outcomes and molecular studies

Journal Articles

Abstract 187: Efficient delivery of Bcl2 siRNA by DNA nanoparticles to inhibit cellular growth and cancer progression

Mohammad Aminur Rahman, Pengfei Wang, Dongsheng Wang, Selwyn J. Hurwitz, Zhengjia Chen, Zhuo G. Chen, Yonggang Ke, Dong M. Shin

Cancer Res (2017) 77 (13_Supplement): 187.

https://doi.org/10.1158/1538-7445.AM2017-187

Published: 01 July 2017

View articletitled, Abstract 187: Efficient delivery of Bcl2 siRNA by DNA nanoparticles to inhibit cellular growth and cancer progression

Journal Articles

Modulation of Bax and mTOR for Cancer Therapeutics

Cancer Res (2017) 77 (11): 3001–3012.

https://doi.org/10.1158/0008-5472.CAN-16-2356

Published: 31 May 2017

View articletitled, Modulation of Bax and mTOR for Cancer Therapeutics

Includes: Supplementary data

Journal Articles

Abstract 3903: Optimizing the antitumor efficacy of AuNR-assisted plasmonic photothermal therapy and its molecular impact

Mohammad Aminur Rahman, Moustafa R. K. Ali, Zhixiang Zhao, Georgia Z. Chen, Mostafa A. El-Sayed, Dong M. Shin

Cancer Res (2016) 76 (14_Supplement): 3903.

https://doi.org/10.1158/1538-7445.AM2016-3903

Published: 15 July 2016

View articletitled, Abstract 3903: Optimizing the antitumor efficacy of AuNR-assisted plasmonic photothermal therapy and its molecular impact

Journal Articles

Abstract 515: Survivin contributes to radiation resistance in head and neck cancer through regulation of DNA damage repair

Xu Wang, Jonathan J. Beitler, Wen Huang, Guo Chen, Sreenivas Nannapaneni, Nabil F. Saba, Xingming Deng, Zhuo G. Chen, Dong M. Shin

Cancer Res (2016) 76 (14_Supplement): 515.

https://doi.org/10.1158/1538-7445.AM2016-515

Published: 15 July 2016

View articletitled, Abstract 515: Survivin contributes to radiation resistance in head and neck cancer through regulation of DNA damage repair

Journal Articles

Abstract 3502: Combination of BKM120 and erlotinib in squamous cell carcinoma of the head and neck: mechanism of in vitro and in vivo synergy

Abu Anisuzzaman, Abedul Haque, Zhuo Chen, Dong M. Shin, A.R.M. Ruhul Amin.

Cancer Res (2016) 76 (14_Supplement): 3502.

https://doi.org/10.1158/1538-7445.AM2016-3502

Published: 15 July 2016

View articletitled, Abstract 3502: Combination of BKM120 and erlotinib in squamous cell carcinoma of the head and neck: mechanism of in vitro and in vivo synergy

Journal Articles

Abstract 1866: HER3 targeting sensitizes HNSCC to cetuximab - evidence from cell line and patient derived xenograft (PDX) models

Dongsheng Wang, Guoqing Qian, hongzheng zhang, kelly R. Magliocca, sreenivas nannapaneni, zhengjia chen, mihir R. patel, Mark W. El-Deiry, J.trad Wadsworth, dong M. Shin, fadlo R. khuri, Nabil F. Saba, Zhuo G. chen

Cancer Res (2016) 76 (14_Supplement): 1866.

https://doi.org/10.1158/1538-7445.AM2016-1866

Published: 15 July 2016

View articletitled, Abstract 1866: HER3 targeting sensitizes HNSCC to cetuximab - evidence from cell line and patient derived xenograft (PDX) models

Journal Articles

Abstract 3114: Soy isoflavones modulate global methylation in head and neck squamous cell carcinoma (HNSCC)

Laura Rozek, Shama Virani, Emily Bellile, Jeremy Taylor, Maureen Sartor, Alisha Virani, Katie Rentschler, Claire Cote, Francis Worden, Lisa Peterson, Douglas Chepeha, Mark Prince, Scott McLean, George Yoo, Neil F. Saba, Dong M. Shin, Omer Kucuk, Gregory T. Wolf

Cancer Res (2016) 76 (14_Supplement): 3114.

https://doi.org/10.1158/1538-7445.AM2016-3114

Published: 15 July 2016

View articletitled, Abstract 3114: Soy isoflavones modulate global methylation in head and neck squamous cell carcinoma (HNSCC)

Journal Articles

Abstract B15: RSK2 signals through stathmin to promote microtubule dynamics and tumor metastasis

Gina Alesi, Lingtao Jin, Dan Li, Kelly Magliocca, Yibin Kang, Zhuo G. Chen, Dong M. Shin, Fadlo R. Khuri, Sumin Kang

Cancer Res (2016) 76 (7_Supplement): B15.

https://doi.org/10.1158/1538-7445.TUMMET15-B15

Published: 26 May 2016

View articletitled, Abstract B15: RSK2 signals through stathmin to promote microtubule dynamics and tumor metastasis

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Abstract CT037: Early-phase trial of IAP antagonist tolinapant and definitive radiation in cisplatin-ineligible patients with previously untreated, locally advanced head and neck cancer

Abstract 500: Neuropsychological symptoms in patients with head and neck cancer undergoing radiation therapy: A network analysis

Abstract PO-033: Metabolic differences between human papillomavirus-related and smoking-related squamous cell carcinoma of the head and neck independently predict overall patient survival

Abstract 2980: Effects of cetuximab and CD-3379 on cytokine/chemokine balance in the tumor micro-environment (TME) of squamous cell carcinoma of the head and neck (SCCHN)

Abstract 1907: Src-Met signaling confers apoptosis resistance to EGFR and PI3K co-targeting independently of AKT and ERK pathway activation in head and neck cancer

Abstract 4097: TMV vaccine inhibits growth of squamous cell carcinoma of head and neck in mice

Abstract 4834: Effective treatment of squamous cell carcinoma of the head and neck (HNSCC) using a combined regimen of tipifarnib and cetuximab

Abstract 4257: Predicting fatigue levels of head and neck cancer patients with gene expression using machine learning

Abstract 876: Effective reduction of PD-L1 expression by simultaneous blockade of EGFR and HER3 (ErbB3) in head and neck cancer

Abstract 3701: Targeted Bcl2 siRNA delivery using DNA nanoparticles in cancer therapy

Abstract 4110: Combinatory approaches targeting EGFR, HER2 and c-MET in recurrent SCCHN

Abstract 175: Combination of plasmonic photothermal therapy with surgery applied to naturally occurring mammary tumors in canines and felines: clinical outcomes and molecular studies

Abstract 187: Efficient delivery of Bcl2 siRNA by DNA nanoparticles to inhibit cellular growth and cancer progression

Modulation of Bax and mTOR for Cancer Therapeutics

Abstract 3903: Optimizing the antitumor efficacy of AuNR-assisted plasmonic photothermal therapy and its molecular impact

Abstract 515: Survivin contributes to radiation resistance in head and neck cancer through regulation of DNA damage repair

Abstract 3502: Combination of BKM120 and erlotinib in squamous cell carcinoma of the head and neck: mechanism of in vitro and in vivo synergy

Abstract 1866: HER3 targeting sensitizes HNSCC to cetuximab - evidence from cell line and patient derived xenograft (PDX) models

Abstract 3114: Soy isoflavones modulate global methylation in head and neck squamous cell carcinoma (HNSCC)

Abstract B15: RSK2 signals through stathmin to promote microtubule dynamics and tumor metastasis

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