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Donatella Del Bufalo
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Journal Articles

Abstract 1887: Tumor-stroma interactions mediated by Semaphorin 6A as a determinant of drug resistance in BRAF-mut melanoma

Rossella Loria, Italia Falcone, Marta Di Martile, Valentina Caprara, Rocco Fraioli, Valentina Laquintana, Giulia Bon, Laura Rosanò, Donatella Del Bufalo, Ludovica Ciuffreda, Virginia Ferraresi, Michele Milella, Rita Falcioni
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1887.
https://doi.org/10.1158/1538-7445.AM2020-1887
Published: 15 August 2020
View articletitled, Abstract 1887: Tumor-stroma interactions mediated by Semaphorin 6A as a determinant of drug resistance in BRAF-mut melanoma
Journal Articles

Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS–Dependent Pancreatic Ductal Adenocarcinoma

Carla Mottini, Hideo Tomihara, Diego Carrella, Alessia Lamolinara, Manuela Iezzi, Justin K. Huang, Carla A. Amoreo, Simonetta Buglioni, Isabella Manni, Frederick S. Robinson, Rosalba Minelli, Ya'an Kang, Jason B. Fleming, Michael P. Kim, Christopher A. Bristow, Daniela Trisciuoglio, Antonella Iuliano, Donatella Del Bufalo, Diego Di Bernardo, Davide Melisi, Giulio F. Draetta, Gennaro Ciliberto, Alessandro Carugo, Luca Cardone
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (21): 5612–5625.
https://doi.org/10.1158/0008-5472.CAN-19-0187
Published: 01 November 2019
View articletitled, Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS–Dependent Pancreatic Ductal Adenocarcinoma
Open the PDF for Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS–Dependent Pancreatic Ductal Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 768: miR-378a-5p acts as a positive regulator of melanoma progression

Maria Grazia Tupone, Marta Di Martile, Simona D'Aguanno, Elisabetta Valentini, Marianna Desideri, Sara Donzelli, Andrea Sacconi, Daniela Trisciuoglio, Giovanni Blandino, Donatella Del Bufalo
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 768.
https://doi.org/10.1158/1538-7445.AM2019-768
Published: 01 July 2019
View articletitled, Abstract 768: miR-378a-5p acts as a positive regulator of melanoma progression
Journal Articles

Abstract 3699: Histone deacetylase inhibitor ITF2357 induces apoptosis and increases doxorubicin cytotoxicity in preclinical models of human sarcoma

Maria Grazia Tupone, Marta Di Martile, Marianna Desideri, Simonetta Buglioni, Barbara Antoniani, Carlotta Mastroiorio, Rita Falcioni, Virginia Ferraresi, Nicola Baldini, Roberto Biagini, Michele Milella, Daniela Trisciuoglio, Donatella Del Bufalo
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3699.
https://doi.org/10.1158/1538-7445.AM2018-3699
Published: 01 July 2018
View articletitled, Abstract 3699: Histone deacetylase inhibitor ITF2357 induces apoptosis and increases doxorubicin cytotoxicity in preclinical models of human sarcoma
Journal Articles

Abstract 5: The histone acetyltransferase inhibitor CPTH6 impairs tumor angiogenesis acting on both endothelial and cancer cells

Marta Di Martile, Marianna Desideri, Simonetta Buglioni, Carla Azzurra Amoreo, Daniela Trisciuoglio, Donatella Del Bufalo
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5.
https://doi.org/10.1158/1538-7445.AM2018-5
Published: 01 July 2018
View articletitled, Abstract 5: The histone acetyltransferase inhibitor CPTH6 impairs tumor angiogenesis acting on both endothelial and cancer cells
Journal Articles

Abstract 933: Bcl-xL overexpression promotes tumor aggressiveness

Maria Grazia Tupone, Daniela Trisciuoglio, Marianna Desideri, Marta Di Martile, Chiara Gabellini, Simonetta Buglioni, Laura De Salvo, Gabriele Alessandrini, Simona D'Aguanno, Donatella Del Bufalo
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 933.
https://doi.org/10.1158/1538-7445.AM2017-933
Published: 01 July 2017
View articletitled, Abstract 933: Bcl-xL overexpression promotes tumor aggressiveness
Journal Articles

Abstract 4721: Enhancement of doxorubicin cytotoxicity by histone deacetylase inhibition in human sarcoma cells

Maria Grazia Tupone, Daniela Trisciuoglio, Marianna Desideri, Marta Di Martile, Simonetta Buglioni, Barbara Antoniani, Rossella Loria, Rita Falcioni, Michele Milella, Virginia Ferraresi, Gemma Di Pompo, Nicola Baldini, Roberto Biagini, Donatella Del Bufalo
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4721.
https://doi.org/10.1158/1538-7445.AM2016-4721
Published: 15 July 2016
View articletitled, Abstract 4721: Enhancement of doxorubicin cytotoxicity by histone deacetylase inhibition in human sarcoma cells
Journal Articles

Abstract 2324: The histone acetyltransferase inhibitor CPTH6 selectively targets lung cancer stem-like cells

Marta Di Martile, Mariannna Desideri, Teresa De Luca, Chiara Gabellini, Adriana Eramo, Michele Milella, Daniela Secci, Simone Carradori, Simona Buglioni, Donatella Del Bufalo, Daniela Trisciuoglio
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2324.
https://doi.org/10.1158/1538-7445.AM2015-2324
Published: 01 August 2015
View articletitled, Abstract 2324: The histone acetyltransferase inhibitor CPTH6 selectively targets lung cancer stem-like cells
Journal Articles

Abstract 1684: Histone deacetylase inhibition enhances Pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer models

Daniela Trisciuoglio, Marianna Desideri, Teresa D. Luca, Marta D. Martile, Chiara Gabellini, Adriana Eramo, Ruggero D. Maria, Michele Milella, Donatella Del Bufalo
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1684.
https://doi.org/10.1158/1538-7445.AM2014-1684
Published: 01 October 2014
View articletitled, Abstract 1684: Histone deacetylase inhibition enhances Pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer models
Journal Articles

Abstract 2618: PTEN loss as a putative biomarker of synergistic growth inhibitory activity of combined MEK/ERK and PI3K/mTOR pathway blockade

Ludovica Ciuffreda, Italia Falcone, Silvia Matteoni, Andrea Sacconi, Federico Malusa, Teresa D. Luca, Ursula Cesta Incani, Anais Del Curatolo, Marina Konopleva, Michael Andreeff, Adriana Eramo, Ruggero D. Maria, Donatella Del Bufalo, Francesco Cognetti, Michele Milella
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2618.
https://doi.org/10.1158/1538-7445.AM2014-2618
Published: 01 October 2014
View articletitled, Abstract 2618: PTEN loss as a putative biomarker of synergistic growth inhibitory activity of combined MEK/ERK and PI3K/mTOR pathway blockade
Journal Articles

Abstract 77: bcl-xL protein overexpression enhances tumor progression of human melanoma cells in zebrafish xenograft model: Involvement of CXCL8 chemokine

Chiara Gabellini, Elena Gómez, Sofia de Oliveira, Donatella Del Bufalo, Victoriano Mulero
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 77.
https://doi.org/10.1158/1538-7445.AM2014-77
Published: 01 October 2014
View articletitled, Abstract 77: bcl-xL protein overexpression enhances tumor progression of human melanoma cells in zebrafish xenograft model: Involvement of CXCL8 chemokine
Journal Articles

Abstract LB-82: Modulation of autophagic flux by CPTH6, a Gcn5/pCAF histone acetyltransferase inhibitor with antitumoral activity

Chiara Gabellini, Ylenia Ragazzoni, Marianna Desideri, Riccardo Nescatelli, Simone Carradori, Daniela Secci, Daniela Trisciuoglio, Donatella Del Bufalo
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-82.
https://doi.org/10.1158/1538-7445.AM2012-LB-82
Published: 15 April 2012
View articletitled, Abstract LB-82: Modulation of autophagic flux by CPTH6, a Gcn5/pCAF histone acetyltransferase inhibitor with antitumoral activity
Journal Articles

Abstract 16: Involvement of BH4 domain of bcl-2 in the regulation of HIF-1-mediated VEGF expression in hypoxic tumor cells

Chiara Gabellini, Daniela Trisciuoglio, Marianna desideri, Ylenia Ragazzoni, Teresa De Luca, Donatella Del Bufalo
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 16.
https://doi.org/10.1158/1538-7445.AM2011-16
Published: 15 April 2011
View articletitled, Abstract 16: Involvement of BH4 domain of bcl-2 in the regulation of HIF-1-mediated VEGF expression in hypoxic tumor cells
Journal Articles

Antiangiogenic Potential of the Mammalian Target of Rapamycin Inhibitor Temsirolimus

Donatella Del Bufalo, Ludovica Ciuffreda, Daniela Trisciuoglio, Marianna Desideri, Francesco Cognetti, Gabriella Zupi, Michele Milella
Journal: Cancer Research
Cancer Res (2006) 66 (11): 5549–5554.
https://doi.org/10.1158/0008-5472.CAN-05-2825
Published: 01 June 2006
View articletitled, Antiangiogenic Potential of the Mammalian Target of Rapamycin Inhibitor Temsirolimus
Open the PDF for Antiangiogenic Potential of the Mammalian Target of Rapamycin Inhibitor Temsirolimus in another window
Journal Articles

Blockade of mTOR signaling by Temsirolimus inhibits angiogenesis through direct and indirect mechanisms.

Donatella Del Bufalo, Ludovica Ciuffreda, Daniela Trisciuoglio, Francesco Cognetti, Gabriella Zupi, Michele Milella
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 105.
Published: 01 May 2005
View articletitled, Blockade of mTOR signaling by Temsirolimus inhibits angiogenesis through direct and indirect mechanisms.