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Donald M. Miller
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Journal Articles

Abstract 1522: Targeted gene therapy · c-MYC and hTERT in the scope

Francine Rezzoug, Shelia D. Thomas, Segen Tella, Donald M. Miller
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1522.
https://doi.org/10.1158/1538-7445.AM2017-1522
Published: 01 July 2017
View articletitled, Abstract 1522: Targeted gene therapy · c-MYC and hTERT in the scope
Journal Articles

Abstract 1521: hTERT G-quadruplex-targeted oligonucleotides inhibit glioblastoma cell growth

Alex West, Francine Rezzoug, Shelia D. Thomas, Donald M. Miller
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1521.
https://doi.org/10.1158/1538-7445.AM2017-1521
Published: 01 July 2017
View articletitled, Abstract 1521: hTERT G-quadruplex-targeted oligonucleotides inhibit glioblastoma cell growth
Journal Articles

Abstract 5418: Lipid modification of c-MYC promoter targeted oligonucleotide stabilizes G-quadruplex formation and enhances its growth inhibitory activity in leukemia cells

Francine Francine, Shelia D. Thomas, Gilles Tapolsky, Donald M. Miller
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5418.
https://doi.org/10.1158/1538-7445.AM2015-5418
Published: 01 August 2015
View articletitled, Abstract 5418: Lipid modification of c-MYC promoter targeted oligonucleotide stabilizes G-quadruplex formation and enhances its growth inhibitory activity in leukemia cells
Journal Articles

Abstract PR02: Specific inhibition of hTERT expression in melanoma by targeting common promoter mutations which cause quadruplex DNA instability

Donald M. Miller, Alexandra Sokolova, Francine Rezzoug, Shelia Thomas, Jonathan Chaires, Jonathan Chaires, William Dean, John Trent
Journal: Cancer Research
Cancer Res (2015) 75 (14_Supplement): PR02.
https://doi.org/10.1158/1538-7445.MEL2014-PR02
Published: 16 July 2015
View articletitled, Abstract PR02: Specific inhibition of hTERT expression in melanoma by targeting common promoter mutations which cause quadruplex DNA instability
Journal Articles

Abstract 2607: G-rich DNA genomic sequences derived from the promoter region of pro-oncogenes selectively inhibit tumor growth and demonstrate strong synergies

Gilles H. Tapolsky, Kara Sedoris, Shelia Thomas, Francine Rezzoug, Donald M. Miller
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2607.
https://doi.org/10.1158/1538-7445.AM2014-2607
Published: 01 October 2014
View articletitled, Abstract 2607: G-rich DNA genomic sequences derived from the promoter region of pro-oncogenes selectively inhibit tumor growth and demonstrate strong synergies
Journal Articles

Abstract 5101: Common mutations in the hTERT promoter cause instability in quadruplex DNA which is overcome by quadruplex stabilizing agents and targeted oligonucleotides

Alexandra Sokolova, Shelia Thomas, Francine Rezzoug, Johnathan Chaires, William Dean, Robert Buscaglia, Donald M. Miller
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5101.
https://doi.org/10.1158/1538-7445.AM2014-5101
Published: 01 October 2014
View articletitled, Abstract 5101: Common mutations in the hTERT promoter cause instability in quadruplex DNA which is overcome by quadruplex stabilizing agents and targeted oligonucleotides
Journal Articles

Abstract 3811: G-quadruplex-forming genomic sequences homologous to Pu27 interact with c-Myc promoter and regulate c-Myc transcription

Francine Rezzoug, Shelia D. Thomas, Eric C. Rouchka, Donald M. Miller
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3811.
https://doi.org/10.1158/1538-7445.AM2014-3811
Published: 01 October 2014
View articletitled, Abstract 3811: G-quadruplex-forming genomic sequences homologous to Pu27 interact with c-Myc promoter and regulate c-Myc transcription
Journal Articles

Abstract 743: Pu-27 G-quadruplex induces uncompensated DNA damage response by destabilizing shelterin complex at telomere and non-telomeric region leading to cell death.

Md Ashraful Islam, Shelia D. Thomas, Kara J. Sedoris, Donald M. Miller
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 743.
https://doi.org/10.1158/1538-7445.AM2013-743
Published: 15 April 2013
View articletitled, Abstract 743: Pu-27 G-quadruplex induces uncompensated DNA damage response by destabilizing shelterin complex at telomere and non-telomeric region leading to cell death.
Journal Articles

Abstract 5193: The importance of primo vascular system (PVS) on cancer metastasis and therapeutic intervention: A new dimension of cancer stem cell

Ashraful Islam, Shelia D. Thomas, Kara J. Sedoris, Donald M. Miller
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5193.
https://doi.org/10.1158/1538-7445.AM2012-5193
Published: 15 April 2012
View articletitled, Abstract 5193: The importance of primo vascular system (PVS) on cancer metastasis and therapeutic intervention: A new dimension of cancer stem cell
Journal Articles

Abstract 2123: ATM mediated homeostasis of ‘shelterin’ at telomere is compromised by G-quadruplex leading to DNA damage

Ashraful Islam, Shelia D. Thomas, Kara J. Sedoris, Donald M. Miller
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2123.
https://doi.org/10.1158/1538-7445.AM2012-2123
Published: 15 April 2012
View articletitled, Abstract 2123: ATM mediated homeostasis of ‘shelterin’ at telomere is compromised by G-quadruplex leading to DNA damage
Journal Articles

Abstract 3: Induction of mitochondrial autophagy in leukemia by the Bcl-2 quadruplex-forming sequence

Kara C. Sedoris, Cortney R. Clarkson, Shelia D. Thomas, Donald M. Miller
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3.
https://doi.org/10.1158/1538-7445.AM2011-3
Published: 15 April 2011
View articletitled, Abstract 3: Induction of mitochondrial autophagy in leukemia by the Bcl-2 quadruplex-forming sequence
Journal Articles

Abstract 4996: The VEGF quadruplex-forming sequence inhibits lung cancer cell growth

David Muench, Shelia D. Thomas, Donald M. Miller, Kara C. Sedoris
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4996.
https://doi.org/10.1158/1538-7445.AM2011-4996
Published: 15 April 2011
View articletitled, Abstract 4996: The VEGF quadruplex-forming sequence inhibits lung cancer cell growth
Journal Articles

Abstract 3886: The G-quadruplex induced DNA damage at telomeres is regulated by ATM

Ashraful Islam, Shelia D. Thoma, Donald M. Miller
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3886.
https://doi.org/10.1158/1538-7445.AM2011-3886
Published: 15 April 2011
View articletitled, Abstract 3886: The G-quadruplex induced DNA damage at telomeres is regulated by ATM
Journal Articles

Abstract 1024: Selective inhibition of bcl-2 gene expression and leukemic cell growth by the bcl-2 quadruplex-forming sequence

Kara Sedoris, Shelia D. Thomas, Divyansh Sharma, Campbell Grant, Cortney R. Clarkson, Donald M. Miller
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1024.
https://doi.org/10.1158/1538-7445.AM10-1024
Published: 15 April 2010
View articletitled, Abstract 1024: Selective inhibition of bcl-2 gene expression and leukemic cell growth by the bcl-2 quadruplex-forming sequence
Journal Articles

Abstract 2949: The VEGF quadruplex-forming sequence inhibits cell growth of lung cancer

Shelia D. Thomas, Campbell M. Grant, Cortney R. Clarkson, Donald M. Miller, Kara C. Sedoris
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2949.
https://doi.org/10.1158/1538-7445.AM10-2949
Published: 15 April 2010
View articletitled, Abstract 2949: The VEGF quadruplex-forming sequence inhibits cell growth of lung cancer
Journal Articles

Pre-clinical efficacy, pharmacokinetic, and toxicity studies of AGRO100, an anti-tumor oligonucleotide aptamer.

Kerry M. Barnhart, Paula J. Bates, John O. Trent, Xiaohua Xu, Shelia Thomas, Donald M. Miller
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 876.
Published: 01 April 2004
View articletitled, Pre-clinical efficacy, pharmacokinetic, and toxicity studies of AGRO100, an anti-tumor oligonucleotide aptamer.
Journal Articles

Phase I Trial of the Murine Monoclonal Anti-GD2 Antibody 14G2a in Metastatic Melanoma

Mansoor N. Saleh, M. B. Khazaeli, Richard H. Wheeler, Edward Dropcho, Tiepu Liu, Marshall Urist, Donald M. Miller, Sharon Lawson, Pam Dixon, Charles H. Russell, Albert F. LoBuglio
Journal: Cancer Research
Cancer Res (1992) 52 (16): 4342–4347.
Published: 01 August 1992
View articletitled, Phase I Trial of the Murine Monoclonal Anti-GD2 Antibody 14G2a in Metastatic Melanoma
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