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Abstract LB250: Development of organoid raft cultures of cervical, breast and glioblastoma tumors as quick economical ex vivo human cancer models for pre-clinical drug evaluation

Nilam Sanjib Banerjee, Dianne W. Moore, Abhisek Gangrade, Donald J. Buchsbaum, Luise Burt Nabors, Thomas R. Broker, Louise T. Chow

Cancer Res (2021) 81 (13_Supplement): LB250.

DOI: https://doi.org/10.1158/1538-7445.AM2021-LB250

Published: 01 July 2021

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Journal Articles

STAT3 and GR Cooperate to Drive Gene Expression and Growth of Basal-Like Triple-Negative Breast Cancer

Megan E. Conway, Joy M. McDaniel, James M. Graham, Katrin P. Guillen, Patsy G. Oliver, Stephanie L. Parker, Peibin Yue, James Turkson, Donald J. Buchsbaum, Bryan E. Welm, Richard M. Myers, Katherine E. Varley

Cancer Res (2020) 80 (20): 4355–4370.

DOI: https://doi.org/10.1158/0008-5472.CAN-20-1379

Published: 15 October 2020

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Includes: Supplementary data

Journal Articles

Abstract 4710: The effect of Wnt inhibition combined with paclitaxel on tumor burden and CD8+ T cell infiltration in syngeneic murine models of ovarian cancer

David W. Doo, Angelina I. Londono, Dylana J. Moore, Selene Meza-Perez, Ashwini A. Katre, Tyler R. McCaw, Haller J. Smith, Carol Y. Lin, Sara J. Cooper, J Michael Straughn, Donald J. Buchsbaum, Lyse A. Norian, Troy D. Randall, Rebecca C. Arend

Cancer Res (2018) 78 (13_Supplement): 4710.

DOI: https://doi.org/10.1158/1538-7445.AM2018-4710

Published: 01 July 2018

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Journal Articles

Abstract 4700: Manipulating the breast tumor microenvironment with histone deacetylase inhibitors for more robust and durable T cell responses

Tyler R. McCaw, Mingyong Liu, Mei Li, Dmytro Starenki, Sara J. Cooper, Rebecca C. Arend, Andres Forero, Donald J. Buchsbaum, Troy D. Randall

Cancer Res (2018) 78 (13_Supplement): 4700.

DOI: https://doi.org/10.1158/1538-7445.AM2018-4700

Published: 01 July 2018

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Journal Articles

Abstract 643: Induced MHCII expression on breast cancer cells broadens the responding T cell repertoire, delays tumor-specific T cell exhaustion, and impairs tumor growth

Tyler R. McCaw, Mei Li, Selene Meza-Perez, Donald J. Buchsbaum, Dmytro Starenki, Sara Cooper, Andres Forero, Troy D. Randall

Cancer Res (2017) 77 (13_Supplement): 643.

DOI: https://doi.org/10.1158/1538-7445.AM2017-643

Published: 01 July 2017

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Journal Articles

Abstract 5173: Discovery of a series of benzimidazoles as potent Wnt/β-catenin signaling inhibitors in colorectal cancer cells

Yonghe Li, Patsy G. Oliver, Wenyan Lu, Vibha Pathak, Corinne E. Augelli-Szafran, Donald J. Buchsbaum, Mark J. Suto

Cancer Res (2017) 77 (13_Supplement): 5173.

DOI: https://doi.org/10.1158/1538-7445.AM2017-5173

Published: 01 July 2017

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Journal Articles

Abstract 1461: MHCII-expressing breast cancer cells can induce anti-tumor immune response

Mei Li, Tyler R. McCaw, Selene Meza-Perez, Troy D. Randall, Amy Weinmann, Donald J. Buchsbaum, Andres Forero, Albert F. LoBuglio

Cancer Res (2016) 76 (14_Supplement): 1461.

DOI: https://doi.org/10.1158/1538-7445.AM2016-1461

Published: 15 July 2016

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Journal Articles

Abstract 3327: The tumor associated sialyltransferase ST6Gal-I promotes a cancer stem cell phenotype and upregulates stem-related transcription factors

Matthew J. Schultz, Andrew T. Holdbrooks, Asmi Chakraborty, William E. Grizzle, Charles N. Landen, Donald J. Buchsbaum, Michael G. Conner, Rebecca C. Arend, Karina J. Yoon, Chris A. Klug, Daniel C. Bullard, Robert A. Kesterson, Patsy G. Oliver, Amber K. O’Connor, Bradley K. Yoder, Susan L. Bellis

Cancer Res (2016) 76 (14_Supplement): 3327.

DOI: https://doi.org/10.1158/1538-7445.AM2016-3327

Published: 15 July 2016

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Journal Articles

Abstract 4030: Epigenetic induction of MHC-II pathway expression in murine ovarian cancer cell line

Taylor B. Turner, Rebecca C. Arend, Mei Li, Troy D. Randall, Andres Forero-Torres, Albert F. LoBuglio, J Michael Straughn, Donald J. Buchsbaum

Cancer Res (2016) 76 (14_Supplement): 4030.

DOI: https://doi.org/10.1158/1538-7445.AM2016-4030

Published: 15 July 2016

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Journal Articles

The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell Phenotype

Matthew J. Schultz, Andrew T. Holdbrooks, Asmi Chakraborty, William E. Grizzle, Charles N. Landen, Donald J. Buchsbaum, Michael G. Conner, Rebecca C. Arend, Karina J. Yoon, Christopher A. Klug, Daniel C. Bullard, Robert A. Kesterson, Patsy G. Oliver, Amber K. O'Connor, Bradley K. Yoder, Susan L. Bellis

Cancer Res (2016) 76 (13): 3978–3988.

DOI: https://doi.org/10.1158/0008-5472.CAN-15-2834

Published: 30 June 2016

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Journal Articles

Abstract 2931: Calmodulin-DR5 binding in breast cancer: Independent of TRA-8 sensitivity

Romone M. Fancy, Donald J. Buchsbaum, Tong Zhou, Yuhua Song

Cancer Res (2015) 75 (15_Supplement): 2931.

DOI: https://doi.org/10.1158/1538-7445.AM2015-2931

Published: 01 August 2015

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Journal Articles

Abstract A100: Role of HER3 ligand-independent activation in EGFR resistance in pancreatic cancer

Donald J. Buchsbaum, Tong Zhou

Cancer Res (2015) 75 (13_Supplement): A100.

DOI: https://doi.org/10.1158/1538-7445.PANCA2014-A100

Published: 30 June 2015

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Journal Articles

Abstract 2517: STAT3 inhibition by LLL12 in combination with niclosamide and chemotherapy in ovarian cancer

Rebecca C. Arend, Christen L. Walters Haygood, Chandrika Kurpad, Abhishek Gangrade, Pui-Kai Li, Yonghi Li, Deepak Bhasin, J. Michael Straughn, Donald J. Buchsbaum

Cancer Res (2014) 74 (19_Supplement): 2517.

DOI: https://doi.org/10.1158/1538-7445.AM2014-2517

Published: 01 October 2014

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Journal Articles

Abstract A25: Novel anti-HER3 strategy for pancreatic cancer therapy.

Donald J. Buchsbaum, Xian Chen, Enyun Shen, Tong Zhou

Cancer Res (2012) 72 (14_Supplement): A25.

DOI: https://doi.org/10.1158/1538-7445.PANCA2012-A25

Published: 03 April 2014

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Journal Articles

Abstract 865: Inhibition of Wnt co-receptor LRP6 sensitizes basal-like breast cancer stem cells to TRA-8 anti-DR5 monoclonal antibody.

Angelina I. Londono-Joshi, Rebecca C. Arend, Laura Aristizabal, Yonghe Li, Wenyan Lu, Rajeev S. Samant, Brandon J. Metge, Andres Forero, Tong Zhou, Albert F. LoBuglio, Donald J. Buchsbaum

Cancer Res (2013) 73 (8_Supplement): 865.

DOI: https://doi.org/10.1158/1538-7445.AM2013-865

Published: 15 April 2013

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Journal Articles

Abstract 4013: S100A4 promotes cell migration and growth through focal adhesion kinase and Src mediated dual signaling pathways in pancreatic cancer cells.

Guoqiang Cai, Elizabeth H. Kerr, Meng Hu, Youfeng Yang, Donald J. Buchsbaum, William E. Grizzle, Qiang Ding

Cancer Res (2013) 73 (8_Supplement): 4013.

DOI: https://doi.org/10.1158/1538-7445.AM2013-4013

Published: 15 April 2013

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Journal Articles

Abstract 2179: Wnt pathway inhibition by niclosamide: a therapeutic target for ovarian cancer.

Rebecca C. Arend, Angelina I. Londoño-Joshi, Yonghe Li, Wenyan Lu, Rajeev S. Samant, Brandon J. Metge, J. Michael Straughn, Donald J. Buchsbaum

Cancer Res (2013) 73 (8_Supplement): 2179.

DOI: https://doi.org/10.1158/1538-7445.AM2013-2179

Published: 15 April 2013

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Journal Articles

ST6Gal-I Protein Expression Is Upregulated in Human Epithelial Tumors and Correlates with Stem Cell Markers in Normal Tissues and Colon Cancer Cell Lines

Amanda F. Swindall, Angelina I. Londoño-Joshi, Matthew J. Schultz, Naomi Fineberg, Donald J. Buchsbaum, Susan L. Bellis

Cancer Res (2013) 73 (7): 2368–2378.

DOI: https://doi.org/10.1158/0008-5472.CAN-12-3424

Published: 02 April 2013

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Includes: Supplementary data

Journal Articles

Abstract 1714: Chemoresistance in patients with papillary serous carcinoma of the ovary

Elizabeth H. Kerr, Peter J. Frederick, Denise K. Oelschlager, Hope Amm, Jeffery Sellers, Debbie Della Manna, Donald J. Buchsbaum, William E. Grizzle, Lacey R. McNally

Cancer Res (2011) 71 (8_Supplement): 1714.

DOI: https://doi.org/10.1158/1538-7445.AM2011-1714

Published: 15 April 2011

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Journal Articles

Abstract 181: The combination of a novel retinoid compound with standard chemotherapy increases cytotoxicity in an ovarian cancer cell line

Jenny M. Whitworth, Patsy J. Oliver, Donald D. Muccio, J. Michael Straughn, Donald J. Buchsbaum

Cancer Res (2011) 71 (8_Supplement): 181.

DOI: https://doi.org/10.1158/1538-7445.AM2011-181

Published: 15 April 2011

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NARROW

Abstract LB250: Development of organoid raft cultures of cervical, breast and glioblastoma tumors as quick economical ex vivo human cancer models for pre-clinical drug evaluation

STAT3 and GR Cooperate to Drive Gene Expression and Growth of Basal-Like Triple-Negative Breast Cancer

Abstract 4710: The effect of Wnt inhibition combined with paclitaxel on tumor burden and CD8+ T cell infiltration in syngeneic murine models of ovarian cancer

Abstract 4700: Manipulating the breast tumor microenvironment with histone deacetylase inhibitors for more robust and durable T cell responses

Abstract 643: Induced MHCII expression on breast cancer cells broadens the responding T cell repertoire, delays tumor-specific T cell exhaustion, and impairs tumor growth

Abstract 5173: Discovery of a series of benzimidazoles as potent Wnt/β-catenin signaling inhibitors in colorectal cancer cells

Abstract 1461: MHCII-expressing breast cancer cells can induce anti-tumor immune response

Abstract 3327: The tumor associated sialyltransferase ST6Gal-I promotes a cancer stem cell phenotype and upregulates stem-related transcription factors

Abstract 4030: Epigenetic induction of MHC-II pathway expression in murine ovarian cancer cell line

The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell Phenotype

Abstract 2931: Calmodulin-DR5 binding in breast cancer: Independent of TRA-8 sensitivity

Abstract A100: Role of HER3 ligand-independent activation in EGFR resistance in pancreatic cancer

Abstract 2517: STAT3 inhibition by LLL12 in combination with niclosamide and chemotherapy in ovarian cancer

Abstract A25: Novel anti-HER3 strategy for pancreatic cancer therapy.

Abstract 865: Inhibition of Wnt co-receptor LRP6 sensitizes basal-like breast cancer stem cells to TRA-8 anti-DR5 monoclonal antibody.

Abstract 4013: S100A4 promotes cell migration and growth through focal adhesion kinase and Src mediated dual signaling pathways in pancreatic cancer cells.

Abstract 2179: Wnt pathway inhibition by niclosamide: a therapeutic target for ovarian cancer.

ST6Gal-I Protein Expression Is Upregulated in Human Epithelial Tumors and Correlates with Stem Cell Markers in Normal Tissues and Colon Cancer Cell Lines

Abstract 1714: Chemoresistance in patients with papillary serous carcinoma of the ovary

Abstract 181: The combination of a novel retinoid compound with standard chemotherapy increases cytotoxicity in an ovarian cancer cell line

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