1-20 of 26
Dominic Esposito
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract 2272: Interrogating RAS isoform and mutational specificity for effectors with bioluminescence resonance energy transfer (BRET)

Megan Rigby, John Columbus, Vanessa Wall, Dominic Esposito, Thomas Turbyville
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2272.
https://doi.org/10.1158/1538-7445.AM2021-2272
Published: 01 July 2021
View article titled, Abstract 2272: Interrogating RAS isoform and mutational specificity for effectors with bioluminescence resonance energy transfer (BRET)
Journal Articles

Abstract 5133: Optimized RAS top-down proteomic assay reveals expanded proteoform landscape in malignant cells

Caroline DeHart, Kanika Sharma, Dominic Esposito, Anna Maciag, Dwight Nissley, Frank McCormick
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5133.
https://doi.org/10.1158/1538-7445.AM2020-5133
Published: 15 August 2020
View article titled, Abstract 5133: Optimized RAS top-down proteomic assay reveals expanded proteoform landscape in malignant cells
Journal Articles

Abstract 372: Macrophage contact-dependent stemness induction and progressive CSC enrichment during metastatic dissemination in breast cancer

Ved P. Sharma, Yarong Wang, Binwu Tang, George S. Karagiannis, Emily A. Xue, David Entenberg, Lucia Borriello, Anouchka Coste, Joan G. Jones, Chinmay R. Surve, Dominic Esposito, Maja H. Oktay, Lalage M. Wakefield, John S. Condeelis
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 372.
https://doi.org/10.1158/1538-7445.AM2020-372
Published: 15 August 2020
View article titled, Abstract 372: Macrophage contact-dependent stemness induction and progressive CSC enrichment during metastatic dissemination in breast cancer
Journal Articles

Abstract 2586: Identification of cancer-associated RhoA mutants and analogous K-Ras mutants that induce gain-of function despite low GTP binding

Xiaolan Qian, Alex Papageorge, Dunrui Wang, Brajendra Tripathi, Yucheng Gao, Marian Durkin, Beatriz Sanchez-Solana, Dominic Esposito, Timothy Waybright, Andrew Stephen, Douglas R. Lowy
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2586.
https://doi.org/10.1158/1538-7445.AM2020-2586
Published: 15 August 2020
View article titled, Abstract 2586: Identification of cancer-associated RhoA mutants and analogous K-Ras mutants that induce gain-of function despite low GTP binding
Journal Articles

Abstract LB-062: A live-cell, protein-protein interaction assay identified inhibitors of KRAS4b-G12D interaction with full-length RAF1

John Columbus, Thomas J. Turbyville, Vanessa Wall, Dominic Esposito, David A. Barda, Sheng-Bin Peng
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): LB-062.
https://doi.org/10.1158/1538-7445.AM2020-LB-062
Published: 15 August 2020
View article titled, Abstract LB-062: A live-cell, protein-protein interaction assay identified inhibitors of KRAS4b-G12D interaction with full-length RAF1
Journal Articles

Abstract 1768: Biochemical and structural analysis of the Neurofibromin (NF1) protein and a potential role for protein destabilization in Rasopathy diseases

Mukul Sherekar, Sae-Won Han, Simon Messing, Matthew Drew, William Gillette, Claire Lorenzo, Frank McCormick, Dominic Esposito
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1768.
https://doi.org/10.1158/1538-7445.AM2019-1768
Published: 01 July 2019
View article titled, Abstract 1768: Biochemical and structural analysis of the Neurofibromin (NF1) protein and a potential role for protein destabilization in Rasopathy diseases
Journal Articles

Abstract 972: Direct observation in living tumors shows macrophage-dependent induction and dissemination of cancer stem cells in breast cancer

Ved P. Sharma, Yarong Wang, Binwu Tang, George S. Karagiannis, Emily A. Xue, David Entenberg, Lucia Borriello, Anouchka Coste, Chinmay R. Surve, Dominic Esposito, Maja H. Oktay, Lalage M. Wakefield, John S. Condeelis
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 972.
https://doi.org/10.1158/1538-7445.AM2019-972
Published: 01 July 2019
View article titled, Abstract 972: Direct observation in living tumors shows macrophage-dependent induction and dissemination of cancer stem cells in breast cancer
Journal Articles

Abstract 960: Structures of oncogenic KRAS mutants in the active state and complexed with RasGAP provide new insights into targeting RAS-driven cancer

Timothy Tran, Srisathiyanarayanan Dharmaiah, Wupeng Yan, Albert Chan, Timothy Waybright, William Gillette, Dominic Esposito, Andrew Stephen, Dwight Nissley, Frank McCormick, Dhirendra K. Simanshu
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 960.
https://doi.org/10.1158/1538-7445.AM2019-960
Published: 01 July 2019
View article titled, Abstract 960: Structures of oncogenic KRAS mutants in the active state and complexed with RasGAP provide new insights into targeting RAS-driven cancer
Journal Articles

Abstract 4920: Intratumoral levels of BAX-BAK heterodimer as a specific on-target pharmacodynamic biomarker of drug action by novel BH3 mimetics

Apurva K. Srivastava, Jeevan P. Govindharajulu, Dominic Esposito, Melinda G. Hollingshead, James H. Doroshow, Ralph E. Parchment
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4920.
https://doi.org/10.1158/1538-7445.AM2018-4920
Published: 01 July 2018
View article titled, Abstract 4920: Intratumoral levels of BAX-BAK heterodimer as a specific on-target pharmacodynamic biomarker of drug action by novel BH3 mimetics
Journal Articles

Abstract 1369: DNA, protein, and cell line reagents to facilitate RAS pathway drug discovery efforts

Dominic Esposito
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1369.
https://doi.org/10.1158/1538-7445.AM2017-1369
Published: 01 July 2017
View article titled, Abstract 1369: DNA, protein, and cell line reagents to facilitate RAS pathway drug discovery efforts
Journal Articles

Abstract 1366: Structural basis of impaired GTP hydrolysis in oncogenic mutants of KRAS

Timothy Tran, Sathiya Dharmaiah, Oleg Chertov, Timothy Waybright, William Gillette, Dominic Esposito, Dwight Nissley, Frank McCormick, Andrew Stephen, Dhirendra Simanshu
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1366.
https://doi.org/10.1158/1538-7445.AM2017-1366
Published: 01 July 2017
View article titled, Abstract 1366: Structural basis of impaired GTP hydrolysis in oncogenic mutants of KRAS
Journal Articles

Abstract 5238: Structural and biochemical characterization of membrane bound KRAS

Andrew G. Stephen, Que Van, Marco Tonelli, William Gillette, Dominic Esposito, Ben Niu, Michael Gross, Frank Heinrich, Arvind Ramanathan, Christopher Stanley
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5238.
https://doi.org/10.1158/1538-7445.AM2017-5238
Published: 01 July 2017
View article titled, Abstract 5238: Structural and biochemical characterization of membrane bound KRAS
Journal Articles

Abstract 4373: Structural basis of recognition of farnesylated and methylated KRAS4b by PDEδ

Sathiya Dharmaiah, Lakshman Bindu, Peter Frank, William Gillette, Dominic Esposito, Dwight Nissley, Frank McCormick, Andrew Stephen, Dhirendra Simanshu
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4373.
https://doi.org/10.1158/1538-7445.AM2016-4373
Published: 15 July 2016
View article titled, Abstract 4373: Structural basis of recognition of farnesylated and methylated KRAS4b by PDEδ
Journal Articles

Abstract 1872: Development of reference reagents to accelerate research on the RAS pathway

Dominic Esposito, Jennifer Mehalko, Vanessa Wall, Carissa Grose, William Gillette, Robert Stephens
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1872.
https://doi.org/10.1158/1538-7445.AM2016-1872
Published: 15 July 2016
View article titled, Abstract 1872: Development of reference reagents to accelerate research on the RAS pathway
Journal Articles

Abstract 1879: Structural and biochemical characterization of farnesylated and methylated KRAS-membrane interactions

Que Van, William K. Gillette, Dominic Esposito, Rodolfo Ghirlando, Frank Heinrich, Andrew G. Stephen
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1879.
https://doi.org/10.1158/1538-7445.AM2016-1879
Published: 15 July 2016
View article titled, Abstract 1879: Structural and biochemical characterization of farnesylated and methylated KRAS-membrane interactions
Journal Articles

Abstract 3925: Production and biochemical characterization of farnesylated and methylated KRAS4b using engineered baculovirus

Andrew G. Stephen, William K. Gillette, Carissa Grose, Dominic Esposito
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3925.
https://doi.org/10.1158/1538-7445.AM2015-3925
Published: 01 August 2015
View article titled, Abstract 3925: Production and biochemical characterization of farnesylated and methylated KRAS4b using engineered baculovirus
Journal Articles

Abstract 2151: Development of reference reagents to accelerate research on the RAS pathway

Dominic Esposito
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2151.
https://doi.org/10.1158/1538-7445.AM2015-2151
Published: 01 August 2015
View article titled, Abstract 2151: Development of reference reagents to accelerate research on the RAS pathway
Journal Articles

Abstract 2221: Transforming Growth Factor-beta (TGF-β) directly regulates breast cancer stem cell dynamics in vitro and in vivo

Binwu Tang, Asaf Raviv, Dominic Esposito, Catherine Daniel, Kathleen C. Flanders, Yu-an Yang, Lalage M. Wakefield
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2221.
https://doi.org/10.1158/1538-7445.AM2015-2221
Published: 01 August 2015
View article titled, Abstract 2221: Transforming Growth Factor-beta (TGF-β) directly regulates breast cancer stem cell dynamics in vitro and in vivo
Journal Articles

Abstract B45: A novel reporter system with potential for in situ assessment of tumor microenvironmental effects on cancer stem cells

Binwu Tang, Asaf Raviv, Dominic Esposito, Catherine Daniel, Bao Tram Nghiem, Susan Garfield, Langston Lim, Poonam Mannan, Ana Robles, William Smith, Joshua Zimmerberg, Rea Ravin, Lalage Wakefield
Journal: Cancer Research
Cancer Res (2015) 75 (1_Supplement): B45.
https://doi.org/10.1158/1538-7445.CHTME14-B45
Published: 12 January 2015
View article titled, Abstract B45: A novel reporter system with potential for in situ assessment of tumor microenvironmental effects on cancer stem cells
Journal Articles

Abstract C23: MicroRNA-106b targets caspase-7 and is associated with recurrence in human prostate cancer

Robert S. Hudson, Tiffany H. Dorsey, Ming Yi, Dominic Esposito, Robert M. Stephens, Carlo M. Croce, Stefan Ambs
Journal: Cancer Research
Cancer Res (2012) 72 (4_Supplement): C23.
https://doi.org/10.1158/1538-7445.PRCA2012-C23
Published: 09 May 2013
View article titled, Abstract C23: MicroRNA-106b targets caspase-7 and is associated with recurrence in human prostate cancer