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Dominic A. Scudiero
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Journal Articles

Abstract 1621: The proprotein convertase PCSK1 is a novel drug target in alveolar soft part sarcoma (ASPS)

David T. Vistica, Susan Kenney, Dominic A. Scudiero, Russell A. Reinhart, Michael H. Selby, Donna O. Butcher, Robert H. Shoemaker
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1621.
https://doi.org/10.1158/1538-7445.AM2011-1621
Published: 15 April 2011
View article titled, Abstract 1621: The proprotein convertase PCSK1 is a novel drug target in alveolar soft part sarcoma (ASPS)
Journal Articles

Abstract 5202: Human colon cancer cell lines contain subsets of cells with the capacity to initiate highly prolific clonal growth in soft agar culture and to form transplantable tumor xenografts in vivo

Michael C. Alley, Melinda G. Hollingshead, Suzanne D. Borgel, Kevin Plater, Mark W. Burkett, Miriam R. Anver, Brandon R. Yen, Karen M. Hite, Dominic A. Scudiero, Anne Monks, Susan D. Mertins, Robert H. Shoemaker, John E. Niederhuber
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5202.
https://doi.org/10.1158/1538-7445.AM2011-5202
Published: 15 April 2011
View article titled, Abstract 5202: Human colon cancer cell lines contain subsets of cells with the capacity to initiate highly prolific clonal growth in soft agar culture and to form transplantable tumor xenografts <em>in vivo</em>
Journal Articles

Abstract 3372: Analysis of putative tumor stem cell markers in the NCI-60 tumor cell line panel

Christina H. Stuelten, Susan D. Mertins, Johanna I. Busch, Meghan Gowens, Dominic A. Scudiero, Mark W. Burkett, Karen Hite, Michael Alley, Melinda Hollingshead, Robert H. Shoemaker, John E. Niederhuber
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3372.
https://doi.org/10.1158/1538-7445.AM10-3372
Published: 15 April 2010
View article titled, Abstract 3372: Analysis of putative tumor stem cell markers in the NCI-60 tumor cell line panel
Journal Articles

Integrating Global Gene Expression and Radiation Survival Parameters across the 60 Cell Lines of the National Cancer Institute Anticancer Drug Screen

Sally A. Amundson, Khanh T. Do, Lisa C. Vinikoor, R. Anthony Lee, Christine A. Koch-Paiz, Jaeyong Ahn, Mark Reimers, Yidong Chen, Dominic A. Scudiero, John N. Weinstein, Jeffrey M. Trent, Michael L. Bittner, Paul S. Meltzer, Albert J. Fornace, Jr.
Journal: Cancer Research
Cancer Res (2008) 68 (2): 415–424.
https://doi.org/10.1158/0008-5472.CAN-07-2120
Published: 15 January 2008
View article titled, Integrating Global Gene Expression and Radiation Survival Parameters across the 60 Cell Lines of the National Cancer Institute Anticancer Drug Screen
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Includes: Supplementary data
Journal Articles

NSC13778 disrupts interactions between transcription factors TFE3, ASPL-TFE3 type 1, and ASPL-TFE3 type 2 and cognate DNA

Paula M. Krosky, Susan Kenney, David T. Vistica, Dominic A. Scudiero, Robert H. Shoemaker
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1086.
Published: 15 April 2006
View article titled, NSC13778 disrupts interactions between transcription factors TFE3, ASPL-TFE3 type 1, and ASPL-TFE3 type 2 and cognate DNA
Journal Articles

In vivo and in vitro growth of alveolar soft part sarcoma (ASPS)

David T. Vistica, Susan Kenney, Suzanne D. Borgel, Melinda G. Hollingshead, Anders S. Wallqvist, David G. Covell, David S. Schrump, Ming Zhao, Paula M. Krosky, Luke H. Stockwin, Donna O. Butcher, Dominic A. Scudiero, Robert H. Shoemaker
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 63.
Published: 15 April 2006
View article titled, In vivo and in vitro growth of alveolar soft part sarcoma (ASPS)
Journal Articles

Ligand-Directed Surface Profiling of Human Cancer Cells with Combinatorial Peptide Libraries

Mikhail G. Kolonin, Laura Bover, Jessica Sun, Amado J. Zurita, Kim-Anh Do, Johanna Lahdenranta, Marina Cardó-Vila, Ricardo J. Giordano, Diana E. Jaalouk, Michael G. Ozawa, Catherine A. Moya, Glauco R. Souza, Fernanda I. Staquicini, Akihiko Kunyiasu, Dominic A. Scudiero, Susan L. Holbeck, Edward A. Sausville, Wadih Arap, Renata Pasqualini
Journal: Cancer Research
Cancer Res (2006) 66 (1): 34–40.
https://doi.org/10.1158/0008-5472.CAN-05-2748
Published: 05 January 2006
View article titled, Ligand-Directed Surface Profiling of Human Cancer Cells with Combinatorial Peptide Libraries
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Includes: Supplementary data
Journal Articles

Substituted Purine Analogues Define a Novel Structural Class of Catalytic Topoisomerase II Inhibitors

Lars H. Jensen, Annemette V. Thougaard, Morten Grauslund, Birgitte Søkilde, Elisabeth V. Carstensen, Henrik K. Dvinge, Dominic A. Scudiero, Peter B. Jensen, Robert H. Shoemaker, Maxwell Sehested
Journal: Cancer Research
Cancer Res (2005) 65 (16): 7470–7477.
https://doi.org/10.1158/0008-5472.CAN-05-0707
Published: 15 August 2005
View article titled, Substituted Purine Analogues Define a Novel Structural Class of Catalytic Topoisomerase II Inhibitors
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Journal Articles

A C6-substituted guanine analog defines a novel class of ATP catalytic topoisomerase II inhibitors

Lars H. Jensen, Annemette Tuogaard, Birgitte Sokilde, Henrik K. Dvinge, Morten Grauslund, Elisabeth V. Carstensen, Eric Santoni-Rugiu, Dominic A. Scudiero, Robert H. Shoemaker, Peter B. Jensen, Maxwell Sehested
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 933–934.
Published: 01 May 2005
View article titled, A C6-substituted guanine analog defines a novel class of ATP catalytic topoisomerase II inhibitors
Journal Articles

Karyotypic Complexity of the NCI-60 Drug-Screening Panel

Anna V. Roschke, Giovanni Tonon, Kristen S. Gehlhaus, Nicolas McTyre, Kimberly J. Bussey, Samir Lababidi, Dominic A. Scudiero, John N. Weinstein, Ilan R. Kirsch
Journal: Cancer Research
Cancer Res (2003) 63 (24): 8634–8647.
Published: 24 December 2003
View article titled, Karyotypic Complexity of the NCI-60 Drug-Screening Panel
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Includes: Supplementary data
Journal Articles

Diagnostic Markers That Distinguish Colon and Ovarian Adenocarcinomas: Identification by Genomic, Proteomic, and Tissue Array Profiling

Satoshi Nishizuka, Sing-Tsung Chen, Fuad G. Gwadry, Jes Alexander, Sylvia M. Major, Uwe Scherf, William C. Reinhold, Mark Waltham, Lu Charboneau, Lynn Young, Kimberly J. Bussey, Sohyoung Kim, Samir Lababidi, Jae K. Lee, Stefania Pittaluga, Dominic A. Scudiero, Edward A. Sausville, Peter J. Munson, Emmanuel F. Petricoin, III, Lance A. Liotta, Stephen M. Hewitt, Mark Raffeld, John N. Weinstein
Journal: Cancer Research
Cancer Res (2003) 63 (17): 5243–5250.
Published: 18 September 2003
View article titled, Diagnostic Markers That Distinguish Colon and Ovarian Adenocarcinomas: <subtitle>Identification by Genomic, Proteomic, and Tissue Array Profiling</subtitle>
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Journal Articles

Identification of Small Molecule Inhibitors of Hypoxia-inducible Factor 1 Transcriptional Activation Pathway

Annamaria Rapisarda, Badarch Uranchimeg, Dominic A. Scudiero, Mike Selby, Edward A. Sausville, Robert H. Shoemaker, Giovanni Melillo
Journal: Cancer Research
Cancer Res (2002) 62 (15): 4316–4324.
Published: 01 August 2002
View article titled, Identification of Small Molecule Inhibitors of Hypoxia-inducible Factor 1 Transcriptional Activation Pathway
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Journal Articles

IAP-Family Protein Survivin Inhibits Caspase Activity and Apoptosis Induced by Fas (CD95), Bax, Caspases, and Anticancer Drugs

Ingo Tamm, Yan Wang, Ed Sausville, Dominic A. Scudiero, Nicole Vigna, Tilman Oltersdorf, John C. Reed
Journal: Cancer Research
Cancer Res (1998) 58 (23): 5315–5320.
Published: 01 December 1998
View article titled, IAP-Family Protein Survivin Inhibits Caspase Activity and Apoptosis Induced by Fas (CD95), Bax, Caspases, and Anticancer Drugs
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Journal Articles

Characterization of the p53 Tumor Suppressor Pathway in Cell Lines of the National Cancer Institute Anticancer Drug Screen and Correlations with the Growth-Inhibitory Potency of 123 Anticancer Agents

Patrick M. O'Connor, Joany Jackman, Insoo Bae, Timothy G. Myers, Saijun Fan, Masato Mutoh, Dominic A. Scudiero, Ann Monks, Edward A. Sausville, John N. Weinstein, Stephen Friend, Albert J. Fornace, Jr., Kurt W. Kohn
Journal: Cancer Research
Cancer Res (1997) 57 (19): 4285–4300.
Published: 01 October 1997
View article titled, Characterization of the <em>p53</em> Tumor Suppressor Pathway in Cell Lines of the National Cancer Institute Anticancer Drug Screen and Correlations with the Growth-Inhibitory Potency of 123 Anticancer Agents
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Journal Articles

An Abnormality in the p53 Pathway following γ-Irradiation in Many Wild-Type p53 Human Melanoma Lines

Insoo Bae, Martin L. Smith, M. Saeed Sheikh, Qimin Zhan, Dominic A. Scudiero, Stephen H. Friend, Patrick M. O'Connor, Albert J. Fornace, Jr.
Journal: Cancer Research
Cancer Res (1996) 56 (4): 840–847.
Published: 01 February 1996
View article titled, An Abnormality in the p53 Pathway following γ-Irradiation in Many Wild-Type p53 Human Melanoma Lines
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Journal Articles

Multidrug-resistant Phenotype of Disease-oriented Panels of Human Tumor Cell Lines Used for Anticancer Drug Screening

Lin Wu, Anne M. Smythe, Sherman F. Stinson, Leslie A. Mullendore, Anne Monks, Dominic A. Scudiero, Kenneth D. Paull, Antonis D. Koutsoukos, Lawrence V. Rubinstein, Michael R. Boyd, Robert H. Shoemaker
Journal: Cancer Research
Cancer Res (1992) 52 (11): 3029–3034.
Published: 01 June 1992
View article titled, Multidrug-resistant Phenotype of Disease-oriented Panels of Human Tumor Cell Lines Used for Anticancer Drug Screening
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Journal Articles

Evaluation of a Soluble Tetrazolium/Formazan Assay for Cell Growth and Drug Sensitivity in Culture Using Human and Other Tumor Cell Lines

Dominic A. Scudiero, Robert H. Shoemaker, Kenneth D. Paull, Anne Monks, Siobhan Tierney, Thomas H. Nofziger, Michael J. Currens, Donna Seniff, Michael R. Boyd
Journal: Cancer Research
Cancer Res (1988) 48 (17): 4827–4833.
Published: 01 September 1988
View article titled, Evaluation of a Soluble Tetrazolium/Formazan Assay for Cell Growth and Drug Sensitivity in Culture Using Human and Other Tumor Cell Lines
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Journal Articles

Feasibility of Drug Screening with Panels of Human Tumor Cell Lines Using a Microculture Tetrazolium Assay

Michael C. Alley, Dominic A. Scudiero, Anne Monks, Miriam L. Hursey, Maciej J. Czerwinski, Donald L. Fine, Betty J. Abbott, Joseph G. Mayo, Robert H. Shoemaker, Michael R. Boyd
Journal: Cancer Research
Cancer Res (1988) 48 (3): 589–601.
Published: 01 February 1988
View article titled, Feasibility of Drug Screening with Panels of Human Tumor Cell Lines Using a Microculture Tetrazolium Assay
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Journal Articles

Sensitivity of Human Cell Strains Having Different Abilities to Repair O6-Methylguanine in DNA to Inactivation by Alkylating Agents Including Chloroethylnitrosoureas

Dominic A. Scudiero, Sharon A. Meyer, Brian E. Clatterbuck, Michael R. Mattern, Chuck H. J. Ziolkowski, Rufus S. Day, III
Journal: Cancer Research
Cancer Res (1984) 44 (6): 2467–2474.
Published: 01 June 1984
View article titled, Sensitivity of Human Cell Strains Having Different Abilities to Repair <em>O</em><sup>6</sup>-Methylguanine in DNA to Inactivation by Alkylating Agents Including Chloroethylnitrosoureas
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Journal Articles

Relationship of DNA Repair Phenotypes of Human Fibroblast and Tumor Strains to Killing by N-Methyl-N′-nitro-N-nitrosoguanidine

Dominic A. Scudiero, Sharon A. Meyer, Brian E. Clatterbuck, Michael R. Mattern, Chuck H. J. Ziolkowski, Rufus S. Day, III
Journal: Cancer Research
Cancer Res (1984) 44 (3): 961–969.
Published: 01 March 1984
View article titled, Relationship of DNA Repair Phenotypes of Human Fibroblast and Tumor Strains to Killing by <em>N</em>-Methyl-<em>N′</em>-nitro-<em>N</em>-nitrosoguanidine
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