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Dmitriy Sonkin
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Journal Articles

Abstract 4884: Targeted investigational oncology agents (IOA) in the NCI60: a phenotypic systems-based resource

Joel Morris, Mark W. Kunkel, Stephen L. White, Donn G. Wishka, Omar D. Lopez, Lori Bowles, Penny Sellers, Patricia Ramsey, Julie Grams, Tiffany Rohrer, Karen Martin, Thomas Dexheimer, Dmitriy Sonkin, John D. Williams, Jerry M. Collins, James H. Doroshow, Beverly A. Teicher
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4884.
https://doi.org/10.1158/1538-7445.AM2023-4884
Published: 04 April 2023
View article titled, Abstract 4884: Targeted investigational oncology agents (IOA) in the NCI60: a phenotypic systems-based resource
Journal Articles

Abstract 1192: The Clinical Genome Resource (ClinGen) somatic cancer clinical domain working group

Jason Saliba, Gordana Raca, Angshumoy Roy, Ian King, Shamini Selvarajah, Xinjie Xu, Rashmi Kanagal-Shamanna, Laveniya Satgunaseelan, David Meredith, Mark Evans, Alanna Church, Panieh Terraf, Yassmine Akkari, Heather E. Williams, Wan-Hsin Lin, Chimene Kesserwan, Deborah I. Ritter, Kilannin Krysiak, Arpad Danos, Alex Wagner, Marilyn M. Li, Dmitriy Sonkin, Jonathan S. Berg, Sharon E. Plon, Heidi L. Rehm, Shashikant Kulkarni, Ramaswamy Govindan, Obi L. Griffith, Malachi Griffith, on behalf of the ClinGen Somatic CDWG
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1192.
https://doi.org/10.1158/1538-7445.AM2022-1192
Published: 15 June 2022
View article titled, Abstract 1192: The Clinical Genome Resource (ClinGen) somatic cancer clinical domain working group
Journal Articles

Abstract 449: A standard operating procedure for the curation of gene fusions

Alex H. Wagner, Ioannis S. Vlachos, Dmitriy Sonkin, Panieh Terraf, Chimene Kesserwan, Andrea Sboner, Thomas Coard, Christian Reich, Deborah I. Ritter, Peter Horak, Ying S. Zou, Anna Tanska, Aaron M. Berlin, Anna Lu, Daniel Cameron, Heather E. Williams, Wan-Hsin Lin, Gokce Toruner, Arpad Danos, Jason Saliba, Huiling Xu, Xinjie Xu, Georgina Ryland, Michele Ceccarelli, Liying Zhang, Sarah Rapisardo, Catherine Rehder, Xuelu Liu, Aparna Pallavajjala, Nicole Park, Laveniya Satgunaseelan, Kristy Lee, Jie Liu, Obi Griffith, Robert R. Freimuth, Albrecht Stenzinger, Linda B. Baughn, Michael Baudis, Jennifer Lee, Marilyn Li, Angshumoy Roy, Gordana Raca
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 449.
https://doi.org/10.1158/1538-7445.AM2021-449
Published: 01 July 2021
View article titled, Abstract 449: A standard operating procedure for the curation of gene fusions
Journal Articles

Abstract 1096: Harmonization standards from the Variant Interpretation for Cancer Consortium

Alex H. Wagner, Reece K. Hart, Larry Babb, Robert R. Freimuth, Adam Coffman, Yonghao Liang, Beth Pitel, Angshumoy Roy, Matthew Brush, Jennifer Lee, Anna Lu, Thomas Coard, Shruti Rao, Deborah Ritter, Brian Walsh, Susan Mockus, Peter Horak, Ian King, Dmitriy Sonkin, Subha Madhavan, Gordana Raca, Debyani Chakravarty, Malachi Griffith, Obi L. Griffith
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1096.
https://doi.org/10.1158/1538-7445.AM2020-1096
Published: 15 August 2020
View article titled, Abstract 1096: Harmonization standards from the Variant Interpretation for Cancer Consortium
Journal Articles

Abstract 3222: The Virtual Molecular Tumor Board of the Variant Interpretation for Cancer Consortium: A systematic gateway connecting cancer genome interpretation and progress in genomic knowledgebases in cancer

Beth A. Pitel, Shruti Rao, Catherine Del Vecchio Fitz, Subha Madhavan, Rodrigo Dientsmann, Peter Horak, Ian King, Susan M. Mockus, Gordana Raca, Damian T. Rieke, Peter Rogan, Dmitriy Sonkin, David Tamborero, Ioannis S. Vlachos, Brian Walsh, Jeremy L. Warner, Malachi Griffith, Obi L. Griffith, Debyani Chakravarty, Alex H. Wagner
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3222.
https://doi.org/10.1158/1538-7445.AM2020-3222
Published: 15 August 2020
View article titled, Abstract 3222: The Virtual Molecular Tumor Board of the Variant Interpretation for Cancer Consortium: A systematic gateway connecting cancer genome interpretation and progress in genomic knowledgebases in cancer
Journal Articles

Abstract 5707: A standard operating procedure for the interpretation of oncogenicity/pathogenicity of somatic mutations

Peter Horak, Malachi Griffith, Arpad Danos, Beth A. Pitel, Subha Madhavan, Xuelu Liu, Jennifer Lee, Gordana Raca, Shirley Li, Alex H. Wagner, Shashikant Kulkarni, Obi L. Griffith, Debyani Chakravarty, Dmitriy Sonkin
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5707.
https://doi.org/10.1158/1538-7445.AM2020-5707
Published: 15 August 2020
View article titled, Abstract 5707: A standard operating procedure for the interpretation of oncogenicity/pathogenicity of somatic mutations
Journal Articles

Abstract 5452: Neuroendocrine negative RB1 WT SCLC and LCNEC

Dmitriy Sonkin, Anish Thomas, Beverly A. Teicher
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5452.
https://doi.org/10.1158/1538-7445.AM2020-5452
Published: 15 August 2020
View article titled, Abstract 5452: Neuroendocrine negative RB1 WT SCLC and LCNEC
Journal Articles

Abstract 3215: ClinGen somatic cancer working group: Disseminating standardized cancer molecular diagnostic data and evidence through global collaboration and expert curation

Shruti Rao, Deborah Ritter, Arpad Danos, Gordana Raca, Angshumoy Roy, Kilannin Krysiak, Wan-Hsin Lin, Erica Barnell, Matthew McCoy, Beth Pitel, Dmitriy Sonkin, Jue Wang, Seyed Ali Hosseini, Shamini Selvarajah, Ian King, Rashmi Kanagal-Shamana, Xinjie Xu, Jeremy L. Warner, Funda Meric-Bernstam, Jason D. Merker, Marilyn Li, Alex H. Wagner, Malachi Griffith, Obi L. Griffith, Shashikant Kulkarni, Subha Madhavan
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3215.
https://doi.org/10.1158/1538-7445.AM2020-3215
Published: 15 August 2020
View article titled, Abstract 3215: ClinGen somatic cancer working group: Disseminating standardized cancer molecular diagnostic data and evidence through global collaboration and expert curation
Journal Articles

Abstract 2480: MutSpliceDB: A database of splice sites mutations effects

Alida Palmisano, Suleyman Vural, Yingdong Zhao, Dmitriy Sonkin
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2480.
https://doi.org/10.1158/1538-7445.AM2019-2480
Published: 01 July 2019
View article titled, Abstract 2480: MutSpliceDB: A database of splice sites mutations effects
Journal Articles

The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel

Anne Monks, Yingdong Zhao, Curtis Hose, Hossein Hamed, Julia Krushkal, Jianwen Fang, Dmitriy Sonkin, Alida Palmisano, Eric C. Polley, Laura K. Fogli, Mariam M. Konaté, Sarah B. Miller, Melanie A. Simpson, Andrea Regier Voth, Ming-Chung Li, Erik Harris, Xiaolin Wu, John W. Connelly, Annamaria Rapisarda, Beverly A. Teicher, Richard Simon, James H. Doroshow
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (24): 6807–6817.
https://doi.org/10.1158/0008-5472.CAN-18-0989
Published: 13 December 2018
View article titled, The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel
Open the PDF for The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel in another window
Includes: Supplementary data
Journal Articles

Abstract 3282: Standardization and coordination of variant interpretation knowledgebases improves clinical genome actionability

Alex H. Wagner, Brian Walsh, Dmitriy Sonkin, Rodrigo Dienstmann, Xuan S. Li, Jacques Beckmann, Georgia Mayfield, David Tamborero, Núria López-Bigas, Jeremy Goecks, Adam Margolin, Malachi Griffith, Obi Griffith
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3282.
https://doi.org/10.1158/1538-7445.AM2018-3282
Published: 01 July 2018
View article titled, Abstract 3282: Standardization and coordination of variant interpretation knowledgebases improves clinical genome actionability
Journal Articles

Abstract 207: CML as a prototypical malignancy

Dmitriy Sonkin, Richard Simon
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 207.
https://doi.org/10.1158/1538-7445.AM2018-207
Published: 01 July 2018
View article titled, Abstract 207: CML as a prototypical malignancy
Journal Articles

Abstract 4932: Neuro-endocrine negative SCLC is mostly RB1 WT and may be sensitive to CDK4/6 inhibition, especially if CCND1 is amplified

Dmitriy Sonkin, Anish Thomas, Beverly A. Teicher
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4932.
https://doi.org/10.1158/1538-7445.AM2018-4932
Published: 01 July 2018
View article titled, Abstract 4932: Neuro-endocrine negative SCLC is mostly RB1 WT and may be sensitive to CDK4/6 inhibition, especially if CCND1 is amplified
Journal Articles

Abstract 4831: Small cell lung carcinoma (SCLC) cell line screen of standard of care (etoposide/carboplatin) plus a third agent

Beverly A. Teicher, Michael Selby, Thomas Silvers, Julie Laudeman, Russell Reinhart, Rene Delosh, Chad Ogle, Ralph Parchment, Julia Krushkal, Dmitriy Sonkin, Joel Morris, Mark Kunkel, David Evans
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4831.
https://doi.org/10.1158/1538-7445.AM2017-4831
Published: 01 July 2017
View article titled, Abstract 4831: Small cell lung carcinoma (SCLC) cell line screen of standard of care (etoposide/carboplatin) plus a third agent
Journal Articles

Abstract LB-107: Inhibiting TNKS sensitizes KRAS mutant cancer cells to MEK inhibitors by suppressing FGFR2 feedback signaling

Wenlin Shao, Marie Schoumacher, Kristen Hurov, Joseph Lehar, Yan Yan-Neale, Yuji Mishina, Dmitriy Sonkin, Joshua Korn, Daisy Flemming, Michael Jones, Brandon Antonakos, Vessilina Cooke, Mark Stump, Nika Danial, William Sellers
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-107.
https://doi.org/10.1158/1538-7445.AM2014-LB-107
Published: 01 October 2014
View article titled, Abstract LB-107: Inhibiting TNKS sensitizes KRAS mutant cancer cells to MEK inhibitors by suppressing FGFR2 feedback signaling
Journal Articles

Inhibiting Tankyrases Sensitizes KRAS-Mutant Cancer Cells to MEK Inhibitors via FGFR2 Feedback Signaling

Marie Schoumacher, Kristen E. Hurov, Joseph Lehár, Yan Yan-Neale, Yuji Mishina, Dmitriy Sonkin, Joshua M. Korn, Daisy Flemming, Michael D. Jones, Brandon Antonakos, Vesselina G. Cooke, Janine Steiger, Jebediah Ledell, Mark D. Stump, William R. Sellers, Nika N. Danial, Wenlin Shao
Journal: Cancer Research
Cancer Res (2014) 74 (12): 3294–3305.
https://doi.org/10.1158/0008-5472.CAN-14-0138-T
Published: 12 June 2014
View article titled, Inhibiting Tankyrases Sensitizes KRAS-Mutant Cancer Cells to MEK Inhibitors via FGFR2 Feedback Signaling
Open the PDF for Inhibiting Tankyrases Sensitizes KRAS-Mutant Cancer Cells to MEK Inhibitors via FGFR2 Feedback Signaling in another window
Includes: Supplementary data
Journal Articles

Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer

Mohamed E. Abazeed, Drew J. Adams, Kristen E. Hurov, Pablo Tamayo, Chad J. Creighton, Dmitriy Sonkin, Andrew O. Giacomelli, Charles Du, Daniel F. Fries, Kwok-Kin Wong, Jill P. Mesirov, Jay S. Loeffler, Stuart L. Schreiber, Peter S. Hammerman, Matthew Meyerson
Journal: Cancer Research
Series: Author Choice
Cancer Res (2013) 73 (20): 6289–6298.
https://doi.org/10.1158/0008-5472.CAN-13-1616
Published: 14 October 2013
View article titled, Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer
Open the PDF for Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 5455: Integrative analysis of the Cancer Cell Line Encyclopedia reveals genetic and transcriptional predictors of compound sensitivity

Jordi Barretina, Nicolas Stransky, Giordano Caponigro, Sungjoon Kim, Adam Margolin, Kavitha Venkhatesan, Gregory Kryukov, Michael Berger, John Monahan, Paula Morais, Jodi Meltzer, Scott Mahan, Dmitriy Sonkin, Pichai Raman, Michael Jones, Vic Meyer, Christopher Wilson, Joseph Thibault, Lauren Murray, Adam Callahan, John Che, Aaron Shipway, Nanxin Li, Ingo Engels, Andrew Su, Reid Pinchback, Jared Nedzel, Ted Liefeld, Lili Niu, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Robert Onofrio, Carrie Sougnez, Laura MacConaill, Wendy Winckler, Michael Reich, Jill Mesirov, Kristin Ardlie, Gad Getz, Michael Morrissey, Markus Warmuth, Matthew Meyerson, Peter Finan, Todd Golub, Barbara Weber, Jennifer Harris, William Sellers, Robert Schlegel, Levi Garraway
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5455.
https://doi.org/10.1158/1538-7445.AM2011-5455
Published: 15 April 2011
View article titled, Abstract 5455: Integrative analysis of the Cancer Cell Line Encyclopedia reveals genetic and transcriptional predictors of compound sensitivity
Journal Articles

Abstract 105: Integrative analysis of genomic and pharmacologic data from the Cancer Cell Line Encyclopedia

Nicolas Stransky, Kavitha Venkhatesan, Mike Morrissey, Jordi Barretina, Pichai Raman, Gad Getz, Mike Berger, Cory Johannessen, Adam Callahan, Paula Morais, Scott Mahan, Supriya Gupta, Robert Onofrio, Carrie Sougnez, Wendy Winckler, Lili Niu, Sarah Kehoe, Charlie Hatton, Ted Liefeld, Yan Ding, Dmitriy Sonkin, Mike Jones, Giordiano Caponigro, Chris Wilson, Sungjoon Kim, John Che, Andrew Su, Laura MacConaill, Stacey Gabriel, Kristin Ardlie, Michael Reich, Markus Warmuth, Matthew Meyerson, Todd Golub, Jennifer Harris, William Sellers, Bob Schlegel, Levi Garraway
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 105.
https://doi.org/10.1158/1538-7445.AM10-105
Published: 15 April 2010
View article titled, Abstract 105: Integrative analysis of genomic and pharmacologic data from the Cancer Cell Line Encyclopedia
Journal Articles

Abstract 2620: The Cancer Cell Line Encyclopedia project: From integrative cancer genomics to personalized cancer therapy

Jordi Barretina, Giordano Caponigro, Sungjoon Kim, Nicolas Stransky, Kavitha Venkhatesan, Venkateshwar Reddy, Michael Berger, Michael Morrissey, Paula Morais, Jodi Meltzer, Joseph Thibault, Scott Mahan, Dmitriy Sonkin, John Che, Pichai Raman, Jessica Slind, Cory Johannessen, Supriya Gupta, Lili Niu, Sarah Kehoe, Charlie Hatton, Mike Jones, John Monahan, Vic Meyer, Chris Wilson, Aaron Shipway, Nanxin Li, Ingo Engels, Andrew Su, Adam Callahan, Yan Ding, Ted Liefeld, Liuda Ziaugra, Carrie Sougnez, Robert Onofrio, Wendy Winckler, Laura MacConaill, Michael Reich, Stacey Gabriel, Kristin Ardlie, Gad Getz, Markus Warmuth, Matthew Meyerson, Peter Finan, Todd Golub, Barbara Weber, Jennifer Harris, William Sellers, Robert Schlegel, Levi Garraway
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2620.
https://doi.org/10.1158/1538-7445.AM10-2620
Published: 15 April 2010
View article titled, Abstract 2620: The Cancer Cell Line Encyclopedia project: From integrative cancer genomics to personalized cancer therapy