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Journal Articles

Abstract 6213: Extracellular vesicles MDM2-DNA derived from dedifferentiated liposarcoma induces MMP2 production from preadipocytes

Free
Lucia Casadei, Federica Calore, Ameya Deshmukh, Abeba Zewdu, Paolo Fadda, Danielle Braggio, Martin Wabitsch, Carlo M. Croce, Dina Lev, Raphael Pollock
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6213.
https://doi.org/10.1158/1538-7445.AM2020-6213
Published: 15 August 2020
View articletitled, Abstract 6213: Extracellular vesicles MDM2-DNA derived from dedifferentiated liposarcoma induces MMP2 production from preadipocytes
Journal Articles

MDM2 Derived from Dedifferentiated Liposarcoma Extracellular Vesicles Induces MMP2 Production from Preadipocytes

Free
Lucia Casadei, Federica Calore, Danielle A. Braggio, Abeba Zewdu, Ameya A. Deshmukh, Paolo Fadda, Gonzalo Lopez, Martin Wabitsch, Chi Song, Jennifer L. Leight, Valerie P. Grignol, Dina Lev, Carlo M. Croce, Raphael E. Pollock
Journal: Cancer Research
Cancer Res (2019) 79 (19): 4911–4922.
https://doi.org/10.1158/0008-5472.CAN-19-0203
Published: 01 October 2019
View articletitled, MDM2 Derived from Dedifferentiated Liposarcoma Extracellular Vesicles Induces MMP2 Production from Preadipocytes
Open the PDF for MDM2 Derived from Dedifferentiated Liposarcoma Extracellular Vesicles Induces MMP2 Production from Preadipocytes in another window
Includes: Supplementary data
Journal Articles

Abstract 1891: Oncogenic MDM2-containing exosomes promote pre-metastatic niche establishment

Free
Lucia Casadei, Federica Calore, Ameya Deshmukh, Abeba Zewdu, Danielle A. Braggio, Paolo Fadda, Martin Wabitsch, Gonzalo Lopez, Jennifer Leight, Dina Lev, Carlo M. Croce, Raphael E. Pollock
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1891.
https://doi.org/10.1158/1538-7445.AM2019-1891
Published: 01 July 2019
View articletitled, Abstract 1891: Oncogenic MDM2-containing exosomes promote pre-metastatic niche establishment
Journal Articles

Exosome-Derived miR-25-3p and miR-92a-3p Stimulate Liposarcoma Progression

Free
Lucia Casadei, Federica Calore, Chad J. Creighton, Michele Guescini, Kara Batte, O. Hans Iwenofu, Abeba Zewdu, Danielle A. Braggio, Kate Lynn Bill, Paolo Fadda, Francesca Lovat, Gonzalo Lopez, Pierluigi Gasparini, James L. Chen, Raleigh D. Kladney, Gustavo Leone, Dina Lev, Carlo M. Croce, Raphael E. Pollock
Journal: Cancer Research
Cancer Res (2017) 77 (14): 3846–3856.
https://doi.org/10.1158/0008-5472.CAN-16-2984
Published: 13 July 2017
View articletitled, Exosome-Derived miR-25-3p and miR-92a-3p Stimulate Liposarcoma Progression
Open the PDF for Exosome-Derived miR-25-3p and miR-92a-3p Stimulate Liposarcoma Progression in another window
Includes: Supplementary data
Journal Articles

Abstract 286: Preclinical study: HDAC inhibition combined with gemcitabine for the treatment of leiomyosarcoma

Free
Gonzalo Lopez, Edwin Choy, Shreyaskumar Patel, Hemant Bid, Danielle Braggio, Dina Lev, Raphael Pollock
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 286.
https://doi.org/10.1158/1538-7445.AM2016-286
Published: 15 July 2016
View articletitled, Abstract 286: Preclinical study: HDAC inhibition combined with gemcitabine for the treatment of leiomyosarcoma
Journal Articles

Abstract 2286: Targeting the notch pathway: A potential therapeutic approach for desmoid tumors

Free
Danielle Braggio, Hui Shang, Ya-Jung Lee, Ghadah A. Al-Sannaa, Chad J. Creighton, Svetlana Bolshakov, Alexander JF Lazar, Dina Lev, Raphael E. Pollock
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2286.
https://doi.org/10.1158/1538-7445.AM2016-2286
Published: 15 July 2016
View articletitled, Abstract 2286: Targeting the notch pathway: A potential therapeutic approach for desmoid tumors
Journal Articles

Abstract LB-251: Histone deacetylase inhibition for the treatment of epithelioid sarcoma; novel cross talk between epigenetic components

Free
Gonzalo Lopez, Yechun Song, Dennis Ruder, Chad Creighton Creighton, Svetlana Bolshakov, Xiaoli Zhang, Dina Lev, Raphael Pollock
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-251.
https://doi.org/10.1158/1538-7445.AM2015-LB-251
Published: 01 August 2015
View articletitled, Abstract LB-251: Histone deacetylase inhibition for the treatment of epithelioid sarcoma; novel cross talk between epigenetic components
Journal Articles

Akt1 and Akt3 Exert Opposing Roles in the Regulation of Vascular Tumor Growth

Free
Thuy L. Phung, Wa Du, Qi Xue, Sriram Ayyaswamy, Damien Gerald, Zeus Antonello, Sokha Nhek, Carole A. Perruzzi, Isabel Acevedo, Rajesh Ramanna-Valmiki, Paul Rodriguez-Waitkus, Ladan Enayati, Marcelo L. Hochman, Dina Lev, Sandaruwan Geeganage, Laura E. Benjamin
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (1): 40–50.
https://doi.org/10.1158/0008-5472.CAN-13-2961
Published: 04 January 2015
View articletitled, Akt1 and Akt3 Exert Opposing Roles in the Regulation of Vascular Tumor Growth
Open the PDF for Akt1 and Akt3 Exert Opposing Roles in the Regulation of Vascular Tumor Growth in another window
Includes: Supplementary data
Journal Articles

Abstract 5242: miR-10b functions as a novel tumor suppressor in uterine leiomyosarcoma by promoting overexpression of SDC1

Free
Matthew L. Anderson, Gyoung Eun Kim, Claire M. Mach, Chad J. Creighton, Dina Lev
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5242.
https://doi.org/10.1158/1538-7445.AM2014-5242
Published: 01 October 2014
View articletitled, Abstract 5242: miR-10b functions as a novel tumor suppressor in uterine leiomyosarcoma by promoting overexpression of SDC1
Journal Articles

Abstract 1469: Specific detection tool for mesenchymal and epithelial-mesenchymal transformed circulating tumor cells.

Free
Arun Satelli, Abhisek Mitra, Jeffery J. Cutrera, Xia Xeuqing, Dibra Denada, Dina Lev Chelouche, Michael James Overman, Ellis Lee, Shulin Li
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1469.
https://doi.org/10.1158/1538-7445.AM2013-1469
Published: 15 April 2013
View articletitled, Abstract 1469: Specific detection tool for mesenchymal and epithelial-mesenchymal transformed circulating tumor cells.
Journal Articles

Unphosphorylated STAT1 Promotes Sarcoma Development through Repressing Expression of Fas and Bad and Conferring Apoptotic Resistance

Free
Mary A. Zimmerman, Nur-Taz Rahman, Dafeng Yang, Guy Lahat, Alexander J. Lazar, Raphael E. Pollock, Dina Lev, Kebin Liu
Journal: Cancer Research
Cancer Res (2012) 72 (18): 4724–4732.
https://doi.org/10.1158/0008-5472.CAN-12-1347
Published: 16 September 2012
View articletitled, Unphosphorylated STAT1 Promotes Sarcoma Development through Repressing Expression of Fas and Bad and Conferring Apoptotic Resistance
Open the PDF for Unphosphorylated STAT1 Promotes Sarcoma Development through Repressing Expression of Fas and Bad and Conferring Apoptotic Resistance in another window
Includes: Supplementary data
Journal Articles

Ikk4a/Arf Inactivation with Activation of the NF-κB/IL-6 Pathway Is Sufficient to Drive the Development and Growth of Angiosarcoma

Free
Jinming Yang, Sara Kantrow, Jiqing Sai, Oriana E. Hawkins, Mark Boothby, Gregory D. Ayers, Eric D. Young, Elizabeth G. Demicco, Alexander J. Lazar, Dina Lev, Ann Richmond
Journal: Cancer Research
Cancer Res (2012) 72 (18): 4682–4695.
https://doi.org/10.1158/0008-5472.CAN-12-0440
Published: 16 September 2012
View articletitled, Ikk4a/Arf Inactivation with Activation of the NF-κB/IL-6 Pathway Is Sufficient to Drive the Development and Growth of Angiosarcoma
Open the PDF for Ikk4a/Arf Inactivation with Activation of the NF-κB/IL-6 Pathway Is Sufficient to Drive the Development and Growth of Angiosarcoma in another window
Includes: Supplementary data
Journal Articles

MiR-155 Is a Liposarcoma Oncogene That Targets Casein Kinase-1α and Enhances β-Catenin Signaling

Free
Pingyu Zhang, Katelynn Bill, Juehui Liu, Eric Young, Tingsheng Peng, Svetlana Bolshakov, Aviad Hoffman, Yechun Song, Elizabeth G. Demicco, Dolores Lopez Terrada, Chad J. Creighton, Matthew L. Anderson, Alexander J. Lazar, George G. Calin, Raphael E. Pollock, Dina Lev
Journal: Cancer Research
Cancer Res (2012) 72 (7): 1751–1762.
https://doi.org/10.1158/0008-5472.CAN-11-3027
Published: 01 April 2012
View articletitled, MiR-155 Is a Liposarcoma Oncogene That Targets Casein Kinase-1α and Enhances β-Catenin Signaling
Open the PDF for MiR-155 Is a Liposarcoma Oncogene That Targets Casein Kinase-1α and Enhances β-Catenin Signaling in another window
Includes: Supplementary data
Journal Articles

Abstract 2019: An epigenetic reactivation screen identifies pathways important in pleomorphic liposarcomas

Free
Kara Pascarelli, Matthew Plantinga, Katherine Doyle, Chad Roberts, Yan Zhou, Margaret von Mehren, Dina Lev, Dominique Broccoli
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2019.
https://doi.org/10.1158/1538-7445.AM2011-2019
Published: 15 April 2011
View articletitled, Abstract 2019: An epigenetic reactivation screen identifies pathways important in pleomorphic liposarcomas
Journal Articles

Autophagic Survival in Resistance to Histone Deacetylase Inhibitors: Novel Strategies to Treat Malignant Peripheral Nerve Sheath Tumors

Free
Gonzalo Lopez, Keila Torres, Juehui Liu, Belinda Hernandez, Eric Young, Roman Belousov, Svetlana Bolshakov, Alexander J. Lazar, John M. Slopis, Ian E. McCutcheon, David McConkey, Dina Lev
Journal: Cancer Research
Cancer Res (2011) 71 (1): 185–196.
https://doi.org/10.1158/0008-5472.CAN-10-2799
Published: 02 January 2011
View articletitled, Autophagic Survival in Resistance to Histone Deacetylase Inhibitors: Novel Strategies to Treat Malignant Peripheral Nerve Sheath Tumors
Open the PDF for Autophagic Survival in Resistance to Histone Deacetylase Inhibitors: Novel Strategies to Treat Malignant Peripheral Nerve Sheath Tumors in another window
Includes: Supplementary data
Journal Articles

Abstract 1783: Activated c-MET; a prognostic factor and potential therapeutic target for malignant peripheral nerve sheath tumors (MPNST)

Free
Keila E. Torres, Markus Ghadimi, Suizhao Wang, Jun Liu, Alexander Lazar, Raphael E. Pollock, Dina Lev
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1783.
https://doi.org/10.1158/1538-7445.AM10-1783
Published: 15 April 2010
View articletitled, Abstract 1783: Activated c-MET; a prognostic factor and potential therapeutic target for malignant peripheral nerve sheath tumors (MPNST)
Journal Articles

Abstract 4855: Role of HDACi-induced autophagy in malignant peripheral nerve sheath tumors (MPNST)

Free
Keila E. Torres, Gonzalo Lopez, Juehui Liu, Raphael E. Pollock, Dina Lev
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4855.
https://doi.org/10.1158/1538-7445.AM10-4855
Published: 15 April 2010
View articletitled, Abstract 4855: Role of HDACi-induced autophagy in malignant peripheral nerve sheath tumors (MPNST)
Journal Articles

Abstract 642: Vimentin is a novel anticancer therapeutic target

Free
Quansheng Zhu, Guy Lahat, Svetlana Bolshakov, Jeffery Liu, Keila Torres, Robert R. Langley, Alexander J. Lazar, Mien Chie Hung, Dina Lev
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 642.
https://doi.org/10.1158/1538-7445.AM10-642
Published: 15 April 2010
View articletitled, Abstract 642: Vimentin is a novel anticancer therapeutic target
Journal Articles

Abstract #2819: Dual targeting of AKT and mTOR: A potential therapeutic approach for the malignant peripheral nerve sheath tumors

Free
Quansheng Zhu, Changye Zou, Kerry D Smith, Ie McCutcheon, Jm Slopis, F Meric-Bernstam, Wg Bornmann, G Mills, AJ Lazar, Re Pollock, Dina Lev
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2819.
Published: 01 May 2009
View articletitled, Abstract #2819: Dual targeting of AKT and mTOR: A potential therapeutic approach for the malignant peripheral nerve sheath tumors
Journal Articles

Abstract #5142: IFN regulatory factor 8 suppresses FLICE-like protein expression to sensitizes soft tissue sarcoma cells to FasL- and TRAIL-induced apoptosis

Free
Dafeng Yang, Suizhao Wang, Craig Brooks, Zheng Dong, Patricia Schoenlein, Vijay Kumar, Xinshou Ouyang, Huabao Xiong, Guy Lahat, Andrea Hayes-Jordan, Alexander Lazar, Raphael Pollock, Dina Lev, Kebin Liu
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 5142.
Published: 01 May 2009
View articletitled, Abstract #5142: IFN regulatory factor 8 suppresses FLICE-like protein expression to sensitizes soft tissue sarcoma cells to FasL- and TRAIL-induced apoptosis