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Dietrich Hoffmann
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Journal Articles

Increased Expression of Cyclooxygenase-2 in Rat Lung Tumors Induced by the Tobacco-specific Nitrosamine 4-(Methylnitrosamino)-4-(3-pyridyl)-1-butanone: The Impact of a High-Fat Diet

Karam El-Bayoumy, Michael Iatropoulos, Shantu Amin, Dietrich Hoffmann, Ernst L. Wynder
Journal: Cancer Research
Cancer Res (1999) 59 (7): 1400–1403.
Published: 01 April 1999
View article titled, Increased Expression of Cyclooxygenase-2 in Rat Lung Tumors Induced by the Tobacco-specific Nitrosamine 4-(Methylnitrosamino)-4-(3-pyridyl)-1-butanone: <subtitle>The Impact of a High-Fat Diet</subtitle>
Open the PDF for Increased Expression of Cyclooxygenase-2 in Rat Lung Tumors Induced by the Tobacco-specific Nitrosamine 4-(Methylnitrosamino)-4-(3-pyridyl)-1-butanone: <subtitle>The Impact of a High-Fat Diet</subtitle> in another window
Journal Articles

Smoking and Lung Cancer: Scientific Challenges and Opportunities

Ernst L. Wynder, Dietrich Hoffmann
Journal: Cancer Research
Cancer Res (1994) 54 (20): 5284–5295.
Published: 01 October 1994
View article titled, Smoking and Lung Cancer: Scientific Challenges and Opportunities
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Journal Articles

A Study of Tobacco Carcinogenesis: Effect of the Fat Content of the Diet on the Carcinogenic Activity of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone in F344 Rats

Dietrich Hoffmann, Abraham Rivenson, Rakesh Abbi, Ernst L. Wynder
Journal: Cancer Research
Cancer Res (1993) 53 (12): 2758–2761.
Published: 01 June 1993
View article titled, A Study of Tobacco Carcinogenesis: Effect of the Fat Content of the Diet on the Carcinogenic Activity of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone in F344 Rats
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Journal Articles

Evaluation of the Transplacental Tumorigenicity of the Tobacco-specific Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone in Mice

Lucy M. Anderson, Stephen S. Hecht, Dwayne E. Dixon, Lee F. Dove, Robert M. Kovatch, Shantu Amin, Dietrich Hoffmann, Jerry M. Rice
Journal: Cancer Research
Cancer Res (1989) 49 (14): 3770–3775.
Published: 01 July 1989
View article titled, Evaluation of the Transplacental Tumorigenicity of the Tobacco-specific Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone in Mice
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Journal Articles

Cyanoethylation of DNA in Vivo by 3-(Methylnitrosamino)propionitrile, an Areca-derived Carcinogen

Bogdan Prokopczyk, Peter Bertinato, Dietrich Hoffmann
Journal: Cancer Research
Cancer Res (1988) 48 (23): 6780–6784.
Published: 01 December 1988
View article titled, Cyanoethylation of DNA <em>in Vivo</em> by 3-(Methylnitrosamino)propionitrile, an <em>Areca</em>-derived Carcinogen
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Journal Articles

Induction of Lung and Exocrine Pancreas Tumors in F344 Rats by Tobacco-specific and Areca-derived N-Nitrosamines

Abraham Rivenson, Dietrich Hoffmann, Bogdan Prokopczyk, Shantu Amin, Stephen S. Hecht
Journal: Cancer Research
Cancer Res (1988) 48 (23): 6912–6917.
Published: 01 December 1988
View article titled, Induction of Lung and Exocrine Pancreas Tumors in F344 Rats by Tobacco-specific and <em>Areca</em>-derived <em>N</em>-Nitrosamines
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Journal Articles

Biochemical Epidemiology of Cervical Neoplasia: Measuring Cigarette Smoke Constitutents in the Cervix

Mark H. Schiffman, Nancy J. Haley, James S. Felton, A. W. Andrews, Richard A. Kaslow, Wayne D. Lancaster, Robert J. Kurman, Louise A. Brinton, Linda B. Lannom, Dietrich Hoffmann
Journal: Cancer Research
Cancer Res (1987) 47 (14): 3886–3888.
Published: 01 July 1987
View article titled, Biochemical Epidemiology of Cervical Neoplasia: Measuring Cigarette Smoke Constitutents in the Cervix
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Journal Articles

3-(Methylnitrosamino)propionitrile: Occurrence in Saliva of Betel Quid Chewers, Carcinogenicity, and DNA Methylation in F344 Rats

Bogdan Prokopczyk, Abraham Rivenson, Peter Bertinato, Klaus D. Brunnemann, Dietrich Hoffmann
Journal: Cancer Research
Cancer Res (1987) 47 (2): 467–471.
Published: 01 January 1987
View article titled, 3-(Methylnitrosamino)propionitrile: Occurrence in Saliva of Betel Quid Chewers, Carcinogenicity, and DNA Methylation in F344 Rats
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Journal Articles

Identification and Quantitative Determination of Aniline and Toluidines in Human Urine

Karam El-Bayoumy, Jean M. Donahue, Stephen S. Hecht, Dietrich Hoffmann
Journal: Cancer Research
Cancer Res (1986) 46 (12_Part_1): 6064–6067.
Published: 01 December 1986
View article titled, Identification and Quantitative Determination of Aniline and Toluidines in Human Urine
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Journal Articles

Induction of Oral Cavity Tumors in F344 Rats by Tobacco-specific Nitrosamines and Snuff

Stephen S. Hecht, Abraham Rivenson, Joanne Braley, Joann DiBello, John D. Adams, Dietrich Hoffmann
Journal: Cancer Research
Cancer Res (1986) 46 (8): 4162–4166.
Published: 01 August 1986
View article titled, Induction of Oral Cavity Tumors in F344 Rats by Tobacco-specific Nitrosamines and Snuff
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Journal Articles

Rates of Hydrolysis and Extents of DNA Binding of 5-Methylchrysene Dihydrodiol Epoxides

Assieh A. Melikian, Joanna M. Leszczynska, Shantu Amin, Stephen S. Hecht, Dietrich Hoffmann, John Pataki, Ronald G. Harvey
Journal: Cancer Research
Cancer Res (1985) 45 (5): 1990–1996.
Published: 01 May 1985
View article titled, Rates of Hydrolysis and Extents of DNA Binding of 5-Methylchrysene Dihydrodiol Epoxides
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Journal Articles

Tumorigenicity of 5-Methylchrysene Dihydrodiols and Dihydrodiol Epoxides in Newborn Mice and on Mouse Skin

Stephen S. Hecht, Lynn Radok, Shantu Amin, Keith Huie, Assieh A. Melikian, Dietrich Hoffmann, John Pataki, Ronald G. Harvey
Journal: Cancer Research
Cancer Res (1985) 45 (4): 1449–1452.
Published: 01 April 1985
View article titled, Tumorigenicity of 5-Methylchrysene Dihydrodiols and Dihydrodiol Epoxides in Newborn Mice and on Mouse Skin
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Journal Articles

Nicotine-derived N-Nitrosamines and Tobacco-related Cancer: Current Status and Future Directions

Dietrich Hoffmann, Stephen S. Hecht
Journal: Cancer Research
Cancer Res (1985) 45 (3): 935–944.
Published: 01 March 1985
View article titled, Nicotine-derived <em>N</em>-Nitrosamines and Tobacco-related Cancer: Current Status and Future Directions
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Journal Articles

Identification of the Major Adducts Formed by Reaction of 5-Methylchrysene Anti-Dihydrodiol-Epoxides with DNA in Vitro

Assieh A. Melikian, Shantu Amin, Stephen S. Hecht, Dietrich Hoffmann, John Pataki, Ronald G. Harvey
Journal: Cancer Research
Cancer Res (1984) 44 (6): 2524–2529.
Published: 01 June 1984
View article titled, Identification of the Major Adducts Formed by Reaction of 5-Methylchrysene Anti-Dihydrodiol-Epoxides with DNA <em>in Vitro</em>
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Journal Articles

Endogenous Formation of N-Nitrosoproline in Cigarette Smokers

Dietrich Hoffmann, Klaus D. Brunnemann
Journal: Cancer Research
Cancer Res (1983) 43 (11): 5570–5574.
Published: 01 November 1983
View article titled, Endogenous Formation of <em>N</em>-Nitrosoproline in Cigarette Smokers
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Journal Articles

Effects of Route of Administration and Dose on the Carcinogenicity of N-Nitrosodiethanolamine in the Syrian Golden Hamster

Dietrich Hoffmann, Abraham Rivenson, John D. Adams, Amy Juchatz, Norma Vinchkoski, Stephen S. Hecht
Journal: Cancer Research
Cancer Res (1983) 43 (6): 2521–2524.
Published: 01 June 1983
View article titled, Effects of Route of Administration and Dose on the Carcinogenicity of <em>N</em>-Nitrosodiethanolamine in the Syrian Golden Hamster
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Journal Articles

Tumor-initiating Activity and Metabolism of Polymethylated Phenanthrenes

Edmond J. LaVoie, Victoria Bedenko, Lorraine Tulley-Freller, Dietrich Hoffmann
Journal: Cancer Research
Cancer Res (1982) 42 (10): 4045–4049.
Published: 01 October 1982
View article titled, Tumor-initiating Activity and Metabolism of Polymethylated Phenanthrenes
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Journal Articles

Influence of a Bay-Region Methyl Group on Formation of 5-Methylchrysene Dihydrodiol Epoxide:DNA Adducts in Mouse Skin

Assieh A. Melikian, Edmond J. LaVole, Stephen S. Hecht, Dietrich Hoffmann
Journal: Cancer Research
Cancer Res (1982) 42 (4): 1239–1242.
Published: 01 April 1982
View article titled, Influence of a Bay-Region Methyl Group on Formation of 5-Methylchrysene Dihydrodiol Epoxide:DNA Adducts in Mouse Skin
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Journal Articles

Reduction of Tumorigenicity and of Dihydrodiol Formation by Fluorine Substitution in the Angular Rings of Dibenzo(a,i)pyrene

Stephen S. Hecht, Edmond J. LaVoie, Victoria Bedenko, Linda Pingaro, Shoichi Katayama, Dietrich Hoffmann, Dennis J. Sardella, Eliahu Boger, Roland E. Lehr
Journal: Cancer Research
Cancer Res (1981) 41 (11_Part_1): 4341–4345.
Published: 01 November 1981
View article titled, Reduction of Tumorigenicity and of Dihydrodiol Formation by Fluorine Substitution in the Angular Rings of Dibenzo(<em>a,i</em>)pyrene
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Journal Articles

Carcinogenic Tobacco-specific N-Nitrosamines in Snuff and in the Saliva of Snuff Dippers

Dietrich Hoffmann, John D. Adams
Journal: Cancer Research
Cancer Res (1981) 41 (11_Part_1): 4305–4308.
Published: 01 November 1981
View article titled, Carcinogenic Tobacco-specific <em>N</em>-Nitrosamines in Snuff and in the Saliva of Snuff Dippers
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