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Diego Arango
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Journal Articles

Abstract 847: Role of RHOA in diffuse gastric cancer tumors

Agueda Martinez-Barriocanal, Higinio Dopeso, Lizbeth M. Jiménez-Flores, Juliana C. Santos, Estefania Anguita, Josipa Bilic, Rocio Nieto, Elia García-Vidal, Manuel Sánchez Martín, Stefania Landolfi, Kazuto Kobayashi, Javier Hernandez-Losa, Simo Schwartz, Santiago Ramón y Cajal, Diego Arango
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 847.
https://doi.org/10.1158/1538-7445.AM2022-847
Published: 15 June 2022
View article titled, Abstract 847: Role of RHOA in diffuse gastric cancer tumors
Journal Articles

Abstract 840: Identification of novel colorectal tumor suppressor genes through genome-wide promoter hypermethylation analysis

Sarah Bazzocco, Jose Higinio Dopeso, Águeda Martínez-Barriocanal, Estefanía Anguita, Rocio Nieto, Alex Sanchez, John M. Mariadason, Diego Arango
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 840.
https://doi.org/10.1158/1538-7445.AM2019-840
Published: 01 July 2019
View article titled, Abstract 840: Identification of novel colorectal tumor suppressor genes through genome-wide promoter hypermethylation analysis
Journal Articles

Abstract 2058: RHOA inactivation enhances Wnt signaling and promotes colorectal cancer

Paulo Rodrigues, Irati Macaya, Sarah Bazzocco, Elena Andretta, Rocco Mazzolini, Higinio Dopeso, Silvia Mateo-Lozano, Josipa Bilic, Fernando Cartón-García, Rocio Nieto, Lucia Suárez-López, Elsa Afonso, Stefania Landolfi, Javier Hernandez-Losa, Kazuto Kobayashi, Santiago Ramón y Cajal, Josep Tabernero, Niall C. Tebbutt, John M. Mariadason, Simo Schwartz Jr, Diego Arango
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2058.
https://doi.org/10.1158/1538-7445.AM2015-2058
Published: 01 August 2015
View article titled, Abstract 2058: RHOA inactivation enhances Wnt signaling and promotes colorectal cancer
Journal Articles

Abstract 5172: Whole exome mutation landscape of 70 commonly used colorectal cancer cell lines

Oliver Sieber, Dmitri Mouradov, Clare Sloggett, Robert Jorissen, Chris Love, Shan Li, Antony Burgess, Diego Arango, Robert Strausberg, Daniel Buchanan, Samuel Wormald, Liam O'Connor, Jenny Wilding, David Bicknell, Ian Tomlinson, Walter Bodmer, John Mariadason
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5172.
https://doi.org/10.1158/1538-7445.AM2014-5172
Published: 01 October 2014
View article titled, Abstract 5172: Whole exome mutation landscape of 70 commonly used colorectal cancer cell lines
Journal Articles

Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer

Dmitri Mouradov, Clare Sloggett, Robert N. Jorissen, Christopher G. Love, Shan Li, Antony W. Burgess, Diego Arango, Robert L. Strausberg, Daniel Buchanan, Samuel Wormald, Liam O'Connor, Jennifer L. Wilding, David Bicknell, Ian P.M. Tomlinson, Walter F. Bodmer, John M. Mariadason, Oliver M. Sieber
Journal: Cancer Research
Cancer Res (2014) 74 (12): 3238–3247.
https://doi.org/10.1158/0008-5472.CAN-14-0013
Published: 12 June 2014
View article titled, Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer
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Includes: Supplementary data
Journal Articles

Abstract 2991: Coordinate methylation of the alkaline phosphatase gene family in colon cancer. Implications for understanding the manifestation of the CpG island methylator phenotype (CIMP). .

John Mariadason, Azadeh Carr, Georgia A. Corner, Sheren Al-Obaidi, Anderly Chueh, Fiona Chionh, Lars Tögel, Naseem Ahmed, Diego Arango, Daniel Buchanan, Joanne Young, Leonard H. Augenlicht, Madhu S. Malo, Richard Hodin, Oliver M. Sieber, Thomas Weber, Joongho Shin
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2991.
https://doi.org/10.1158/1538-7445.AM2013-2991
Published: 15 April 2013
View article titled, Abstract 2991: Coordinate methylation of the alkaline phosphatase gene family in colon cancer. Implications for understanding the manifestation of the CpG island methylator phenotype (CIMP). .
Journal Articles

Abstract 4316: Villin expression is frequently lost in colon cancers with microsatellite instability.

Diego Arango, Sheren Al-Obaidi, David S. Williams, Jose Dopeso, Rocco Mazzolini, Georgia A. Corner, Do-Sun Byun, Carmel Murone, Lars Togel, Nikolajs Zeps, Lauri A. Aaltonen, Barry Iacopetta, John Martin Mariadason
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4316.
https://doi.org/10.1158/1538-7445.AM2012-4316
Published: 15 April 2012
View article titled, Abstract 4316: Villin expression is frequently lost in colon cancers with microsatellite instability.
Journal Articles

Abstract 4921: Selective promoter methylation of the cell differentiation marker, intestinal alkaline phosphatase (iALP), in microsatellite unstable colon cancer

Joongho Shin, Azadeh Azarbayejani, Victoria Lai, Naseem Ahmed, Richard Hodin, Madhu Malo, Diego Arango, Thomas Weber, John M. Mariadason
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4921.
https://doi.org/10.1158/1538-7445.AM10-4921
Published: 15 April 2010
View article titled, Abstract 4921: Selective promoter methylation of the cell differentiation marker, intestinal alkaline phosphatase (iALP), in microsatellite unstable colon cancer
Journal Articles

Apoptotic Sensitivity of Colon Cancer Cells to Histone Deacetylase Inhibitors Is Mediated by an Sp1/Sp3-Activated Transcriptional Program Involving Immediate-Early Gene Induction

Andrew J. Wilson, Anderly C. Chueh, Lars Tögel, Georgia A. Corner, Naseem Ahmed, Sanjay Goel, Do-Sun Byun, Shannon Nasser, Michele A. Houston, Minaxi Jhawer, Helena J.M. Smartt, Lucas B. Murray, Courtney Nicholas, Barbara G. Heerdt, Diego Arango, Leonard H. Augenlicht, John M. Mariadason
Journal: Cancer Research
Cancer Res (2010) 70 (2): 609–620.
https://doi.org/10.1158/0008-5472.CAN-09-2327
Published: 13 January 2010
View article titled, Apoptotic Sensitivity of Colon Cancer Cells to Histone Deacetylase Inhibitors Is Mediated by an Sp1/Sp3-Activated Transcriptional Program Involving Immediate-Early Gene Induction
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Includes: Supplementary data
Journal Articles

An A13 Repeat within the 3′-Untranslated Region of Epidermal Growth Factor Receptor (EGFR) Is Frequently Mutated in Microsatellite Instability Colon Cancers and Is Associated with Increased EGFR Expression

Ziqiang Yuan, Joongho Shin, Andrew Wilson, Sanjay Goel, Yi-He Ling, Naseem Ahmed, Higinio Dopeso, Minaxi Jhawer, Shannon Nasser, Cristina Montagna, Kenneth Fordyce, Leonard H. Augenlicht, Lauri A. Aaltonen, Diego Arango, Thomas K. Weber, John M. Mariadason
Journal: Cancer Research
Cancer Res (2009) 69 (19): 7811–7818.
https://doi.org/10.1158/0008-5472.CAN-09-0986
Published: 01 October 2009
View article titled, An A13 Repeat within the 3′-Untranslated Region of Epidermal Growth Factor Receptor (EGFR) Is Frequently Mutated in Microsatellite Instability Colon Cancers and Is Associated with Increased EGFR Expression
Open the PDF for An A13 Repeat within the 3′-Untranslated Region of Epidermal Growth Factor Receptor (EGFR) Is Frequently Mutated in Microsatellite Instability Colon Cancers and Is Associated with Increased EGFR Expression in another window
Includes: Supplementary data
Journal Articles

The Receptor Tyrosine Kinase EPHB4 Has Tumor Suppressor Activities in Intestinal Tumorigenesis

Higinio Dopeso, Silvia Mateo-Lozano, Rocco Mazzolini, Paulo Rodrigues, Laura Lagares-Tena, Julian Ceron, Jordi Romero, Marielle Esteves, Stefania Landolfi, Javier Hernández-Losa, Julio Castaño, Andrew J. Wilson, Santiago Ramon y Cajal, John M. Mariadason, Simo Schwartz, Jr., Diego Arango
Journal: Cancer Research
Cancer Res (2009) 69 (18): 7430–7438.
https://doi.org/10.1158/0008-5472.CAN-09-0706
Published: 14 September 2009
View article titled, The Receptor Tyrosine Kinase EPHB4 Has Tumor Suppressor Activities in Intestinal Tumorigenesis
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Includes: Supplementary data
Journal Articles

Mutatome of microsatellite unstable colorectal cancer

Heli Sammalkorpi, Pia Alhopuro, Diego Arango, Mia Bistrom, Sampsa Hautaniemi, Elina Heliovaara, Heikki Jarvinen, Auli Karhu, Jukka-Pekka Mecklin, Iina Niittymaki, Kari Nousiainen, Torben Orntoft, Jani Puhakka, Anniina Raitila, Juha Saharinen, Sari Tuupanen, Lauri Aaltonen
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5783.
Published: 01 May 2008
View article titled, Mutatome of microsatellite unstable colorectal cancer
Journal Articles

PIK3CA Mutation/PTEN Expression Status Predicts Response of Colon Cancer Cells to the Epidermal Growth Factor Receptor Inhibitor Cetuximab

Minaxi Jhawer, Sanjay Goel, Andrew J. Wilson, Cristina Montagna, Yi-He Ling, Do-Sun Byun, Shannon Nasser, Diego Arango, Joongho Shin, Lidija Klampfer, Leonard H. Augenlicht, Roman Perez Soler, John M. Mariadason
Journal: Cancer Research
Cancer Res (2008) 68 (6): 1953–1961.
https://doi.org/10.1158/0008-5472.CAN-07-5659
Published: 13 March 2008
View article titled, PIK3CA Mutation/PTEN Expression Status Predicts Response of Colon Cancer Cells to the Epidermal Growth Factor Receptor Inhibitor Cetuximab
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Includes: Supplementary data
Journal Articles

Molecular determinants of response of colon cancer cells to histone deacetylase (HDAC) inhibitors.

John Mariadason, Shannon Nasser, Do-Sun Byun, Diego Arango, Minaxi Jhawer, Naseem Ahmed, Helena Smartt, Lucas Murray, Courtney Nicholas, Georgia Corner, Andrew Wilson, Leonard Augenlicht
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2479.
Published: 01 May 2007
View article titled, Molecular determinants of response of colon cancer cells to histone deacetylase (HDAC) inhibitors.
Journal Articles

The impact of HDAC2 mutations in the gene expression profile of human tumors

Santiago Ropero, Esteban Ballestar, Mario Fraga, Miguel Alaminos, Richard Hamelin, Hiroyuki Yamamoto, Diego Arango, Torben Orntoft, Lauri Aaltonen, Simo Schwartz, Manel Esteller
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4147.
Published: 01 May 2007
View article titled, The impact of HDAC2 mutations in the gene expression profile of human tumors
Journal Articles

EPHB4 and Survival of Colorectal Cancer Patients

Veronica Davalos, Higinio Dopeso, Julio Castaño, Andrew J. Wilson, Felip Vilardell, Jordi Romero-Gimenez, Eloy Espín, Manel Armengol, Gabriel Capella, John M. Mariadason, Lauri A. Aaltonen, Simo Schwartz, Jr., Diego Arango
Journal: Cancer Research
Cancer Res (2006) 66 (18): 8943–8948.
https://doi.org/10.1158/0008-5472.CAN-05-4640
Published: 18 September 2006
View article titled, EPHB4 and Survival of Colorectal Cancer Patients
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Includes: Supplementary data
Journal Articles

Fumarate hydratase-deficient uerine fibroids; a distinct gene expression profile

Sakari Vanharanta, Patrick J. Pollard, Heli J. Lehtonen, Päivi Laiho, Jari Sjöberg, Arto Leminen, Kristiina Aittomäki, Johanna Arola, Mogens Kruhoffer, Torben F. Ørntoft, Ian P. Tomlinson, Maija Kiuru, Diego Arango, Lauri A. Aaltonen
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 199–200.
Published: 15 April 2006
View article titled, Fumarate hydratase-deficient uerine fibroids; a distinct gene expression profile
Journal Articles

Histone deacetylase 4 is downregulated in intestinal epithelial cell maturation and represses p21

Andrew J. Wilson, Do-Sun Byun, Diego Arango, Lucas Murray, Leonard Augenlicht, John Mariadason
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 636.
Published: 15 April 2006
View article titled, Histone deacetylase 4 is downregulated in intestinal epithelial cell maturation and represses p21
Journal Articles

Mechanisms of Inactivation of the Receptor Tyrosine Kinase EPHB2 in Colorectal Tumors

Hafid Alazzouzi, Veronica Davalos, Antti Kokko, Enric Domingo, Stefan M. Woerner, Andrew J. Wilson, Lars Konrad, Päivi Laiho, Eloi Espín, Manel Armengol, Kohzoh Imai, Hiroyuki Yamamoto, John M. Mariadason, Johannes F. Gebert, Lauri A. Aaltonen, Simo Schwartz, Jr., Diego Arango
Journal: Cancer Research
Cancer Res (2005) 65 (22): 10170–10173.
https://doi.org/10.1158/0008-5472.CAN-05-2580
Published: 15 November 2005
View article titled, Mechanisms of Inactivation of the Receptor Tyrosine Kinase EPHB2 in Colorectal Tumors
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Includes: Supplementary data
Journal Articles

Mutations in Two Short Noncoding Mononucleotide Repeats in Most Microsatellite-Unstable Colorectal Cancers

Tuija Hienonen, Heli Sammalkorpi, Susa Enholm, Pia Alhopuro, Thomas D. Barber, Rainer Lehtonen, Nina N. Nupponen, Heli Lehtonen, Reijo Salovaara, Jukka-Pekka Mecklin, Heikki Järvinen, Riitta Koistinen, Diego Arango, Virpi Launonen, Bert Vogelstein, Auli Karhu, Lauri A. Aaltonen
Journal: Cancer Research
Cancer Res (2005) 65 (11): 4607–4613.
https://doi.org/10.1158/0008-5472.CAN-05-0165
Published: 01 June 2005
View article titled, Mutations in Two Short Noncoding Mononucleotide Repeats in Most Microsatellite-Unstable Colorectal Cancers
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