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Diansheng Zhong
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Journal Articles

Abstract CT053: Exploration of potential biomarkers correlated with efficacy of ociperlimab (anti-TIGIT) plus tislelizumab (anti-PD-1) in 1L PD-L1+ non-small cell lung cancer (NSCLC)

Se Hyun Kim, Jiayuan Zhang, Wei Tan, Han Yan, Tian Tian, Hao Zheng, Ziqi Zhou, Ruihua Wang, Yun Zhang, Zhirong Shen, Hye Ryun Kim, Diansheng Zhong, Shun Lu
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT053.
https://doi.org/10.1158/1538-7445.AM2024-CT053
Published: 05 April 2024
View article titled, Abstract CT053: Exploration of potential biomarkers correlated with efficacy of ociperlimab (anti-TIGIT) plus tislelizumab (anti-PD-1) in 1L PD-L1+ non-small cell lung cancer (NSCLC)
Journal Articles

Abstract CT255: AdvanTIG-204: A phase 2, multicenter, randomized, 3-arm, open-label study investigating the preliminary efficacy and safety of ociperlimab (anti-TIGIT) + tislelizumab (anti-PD-1) + concurrent chemoradiotherapy (cCRT) in patients with untreated limited-stage small cell lung cancer (SCLC)

Youling Gong, Qingsong Pang, Rong Yu, Zhengfei Zhu, Jiangqiong Huang, Yufeng Cheng, Diansheng Zhong, Hongbo Wu, Seung Soo Yoo, Tracy Dobbs, Zinan Bao, Yunxia Zuo, Boxian Wei, Pu Sun, You Lu
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT255.
https://doi.org/10.1158/1538-7445.AM2024-CT255
Published: 05 April 2024
View article titled, Abstract CT255: AdvanTIG-204: A phase 2, multicenter, randomized, 3-arm, open-label study investigating the preliminary efficacy and safety of ociperlimab (anti-TIGIT) + tislelizumab (anti-PD-1) + concurrent chemoradiotherapy (cCRT) in patients with untreated limited-stage small cell lung cancer (SCLC)
Journal Articles

Abstract CT152: A multicenter Phase II study of savolitinib in patients with MET-amplified gastroesophogeal junction adenocarcinomas or gastric cancer

Zhi Peng, Hua Wang, Baorui Liu, Huiting Xu, Zhenyang Liu, Tianshu Liu, Jun Zhang, Yuxian Bai, Ying Yuan, Tao Wu, Feng Ye, Qinghua Pan, Jufeng Wang, Enxiao Li, Diansheng Zhong, Yueyin Pan, Yanru Qin, Yan Yang, Yusheng Wang, Aiping Zhou, Yongshun Chen, Dianbao Zhang, Hongli Liu, Xiujuan Qu, Shubin Wang, Ning Liu, Jinsheng Wu, Wei Li, Kejun Nan, Hongming Pan, Jianming Xu, Chunmei Bai, Heling Liu, Jia Wei, Runzhi Chen, Rongrong Li, Wei Li, Jinghong Zhou, Hongyan Yin, Qian Xu, Songhua Fan, Yongxin Ren, Weiguo Su, Lin Shen
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT152.
https://doi.org/10.1158/1538-7445.AM2023-CT152
Published: 14 April 2023
View article titled, Abstract CT152: A multicenter Phase II study of savolitinib in patients with MET-amplified gastroesophogeal junction adenocarcinomas or gastric cancer
Journal Articles

Abstract CT034: Phase II study of SCC244 in NSCLC patients harboring MET exon 14 skipping (METex14) mutations (GLORY study)

Shun Lu, Yongfeng Yu, Jianya Zhou, Koichi Goto, Xingya Li, Jun Sakakibara-Konishi, Kazumi Nishino, Tanaka Kentaro, Lin Wu, Xuhong Min, Wei Zhang, Dingzhi Huang, Yongqian Shu, Chengzhi Zhou, Min Li, Xiaorong Dong, Chong Bai, Lu Li, Jiuwei Cui, Li Zhang, Lejie Cao, Xiaoling Li, AiMin Zang, Haruki Kobayashi, Yiping Zhang, Yan Yu, Xiuwen Wang, Terufumi Kato, Shoichiro Yamamoto, Yuki Shinno, Xiaoyan Lin, Yanqiu Zhao, Yanping Hu, Qitao Yu, Ziping Wang, Masahiro Kodani, Jian Fang, Jialei Wang, Meiqi Shi, Diansheng Zhong, Wen Dong, Hiroshi Tanaka, Yasuto Yoneshima, Minghui Sun, Jun Zhou, Qiuxia Wu, Meng Li
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT034.
https://doi.org/10.1158/1538-7445.AM2022-CT034
Published: 15 June 2022
View article titled, Abstract CT034: Phase II study of SCC244 in NSCLC patients harboring MET exon 14 skipping (METex14) mutations (GLORY study)
Journal Articles

Abstract 5231: Case report: dramatic response to Crizotinib in a patient with synchronous multiple primary lung cancer positive for a novel ARL1-MET fusion

Qing Ma, Lingping Kong, Diansheng Zhong
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5231.
https://doi.org/10.1158/1538-7445.AM2022-5231
Published: 15 June 2022
View article titled, Abstract 5231: Case report: dramatic response to Crizotinib in a patient with synchronous multiple primary lung cancer positive for a novel <em>ARL1-MET</em> fusion
Journal Articles

Abstract 374: NGS based profiling of homologous recombination genes to predict response to platinum-based chemotherapy in NSCLC

Linlin Zhang, Xin Wang, Hui Song, Fanlu Meng, Guowei Yu, Diansheng Zhong
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 374.
https://doi.org/10.1158/1538-7445.AM2021-374
Published: 01 July 2021
View article titled, Abstract 374: NGS based profiling of homologous recombination genes to predict response to platinum-based chemotherapy in NSCLC
Journal Articles

Abstract 403: The landscape of PD-L1 expression in lung cancer harboring EGFR mutations

Linlin Zhang, Fuyu Gong, Fanlu Meng, Xin Wang, DianSheng Zhong
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 403.
https://doi.org/10.1158/1538-7445.AM2021-403
Published: 01 July 2021
View article titled, Abstract 403: The landscape of PD-L1 expression in lung cancer harboring EGFR mutations
Journal Articles

Abstract 4770: The regulation of pre-ribosomal RNA synthesis by LKB1

Rui Jin, Faken Liu, Xiuju Liu, Henry Huang, Scott C. Wilkinson, Diansheng Zhong, Fadlo R. Khuri, Haian Fu, Adam I. Marcus, Yulong He, Wei Zhou
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4770.
https://doi.org/10.1158/1538-7445.AM2016-4770
Published: 15 July 2016
View article titled, Abstract 4770: The regulation of pre-ribosomal RNA synthesis by LKB1
Journal Articles

Abstract 1975: AICAR induces cell death in LKB1-deficient NSCLC.

Fakeng Liu, Wei Zhou, Xiuju Liu, Shi-yong Sun, Fadlo Khuri, Yu-long He, Diansheng Zhong
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1975.
https://doi.org/10.1158/1538-7445.AM2013-1975
Published: 15 April 2013
View article titled, Abstract 1975: AICAR induces cell death in LKB1-deficient NSCLC.
Journal Articles

Abstract 1058: LKB1 negatively regulates IGF-1 induced ERK phosphorylation

Diansheng Zhong, Xiuju Liu, Haian Fu, Shi-Yong Sun, Fadlo R. Khuri, Wei Zhou
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1058.
https://doi.org/10.1158/1538-7445.AM2011-1058
Published: 15 April 2011
View article titled, Abstract 1058: LKB1 negatively regulates IGF-1 induced ERK phosphorylation
Journal Articles

Abstract #5332: Adiponectin-mediated inhibition of metastatic properties of breast cancer cells involves upregulation of tumor suppressor gene, LKB1 and modulation of AMPK-S6K axis.

LaTonia Taliaferro-Smith, Arumugam Nagalingam, Diansheng Zhong, Wei Zhou, Brandi Knight, Elaine Oberlick, Neeraj Saxena, Dipali Sharma
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 5332.
Published: 01 May 2009
View article titled, Abstract #5332: Adiponectin-mediated inhibition of metastatic properties of breast cancer cells involves upregulation of tumor suppressor gene, LKB1 and modulation of AMPK-S6K axis.
Journal Articles

Abstract #4386: Phospho-proteomic analysis reveals the activation of ERK signaling by 2-deoxyglucose in NSCLC

Diansheng Zhong, Li Xiong, Tongrui Liu, Xiuju Liu, Jing Chen, Wei Zhou
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4386.
Published: 01 May 2009
View article titled, Abstract #4386: Phospho-proteomic analysis reveals the activation of ERK signaling by 2-deoxyglucose in NSCLC
Journal Articles

LKB1 Is Necessary for Akt-Mediated Phosphorylation of Proapoptotic Proteins

Diansheng Zhong, Xiuju Liu, Fadlo R. Khuri, Shi-Yong Sun, Paula M. Vertino, Wei Zhou
Journal: Cancer Research
Cancer Res (2008) 68 (18): 7270–7277.
https://doi.org/10.1158/0008-5472.CAN-08-1484
Published: 14 September 2008
View article titled, LKB1 Is Necessary for Akt-Mediated Phosphorylation of Proapoptotic Proteins
Open the PDF for LKB1 Is Necessary for Akt-Mediated Phosphorylation of Proapoptotic Proteins in another window
Includes: Supplementary data
Journal Articles

2-deoxyglucose induces Akt phosphorylation via a mechanism independent of LKB1/AMPK signaling activation or glycolysis inhibition

Diansheng Zhong, Xiuju Liu, Katherine Schafer-Hales, Adam Marcus, Fadlo Khuri, Shi-Yong Sun, Wei Zhou
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4348.
Published: 01 May 2008
View article titled, 2-deoxyglucose induces Akt phosphorylation via a mechanism independent of LKB1/AMPK signaling activation or glycolysis inhibition
Journal Articles

Somatic hypermethylation of Sox7 in prostate cancers

Lizheng Guo, Diansheng Zhong, Xiuju Liu, Xue-Yuan Dong, Xiaodong Sun, Paula Vertino, Carlos Moreno, Jing-Tang Dong, Wei Zhou
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): LB-62.
Published: 01 May 2007
View article titled, Somatic hypermethylation of Sox7 in prostate cancers
Journal Articles

FOXO3a phosphorylation at threonine32 requires both Akt and LKB1 in NSCLC cell lines

Diansheng Zhong, Xiuju Liu, Shi-Yong Sun, Paula M. Vertino, Wei Zhou
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 280.
Published: 01 May 2007
View article titled, FOXO3a phosphorylation at threonine32 requires both Akt and LKB1 in NSCLC cell lines
Journal Articles

Homozygous deletion of LKB1 mutation in H157 lung cancer cell line

Diansheng Zhong, Lizheng Guo, Itziar de Aguirre, Xiuju Liu, Neil Lamb, Shiyong Sun, Anthony Gal, Paula M Vertino, Wei Zhou
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 49.
Published: 15 April 2006
View article titled, Homozygous deletion of LKB1 mutation in H157 lung cancer cell line
Journal Articles

Anti-HIF Activity of curcumin and analog EF24.

Shala L. Thomas, Aurora M. O’Brate, Sanna Malik, Diansheng Zhong, Wei Zhou, James P. Snyder, Dennis Liotta, Paraskevi Giannakakou
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1348–1349.
Published: 15 April 2006
View article titled, Anti-HIF Activity of curcumin and analog EF24.
Journal Articles

Homozygous deletion of MAHD4 in infiltrative ductal breast carcinomas

Diansheng Zhong, Aki Morikawa, Michael Guo, Cecile Colpaert, Li Xiong, Neil Lamb, Ceshi Chen, Jin-Tang Dong, Wei Zhou
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 443–444.
Published: 01 May 2005
View article titled, Homozygous deletion of <em>MAHD4</em> in infiltrative ductal breast carcinomas