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Derek C. Radisky
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Journal Articles

Abstract 187: STAT1 and GBP1 promote proliferation in postpartum breast epithelium by downregulating cyclin-dependent kinase inhibitors: implications for increased postpartum breast cancer risk

Free
Joshua Ogony, Melody Stallings-Mann, Sarah McLaughlin, Mark Sherman, Derek C. Radisky
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 187.
https://doi.org/10.1158/1538-7445.AM2025-187
Published: 21 April 2025
View articletitled, Abstract 187: STAT1 and GBP1 promote proliferation in postpartum breast epithelium by downregulating cyclin-dependent kinase inhibitors: implications for increased postpartum breast cancer risk
Journal Articles

Abstract 5115: Engineered TIMP-1 for selective MMP-9 inhibition: A novel strategy to suppress breast cancer invasiveness

Free
Alireza Shoari, Alexandra Hockla, Mathew A. Coban, Alexandra M. Dimesa, Derek C. Radisky, Evette S. Radisky
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5115.
https://doi.org/10.1158/1538-7445.AM2025-5115
Published: 21 April 2025
View articletitled, Abstract 5115: Engineered TIMP-1 for selective MMP-9 inhibition: A novel strategy to suppress breast cancer invasiveness
Journal Articles

Abstract 1912: Immune and molecular markers in benign breast disease predict risk of node-positive breast cancer

Free
Matilde Rossi, Nicole Cruz-Reyes, Trista Navarro, Melody L. Stallings-Mann, Bryan M. McCauley, Robert A. Vierkant, Stacey J. Winham, Mark E. Sherman, Amy C. Degnim, Derek C. Radisky
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1912.
https://doi.org/10.1158/1538-7445.AM2025-1912
Published: 21 April 2025
View articletitled, Abstract 1912: Immune and molecular markers in benign breast disease predict risk of node-positive breast cancer
Journal Articles

Abstract LB328: Measurement of ER and Ki67 coexpression in cytokeratin positive epithelial cells in benign breast disease (BBD) percutaneous biopsies

Free
Melody L. Stallings-Mann, Robert A. Vierkant, Stacey J. Winham, Bryan McCauley, Matt R. Jensen, Sophie Noel, Laura Pacheco-Spann, Celine M. Vachon, Amy C. Degnim, Derek C. Radisky, Mark E. Sherman
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB328.
https://doi.org/10.1158/1538-7445.AM2024-LB328
Published: 05 April 2024
View articletitled, Abstract LB328: Measurement of ER and Ki67 coexpression in cytokeratin positive epithelial cells in benign breast disease (BBD) percutaneous biopsies
Journal Articles

Abstract 283: Fibroblast diversity and immune microenvironment in pseudoangiomatous stromal hyperplasia (PASH): Associations with breast cancer risk

Free
Nicole Cruz-Reyes, Matilde Rossi, Melody Stallings Mann, Bryan McCauley, Tanya Hoskin, Robert Vierkant, Stacey Winham, Amy Degnim, Mark E. Sherman, Derek C. Radisky
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 283.
https://doi.org/10.1158/1538-7445.AM2024-283
Published: 22 March 2024
View articletitled, Abstract 283: Fibroblast diversity and immune microenvironment in pseudoangiomatous stromal hyperplasia (PASH): Associations with breast cancer risk
Journal Articles

Abstract 4773: Interferon regulatory factor 8 (IRF8) as a biomarker for early detection and prevention of axillary lymph node-positive breast cancer

Free
Matilde Rossi, Nicole Cruz-Reyes, Melody L. Stallings Mann, Bryan M. McCauley, Tanya L. Hoskin, Robert A. Vierkant, Stacey J. Winham, Amy C. Degnim, Mark E. Sherman, Derek C. Radisky
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4773.
https://doi.org/10.1158/1538-7445.AM2024-4773
Published: 22 March 2024
View articletitled, Abstract 4773: Interferon regulatory factor 8 (IRF8) as a biomarker for early detection and prevention of axillary lymph node-positive breast cancer
Journal Articles

Abstract 2139: Identifying molecular mechanisms in triple negative breast cancer disparities: Unveiling the role of Hedgehog signaling in non-Hispanic Black women

Free
Jennifer Vanessa Cabezas, Savanna Touré, Matthew Wilson, Melody L. Stallings Mann, Laura M. Pacheco-Spann, Joshua W. Ogony, Mark E. Sherman, Derek C. Radisky
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2139.
https://doi.org/10.1158/1538-7445.AM2024-2139
Published: 22 March 2024
View articletitled, Abstract 2139: Identifying molecular mechanisms in triple negative breast cancer disparities: Unveiling the role of Hedgehog signaling in non-Hispanic Black women
Journal Articles

Abstract 1000: Associations of parity and body mass index with NanoString digital spatial protein profiling in early onset breast cancer

Free
Robert A. Vierkant, Laura M. Pacheco-Spann, Stacey J. Winham, Jennifer M. Kachergus, Ji Shi, Craig Snow, Fergus J. Couch, Janet E. Olson, Chen Wang, Derek C. Radisky, Amy C. Degnim, E. Aubrey Thompson, Laura C. Collins, Kathryn J. Ruddy, Ann H. Partridge, Mark E. Sherman
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1000.
https://doi.org/10.1158/1538-7445.AM2023-1000
Published: 04 April 2023
View articletitled, Abstract 1000: Associations of parity and body mass index with NanoString digital spatial protein profiling in early onset breast cancer
Journal Articles

Abstract 4291: Deconvolution of cell type composition in FFPE tissue: Application to benign breast disease

Free
Yuanhang Liu, Chen Wang, Stacey J. Winham, Aditya Bhagwate, Robert A. Vierkant, Julie M. Cunningham, Bryan M. McCauley, William A. Jons, Derek C. Radisky, Amy C. Degnim
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4291.
https://doi.org/10.1158/1538-7445.AM2023-4291
Published: 04 April 2023
View articletitled, Abstract 4291: Deconvolution of cell type composition in FFPE tissue: Application to benign breast disease
Journal Articles

Abstract 2203: Towards prediction of breast cancer risk in benign biopsies with high-plex GeoMx spatial protein profiling

Free
Robert Alan Vierkant, Jodi M. Carter, Stacey J. Winham, Chen Wang, Jennifer M. Kachergus, Ji Shi, Raymond M. Moore, Bryan M. McCauley, Laura M. Pacheco-Spann, E A. Thompson, Derek C. Radisky, Amy C. Degnim, Mark E. Sherman
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2203.
https://doi.org/10.1158/1538-7445.AM2022-2203
Published: 15 June 2022
View articletitled, Abstract 2203: Towards prediction of breast cancer risk in benign biopsies with high-plex GeoMx spatial protein profiling
Journal Articles

Abstract 6333: Quantification of oxylipins as biomarkers of inflammation and cancer risk in breast tissue

Free
Ginger L. Milne, Robert A. Vierkant, Amy C. Degnim, Anna Maria Storniolo, Jill E. Henry, Laura M. Pacheco-Spann, Derek C. Radisky, Mark E. Sherman
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6333.
https://doi.org/10.1158/1538-7445.AM2022-6333
Published: 15 June 2022
View articletitled, Abstract 6333: Quantification of oxylipins as biomarkers of inflammation and cancer risk in breast tissue
Journal Articles

Abstract 5947: Immune biomarkers in breast tissues of patients with BRCA1/2 mutations, benign breast disease, and normal tissue donors

Free
Joshua W. Ogony, Tanya L. Hoskin, Melody L. Stallings Mann, Stacey J. Winham, Rushin Brahmbhatt, Muhammad Asad Arshad, Alvaro Pena Jimenez, Teresa M. Allers, Mark E. Sherrman, Daniel W. Visscher, Derek C. Radisky, Amy C. Degnim
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5947.
https://doi.org/10.1158/1538-7445.AM2022-5947
Published: 15 June 2022
View articletitled, Abstract 5947: Immune biomarkers in breast tissues of patients with BRCA1/2 mutations, benign breast disease, and normal tissue donors
Journal Articles

Abstract 2515: MMP1 and TGF-β1 cooperate to drive tumor progression in large cell carcinoma of the lung through fibroblast senescence

Free
Marta Gabasa, Evette S. Radisky, Rafael Ikemori, Giulia Bertolini, Marselina Arshakyan, Alexandra Hockla, Paula Duch, Ornella Rondinone, Alejandro Llorente, Maria Maqueda, Alexandre Perera, Noemí Reguart, Luca Roz, Derek C. Radisky, Jordi Alcaraz
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2515.
https://doi.org/10.1158/1538-7445.AM2021-2515
Published: 01 July 2021
View articletitled, Abstract 2515: MMP1 and TGF-β1 cooperate to drive tumor progression in large cell carcinoma of the lung through fibroblast senescence
Journal Articles

Abstract 2274: Somatic variant burdenin benign breast disease and association with risk of subsequent breast cancer

Free
Stacey J. Winham, Julie M. Cunningham, Yuanhang Liu, Aditya V. Bhagwate, Ethan P. Heinzen, Samantha J. McDonough, Melody L. Stallings-Mann, Robert A. Vierkant, Jodi M. Carter, Mark E. Sherman, Derek C. Radisky, Amy C. Degnim, Chen Wang
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2274.
https://doi.org/10.1158/1538-7445.AM2021-2274
Published: 01 July 2021
View articletitled, Abstract 2274: Somatic variant burdenin benign breast disease and association with risk of subsequent breast cancer
Journal Articles

Enhanced Antitumor Immunity via Endocrine Therapy Prevents Mammary Tumor Relapse and Increases Immune Checkpoint Blockade Sensitivity

Available to Purchase
Gonzalo R. Sequeira, Ana Sahores, Tomás Dalotto-Moreno, Ramiro M. Perrotta, Gabriela Pataccini, Silvia I. Vanzulli, María L. Polo, Derek C. Radisky, Carol A. Sartorius, Virginia Novaro, Caroline A. Lamb, Gabriel A. Rabinovich, Mariana Salatino, Claudia Lanari
Journal: Cancer Research
Cancer Res (2021) 81 (5): 1375–1387.
https://doi.org/10.1158/0008-5472.CAN-20-1441
Published: 01 March 2021
View articletitled, Enhanced Antitumor Immunity via Endocrine Therapy Prevents Mammary Tumor Relapse and Increases Immune Checkpoint Blockade Sensitivity
Open the PDF for Enhanced Antitumor Immunity via Endocrine Therapy Prevents Mammary Tumor Relapse and Increases Immune Checkpoint Blockade Sensitivity in another window
Includes: Supplementary data
Journal Articles

Abstract PS7-11: Benign breast disease: Temporal trends from 1967 to 2013

Free
Amy Degnim, Karthik Ghosh, Jodi M Carter, Robert A Vierkant, Matthew R Jensen, Stacey J Winham, Tanya L Hoskin, Marlene Frost, Teresa M Allers, Denise L Gehling, Mindy J Kern, Laura M Pacheco-Spann, Celine M Vachon, Derek C Radisky, Daniel W Visscher, Mark E Sherman
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS7-11.
https://doi.org/10.1158/1538-7445.SABCS20-PS7-11
Published: 15 February 2021
View articletitled, Abstract PS7-11: Benign breast disease: Temporal trends from 1967 to 2013
Journal Articles

Abstract PD10-10: Epithelial proliferation score as an independent breast cancer risk predictor in benign breast disease

Free
Jodi M Carter, Matthew R Jensen, Robert A Vierkant, Stacey J Winham, Tanya L Hoskin, Marlene Frost, Karthik Ghosh, Derek C Radisky, Amy C Degnim, Mark E Sherman
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PD10-10.
https://doi.org/10.1158/1538-7445.SABCS20-PD10-10
Published: 15 February 2021
View articletitled, Abstract PD10-10: Epithelial proliferation score as an independent breast cancer risk predictor in benign breast disease
Journal Articles

Abstract 2113: Discrimination of benign breast disease from normal lobules using an automated computational pathology algorithm

Free
Amy C. Degnim, Thomas de Bel, Mark E. Sherman, Derek C. Radisky, Stacey J. Winham, Tanya L. Hoskin, Melody L. Stallings Mann, Marlene Frost, Robert A. Vierkant, Brendan T. Broderick, Ethan P. Heinzen, Rushin Brahmbhatt, Muhammad Arshad, Celine M. Vachon, Jodi M. Carter, Lori A. Denison, Daniel W. Visscher, Jeroen van der Laak
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2113.
https://doi.org/10.1158/1538-7445.AM2020-2113
Published: 15 August 2020
View articletitled, Abstract 2113: Discrimination of benign breast disease from normal lobules using an automated computational pathology algorithm
Journal Articles

Abstract 4635: Analysis of post-partum breast tissue to understand early onset breast cancer

Free
Joshua Ogony, DereK C. Radisky, Amy C. Degnim, Marlene Frost, Tanya L. Hoskin, Michael G. Heckman, Launia J. White, Mark E. Sherman
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4635.
https://doi.org/10.1158/1538-7445.AM2020-4635
Published: 15 August 2020
View articletitled, Abstract 4635: Analysis of post-partum breast tissue to understand early onset breast cancer
Journal Articles

Abstract 3758: Targeting ovarian cancer induced peritoneal carcinomatosis by inhibition of signaling axis between Interleukin-6 (IL-6) and serine protease inhibitor Kazal type 1 (SPINK1)

Free
Christine Mehner, Erin Miller, Mathew A. Coban, Alexandra Hockla, Derek C. Radisky, Evette S. Radisky
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3758.
https://doi.org/10.1158/1538-7445.AM2019-3758
Published: 01 July 2019
View articletitled, Abstract 3758: Targeting ovarian cancer induced peritoneal carcinomatosis by inhibition of signaling axis between Interleukin-6 (IL-6) and serine protease inhibitor Kazal type 1 (SPINK1)