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Denise Corti
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Journal Articles

Abstract 2900: Dissection of clonal heterogeneity unmasks pre-existing chemoresistance and new metabolic vulnerabilities in pancreatic cancer

Sahil Seth, Chieh-Yuan Li, Sara Loponte, I-Lin Ho, Denise Corti, Luigi Sapio, Edoardo Del Poggetto, Michael Peoples, Tatiana Karpinets, Frederick S. Robinson, Shan Jiang, Prasanta Dutta, Joseph Marszalek, Maria E. Di Francesco, Timothy P. Heffernan, Virginia Giuliani, Pratip K. Bhattacharya, Giannicola Genovese, Andrew Futreal, Giulio Draetta, Andrea Viale, Alessandro Carugo
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2900.
https://doi.org/10.1158/1538-7445.AM2019-2900
Published: 01 July 2019
View article titled, Abstract 2900: Dissection of clonal heterogeneity unmasks pre-existing chemoresistance and new metabolic vulnerabilities in pancreatic cancer
Journal Articles

Abstract 2856: Targeting OXPHOS with IACS-010759 to eliminate standard of care resistant tumor cells

Joseph R. Marszalek, Sahil Seth, Denise Corti, Qi Zhang, Gloria V. Echeverria, Lina Han, Yuting Sun, Jennifer Molina, Sonal Gera, Edward Chang, Tin O. Khor, Mikhila Mahendra, Ningping Feng, Jason P. Gay, Timothy McAfoos, Virginia Giuliani, Xi Shi, Sabrina Jeter-Jones, Sarah Loponte, Chieh-Yuan Li, Christopher A. Bristow, Maria Emilia Di Francesco, Helen Piwnica-Worms, Marina Konopleva, Alessandro Carugo, Andrea Viale, Philip Jones, Timothy P. Heffernan, Giulio F. Draetta
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2856.
https://doi.org/10.1158/1538-7445.AM2018-2856
Published: 01 July 2018
View article titled, Abstract 2856: Targeting OXPHOS with IACS-010759 to eliminate standard of care resistant tumor cells
Journal Articles

Abstract 4953: Metabolic targeting of chemoresistance perturbs clonal complexity in pancreatic cancer

Sara Loponte, Denise Corti, Sahil Seth, Edoardo Del Poggetto, I-Lin Ho, Chieh-Yuan Li, Shan Jiang, Joseph R. Marszalek, Maria Emilia Di Francesco, Giannicola Genovese, Giulio Draetta, Alessandro Carugo, Andrea Viale
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4953.
https://doi.org/10.1158/1538-7445.AM2018-4953
Published: 01 July 2018
View article titled, Abstract 4953: Metabolic targeting of chemoresistance perturbs clonal complexity in pancreatic cancer
Journal Articles

Abstract 1177: Clonal dissection of pancreatic tumors unmasks functional and genomic heterogeneous long-term self-renewing compartments at the origin of treatment resistance

Sahil Seth, Chieh-Yuan Li, I-Lin Ho, Denise Corti, Sara Loponte, Luigi Sapio, Edoardo Del Poggetto, Michael Peoples, Tatiana Karpinets, Giannicola Genovese, Andrew Futreal, Giulio Draetta, Alessandro Carugo, Andrea Viale
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1177.
https://doi.org/10.1158/1538-7445.AM2018-1177
Published: 01 July 2018
View article titled, Abstract 1177: Clonal dissection of pancreatic tumors unmasks functional and genomic heterogeneous long-term self-renewing compartments at the origin of treatment resistance
Journal Articles

Abstract A15: Generation of clonal replica tumors to interrogate complexity of human cancer in vivo

Sahil Seth, Chieh-Yuan Li, Denise Corti, Sara Loponte, I-Lin Ho, Edoardo Del Poggetto, Michael Peoples, Christopher Bristow, Joseph Marszalek, Timothy Heffernan, Giannicola Genovese, Giulio Draetta, Alessandro Carugo, Andrea Viale
Journal: Cancer Research
Cancer Res (2018) 78 (10_Supplement): A15.
https://doi.org/10.1158/1538-7445.MOUSEMODELS17-A15
Published: 14 May 2018
View article titled, Abstract A15: Generation of clonal replica tumors to interrogate complexity of human cancer in vivo
Journal Articles

Tumors and Mitochondrial Respiration: A Neglected Connection

Andrea Viale, Denise Corti, Giulio F. Draetta
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (18): 3687–3691.
https://doi.org/10.1158/0008-5472.CAN-15-0491
Published: 14 September 2015
View article titled, Tumors and Mitochondrial Respiration: A Neglected Connection
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Journal Articles

Abstract 976: Metabolic eradication of treatment resistant cancer stem cells in pancreatic tumors: A clonal tracking-based platform for identifying the best personalized treatment

Denise Corti, Alessandro Carugo, Seth Sahil, Matteo Marchesini, Piergiorgio Pettazzoni, Luigi Nezi, Tessa Green, Joseph R Marszalek, Maria Emilia Di Francesco, Timothy P Heffernan, Giulio F Draetta, Andrea Viale
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 976.
https://doi.org/10.1158/1538-7445.AM2015-976
Published: 01 August 2015
View article titled, Abstract 976: Metabolic eradication of treatment resistant cancer stem cells in pancreatic tumors: A clonal tracking-based platform for identifying the best personalized treatment
Journal Articles

Genetic Events That Limit the Efficacy of MEK and RTK Inhibitor Therapies in a Mouse Model of KRAS-Driven Pancreatic Cancer

Piergiorgio Pettazzoni, Andrea Viale, Parantu Shah, Alessandro Carugo, Haoqiang Ying, Huamin Wang, Giannicola Genovese, Sahil Seth, Rosalba Minelli, Tessa Green, Emmet Huang-Hobbs, Denise Corti, Nora Sanchez, Luigi Nezi, Matteo Marchesini, Avnish Kapoor, Wantong Yao, Maria E. Di Francesco, Alessia Petrocchi, Angela K. Deem, Kenneth Scott, Simona Colla, Gordon B. Mills, Jason B. Fleming, Timothy P. Heffernan, Philip Jones, Carlo Toniatti, Ronald A. DePinho, Giulio F. Draetta
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (6): 1091–1101.
https://doi.org/10.1158/0008-5472.CAN-14-1854
Published: 12 March 2015
View article titled, Genetic Events That Limit the Efficacy of MEK and RTK Inhibitor Therapies in a Mouse Model of KRAS-Driven Pancreatic Cancer
Open the PDF for Genetic Events That Limit the Efficacy of MEK and RTK Inhibitor Therapies in a Mouse Model of KRAS-Driven Pancreatic Cancer in another window
Includes: Supplementary data