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Abstract 2152: TNIK, a novel activator of FAK and YAP signaling, is a therapeutic target in lung squamous cell carcinoma

Pedro Torres-Ayuso, Elvira An, Katherine M. Nyswaner, Daniel A. Ritt, Suzanne I. Specht, Sudipto Das, Thorkell Andresson, Christina M. Robinson, Simone Difilippantonio, Baktiar O. Karim, Benjamin E. Turk, Deborah K. Morrison, John Brognard

Cancer Res (2022) 82 (12_Supplement): 2152.

DOI: https://doi.org/10.1158/1538-7445.AM2022-2152

Published: 15 June 2022

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Journal Articles

Oncogenic RAS-Induced Perinuclear Signaling Complexes Requiring KSR1 Regulate Signal Transmission to Downstream Targets

Sandip K. Basu, Sook Lee, Jacqueline Salotti, Srikanta Basu, Krisada Sakchaisri, Zhen Xiao, Vijay Walia, Christopher J. Westlake, Deborah K. Morrison, Peter F. Johnson

Cancer Res (2018) 78 (4): 891–908.

DOI: https://doi.org/10.1158/0008-5472.CAN-17-2353

Published: 14 February 2018

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Includes: Supplementary data

Journal Articles

KIT Suppresses BRAF^V600E-Mutant Melanoma by Attenuating Oncogenic RAS/MAPK Signaling

James V. Neiswender, Robert L. Kortum, Caitlin Bourque, Melissa Kasheta, Leonard I. Zon, Deborah K. Morrison, Craig J. Ceol

Cancer Res (2017) 77 (21): 5820–5830.

DOI: https://doi.org/10.1158/0008-5472.CAN-17-0473

Published: 31 October 2017

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Includes: Supplementary data

Journal Articles

Abstract A35: Oncogenic Ras signaling involves formation of perinuclear CK2α nd p-ERK1/2 signaling complexes that require the KSR-1 scaffold protein and endosomal trafficking

Sandip K. Basu, Sook Lee, Krisada Sakchaisri, Vijay Walia, Christopher J. Westlake, Deborah K. Morrison, Peter F. Johnson

Cancer Res (2016) 76 (3_Supplement): A35.

DOI: https://doi.org/10.1158/1538-7445.FBCR15-A35

Published: 07 April 2016

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Journal Articles

Abstract LB-108: Targeting the Ras-Binding domain of RAS effector proteins by a small molecule inhibitor, Rigosertib

SaiKrishna Divakar, Rodrigo Vasqez-Del Caprio, Stacey J. Baker, M.V. Ramana Reddy, Daniel A. Ritt, Deborah K. Morrison, E. Premkumar Reddy

Cancer Res (2014) 74 (19_Supplement): LB-108.

DOI: https://doi.org/10.1158/1538-7445.AM2014-LB-108

Published: 01 October 2014

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Journal Articles

Abstract 1239: Differential effects of dimerization on B-Raf and C-Raf function revealed by mutational analysis and peptide inhibitors that target the Raf dimer interface

Alyson K. Freeman, Daniel A. Ritt, Deborah K. Morrison

Cancer Res (2012) 72 (8_Supplement): 1239.

DOI: https://doi.org/10.1158/1538-7445.AM2012-1239

Published: 15 April 2012

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Abstract 2152: TNIK, a novel activator of FAK and YAP signaling, is a therapeutic target in lung squamous cell carcinoma

Oncogenic RAS-Induced Perinuclear Signaling Complexes Requiring KSR1 Regulate Signal Transmission to Downstream Targets

KIT Suppresses BRAF^V600E-Mutant Melanoma by Attenuating Oncogenic RAS/MAPK Signaling

Abstract A35: Oncogenic Ras signaling involves formation of perinuclear CK2α nd p-ERK1/2 signaling complexes that require the KSR-1 scaffold protein and endosomal trafficking

Abstract LB-108: Targeting the Ras-Binding domain of RAS effector proteins by a small molecule inhibitor, Rigosertib

Abstract 1239: Differential effects of dimerization on B-Raf and C-Raf function revealed by mutational analysis and peptide inhibitors that target the Raf dimer interface

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AACR Journals

Abstract 2152: TNIK, a novel activator of FAK and YAP signaling, is a therapeutic target in lung squamous cell carcinoma

Oncogenic RAS-Induced Perinuclear Signaling Complexes Requiring KSR1 Regulate Signal Transmission to Downstream Targets

KIT Suppresses BRAFV600E-Mutant Melanoma by Attenuating Oncogenic RAS/MAPK Signaling

Abstract A35: Oncogenic Ras signaling involves formation of perinuclear CK2α nd p-ERK1/2 signaling complexes that require the KSR-1 scaffold protein and endosomal trafficking

Abstract LB-108: Targeting the Ras-Binding domain of RAS effector proteins by a small molecule inhibitor, Rigosertib

Abstract 1239: Differential effects of dimerization on B-Raf and C-Raf function revealed by mutational analysis and peptide inhibitors that target the Raf dimer interface

Email alerts

AACR Journals

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KIT Suppresses BRAF^V600E-Mutant Melanoma by Attenuating Oncogenic RAS/MAPK Signaling