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David Sugarbaker
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Journal Articles

Abstract 4723: Macrophages foster neoplastic progression of malignant mesothelioma and limit response to chemotherapy.

Collin Blakely, Tina Bose, Melissa Wheeler, Raphael Bueno, David Sugarbaker, David Jablons, V. Courtney Broaddus, Lisa Coussens
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4723.
https://doi.org/10.1158/1538-7445.AM2013-4723
Published: 15 April 2013
View article titled, Abstract 4723: Macrophages foster neoplastic progression of malignant mesothelioma and limit response to chemotherapy.
Journal Articles

Abstract 454: Targeting macrophages in a preclinical model of malignant mesothelioma

Collin M. Blakely, Nikita Kolhatkar, Magnus Johansson, Adam Beltran, Dario Barbone, Raphael Bueno, David Sugarbaker, Thierry Jahan, David Jablons, V. Courtney Broaddus, Lisa M. Coussens
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 454.
https://doi.org/10.1158/1538-7445.AM2011-454
Published: 15 April 2011
View article titled, Abstract 454: Targeting macrophages in a preclinical model of malignant mesothelioma
Journal Articles

Abstract #1355: AXL is strongly activated and a potential target for therapeutic intervention in mesothelioma

Wen-bin Ou, Raphael Bueno, David Sugarbaker, Jonathan Fletcher
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1355.
Published: 01 May 2009
View article titled, Abstract #1355: AXL is strongly activated and a potential target for therapeutic intervention in mesothelioma
Journal Articles

Abstract #3017: Environmental exposures and aging are associated with tissue-specific alterations in DNA methylation at cancer-related CpG loci in normal tissues

Brock Christensen, E. Andres Houseman, Carmen Marsit, Shichun Zheng, Margaret Wrensch, Joseph Wiemels, Heather Nelson, Margaret Karagas, Raphael Bueno, David Sugarbaker, Ru-Fang Yeh, John Wiencke, Karl Kelsey
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3017.
Published: 01 May 2009
View article titled, Abstract #3017: Environmental exposures and aging are associated with tissue-specific alterations in DNA methylation at cancer-related CpG loci in normal tissues
Journal Articles

EML4-ALK fusion gene and sensitivity to an ALK kinase inhibitor in lung cancer

Jussi Koivunen, Craig Mermel, Kreshnik Zejnullahu, Carly Murphy, Alison Holmes, Hwan Geun Choi, Jhingook Kim, Derek Chiang, Jinseon Lee, William Richards, David Sugarbaker, Christopher Ducko, Neal Lindeman, J. Paul Marcoux, Nathanael Gray, Charles Lee, Matthew Meyerson, Pasi Janne
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2373.
Published: 01 May 2008
View article titled, EML4-ALK fusion gene and sensitivity to an ALK kinase inhibitor in lung cancer
Journal Articles

Methylation profiling of tumor and peripheral blood DNA in malignant pleural mesothelioma patients

Brock Christensen, E. Andres Houseman, Ru-Fang Yeh, John Godleski, Raphael Bueno, David Sugarbaker, Margaret Karagas, Margaret Wrensch, Joseph Wiemels, Shichun Zheng, Carmen Marsit, Heather Nelson, John Wiencke, Karl Kelsey
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 54.
Published: 01 May 2008
View article titled, Methylation profiling of tumor and peripheral blood DNA in malignant pleural mesothelioma patients
Journal Articles

Shotgun transcriptome sequencing of malignant pleural mesothelioma tumors to determine the mutational profile of individual patients

David Sugarbaker, William Richards, Gavin Gordon, Lingsheng Dong, Assunta DeRienzo, Gautam Maulik, Jonathan Glickman, Lucian Chirieac, Mor-Li Hartman, Bruce Taillon, Lei Du, Pascal Boufard, Stephen Kingsmore, Neil Miller, andrew Farmer, Roderick Jensen, Steven Gullans, Raphael Bueno
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1683.
Published: 01 May 2008
View article titled, Shotgun transcriptome sequencing of malignant pleural mesothelioma tumors to determine the mutational profile of individual patients
Journal Articles

Paxillin Is a Target for Somatic Mutations in Lung Cancer: Implications for Cell Growth and Invasion

Ramasamy Jagadeeswaran, Hanna Surawska, Soundararajan Krishnaswamy, Varalakshmi Janamanchi, A. Craig Mackinnon, Tanguy Y. Seiwert, Sivakumar Loganathan, Rajani Kanteti, Trevor Reichman, Vidya Nallasura, Stuart Schwartz, Leonardo Faoro, Yi-Ching Wang, Luc Girard, Maria S. Tretiakova, Salman Ahmed, Osvaldo Zumba, Lioubov Soulii, Vytas P. Bindokas, Livia L. Szeto, Gavin J. Gordon, Raphael Bueno, David Sugarbaker, Mark W. Lingen, Martin Sattler, Thomas Krausz, Wickii Vigneswaran, Viswanathan Natarajan, John Minna, Everett E. Vokes, Mark K. Ferguson, Aliya N. Husain, Ravi Salgia
Journal: Cancer Research
Cancer Res (2008) 68 (1): 132–142.
https://doi.org/10.1158/0008-5472.CAN-07-1998
Published: 02 January 2008
View article titled, Paxillin Is a Target for Somatic Mutations in Lung Cancer: Implications for Cell Growth and Invasion
Open the PDF for Paxillin Is a Target for Somatic Mutations in Lung Cancer: Implications for Cell Growth and Invasion in another window
Includes: Supplementary data
Journal Articles

Asbestos burden, epigenetic silencing, and survival in malignant pleural mesothelioma

Brock Christensen, Jennifer Longacker, Carmen Marsit, E Houseman, Heather Nelson, John Godleski, Raphael Bueno, David Sugarbaker, Karl Kelsey
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 817.
Published: 01 May 2007
View article titled, Asbestos burden, epigenetic silencing, and survival in malignant pleural mesothelioma
Journal Articles

Rapamycin increases sensitivity to cisplatin in mesothelioma cell lines

Mor-Li Hartman, John Esposito, Beow Yeap, David Sugarbaker
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): LB-310.
Published: 01 May 2007
View article titled, Rapamycin increases sensitivity to cisplatin in mesothelioma cell lines
Journal Articles

Frozen tumor specimen microaliquoting for precision histologic annotation

William G. Richards, S. Branden Van Oss, Harriet Mercer, Gavin Gordon, David Sugarbaker, Raphael Bueno, Jonathan Glickman
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 851.
Published: 15 April 2006
View article titled, Frozen tumor specimen microaliquoting for precision histologic annotation
Journal Articles

Homozygous Deletions and Chromosome Amplifications in Human Lung Carcinomas Revealed by Single Nucleotide Polymorphism Array Analysis

Xiaojun Zhao, Barbara A. Weir, Thomas LaFramboise, Ming Lin, Rameen Beroukhim, Levi Garraway, Javad Beheshti, Jeffrey C. Lee, Katsuhiko Naoki, William G. Richards, David Sugarbaker, Fei Chen, Mark A. Rubin, Pasi A. Jänne, Luc Girard, John Minna, David Christiani, Cheng Li, William R. Sellers, Matthew Meyerson
Journal: Cancer Research
Cancer Res (2005) 65 (13): 5561–5570.
https://doi.org/10.1158/0008-5472.CAN-04-4603
Published: 01 July 2005
View article titled, Homozygous Deletions and Chromosome Amplifications in Human Lung Carcinomas Revealed by Single Nucleotide Polymorphism Array Analysis
Open the PDF for Homozygous Deletions and Chromosome Amplifications in Human Lung Carcinomas Revealed by Single Nucleotide Polymorphism Array Analysis in another window
Includes: Supplementary data
Journal Articles

Role of c-Met and its mutated variants as therapeutic target using the small molecule inhibitor SU11274 and siRNA in non-small cell lung cancer

Patrick C. Ma, Ramasamy Jagadeeswaran, Sascha Dietrich, Simha Jagadeesh, Maria S. Tretiakova, Vidya Nallasura, Edward A. Fox, Alan Lader, William Richards, David Sugarbaker, Aliya N. Husain, James G. Christensen, Ravi Salgia
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 134–135.
Published: 01 May 2005
View article titled, Role of c-Met and its mutated variants as therapeutic target using the small molecule inhibitor SU11274 and siRNA in non-small cell lung cancer
Journal Articles

Functional Expression and Mutations of c-Met and Its Therapeutic Inhibition with SU11274 and Small Interfering RNA in Non–Small Cell Lung Cancer

Patrick C. Ma, Ramasamy Jagadeeswaran, Simha Jagadeesh, Maria S. Tretiakova, Vidya Nallasura, Edward A. Fox, Mark Hansen, Erik Schaefer, Katsuhiko Naoki, Alan Lader, William Richards, David Sugarbaker, Aliya N. Husain, James G. Christensen, Ravi Salgia
Journal: Cancer Research
Cancer Res (2005) 65 (4): 1479–1488.
https://doi.org/10.1158/0008-5472.CAN-04-2650
Published: 25 February 2005
View article titled, Functional Expression and Mutations of c-Met and Its Therapeutic Inhibition with SU11274 and Small Interfering RNA in Non–Small Cell Lung Cancer
Open the PDF for Functional Expression and Mutations of c-Met and Its Therapeutic Inhibition with SU11274 and Small Interfering RNA in Non–Small Cell Lung Cancer in another window
Journal Articles

c-MET expression/activation, functions, and mutations in non-small cell lung cancer

Patrick C. Ma, Simha Jagadeesh, Ramasamy Jagadeeswaran, Edward A. Fox, James Christensen, Gautam Maulik, Katsuhiko Naoki, Erik Schaefer, Alan Lader, William Richards, David Sugarbaker, Matthew Meyerson, Ravi Salgia
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 430–431.
Published: 01 April 2004
View article titled, c-MET expression/activation, functions, and mutations in non-small cell lung cancer