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Journal Articles

Targetable T-type Calcium Channels Drive Glioblastoma

Free
Ying Zhang, Nichola Cruickshanks, Fang Yuan, Baomin Wang, Mary Pahuski, Julia Wulfkuhle, Isela Gallagher, Alexander F. Koeppel, Sarah Hatef, Christopher Papanicolas, Jeongwu Lee, Eli E. Bar, David Schiff, Stephen D. Turner, Emanuel F. Petricoin, Lloyd S. Gray, Roger Abounader
Journal: Cancer Research
Cancer Res (2017) 77 (13): 3479–3490.
https://doi.org/10.1158/0008-5472.CAN-16-2347
Published: 02 July 2017
View articletitled, Targetable T-type Calcium Channels Drive Glioblastoma
Open the PDF for Targetable T-type Calcium Channels Drive Glioblastoma in another window
Includes: Supplementary data
Journal Articles

Abstract 102: Overcoming MET inhibitor resistance in GBM therapy

Free
Nichola A. Cruickshanks, Ying Zhang, Sarah Hatef, Julia Wulfkuhle, Isela Gallagher, Alexander Koeppel, David Schiff, See Phan, Stephen Turner, Emanuel Petricoin, Roger Abounader
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 102.
https://doi.org/10.1158/1538-7445.AM2017-102
Published: 01 July 2017
View articletitled, Abstract 102: Overcoming MET inhibitor resistance in GBM therapy
Journal Articles

Abstract 345: PTEN tumor suppressive effects in glioblastoma are partly mediated by MET downregulation via a p53-miR-34a axis

Free
Fadilla Guessous, Nichola A. Cruickshanks, Ying Zhang, David Schiff, Jann Sarkaria, Roger Abounader
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 345.
https://doi.org/10.1158/1538-7445.AM2017-345
Published: 01 July 2017
View articletitled, Abstract 345: PTEN tumor suppressive effects in glioblastoma are partly mediated by MET downregulation via a p53-miR-34a axis
Journal Articles

Abstract 3147: Comprehensive characterization of the role of T-type calcium channels in glioblastoma

Free
Ying Zhang, Nichola Cruickshanks, Fang Yuan, Baomin Wang, Mary Pahuski, Julia Wulfkuhle, Isela Gallagher, Alexander F. Koeppel, Sarah Hatef, Christopher Papanicolas, Jeongwu Lee, Eli Bar, David Schiff, Stephen D. Turner, Emanuel Petricoin, Lloyd L. Gray, Roger Abouander
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3147.
https://doi.org/10.1158/1538-7445.AM2017-3147
Published: 01 July 2017
View articletitled, Abstract 3147: Comprehensive characterization of the role of T-type calcium channels in glioblastoma
Journal Articles

Abstract 5222: microRNA-148a is a prognostic oncomiR that targets MIG6 and BIM to regulate EGFR and apoptosis in glioblastoma

Free
Jungeun Kim, Ying Zhang, Michael Skalski, Josie Hayes, Benjamin Kefas, David Schiff, Benjamin Purow, Sarah Parsons, Sean Lawler, Roger Abounader
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5222.
https://doi.org/10.1158/1538-7445.AM2014-5222
Published: 01 October 2014
View articletitled, Abstract 5222: microRNA-148a is a prognostic oncomiR that targets MIG6 and BIM to regulate EGFR and apoptosis in glioblastoma
Journal Articles

Abstract 1909: Identification and characterization of microRNA-134 as a novel receptor tyrosine kinase-regulated tumor suppressive hub in glioblastoma

Free
Ying Zhang, Jungeun Kim, Adam C. Mueller, Bijan Dey, Yanzhi Yang, Daehee Lee, Jan Hachmann, Sanjo Finderle, Deric M. Park, James Christensen, David Schiff, Benjamin Purow, Anindya Dutta, Roger Abounader
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1909.
https://doi.org/10.1158/1538-7445.AM2014-1909
Published: 01 October 2014
View articletitled, Abstract 1909: Identification and characterization of microRNA-134 as a novel receptor tyrosine kinase-regulated tumor suppressive hub in glioblastoma
Journal Articles

microRNA-148a Is a Prognostic oncomiR That Targets MIG6 and BIM to Regulate EGFR and Apoptosis in Glioblastoma

Free
Jungeun Kim, Ying Zhang, Michael Skalski, Josie Hayes, Benjamin Kefas, David Schiff, Benjamin Purow, Sarah Parsons, Sean Lawler, Roger Abounader
Journal: Cancer Research
Cancer Res (2014) 74 (5): 1541–1553.
https://doi.org/10.1158/0008-5472.CAN-13-1449
Published: 02 March 2014
View articletitled, microRNA-148a Is a Prognostic oncomiR That Targets MIG6 and BIM to Regulate EGFR and Apoptosis in Glioblastoma
Open the PDF for microRNA-148a Is a Prognostic oncomiR That Targets MIG6 and BIM to Regulate EGFR and Apoptosis in Glioblastoma in another window
Includes: Supplementary data
Journal Articles

Abstract 5081: Comprehensive genomic analysis of primary CNS lymphomas (PCNSL) identifies multiple dysregulated genes involved in immune response, regulation of apoptosis, lymphocyte maturation and activation

Free
Esteban Braggio, Brian P. O'Neill, Ryan Robetorye, William Macon, David Schiff, Maria B. Lopes, Ellen McPhail, Rafael Fonseca
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5081.
https://doi.org/10.1158/1538-7445.AM2012-5081
Published: 15 April 2012
View articletitled, Abstract 5081: Comprehensive genomic analysis of primary CNS lymphomas (PCNSL) identifies multiple dysregulated genes involved in immune response, regulation of apoptosis, lymphocyte maturation and activation
Journal Articles

Abstract 1821: Hepatocyte growth factor sensitizes brain tumor cells and xenografts to c-Met kinase inhibition

Free
Ying Zhang, Kaithlyn Farenholtz, Yanzhi Yang, Fadila Guessous, David Schiff, Benjamin Purow, James Christensen, Roger Abounader
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1821.
https://doi.org/10.1158/1538-7445.AM2012-1821
Published: 15 April 2012
View articletitled, Abstract 1821: Hepatocyte growth factor sensitizes brain tumor cells and xenografts to c-Met kinase inhibition
Journal Articles

Abstract 1252: Cooperation between c-Met and focal adhesion kinase pathways in medulloblastoma and implications for therapy

Free
Fadila Guessous, Yanzhi Yang, Elizabeth Johnson, Lukasz Marcinkiewicz, Matthew Smith, Ying Zhang, Alexander Kofman, David Schiff, James Christensen, Roger Abounader
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1252.
https://doi.org/10.1158/1538-7445.AM2012-1252
Published: 15 April 2012
View articletitled, Abstract 1252: Cooperation between c-Met and focal adhesion kinase pathways in medulloblastoma and implications for therapy
Journal Articles

Abstract 126: Characterization of microRNA-10b in human glioblastoma

Free
Fadila Guessous, Melissa Alvarado, Ying Zhang, Simon Heister, Benjamin Kefas, David Schiff, Roger Abounader
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 126.
https://doi.org/10.1158/1538-7445.AM2011-126
Published: 15 April 2011
View articletitled, Abstract 126: Characterization of microRNA-10b in human glioblastoma
Journal Articles

Abstract 2067: Effects of microRNA-34a on brain tumor cells and glioblastoma stem cells

Free
Fadila Guessous, Ying Zhang, Alessia Catania, Yunqing Li, Alexander Kofman, Benjamin Kefas, David Schiff, Benjamin Purow, Roger Abounader
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2067.
https://doi.org/10.1158/1538-7445.AM10-2067
Published: 15 April 2010
View articletitled, Abstract 2067: Effects of microRNA-34a on brain tumor cells and glioblastoma stem cells
Journal Articles

Abstract 331: A comprehensive high-resolution genomic analysis of primary central nervous system lymphomas (PCNSL) shows a highly complex karyotype characterized by abnormalities affecting multiple genes involved in critical pathways associated with lymphocyte maturation and survival

Free
Brian Patrick O'Neill, Esteban Braggio, M. Beatriz Lopez, David Schiff, William R. Macon, Caterina Giannini, Rafael Fonseca
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 331.
https://doi.org/10.1158/1538-7445.AM10-331
Published: 15 April 2010
View articletitled, Abstract 331: A comprehensive high-resolution genomic analysis of primary central nervous system lymphomas (PCNSL) shows a highly complex karyotype characterized by abnormalities affecting multiple genes involved in critical pathways associated with lymphocyte maturation and survival
Journal Articles

MicroRNA-34a Inhibits Glioblastoma Growth by Targeting Multiple Oncogenes

Free
Yunqing Li, Fadila Guessous, Ying Zhang, Charles DiPierro, Benjamin Kefas, Elizabeth Johnson, Lukasz Marcinkiewicz, Jinmai Jiang, Yanzhi Yang, Thomas D. Schmittgen, Beatriz Lopes, David Schiff, Benjamin Purow, Roger Abounader
Journal: Cancer Research
Cancer Res (2009) 69 (19): 7569–7576.
https://doi.org/10.1158/0008-5472.CAN-09-0529
Published: 01 October 2009
View articletitled, MicroRNA-34a Inhibits Glioblastoma Growth by Targeting Multiple Oncogenes
Open the PDF for MicroRNA-34a Inhibits Glioblastoma Growth by Targeting Multiple Oncogenes in another window
Journal Articles

Abstract #1966: microRNA-34a inhibits brain tumor growth by targeting multiple oncogenes

Free
Yunqing Li, Fadila Guessous, Charles Dipierro, Ying Zhang, Benjamin Kefas, Elizabeth Johnson, Jinmai Jiang, Beatriz Lopes, David Schiff, Thomas Schmittgen, Benjamin Purow, Roger Abounader
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1966.
Published: 01 May 2009
View articletitled, Abstract #1966: microRNA-34a inhibits brain tumor growth by targeting multiple oncogenes
Journal Articles

Abstract #5574: SGX523 potently inhibits c-Met activation and c-Met-dependent malignancy and in vivo glioblastoma growth

Free
Fadila Guessous, Ying Zhang, Charles DiPierro, Yunqing Li, Lukasz Marcinkiewicz, David Schiff, Sean Buchanan, Roger Abounader
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 5574.
Published: 01 May 2009
View articletitled, Abstract #5574: SGX523 potently inhibits c-Met activation and c-Met-dependent malignancy and in vivo glioblastoma growth
Journal Articles

Abstract #3781: ANG1005 (Angiopep-2/paclitaxel conjugate) as a promising new drug therapy for patients with malignant glioma

Free
Jean-Paul Castaigne, Tom Mikkelsen, David Schiff, Patrick Wen, Steven Rosenfeld, Morris Groves, Eric Wong, Kelly Elian, Ann Neale, Betty Lawrence, Jan Drappatz
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3781.
Published: 01 May 2009
View articletitled, Abstract #3781: ANG1005 (Angiopep-2/paclitaxel conjugate) as a promising new drug therapy for patients with malignant glioma
Journal Articles

microRNA-34a is a tumor suppressor that inhibits c-Met in human gliomas.

Free
Yunqing Li, Fadila Guessous, Elizabeth Johnson, David Schiff, Benjamin Purow, Roger Abounader
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5022.
Published: 01 May 2008
View articletitled, microRNA-34a is a tumor suppressor that inhibits c-Met in human gliomas.
Journal Articles

PTEN regulates c-Met-dependent malignancy and associated molecular events and influences c-Met-targeted therapies in glioblastoma.

Free
Yunqing Li, Fadila Guessous, Tucker Mudrick, Elizabeth Johnson, Lauren Fuller, Charles DiPierro, David Schiff, Roger Abounader
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 119.
Published: 01 May 2008
View articletitled, PTEN regulates c-Met-dependent malignancy and associated molecular events and influences c-Met-targeted therapies in glioblastoma.
Journal Articles

Racial/ethnic differences in primary central nervous system lymphoma (PCNSL): A National Cancer Institute (NCI) Surveillance, Epidemiology and End Results (SEER) program estimate of incidence and survival rates among United States (US) blacks, whites, Asian/Pacific Islanders (A/PI) and American Indians/Alaskan Natives (AI/AN)

Free
Brian O'Neill, Jose Pulido, Robert Vierkant, Janet Olson, Lauren Abrery, David Schiff
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3842.
Published: 01 May 2008
View articletitled, Racial/ethnic differences in primary central nervous system lymphoma (PCNSL): A National Cancer Institute (NCI) Surveillance, Epidemiology and End Results (SEER) program estimate of incidence and survival rates among United States (US) blacks, whites, Asian/Pacific Islanders (A/PI) and American Indians/Alaskan Natives (AI/AN)