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Journal Articles

Abstract 410: ASXL3 is a potential biomarker of response of SCLC to targeted therapies

Ruihong Wang, Haitao Wang, Xinwei Wu, Keerti Mishra, Stephanie Shiffka, Frank Hernandez, Mary Zhang, Umay Tuana Tolunay, Sudheer Gara, Sichuan Xi, Shamus R. Carr, Choung D. Hoang, David S. Schrump

Cancer Res (2024) 84 (6_Supplement): 410.

https://doi.org/10.1158/1538-7445.AM2024-410

Published: 22 March 2024

View article titled, Abstract 410: ASXL3 is a potential biomarker of response of SCLC to targeted therapies

Journal Articles

Abstract 5445: Unravelling the molecular mechanisms of stemness in small cell lung cancer using an iPSC-based approach

Sudheer Kumar Gara, Haitao Wang, Anand Singh, Tuana Tolunay, Vivek Shukla, Ruihong Wang, Mary Zhang, Stephanie Shiffka, David S. Schrump

Cancer Res (2024) 84 (6_Supplement): 5445.

https://doi.org/10.1158/1538-7445.AM2024-5445

Published: 22 March 2024

View article titled, Abstract 5445: Unravelling the molecular mechanisms of stemness in small cell lung cancer using an iPSC-based approach

Journal Articles

Abstract 7545: Epigenetic plasticity in rewiring DNMT1/UHRF1-RB1- NFkB signaling circuit regulates asbestos-induced mesothelial malignant transformation

Sichuan Xi, Xinwei Wu, David M Straughan, Eden C Payabyab, Haitao Wang, Ruihong Wang, Mary Zhang, Shamus R. Carr, Chuong D. Hoang, David S. Schrump

Cancer Res (2024) 84 (6_Supplement): 7545.

https://doi.org/10.1158/1538-7445.AM2024-7545

Published: 22 March 2024

View article titled, Abstract 7545: Epigenetic plasticity in rewiring DNMT1/UHRF1-RB1- NFkB signaling circuit regulates asbestos-induced mesothelial malignant transformation

Journal Articles

Abstract 7544: Bromodomain and extra-terminal protein inhibitors deplete nuclear factor 1C and reduce stemness and growth of human small cell lung cancer cells in vitro and in vivo

Haitao Wang, Ruihong Wang, Frank Villa-Hernandez, Vivek Shukla, Lyuba Varticovski, Songjoon Baek, Frank Echtenkamp, Sudheer Kumar Gara, Mary R. Zhang, Stephanie Shiffka, Razi Raziuddin, Leonard M. Neckers, W. Marston Linehan, Gordon L. Hager, Shamus R. Carr, Chuong D. Hoang, Haobin Chen, David S. Schrump

Cancer Res (2024) 84 (6_Supplement): 7544.

https://doi.org/10.1158/1538-7445.AM2024-7544

Published: 22 March 2024

View article titled, Abstract 7544: Bromodomain and extra-terminal protein inhibitors deplete nuclear factor 1C and reduce stemness and growth of human small cell lung cancer cells in vitro and in vivo

Journal Articles

Abstract A013: Induced pluripotent stem cells derived from normal human esophageal epithelial cells identify transcription factor networks contributing to esophageal carcinogenesis

Haitao Wang, Ruihong Wang, Katherine P. Prothro, Sichuan Xi, Weilong Hou, Xinwei Wu, Tuana Tolunay, Vivek Shukla, Mary R. Zhang, Stephanie J. Shiffka, Sudheer Gara, David S. Schrump

Cancer Res (2022) 82 (23_Supplement_2): A013.

https://doi.org/10.1158/1538-7445.CancEpi22-A013

Published: 01 December 2022

View article titled, Abstract A013: Induced pluripotent stem cells derived from normal human esophageal epithelial cells identify transcription factor networks contributing to esophageal carcinogenesis

Journal Articles

Abstract 5470: Inhibition of facilitates chromatin transcription complex attenuates mesothelioma growth

Anand Singh, Nathanael Pruett, Roma Pahwa, Sudheer K. Gara, Shivani Dixit, Agnes Choi, David S. Schrump, Chuong D. Hoang

Cancer Res (2022) 82 (12_Supplement): 5470.

https://doi.org/10.1158/1538-7445.AM2022-5470

Published: 15 June 2022

View article titled, Abstract 5470: Inhibition of facilitates chromatin transcription complex attenuates mesothelioma growth

Journal Articles

Abstract 5328: mTOR inhibitor enhances anti-tumor effect of BET bromodomain inhibitor in small cell lung cancer

ANJU KUMARI, Lisa Gesumaria, Patricia Fetsch, Markku Miettinen, Keith Hughitt, Beverly Mock, Craig Thomas, David S. Schrump, Haobin Chen

Cancer Res (2020) 80 (16_Supplement): 5328.

https://doi.org/10.1158/1538-7445.AM2020-5328

Published: 15 August 2020

View article titled, Abstract 5328: mTOR inhibitor enhances anti-tumor effect of BET bromodomain inhibitor in small cell lung cancer

Journal Articles

Abstract 2943: Severe hepatotoxicity of mithramycin therapy caused by altering expression of hepatocellular bile transporters

Tristan M. Sissung, Phoebe A. Huang, Ralph Hauke, Edel McCrea, Cody J. Peer, Roberto H. Barbier, Jonathan D. Strope, Ariel M. Ley, Mary Zhang, Julie A. Hong, David Venzon, Jonathan P. Jackson, Kenneth R. Brouwer, Patrick Grohar, John Glod, Brigitte C. Widemann, Theo Heller, David S. Schrump, William D. Figg

Cancer Res (2019) 79 (13_Supplement): 2943.

https://doi.org/10.1158/1538-7445.AM2019-2943

Published: 01 July 2019

View article titled, Abstract 2943: Severe hepatotoxicity of mithramycin therapy caused by altering expression of hepatocellular bile transporters

Journal Articles

Abstract 523: miR-206 inhibits pleural mesothelioma by targeting an active KRAS/CDK4/CCND1 pathway

Anand Singh, Roma Pahwa, Li Zhang, Nathanael Pruett, R Taylor Ripley, David S. Schrump, Chuong D. Hoang

Cancer Res (2018) 78 (13_Supplement): 523.

https://doi.org/10.1158/1538-7445.AM2018-523

Published: 01 July 2018

View article titled, Abstract 523: miR-206 inhibits pleural mesothelioma by targeting an active KRAS/CDK4/CCND1 pathway

Journal Articles

ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer

Cancer Res (2017) 77 (22): 6267–6281.

https://doi.org/10.1158/0008-5472.CAN-17-0570

Published: 14 November 2017

View article titled, ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer

Includes: Supplementary data

Journal Articles

Abstract 1005: Mitochondrial inhibition decreases the malignant phenotype of esophageal adenocarcinoma cells through the induction of autophagy

Deborah R. Depew, Paul L. Feingold, Kate Brown, Yuan Xu, Mahadev Rao, Michael Moses, Leonard M. Neckers, David S. Schrump, R Taylor Ripley.

Cancer Res (2016) 76 (14_Supplement): 1005.

https://doi.org/10.1158/1538-7445.AM2016-1005

Published: 15 July 2016

View article titled, Abstract 1005: Mitochondrial inhibition decreases the malignant phenotype of esophageal adenocarcinoma cells through the induction of autophagy

Journal Articles

Abstract 1033: Cigarette smoke and bile acids induce metabolic reprogramming mediated by uncoupling protein-2 (UCP2) during esophageal carcinogenesis

Yuan Xu, Kate Brown, Deborah R. Depew, Paul L. Feingold, Mahadev Rao, Jeremy Davis, David S. Schrump, R. Taylor Ripley.

Cancer Res (2016) 76 (14_Supplement): 1033.

https://doi.org/10.1158/1538-7445.AM2016-1033

Published: 15 July 2016

View article titled, Abstract 1033: Cigarette smoke and bile acids induce metabolic reprogramming mediated by uncoupling protein-2 (UCP2) during esophageal carcinogenesis

Journal Articles

Abstract 675: Jarid2 is a novel target for lung cancer therapy.

Young K. Hong, Mary Zhang, Scott Atay, Manish Raiji, Trevor Upham, Julie A. Hong, Mahadev Rao, David S. Schrump

Cancer Res (2013) 73 (8_Supplement): 675.

https://doi.org/10.1158/1538-7445.AM2013-675

Published: 15 April 2013

View article titled, Abstract 675: Jarid2 is a novel target for lung cancer therapy.

Journal Articles

Abstract 3071: Epigenetic repression of miR-217 contributes to tobacco-induced esophageal carcinogenesis.

Sichuan Xi, Suzanne Inchauste, Zuoxiang Xiao, Jigui Shan, Mary Zhang, Julie A. Hong, Manish T Raiji, David G. Beer, David S. Schrump

Cancer Res (2013) 73 (8_Supplement): 3071.

https://doi.org/10.1158/1538-7445.AM2013-3071

Published: 15 April 2013

View article titled, Abstract 3071: Epigenetic repression of miR-217 contributes to tobacco-induced esophageal carcinogenesis.

Journal Articles

Aryl Hydrocarbon Receptor-Induced Adrenomedullin Mediates Cigarette Smoke Carcinogenicity in Humans and Mice

Sergio Portal-Nuñez, Uma T. Shankavaram, Mahadev Rao, Nicole Datrice, Scott Atay, Marta Aparicio, Kevin A. Camphausen, Pedro M. Fernández-Salguero, Han Chang, Pinpin Lin, David S. Schrump, Stavros Garantziotis, Frank Cuttitta, Enrique Zudaire

Cancer Res (2012) 72 (22): 5790–5800.

https://doi.org/10.1158/0008-5472.CAN-12-0818

Published: 14 November 2012

View article titled, Aryl Hydrocarbon Receptor-Induced Adrenomedullin Mediates Cigarette Smoke Carcinogenicity in Humans and Mice

Includes: Supplementary data

Journal Articles

Mithramycin Represses Basal and Cigarette Smoke–Induced Expression of ABCG2 and Inhibits Stem Cell Signaling in Lung and Esophageal Cancer Cells

Cancer Res (2012) 72 (16): 4178–4192.

https://doi.org/10.1158/0008-5472.CAN-11-3983

Published: 14 August 2012

View article titled, Mithramycin Represses Basal and Cigarette Smoke–Induced Expression of ABCG2 and Inhibits Stem Cell Signaling in Lung and Esophageal Cancer Cells

Includes: Supplementary data

Journal Articles

Abstract 2560: IKKα inactivation predisposes to spontaneous lung squamous cell carcinomas

Zuoxiang Xiao, Qun Jiang, Jami Willette-Brown, Feng Zhu, Howard A. Young, Fanching Lin, Sandra Burkett, Mahesh Datla, Sichuan Xi, David S. Schrump, Robert H. Wiltrout, Yinling Hu

Cancer Res (2012) 72 (8_Supplement): 2560.

https://doi.org/10.1158/1538-7445.AM2012-2560

Published: 15 April 2012

View article titled, Abstract 2560: IKKα inactivation predisposes to spontaneous lung squamous cell carcinomas

Journal Articles

Inhibition of Histone Lysine Methylation Enhances Cancer–Testis Antigen Expression in Lung Cancer Cells: Implications for Adoptive Immunotherapy of Cancer

Mahadev Rao, Nachimuthu Chinnasamy, Julie A. Hong, Yuwei Zhang, Mary Zhang, Sichuan Xi, Fang Liu, Victor E. Marquez, Richard A. Morgan, David S. Schrump

Cancer Res (2011) 71 (12): 4192–4204.

https://doi.org/10.1158/0008-5472.CAN-10-2442

Published: 14 June 2011

View article titled, Inhibition of Histone Lysine Methylation Enhances Cancer–Testis Antigen Expression in Lung Cancer Cells: Implications for Adoptive Immunotherapy of Cancer

Includes: Supplementary data

Journal Articles

Abstract 2057: Cigarette smoke enhances pulmonary carcinogenesis via downregulation of has-miR-487b in respiratory epithelial cells

Sichuan Xi, Maocheng Yang, Yong-Guang Tao, Jiqui Shan, Hong Xu, Mary Zhang, David S. Schrump

Cancer Res (2010) 70 (8_Supplement): 2057.

https://doi.org/10.1158/1538-7445.AM10-2057

Published: 15 April 2010

View article titled, Abstract 2057: Cigarette smoke enhances pulmonary carcinogenesis via downregulation of has-miR-487b in respiratory epithelial cells

Journal Articles

Abstract 2013: Integrative genomic studies pertaining to cigarette smoke and human lung carcinogenesis

Maocheng Yang, Sichuan Xi, Fang Liu, Mahadev Rao, David S. Schrump

Cancer Res (2010) 70 (8_Supplement): 2013.

https://doi.org/10.1158/1538-7445.AM10-2013

Published: 15 April 2010

View article titled, Abstract 2013: Integrative genomic studies pertaining to cigarette smoke and human lung carcinogenesis

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Abstract 410: ASXL3 is a potential biomarker of response of SCLC to targeted therapies

Abstract 5445: Unravelling the molecular mechanisms of stemness in small cell lung cancer using an iPSC-based approach

Abstract 7545: Epigenetic plasticity in rewiring DNMT1/UHRF1-RB1- NFkB signaling circuit regulates asbestos-induced mesothelial malignant transformation

Abstract 7544: Bromodomain and extra-terminal protein inhibitors deplete nuclear factor 1C and reduce stemness and growth of human small cell lung cancer cells in vitro and in vivo

Abstract A013: Induced pluripotent stem cells derived from normal human esophageal epithelial cells identify transcription factor networks contributing to esophageal carcinogenesis

Abstract 5470: Inhibition of facilitates chromatin transcription complex attenuates mesothelioma growth

Abstract 5328: mTOR inhibitor enhances anti-tumor effect of BET bromodomain inhibitor in small cell lung cancer

Abstract 2943: Severe hepatotoxicity of mithramycin therapy caused by altering expression of hepatocellular bile transporters

Abstract 523: miR-206 inhibits pleural mesothelioma by targeting an active KRAS/CDK4/CCND1 pathway

ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer

Abstract 1005: Mitochondrial inhibition decreases the malignant phenotype of esophageal adenocarcinoma cells through the induction of autophagy

Abstract 1033: Cigarette smoke and bile acids induce metabolic reprogramming mediated by uncoupling protein-2 (UCP2) during esophageal carcinogenesis

Abstract 675: Jarid2 is a novel target for lung cancer therapy.

Abstract 3071: Epigenetic repression of miR-217 contributes to tobacco-induced esophageal carcinogenesis.

Aryl Hydrocarbon Receptor-Induced Adrenomedullin Mediates Cigarette Smoke Carcinogenicity in Humans and Mice

Mithramycin Represses Basal and Cigarette Smoke–Induced Expression of ABCG2 and Inhibits Stem Cell Signaling in Lung and Esophageal Cancer Cells

Abstract 2560: IKKα inactivation predisposes to spontaneous lung squamous cell carcinomas

Inhibition of Histone Lysine Methylation Enhances Cancer–Testis Antigen Expression in Lung Cancer Cells: Implications for Adoptive Immunotherapy of Cancer

Abstract 2057: Cigarette smoke enhances pulmonary carcinogenesis via downregulation of has-miR-487b in respiratory epithelial cells

Abstract 2013: Integrative genomic studies pertaining to cigarette smoke and human lung carcinogenesis

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