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David S. Schrump
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Journal Articles

Abstract 5470: Inhibition of facilitates chromatin transcription complex attenuates mesothelioma growth

Anand Singh, Nathanael Pruett, Roma Pahwa, Sudheer K. Gara, Shivani Dixit, Agnes Choi, David S. Schrump, Chuong D. Hoang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5470.
DOI: https://doi.org/10.1158/1538-7445.AM2022-5470
Published: 15 June 2022
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Journal Articles

Abstract 5328: mTOR inhibitor enhances anti-tumor effect of BET bromodomain inhibitor in small cell lung cancer

ANJU KUMARI, Lisa Gesumaria, Patricia Fetsch, Markku Miettinen, Keith Hughitt, Beverly Mock, Craig Thomas, David S. Schrump, Haobin Chen
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5328.
DOI: https://doi.org/10.1158/1538-7445.AM2020-5328
Published: 15 August 2020
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Abstract 2943: Severe hepatotoxicity of mithramycin therapy caused by altering expression of hepatocellular bile transporters

Tristan M. Sissung, Phoebe A. Huang, Ralph Hauke, Edel McCrea, Cody J. Peer, Roberto H. Barbier, Jonathan D. Strope, Ariel M. Ley, Mary Zhang, Julie A. Hong, David Venzon, Jonathan P. Jackson, Kenneth R. Brouwer, Patrick Grohar, John Glod, Brigitte C. Widemann, Theo Heller, David S. Schrump, William D. Figg
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2943.
DOI: https://doi.org/10.1158/1538-7445.AM2019-2943
Published: 01 July 2019
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Journal Articles

Abstract 523: miR-206 inhibits pleural mesothelioma by targeting an active KRAS/CDK4/CCND1 pathway

Anand Singh, Roma Pahwa, Li Zhang, Nathanael Pruett, R Taylor Ripley, David S. Schrump, Chuong D. Hoang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 523.
DOI: https://doi.org/10.1158/1538-7445.AM2018-523
Published: 01 July 2018
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Journal Articles

ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer

Vivek Shukla, Mahadev Rao, Hongen Zhang, Jeanette Beers, Darawalee Wangsa, Danny Wangsa, Floryne O. Buishand, Yonghong Wang, Zhiya Yu, Holly S. Stevenson, Emily S. Reardon, Kaitlin C. McLoughlin, Andrew S. Kaufman, Eden C. Payabyab, Julie A. Hong, Mary Zhang, Sean Davis, Daniel Edelman, Guokai Chen, Markku M. Miettinen, Nicholas P. Restifo, Thomas Ried, Paul A. Meltzer, David S. Schrump
Journal: Cancer Research
Cancer Res (2017) 77 (22): 6267–6281.
DOI: https://doi.org/10.1158/0008-5472.CAN-17-0570
Published: 14 November 2017
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Includes: Supplementary data
Journal Articles

Abstract 1005: Mitochondrial inhibition decreases the malignant phenotype of esophageal adenocarcinoma cells through the induction of autophagy

Deborah R. Depew, Paul L. Feingold, Kate Brown, Yuan Xu, Mahadev Rao, Michael Moses, Leonard M. Neckers, David S. Schrump, R Taylor Ripley.
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1005.
DOI: https://doi.org/10.1158/1538-7445.AM2016-1005
Published: 15 July 2016
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Journal Articles

Abstract 1033: Cigarette smoke and bile acids induce metabolic reprogramming mediated by uncoupling protein-2 (UCP2) during esophageal carcinogenesis

Yuan Xu, Kate Brown, Deborah R. Depew, Paul L. Feingold, Mahadev Rao, Jeremy Davis, David S. Schrump, R. Taylor Ripley.
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1033.
DOI: https://doi.org/10.1158/1538-7445.AM2016-1033
Published: 15 July 2016
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Journal Articles

Abstract 675: Jarid2 is a novel target for lung cancer therapy.

Young K. Hong, Mary Zhang, Scott Atay, Manish Raiji, Trevor Upham, Julie A. Hong, Mahadev Rao, David S. Schrump
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 675.
DOI: https://doi.org/10.1158/1538-7445.AM2013-675
Published: 15 April 2013
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Journal Articles

Abstract 3071: Epigenetic repression of miR-217 contributes to tobacco-induced esophageal carcinogenesis.

Sichuan Xi, Suzanne Inchauste, Zuoxiang Xiao, Jigui Shan, Mary Zhang, Julie A. Hong, Manish T Raiji, David G. Beer, David S. Schrump
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3071.
DOI: https://doi.org/10.1158/1538-7445.AM2013-3071
Published: 15 April 2013
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Journal Articles

Aryl Hydrocarbon Receptor-Induced Adrenomedullin Mediates Cigarette Smoke Carcinogenicity in Humans and Mice

Sergio Portal-Nuñez, Uma T. Shankavaram, Mahadev Rao, Nicole Datrice, Scott Atay, Marta Aparicio, Kevin A. Camphausen, Pedro M. Fernández-Salguero, Han Chang, Pinpin Lin, David S. Schrump, Stavros Garantziotis, Frank Cuttitta, Enrique Zudaire
Journal: Cancer Research
Cancer Res (2012) 72 (22): 5790–5800.
DOI: https://doi.org/10.1158/0008-5472.CAN-12-0818
Published: 14 November 2012
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Includes: Supplementary data
Journal Articles

Mithramycin Represses Basal and Cigarette Smoke–Induced Expression of ABCG2 and Inhibits Stem Cell Signaling in Lung and Esophageal Cancer Cells

Mary Zhang, Aarti Mathur, Yuwei Zhang, Sichuan Xi, Scott Atay, Julie A. Hong, Nicole Datrice, Trevor Upham, Clinton D. Kemp, R. Taylor Ripley, Gordon Wiegand, Itzak Avital, Patricia Fetsch, Haresh Mani, Daniel Zlott, Robert Robey, Susan E. Bates, Xinmin Li, Mahadev Rao, David S. Schrump
Journal: Cancer Research
Cancer Res (2012) 72 (16): 4178–4192.
DOI: https://doi.org/10.1158/0008-5472.CAN-11-3983
Published: 14 August 2012
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Includes: Supplementary data
Journal Articles

Abstract 2560: IKKα inactivation predisposes to spontaneous lung squamous cell carcinomas

Zuoxiang Xiao, Qun Jiang, Jami Willette-Brown, Feng Zhu, Howard A. Young, Fanching Lin, Sandra Burkett, Mahesh Datla, Sichuan Xi, David S. Schrump, Robert H. Wiltrout, Yinling Hu
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2560.
DOI: https://doi.org/10.1158/1538-7445.AM2012-2560
Published: 15 April 2012
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Journal Articles

Inhibition of Histone Lysine Methylation Enhances Cancer–Testis Antigen Expression in Lung Cancer Cells: Implications for Adoptive Immunotherapy of Cancer

Mahadev Rao, Nachimuthu Chinnasamy, Julie A. Hong, Yuwei Zhang, Mary Zhang, Sichuan Xi, Fang Liu, Victor E. Marquez, Richard A. Morgan, David S. Schrump
Journal: Cancer Research
Cancer Res (2011) 71 (12): 4192–4204.
DOI: https://doi.org/10.1158/0008-5472.CAN-10-2442
Published: 14 June 2011
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Includes: Supplementary data
Journal Articles

Abstract 4876: DZNep enhances apoptosis and augments cancer-testis antigen expression mediated by DNA demethylating agents and histone deacetylase inhibitors in lung cancer cells

Mahadev Rao, Nachimuthu Chinnasamy, Julie A. Hong, Yuwei Zhang, Richard A. Morgan, Victor E. Marquez, David S. Schrump
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4876.
DOI: https://doi.org/10.1158/1538-7445.AM10-4876
Published: 15 April 2010
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Journal Articles

Abstract 4250: Cigarette smoke induces expression of the putative stem cell marker ABCG2 in cultured esophageal adenocarcinoma cells

Aarti Mathur, Mahadev Rao, Yuwei Zhang, Mary Zhang, Clint D. Kemp, Robert T. Ripley, Julie Hong, Fang Liu, Itzhak Avital, David S. Schrump
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4250.
DOI: https://doi.org/10.1158/1538-7445.AM10-4250
Published: 15 April 2010
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Journal Articles

Abstract 3415: Therapeutic targeting of the ASPL-TFE3 gene fusion in ASPS-1, a novel cell line derived from metastatic alveolar soft part sarcoma (ASPS)

David T. Vistica, Susan Kenney, Sandra Burkett, Melinda Hollingshead, Suzanne Borgel, Donna Butcher, David S. Schrump, Robert H. Shoemaker
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3415.
DOI: https://doi.org/10.1158/1538-7445.AM10-3415
Published: 15 April 2010
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Journal Articles

Abstract 2057: Cigarette smoke enhances pulmonary carcinogenesis via downregulation of has-miR-487b in respiratory epithelial cells

Sichuan Xi, Maocheng Yang, Yong-Guang Tao, Jiqui Shan, Hong Xu, Mary Zhang, David S. Schrump
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2057.
DOI: https://doi.org/10.1158/1538-7445.AM10-2057
Published: 15 April 2010
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Journal Articles

Abstract 2013: Integrative genomic studies pertaining to cigarette smoke and human lung carcinogenesis

Maocheng Yang, Sichuan Xi, Fang Liu, Mahadev Rao, David S. Schrump
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2013.
DOI: https://doi.org/10.1158/1538-7445.AM10-2013
Published: 15 April 2010
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Journal Articles

Abstract 5156: Wnt5A enhances the malignant phenotype of lung cancer cells via non-canonical signaling

Robert T. Ripley, Mahadev Rao, Clinton D. Kemp, Aarti Mathur, Mustafa Hussain, Julie A. Hong, Mary Zhang, David S. Schrump
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5156.
DOI: https://doi.org/10.1158/1538-7445.AM10-5156
Published: 15 April 2010
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Journal Articles

Tobacco Smoke Induces Polycomb-Mediated Repression of Dickkopf-1 in Lung Cancer Cells

Mustafa Hussain, Mahadev Rao, Ashley E. Humphries, Julie A. Hong, Fang Liu, Maocheng Yang, Diana Caragacianu, David S. Schrump
Journal: Cancer Research
Cancer Res (2009) 69 (8): 3570–3578.
DOI: https://doi.org/10.1158/0008-5472.CAN-08-2807
Published: 15 April 2009
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Includes: Supplementary data