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Journal Articles

Abstract 6161: PARP inhibition enhances radiotherapy of SMAD4 deficient human head and neck squamous cell carcinomas in experimental models

Christian D. Young, Ariel L. Hernandez, Li Bian, Sana D. Karam, David Raben, Xiao-Jing Wang

Cancer Res (2020) 80 (16_Supplement): 6161.

https://doi.org/10.1158/1538-7445.AM2020-6161

Published: 15 August 2020

View article titled, Abstract 6161: PARP inhibition enhances radiotherapy of SMAD4 deficient human head and neck squamous cell carcinomas in experimental models

Journal Articles

Inhibiting Translation Elongation with SVC112 Suppresses Cancer Stem Cells and Inhibits Growth in Head and Neck Squamous Carcinoma

Stephen B. Keysar, Nathan Gomes, Bettina Miller, Brian C. Jackson, Phuong N. Le, J. Jason Morton, Julie Reisinger, Tugs-Saikhan Chimed, Karina E. Gomez, Cera Nieto, Barbara Frederick, Gijsbertus J. Pronk, Hilary L. Somerset, Aik-Choon Tan, Xiao-Jing Wang, David Raben, Tin Tin Su, Antonio Jimeno

Cancer Res (2020) 80 (5): 1183–1198.

https://doi.org/10.1158/0008-5472.CAN-19-3232

Published: 02 March 2020

View article titled, Inhibiting Translation Elongation with SVC112 Suppresses Cancer Stem Cells and Inhibits Growth in Head and Neck Squamous Carcinoma

Includes: Supplementary data

Journal Articles

Abstract 5035: Blockade of EphB4-ephrin-B2 interaction remodels the tumor immune microenvironment in head and neck cancers

Shilpa Bhatia, Ayman Oweida, Shelby Lennon, Laurel Darragh, Sanjana Bukkapatnam, Benjamin Van Court, David Raben, Natalie Serkova, Antonio Jimeno, Eric Clambey, Elena Pasquale, Sana Karam

Cancer Res (2019) 79 (13_Supplement): 5035.

https://doi.org/10.1158/1538-7445.AM2019-5035

Published: 01 July 2019

View article titled, Abstract 5035: Blockade of EphB4-ephrin-B2 interaction remodels the tumor immune microenvironment in head and neck cancers

Journal Articles

Abstract CT123: IMvoke010: Randomized Phase III study of atezolizumab as adjuvant monotherapy after definitive therapy of squamous cell carcinoma of the head and neck (SCCHN)

Deborah J. Wong, Jerome Fayette, Ye Guo, Matthew Kowgier, Ezra Cohen, Ricard Mesia Nin, Arunee Dechaphunkul, Kumar Prabhash, Jessica Geiger, Sarwan Bishnoi, Henning Schafer, Christina Matheny, Fairooz Kabbinavar, Alan Sandler, David Raben, Robert Haddad

Cancer Res (2019) 79 (13_Supplement): CT123.

https://doi.org/10.1158/1538-7445.AM2019-CT123

Published: 01 July 2019

View article titled, Abstract CT123: IMvoke010: Randomized Phase III study of atezolizumab as adjuvant monotherapy after definitive therapy of squamous cell carcinoma of the head and neck (SCCHN)

Journal Articles

Inhibition of EphB4–Ephrin-B2 Signaling Reprograms the Tumor Immune Microenvironment in Head and Neck Cancers

Shilpa Bhatia, Ayman Oweida, Shelby Lennon, Laurel B. Darragh, Dallin Milner, Andy V. Phan, Adam C. Mueller, Benjamin Van Court, David Raben, Natalie J. Serkova, Xiao-Jing Wang, Antonio Jimeno, Eric T. Clambey, Elena B. Pasquale, Sana D. Karam

Cancer Res (2019) 79 (10): 2722–2735.

https://doi.org/10.1158/0008-5472.CAN-18-3257

Published: 15 May 2019

View article titled, Inhibition of EphB4–Ephrin-B2 Signaling Reprograms the Tumor Immune Microenvironment in Head and Neck Cancers

Includes: Supplementary data

Journal Articles

Abstract 5209: Overexpression of TGF-β in Smad4 deficient head and neck squamous cell carcinomas promotes myeloid cell infiltration associated with metastatic progression

Jingjing Yu, Ariel Hernandez, David Raben, Xiao-Jing Wang

Cancer Res (2018) 78 (13_Supplement): 5209.

https://doi.org/10.1158/1538-7445.AM2018-5209

Published: 01 July 2018

View article titled, Abstract 5209: Overexpression of TGF-β in Smad4 deficient head and neck squamous cell carcinomas promotes myeloid cell infiltration associated with metastatic progression

Journal Articles

Abstract 2946: Role of EphB3 receptor in mediating head and neck tumor growth, cell migration, and response to PI3K inhibitor

Shilpa Bhatia, Anastacia Griego, Shelby Lennon, Ayman Oweida, Jaspreet Sharma, Christina Rohmer, Nomin Uyanga, Sanjana Bukkapatnam, Benjamin Van Court, David Raben, Christian Young, Lynn Heasley, Sana D. Karam

Cancer Res (2018) 78 (13_Supplement): 2946.

https://doi.org/10.1158/1538-7445.AM2018-2946

Published: 01 July 2018

View article titled, Abstract 2946: Role of EphB3 receptor in mediating head and neck tumor growth, cell migration, and response to PI3K inhibitor

Journal Articles

Abstract 4169: Inhibition of EphB4-ephrin-B2 signaling results in enhanced sensitivity to cetuximab-radiation therapy in head and neck cancers

Shilpa Bhatia, Jaspreet Sharma, Sanjana Bukkapatnam, Ayman Oweida, Shelby Lennon, Parkash Gill, Antonio Jimeno, David Raben, Lynn Heasley, Sana D. Karam

Cancer Res (2018) 78 (13_Supplement): 4169.

https://doi.org/10.1158/1538-7445.AM2018-4169

Published: 01 July 2018

View article titled, Abstract 4169: Inhibition of EphB4-ephrin-B2 signaling results in enhanced sensitivity to cetuximab-radiation therapy in head and neck cancers

Journal Articles

Abstract 4173: Inhibition of EphB4-ephrinB2 signaling increases efficacy of radiation in pancreatic ductal adenocarcinoma

Shelby Lennon, Shilpa Bhatia, Ayman Oweida, Jaspreet Sharma, Andy Phan, Sanjana Bukkapatnam, Nomin Uyanga, Todd Pitts, Stephen Leong, Karyn Goodman, David Raben, Elena Pasquale, Jorge Martinez-Torrecuadrada, Sana Karam

Cancer Res (2018) 78 (13_Supplement): 4173.

https://doi.org/10.1158/1538-7445.AM2018-4173

Published: 01 July 2018

View article titled, Abstract 4173: Inhibition of EphB4-ephrinB2 signaling increases efficacy of radiation in pancreatic ductal adenocarcinoma

Journal Articles

Abstract 4168: Radioresistant anaplastic thyroid cancers display a unique gene signature and respond to hypofractionated radiotherapy

Ayman J. Oweida, Andy Phan, Benjamin Vancourt, Tyler Robin, David Raben, Bryan Haugen, Nikita Pozdeyev, Rebecca Schweppe, Sana D. Karam

Cancer Res (2018) 78 (13_Supplement): 4168.

https://doi.org/10.1158/1538-7445.AM2018-4168

Published: 01 July 2018

View article titled, Abstract 4168: Radioresistant anaplastic thyroid cancers display a unique gene signature and respond to hypofractionated radiotherapy

Journal Articles

Abstract 2766: Resistance to radiotherapy and PD-L1 blockade is mediated by TIM-3 upregulation in anti-PD-L1 refractory head and neck cancer

Ayman J. Oweida, Mohammad Hararah, Andy Phan, Shilpa Bhatia, Shelby Lennon, David Binder, David Raben, Lynn Heasley, Eric Clambey, Raphael Nemenoff, Sana D. Karam

Cancer Res (2018) 78 (13_Supplement): 2766.

https://doi.org/10.1158/1538-7445.AM2018-2766

Published: 01 July 2018

View article titled, Abstract 2766: Resistance to radiotherapy and PD-L1 blockade is mediated by TIM-3 upregulation in anti-PD-L1 refractory head and neck cancer

Journal Articles

Workshop Report for Cancer Research: Defining the Shades of Gy: Utilizing the Biological Consequences of Radiotherapy in the Development of New Treatment Approaches—Meeting Viewpoint

Cancer Res (2018) 78 (9): 2166–2170.

https://doi.org/10.1158/0008-5472.CAN-17-3760

Published: 30 April 2018

View article titled, Workshop Report for Cancer Research: Defining the Shades of Gy: Utilizing the Biological Consequences of Radiotherapy in the Development of New Treatment Approaches—Meeting Viewpoint

Journal Articles

Hedgehog Signaling Drives Radioresistance and Stroma-Driven Tumor Repopulation in Head and Neck Squamous Cancers

Gregory N. Gan, Justin Eagles, Stephen B. Keysar, Guoliang Wang, Magdalena J. Glogowska, Cem Altunbas, Ryan T. Anderson, Phuong N. Le, J. Jason Morton, Barbara Frederick, David Raben, Xiao-Jing Wang, Antonio Jimeno

Cancer Res (2014) 74 (23): 7024–7036.

https://doi.org/10.1158/0008-5472.CAN-14-1346

Published: 30 November 2014

View article titled, Hedgehog Signaling Drives Radioresistance and Stroma-Driven Tumor Repopulation in Head and Neck Squamous Cancers

Includes: Supplementary data

Journal Articles

Abstract #5232: Autocrine signaling by FGFs and FGFRs in HNSCC cells

Marianne Marshall, Scott Kono, Brady Bichon, Linsday Marek, Barbara Frederick, David Raben, Lynn Heasley

Cancer Res (2009) 69 (9_Supplement): 5232.

Published: 01 May 2009

View article titled, Abstract #5232: Autocrine signaling by FGFs and FGFRs in HNSCC cells

Journal Articles

Abstract #4702: Pathway-based comparison approach for the identification of responders to the mitotic modulator ON 01910.Na in head and neck cancer (HNC)

Aik Choon Tan, Ryan Anderson, Barbara Frederick, David Raben, Antonio Jimeno

Cancer Res (2009) 69 (9_Supplement): 4702.

Published: 01 May 2009

View article titled, Abstract #4702: Pathway-based comparison approach for the identification of responders to the mitotic modulator ON 01910.Na in head and neck cancer (HNC)

Journal Articles

Abstract #3772: The Src inhibitor AZD0530 suppresses head and neck squamous cell carcinoma invasion by disrupting invadopodia activity

Amanda Gatesman Ammer, Laura Kelley, Karen Hayes, Jason Evans, Lesly Ann Lopez-Skinner, Karen Martin, Brian Rothschild, Barbara Frederick, David Raben, Tim Green, Scott Weed

Cancer Res (2009) 69 (9_Supplement): 3772.

Published: 01 May 2009

View article titled, Abstract #3772: The Src inhibitor AZD0530 suppresses head and neck squamous cell carcinoma invasion by disrupting invadopodia activity

Journal Articles

Abstract #3989: Combined Resveratrol and radiation therapy in head and neck cancer

Robert Sclafani, Sunitha Siriwardana, Barbara Frederick, Simone Stahringer, Alpna Tyagi, Antonio Jimeno, Rajesh Agarwal, David Raben

Cancer Res (2009) 69 (9_Supplement): 3989.

Published: 01 May 2009

View article titled, Abstract #3989: Combined Resveratrol and radiation therapy in head and neck cancer

Journal Articles

Abstract #4946: Inhibition of metastatic dissemination following loco-regional control of a primary tumor: examining a novel treatment paradigm with the Src kinase inhibitor AZD0530

Ian Stratford, Brian` Telfer, Tim Green, Paul Elvin, Anderson Ryan, David Raben, Stephen Wedge

Cancer Res (2009) 69 (9_Supplement): 4946.

Published: 01 May 2009

View article titled, Abstract #4946: Inhibition of metastatic dissemination following loco-regional control of a primary tumor: examining a novel treatment paradigm with the Src kinase inhibitor AZD0530

Journal Articles

Abstract #392: The Src inhibitor AZD0530 induces autophagy in head and neck squamous cell carcinoma and non-small cell lung cancer cell lines

Barbara Frederick, Barbara Helfrich, Ashley Fletcher, David Raben

Cancer Res (2009) 69 (9_Supplement): 392.

Published: 01 May 2009

View article titled, Abstract #392: The Src inhibitor AZD0530 induces autophagy in head and neck squamous cell carcinoma and non-small cell lung cancer cell lines

Journal Articles

Metronomic and MTD-based dosing of docetaxel in combination with vandetanib in human head and neck squamous cell carcinoma xenografts

Erica Bradshaw-Pierce, Courtney Steinhauer, David Raben, E Ehrhart, Daniel Gustafson

Cancer Res (2008) 68 (9_Supplement): 4041.

Published: 01 May 2008

View article titled, Metronomic and MTD-based dosing of docetaxel in combination with vandetanib in human head and neck squamous cell carcinoma xenografts

NARROW

Abstract 6161: PARP inhibition enhances radiotherapy of SMAD4 deficient human head and neck squamous cell carcinomas in experimental models

Inhibiting Translation Elongation with SVC112 Suppresses Cancer Stem Cells and Inhibits Growth in Head and Neck Squamous Carcinoma

Abstract 5035: Blockade of EphB4-ephrin-B2 interaction remodels the tumor immune microenvironment in head and neck cancers

Abstract CT123: IMvoke010: Randomized Phase III study of atezolizumab as adjuvant monotherapy after definitive therapy of squamous cell carcinoma of the head and neck (SCCHN)

Inhibition of EphB4–Ephrin-B2 Signaling Reprograms the Tumor Immune Microenvironment in Head and Neck Cancers

Abstract 5209: Overexpression of TGF-β in Smad4 deficient head and neck squamous cell carcinomas promotes myeloid cell infiltration associated with metastatic progression

Abstract 2946: Role of EphB3 receptor in mediating head and neck tumor growth, cell migration, and response to PI3K inhibitor

Abstract 4169: Inhibition of EphB4-ephrin-B2 signaling results in enhanced sensitivity to cetuximab-radiation therapy in head and neck cancers

Abstract 4173: Inhibition of EphB4-ephrinB2 signaling increases efficacy of radiation in pancreatic ductal adenocarcinoma

Abstract 4168: Radioresistant anaplastic thyroid cancers display a unique gene signature and respond to hypofractionated radiotherapy

Abstract 2766: Resistance to radiotherapy and PD-L1 blockade is mediated by TIM-3 upregulation in anti-PD-L1 refractory head and neck cancer

Workshop Report for Cancer Research: Defining the Shades of Gy: Utilizing the Biological Consequences of Radiotherapy in the Development of New Treatment Approaches—Meeting Viewpoint

Hedgehog Signaling Drives Radioresistance and Stroma-Driven Tumor Repopulation in Head and Neck Squamous Cancers

Abstract #5232: Autocrine signaling by FGFs and FGFRs in HNSCC cells

Abstract #4702: Pathway-based comparison approach for the identification of responders to the mitotic modulator ON 01910.Na in head and neck cancer (HNC)

Abstract #3772: The Src inhibitor AZD0530 suppresses head and neck squamous cell carcinoma invasion by disrupting invadopodia activity

Abstract #3989: Combined Resveratrol and radiation therapy in head and neck cancer

Abstract #4946: Inhibition of metastatic dissemination following loco-regional control of a primary tumor: examining a novel treatment paradigm with the Src kinase inhibitor AZD0530

Abstract #392: The Src inhibitor AZD0530 induces autophagy in head and neck squamous cell carcinoma and non-small cell lung cancer cell lines

Metronomic and MTD-based dosing of docetaxel in combination with vandetanib in human head and neck squamous cell carcinoma xenografts

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