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Journal Articles

Antibody-Peptide Epitope Conjugates for Personalized Cancer Therapy

Songfa Zhang, Chuan Yan, David G. Millar, Qiqi Yang, James M. Heather, Adam Langenbucher, Laura T. Morton, Sean Sepulveda, Eric Alpert, Lauren R. Whelton, Dominique T. Zarrella, Mei Guo, Eleanor Minogue, Michael S. Lawrence, Bo R. Rueda, David R. Spriggs, Weiguo Lu, David M. Langenau, Mark Cobbold

Cancer Res (2022) 82 (5): 773–784.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-2200

Published: 03 March 2022

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Includes: Supplementary data

Journal Articles

Abstract 1836: Structural basis for recognition of MUC16 expressed in various cancers

Kwangkook Lee, Kay Perry, Oladapo O. Yeku, David R. Spriggs

Cancer Res (2021) 81 (13_Supplement): 1836.

DOI: https://doi.org/10.1158/1538-7445.AM2021-1836

Published: 01 July 2021

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Journal Articles

Abstract 1776: High-affinity anti-galectin-3 antibodies targeting oncogenic properties in serous ovarian cancer

Dharmarao Thapi, Marina Stasenko, Thomas White, Sven J. Walderich, Noah Feit, Frances Weis-Garcia, David R. Spriggs

Cancer Res (2018) 78 (13_Supplement): 1776.

DOI: https://doi.org/10.1158/1538-7445.AM2018-1776

Published: 01 July 2018

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Journal Articles

Abstract 5587: Novel monoclonal antibodies block N-glycosylation Sites of the MUC16 ectodomain in ovarian carcinoma

Dharmarao Thapi, Alberto Fernandez-Tejada, Abraham J. Axelrod, Nestor Rosales, Xiujun Yan, Marina Stasenko, Sahityasri Thapi, Amy Wang, Samuel J. Danishefsky, David R. Spriggs

Cancer Res (2017) 77 (13_Supplement): 5587.

DOI: https://doi.org/10.1158/1538-7445.AM2017-5587

Published: 01 July 2017

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Journal Articles

Abstract 141: MUC16/CA125 and Epithelial Growth Factor Receptor functionality in ovarian cancer

Amy Wang, Dharmarao Thapi, Nestor Rosales, Xiu Jun Yan, David R. Spriggs

Cancer Res (2015) 75 (15_Supplement): 141.

DOI: https://doi.org/10.1158/1538-7445.AM2015-141

Published: 01 August 2015

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Journal Articles

Abstract 3045: Glycosylation dependence in MUC16/CA125 expression in ovarian cancer..

Dharmarao Thapi, Xiu Jun Yan, Nestor Rosales, David R. Spriggs

Cancer Res (2013) 73 (8_Supplement): 3045.

DOI: https://doi.org/10.1158/1538-7445.AM2013-3045

Published: 15 April 2013

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Journal Articles

Abstract 513: Novel monoclonal antibody detects an intracellular portion of the MUC16 in ovarian carcinoma

Catherine M. Igel, Dharmarao Thapi, Elmer B. Santos, Sho Fujisawa, Katia O. Manova-Todorova, David R. Spriggs

Cancer Res (2012) 72 (8_Supplement): 513.

DOI: https://doi.org/10.1158/1538-7445.AM2012-513

Published: 15 April 2012

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Journal Articles

Abstract 1828: Identification of MUC16/CA125-specific therapeutics through dual fluorescence high throughput screening

Dharmarao Thapi, Sahityasri Thapi, Nestor Rosales, Christophe Antczak, Ouathek Ouerfelli, David R. Spriggs, Hakim Djaballah

Cancer Res (2012) 72 (8_Supplement): 1828.

DOI: https://doi.org/10.1158/1538-7445.AM2012-1828

Published: 15 April 2012

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Journal Articles

Abstract 3033: Identification of the MUC16/CA125 interaction network: Results of a high-throughput yeast two-hybrid screening

Stephan Polterauer, Dharmarao Thapi, Nikolaus Schultz, Ouathek Ouerfelli, Nancy Chen, Nestor Rosales, Xiu Yan, David R. Spriggs

Cancer Res (2012) 72 (8_Supplement): 3033.

DOI: https://doi.org/10.1158/1538-7445.AM2012-3033

Published: 15 April 2012

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Journal Articles

Abstract 1946: Detecting protein-protein interactions between MUC16 CDΔ102 (80AA) and a SKOV-3 cDNA library using yeast two-hybrid screening

Stephan Polterauer, Ryan Parlett, Dharmarao Thapi, Nestor Rosales, David R. Spriggs, Xiu J. Yan

Cancer Res (2011) 71 (8_Supplement): 1946.

DOI: https://doi.org/10.1158/1538-7445.AM2011-1946

Published: 15 April 2011

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Journal Articles

Abstract 2033: Transcription factors that regulate MUC16 expression in ovarian cancer

Dharmarao Thapi, Darcie Binder, Nestor Rosales, Xiu Jun Yan, Alex E. Lash, David R. Spriggs

Cancer Res (2011) 71 (8_Supplement): 2033.

DOI: https://doi.org/10.1158/1538-7445.AM2011-2033

Published: 15 April 2011

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Journal Articles

Abstract 4332: Conditional transgenic mice for the carboxyl-terminus of MUC16

Huasong Tian, David R. Spriggs

Cancer Res (2011) 71 (8_Supplement): 4332.

DOI: https://doi.org/10.1158/1538-7445.AM2011-4332

Published: 15 April 2011

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Journal Articles

Abstract 5503: Dual fluorescence high throughput screen detects MUC16 selective therapeutic candidates

Dharmarao Thapi, Guillaume Normand, Irena D. Ivnitski-Steele, Irina Ostrovnaya, David Shum, David R. Spriggs, Hakim Djaballah

Cancer Res (2010) 70 (8_Supplement): 5503.

DOI: https://doi.org/10.1158/1538-7445.AM10-5503

Published: 15 April 2010

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Journal Articles

Abstract 1940: Successful eradication of established peritoneal ovarian tumors in SCID-beige mice following adoptive transfer of T cells genetically targeted to the MUC16 antigen

Alena A. Chekmasova, Dharmarao Thapi, Yan Nikhamin, Kay J. Park, David R. Spriggs, Renier J. Brentjens

Cancer Res (2010) 70 (8_Supplement): 1940.

DOI: https://doi.org/10.1158/1538-7445.AM10-1940

Published: 15 April 2010

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Journal Articles

MUC16 gene expression in human oarian cncer cells and Cisplatin resistance

Dharmarao Thapi, Siobhan M. Kehoe, Eric Eisenhauer, Jeff Boyd, Jakob Dupont, David R. Spriggs

Cancer Res (2006) 66 (8_Supplement): 881.

Published: 15 April 2006

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Journal Articles

eEF1a2 overexpression has dual function in ovarian epithelial carcinoma

Aliza L. Leiser, Gregory M. Springett, Nestor Rosales, Dharmarao Thapi, David R. Spriggs

Cancer Res (2005) 65 (9_Supplement): 846.

Published: 01 May 2005

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Journal Articles

Selective killing of drug-resistant mammary carcinoma by exploiting the tumor cell ATP viability threshold.

Daniel S. Martin, Alan A. Alfieri, Jason A. Koutcher, David R. Spriggs, Larry Norton, Joseph R. Bertino

Cancer Res (2004) 64 (7_Supplement): 570.

Published: 01 April 2004

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Journal Articles

BRCA1 Up-Regulation Is Associated with Repair-mediated Resistance to cis-Diamminedichloroplatinum(II)

Amreen Husain, Guoshun He, Ennapadam S. Venkatraman, David R. Spriggs

Cancer Res (1998) 58 (6): 1120–1123.

Published: 01 March 1998

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Journal Articles

Posttranscriptional Regulation of Protein Expression in Human Epithelial Carcinoma Cells by Adenine-Uridine-Rich Elements in the 3′-Untranslated Region of Tumor Necrosis Factor-α Messenger RNA

Enhong Wang, Wei-Jun Ma, Carol Aghajanian, David R. Spriggs

Cancer Res (1997) 57 (23): 5426–5433.

Published: 01 December 1997

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Journal Articles

Phospholipase A₂ Activation and Autoinduction of Tumor Necrosis Factor Gene Expression by Tumor Necrosis Factor

David R. Spriggs, Matthew L. Sherman, Kyoko Imamura, Mitsunobu Mohri, Christina Rodriguez, Gregory Robbins, Donald W. Kufe

Cancer Res (1990) 50 (22): 7101–7107.

Published: 01 November 1990

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NARROW

Antibody-Peptide Epitope Conjugates for Personalized Cancer Therapy

Abstract 1836: Structural basis for recognition of MUC16 expressed in various cancers

Abstract 1776: High-affinity anti-galectin-3 antibodies targeting oncogenic properties in serous ovarian cancer

Abstract 5587: Novel monoclonal antibodies block N-glycosylation Sites of the MUC16 ectodomain in ovarian carcinoma

Abstract 141: MUC16/CA125 and Epithelial Growth Factor Receptor functionality in ovarian cancer

Abstract 3045: Glycosylation dependence in MUC16/CA125 expression in ovarian cancer..

Abstract 513: Novel monoclonal antibody detects an intracellular portion of the MUC16 in ovarian carcinoma

Abstract 1828: Identification of MUC16/CA125-specific therapeutics through dual fluorescence high throughput screening

Abstract 3033: Identification of the MUC16/CA125 interaction network: Results of a high-throughput yeast two-hybrid screening

Abstract 1946: Detecting protein-protein interactions between MUC16 CDΔ102 (80AA) and a SKOV-3 cDNA library using yeast two-hybrid screening

Abstract 2033: Transcription factors that regulate MUC16 expression in ovarian cancer

Abstract 4332: Conditional transgenic mice for the carboxyl-terminus of MUC16

Abstract 5503: Dual fluorescence high throughput screen detects MUC16 selective therapeutic candidates

Abstract 1940: Successful eradication of established peritoneal ovarian tumors in SCID-beige mice following adoptive transfer of T cells genetically targeted to the MUC16 antigen

MUC16 gene expression in human oarian cncer cells and Cisplatin resistance

eEF1a2 overexpression has dual function in ovarian epithelial carcinoma

Selective killing of drug-resistant mammary carcinoma by exploiting the tumor cell ATP viability threshold.

BRCA1 Up-Regulation Is Associated with Repair-mediated Resistance to cis-Diamminedichloroplatinum(II)

Posttranscriptional Regulation of Protein Expression in Human Epithelial Carcinoma Cells by Adenine-Uridine-Rich Elements in the 3′-Untranslated Region of Tumor Necrosis Factor-α Messenger RNA

Phospholipase A₂ Activation and Autoinduction of Tumor Necrosis Factor Gene Expression by Tumor Necrosis Factor

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