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David R. Jones
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Journal Articles

Abstract 1978: Circulating rare events as a biomarker of anti-tumoral effect of ketamine therapy in non-small cell lung cancer

Free
Anya Shah, Stephanie Shishido, Jeremy Mason, George W. Fischer, David Amar, Dawn Desiderio, Joseph R. Scarpa, David R. Jones, Amitabh Gulati, Alessia Pedoto, Alessandro De Camilli, Cosmin Guaran, Jacob C. Jackson, Alexandra Lewis, Michelle Zanone, Lucy Nystrom, Howard Scher, Ethan Barnett, Joshua Mincer, Peter Kuhn
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1978.
https://doi.org/10.1158/1538-7445.AM2025-1978
Published: 21 April 2025
View articletitled, Abstract 1978: Circulating rare events as a biomarker of anti-tumoral effect of ketamine therapy in non-small cell lung cancer
Journal Articles

Abstract 548: Histone deacetylase inhibitor, Vorinostat, reverses EGFR-TKI resistance in lung adenocarcinoma via degradation of MET

Free
Choudhary Harsha, Yuan Liu, Whitney S. Brandt, Di He, Manendra B. Lankadasari, Stella Tsui, Nanruoyi Zhou, Brooke Mastrogiacomo, Tetsuhiko Asao, David R. Jones
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 548.
https://doi.org/10.1158/1538-7445.AM2025-548
Published: 21 April 2025
View articletitled, Abstract 548: Histone deacetylase inhibitor, Vorinostat, reverses EGFR-TKI resistance in lung adenocarcinoma via degradation of MET
Journal Articles

Abstract 3256: Circulating tumor DNA as a prognostic biomarker in locally advanced esophageal cancer

Free
Marisa Sewell, Matthew Bott, Katherine Gray, Steve Maron, Yelena Janjigian, Hans Gerdes, Pari Shah, Abraham Wu, Bernard J. Park, David R. Jones, Daniela Molena
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3256.
https://doi.org/10.1158/1538-7445.AM2025-3256
Published: 21 April 2025
View articletitled, Abstract 3256: Circulating tumor DNA as a prognostic biomarker in locally advanced esophageal cancer
Journal Articles

Abstract 5361: Clinical implications of The Cancer Genome Atlas molecular classification system in esophagogastric cancer

Free
Henry Walch, Raktim Borpatragohain, Justin Jee, Walid Chatila, Christopher Fong, Steven B. Maron, Geoffrey Ku, David H. Ilson, Yelena Y. Janjigian, Abraham J. Wu, Pari Shah, Daniel G. Coit, Manjit S. Bains, Valerie W. Rusch, Bernard Park, Matthew Bott, Katherine Gray, David R. Jones, Michael F. Berger, Nikolaus Schultz, Vivian E. Strong, Daniela Molena, Smita Sihag
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5361.
https://doi.org/10.1158/1538-7445.AM2025-5361
Published: 21 April 2025
View articletitled, Abstract 5361: Clinical implications of The Cancer Genome Atlas molecular classification system in esophagogastric cancer
Journal Articles

Abstract 2556: Longitudinal analyses of clinical sequencing data provide novel insights into the evolutionary dynamics of lung adenocarcinoma

Free
Brooke Mastrogiacomo, Elizabeth G. Dunne, Cameron N. Fick, John Nguyen, Jairam Hathwar, Manendra Lankadasari, Yuan Liu, Soo-Ryum Yang, Jason Chang, Walid K. Chatila, Nikolaus Schultz, David R. Jones, Francisco Sanchez-Vega
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2556.
https://doi.org/10.1158/1538-7445.AM2024-2556
Published: 22 March 2024
View articletitled, Abstract 2556: Longitudinal analyses of clinical sequencing data provide novel insights into the evolutionary dynamics of lung adenocarcinoma
Journal Articles

Abstract 5211: Somatic copy number variation as prognostic marker for recurrence in never-smokers with early-stage lung adenocarcinoma

Free
Stijn Vanstraelen, Allison Reiner, Brooke H. Mastrogiacomo, Kay See Tan, Joseph Dycoco, Bernard J. Park, Prasad S. Adusumilli, Matthew J. Bott, David R. Jones, Gaetano Rocco
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5211.
https://doi.org/10.1158/1538-7445.AM2024-5211
Published: 22 March 2024
View articletitled, Abstract 5211: Somatic copy number variation as prognostic marker for recurrence in never-smokers with early-stage lung adenocarcinoma
Journal Articles

Abstract 6596: BRMS1 downregulation alters the tumor microenvironment and induces immunotherapy resistance in lung adenocarcinoma

Free
Manendra B. Lankadasari, Yuan Liu, Brooke Mastrogiacomo, Yingjie Zhu, Elizabeth G. Dunne, Cameron N. Fick, Choudhary Harsha, Jorge S. Reis-Filho, David R. Jones
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6596.
https://doi.org/10.1158/1538-7445.AM2024-6596
Published: 22 March 2024
View articletitled, Abstract 6596: BRMS1 downregulation alters the tumor microenvironment and induces immunotherapy resistance in lung adenocarcinoma
Journal Articles

Abstract 3375: Ultrasensitive ctDNA minimal residual disease monitoring in early NSCLC with PhasED-Seq

Free
James M. Isbell, Bob T. Li, Pedram Razavi, Jorge Reis-Filo, Si-Yang Liu, Pier Selenica, Prasad Adusumilli, Matthew Bott, David R. Jones, Valerie W. Rusch, Smita Sihag, Darren J. Buonocore, Justin Jee, Emily Lebow, Daniel Gomez, Andreas Rimner, Fernando C. Santini, Charles M. Rudin, Jordan E. Eichholz, Andres Martinez, Daphne Alerte, Gregory J. Hogan, Andre Schultz, Ronald P. Schuyler, Alanna Roff, Dustin Hite, Jacob J. Chabon, David M. Kurtz, Ash A. Alizadeh, Maximilian Diehn
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3375.
https://doi.org/10.1158/1538-7445.AM2023-3375
Published: 04 April 2023
View articletitled, Abstract 3375: Ultrasensitive ctDNA minimal residual disease monitoring in early NSCLC with PhasED-Seq
Journal Articles

Abstract 3138: The lung pro-thrombotic niche drives cancer-associated thromboembolism via exosomal ITGB2

Free
Serena Lucotti, Yusuke Ogitani, Candia M. Kenific, Linda Bojmar, Michele Cioffi, Pernille Lauritzen, Henrik Molina, Soren Heissel, Harry B. Lengel, Xiaohong Jing, Haiying Zhang, Irina Matei, Eileen M. O'Reilly, William R. Jarnagin, David R. Jones, James B. Bussel, David Kelsen, Jacqueline F. Bromberg, Diane M. Simeone, David Lyden
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3138.
https://doi.org/10.1158/1538-7445.AM2022-3138
Published: 15 June 2022
View articletitled, Abstract 3138: The lung pro-thrombotic niche drives cancer-associated thromboembolism via exosomal ITGB2
Journal Articles

Abstract 3142: BRMS1 alters the tumor inflammatory signature and immune infiltration in lung adenocarcinoma

Free
Manendra B. Lankadasari, Yuan Liu, Di He, Samhita Bapat, Brooke Mastrogiacomo, Harry B. Lengel, David R. Jones
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3142.
https://doi.org/10.1158/1538-7445.AM2022-3142
Published: 15 June 2022
View articletitled, Abstract 3142: BRMS1 alters the tumor inflammatory signature and immune infiltration in lung adenocarcinoma
Journal Articles

Differential Activity of ATR and WEE1 Inhibitors in a Highly Sensitive Subpopulation of DLBCL Linked to Replication Stress

Free
Lucy A. Young, Lenka Oplustil O'Connor, Christelle de Renty, Margaret H. Veldman-Jones, Thierry Dorval, Zena Wilson, David R. Jones, Deborah Lawson, Rajesh Odedra, Apolinar Maya-Mendoza, Corinne Reimer, Jiri Bartek, Alan Lau, Mark J. O'Connor
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (14): 3762–3775.
https://doi.org/10.1158/0008-5472.CAN-18-2480
Published: 15 July 2019
View articletitled, Differential Activity of ATR and WEE1 Inhibitors in a Highly Sensitive Subpopulation of DLBCL Linked to Replication Stress
Open the PDF for Differential Activity of ATR and WEE1 Inhibitors in a Highly Sensitive Subpopulation of DLBCL Linked to Replication Stress in another window
Includes: Supplementary data
Journal Articles

Abstract CT036: A phase I clinical trial of malignant pleural disease treated with regionally delivered autologous mesothelin-targeted CAR T cells: Safety and efficacy

Free
Prasad S. Adusumilli, Marjorie G. Zauderer, Valerie W. Rusch, Roisin E. O'Cearbhaill, Amy Zhu, Daniel A. Ngai, Erin McGee, Navin K. Chintala, John C. Messinger, Alain Vincent, Elizabeth F. Halton, Claudia Diamonte, John Pineda, Shanu Modi, Stephen B. Solomon, David R. Jones, Renier J. Brentjens, Isabelle Rivière, Michel Sadelain
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT036.
https://doi.org/10.1158/1538-7445.AM2019-CT036
Published: 01 July 2019
View articletitled, Abstract CT036: A phase I clinical trial of malignant pleural disease treated with regionally delivered autologous mesothelin-targeted CAR T cells: Safety and efficacy
Journal Articles

Abstract CT079: Neoadjuvant PD-1 blockade in resectable lung cancer

Free
Patrick M. Forde, Jamie E. Chaft, Kellie N. Smith, Valsamo Anagnostou, Tricia R. Cottrell, Matthew D. Hellmann, Marianna Zahurak, Stephen C. Yang, David R. Jones, Stephen Broderick, Richard J. Battafarano, Moises J. Velez, Natasha Rekhtman, Zachary Olah, Jarushka Naidoo, Kristen A. Marrone, Franco Verde, Haidan Guo, Jiajia Zhang, Justina X. Caushi, Hok Yee Chan, John-William Sidhom, Robert B. Scharpf, James White, Edward Gabrielson, Hao Wang, Gary L. Rosner, Valerie Rusch, Jedd D. Wolchok, Taha Merghoub, Janis M. Taube, Victor E. Velculescu, Suzanne L. Topalian, Julie R. Brahmer, Drew M. Pardoll
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): CT079.
https://doi.org/10.1158/1538-7445.AM2018-CT079
Published: 01 July 2018
View articletitled, Abstract CT079: Neoadjuvant PD-1 blockade in resectable lung cancer
Journal Articles

Abstract LB-154: Pathologic features of response to neoadjuvant anti-PD-1 in resected non-small cell lung carcinoma (NSCLC): A proposal for quantitative immune-related pathologic response criteria (irPRC)

Free
Tricia R. Cottrell, Julie E. Stein, Jamie E. Chaft, Elizabeth D. Thompson, Natasha Rekhtman, Valsamo Anagnostou, Kellie N. Smith, Amy S. Duffield, Robert A. Anders, James M. Isbell, David R. Jones, Jonathan D. Cuda, Richard Battafarano, Stephen C. Yang, Peter B. Illei, Edward Gabrielson, Frederic Askin, Moises Velez, Matthew D. Hellmann, Jennifer L. Sauter, Ludmila Danilova, Victor E. Velculescu, Jedd D. Wolchok, Suzanne L. Topalian, Julie R. Brahmer, Drew M. Pardoll, Ashley Cimino-Mathews, Patrick M. Forde, Janis M. Taube
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-154.
https://doi.org/10.1158/1538-7445.AM2018-LB-154
Published: 01 July 2018
View articletitled, Abstract LB-154: Pathologic features of response to neoadjuvant anti-PD-1 in resected non-small cell lung carcinoma (NSCLC): A proposal for quantitative immune-related pathologic response criteria (irPRC)
Journal Articles

Abstract 4840: SNP rs1052566 (Ala273Val) in BRMS1 variant2 promotes metastasis in lung adenocarcinoma

Free
Neel P. Chudgar, Yuan Liu, Joseph Montecalvo, Marty W. Mayo, Prasad S. Adusumilli, David R. Jones
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4840.
https://doi.org/10.1158/1538-7445.AM2017-4840
Published: 01 July 2017
View articletitled, Abstract 4840: SNP rs1052566 (Ala273Val) in BRMS1 variant2 promotes metastasis in lung adenocarcinoma
Journal Articles

Abstract 3721: A camptothecin-containing nanoparticle-drug conjugate combination with DDR agents provides a novel approach to increasing therapeutic index

Free
Lenka Oplustil O’Connor, Anderson T. Wang, David R. Jones, Rajesh Odedra, Michael Spreadborough, Joanne Wilson, Aaron Smith, Peter Cotton, Jaimini Reens, Jen Barnes, Victoria Sheridan, Scott Eliasof, Andres Tellez, Alan Lau, Claire Sadler, Mark J. O’Connor
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3721.
https://doi.org/10.1158/1538-7445.AM2016-3721
Published: 15 July 2016
View articletitled, Abstract 3721: A camptothecin-containing nanoparticle-drug conjugate combination with DDR agents provides a novel approach to increasing therapeutic index
Journal Articles

CK2α' Drives Lung Cancer Metastasis by Targeting BRMS1 Nuclear Export and Degradation

Free
Yuan Liu, Elianna B. Amin, Marty W. Mayo, Neel P. Chudgar, Peter R. Bucciarelli, Kyuichi Kadota, Prasad S. Adusumilli, David R. Jones
Journal: Cancer Research
Cancer Res (2016) 76 (9): 2675–2686.
https://doi.org/10.1158/0008-5472.CAN-15-2888
Published: 01 May 2016
View articletitled, CK2α' Drives Lung Cancer Metastasis by Targeting BRMS1 Nuclear Export and Degradation
Open the PDF for CK2α' Drives Lung Cancer Metastasis by Targeting BRMS1 Nuclear Export and Degradation in another window
Includes: Supplementary data
Journal Articles

Activin Upregulation by NF-κB Is Required to Maintain Mesenchymal Features of Cancer Stem–like Cells in Non–Small Cell Lung Cancer

Free
J. Jacob Wamsley, Manish Kumar, David F. Allison, Sheena H. Clift, Caitlyn M. Holzknecht, Szymon J. Szymura, Stephen A. Hoang, Xiaojiang Xu, Christopher A. Moskaluk, David R. Jones, Stefan Bekiranov, Marty W. Mayo
Journal: Cancer Research
Cancer Res (2015) 75 (2): 426–435.
https://doi.org/10.1158/0008-5472.CAN-13-2702
Published: 14 January 2015
View articletitled, Activin Upregulation by NF-κB Is Required to Maintain Mesenchymal Features of Cancer Stem–like Cells in Non–Small Cell Lung Cancer
Open the PDF for Activin Upregulation by NF-κB Is Required to Maintain Mesenchymal Features of Cancer Stem–like Cells in Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract A2: Using plexiform neurofibroma preclinical therapeutics to help guide clinical trials

Free
Jianqiang Wu, Edwin Jousma, Tilat Rizvi, Richard Scott Dunn, David R. Jones, Timothy P. Cripe, Mi-Ok Kim, Leigh Marcus, Eva Dombi, Andrea Baldwin, Lauren Meyerson Long, Gillespie Andrea, Patricia Whitcomb, Staci Martin Peron, Brigitte Widemann, David Janhofer, Nancy Ratner
Journal: Cancer Research
Cancer Res (2014) 74 (20_Supplement): A2.
https://doi.org/10.1158/1538-7445.PEDCAN-A2
Published: 09 October 2014
View articletitled, Abstract A2: Using plexiform neurofibroma preclinical therapeutics to help guide clinical trials
Journal Articles

Abstract 2741: Sensitization of temozolomide-mediated glioblastoma cell death by targeting MDM2: Assessment of PD biomarkers, brain penetration, and efficacy in humanized orthotopic xenograft models

Free
Haiyan Wang, Shanbao Cai, Barbara J. Bailey, Lawrence M. Gelbert, M. Reza Saadatzadeh, Aaron A. Cohen-Gadol, Jann N. Sarkaria, Paul Territo, Taxiarchis M. Georgiadis, T. Zachary Gunter, Samy Meroueh, Eric C. Long, David R. Jones, Lindsey D. Mayo, Shannon Harlan, Karen E. Pollok
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2741.
https://doi.org/10.1158/1538-7445.AM2014-2741
Published: 01 October 2014
View articletitled, Abstract 2741: Sensitization of temozolomide-mediated glioblastoma cell death by targeting MDM2: Assessment of PD biomarkers, brain penetration, and efficacy in humanized orthotopic xenograft models