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David R. Bickers
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Journal Articles

Sonic Hedgehog Signaling in Basal Cell Nevus Syndrome

Free
Mohammad Athar, Changzhao Li, Arianna L. Kim, Vladimir S. Spiegelman, David R. Bickers
Journal: Cancer Research
Cancer Res (2014) 74 (18): 4967–4975.
https://doi.org/10.1158/0008-5472.CAN-14-1666
Published: 14 September 2014
View articletitled, Sonic Hedgehog Signaling in Basal Cell Nevus Syndrome
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Journal Articles

Abstract LB-1: An investigator-initiated, phase II randomized, double-blind, placebo-controlled trial of GDC-0449 for prevention of BCCs in basal cell nevus syndrome (BCNS) patients.gg

Free
Jean Y. Tang, Julian M. Mackay-Wiggan, Michelle Aszterbaum, Joselyn Lindgren, Kris Chang, Carol Coppola, Angela Campbell, Anita Chanana, Jackleen Marji, Chris Callahan, Robert Yauch, David R. Bickers, Ervin H. Epstein
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-1.
https://doi.org/10.1158/1538-7445.AM2011-LB-1
Published: 15 April 2011
View articletitled, Abstract LB-1: An investigator-initiated, phase II randomized, double-blind, placebo-controlled trial of GDC-0449 for prevention of BCCs in basal cell nevus syndrome (BCNS) patients.gg
Journal Articles

The hypomorphic Blm allele enhances the development of basal cell carcinomas and rhabdomyosarcomas in the Ptch1 mouse

Free
Jennifer L. Hebert, Lisa D. McDaniel, Yefim Khaimskiy, Levy Kopelovich, David R. Bickers, Roger A. Schultz, Ervin H. Epstein, Jr.
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 604.
Published: 15 April 2006
View articletitled, The hypomorphic Blm allele enhances the development of basal cell carcinomas and rhabdomyosarcomas in the Ptch1 mouse
Journal Articles

Topical CP-31398, a mutant p53-rescuing drug, suppresses the development of ultraviolet B-induced skin cancer in SKH-1 hairless mice

Free
Arianna L. Kim, Yucui Zhu, Xiuwei Tang, Lydia Han, Levy Kopelovich, Mohammad Athar, David R. Bickers
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 628–629.
Published: 01 May 2005
View articletitled, Topical CP-31398, a mutant p53-rescuing drug, suppresses the development of ultraviolet B-induced skin cancer in SKH-1 hairless mice
Journal Articles

Budesonide and a retinoid X receptor-selective ligand bexarotene prevent the development of ultraviolet B-induced skin cancer in SKH-1 hairless mice

Free
Xiuwei Tang, Arianna L. Kim, Huaijie Zhu, Levy Kopelovich, David R. Bickers, Mohammad Athar
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1017.
Published: 01 May 2005
View articletitled, Budesonide and a retinoid X receptor-selective ligand bexarotene prevent the development of ultraviolet B-induced skin cancer in SKH-1 hairless mice
Journal Articles

Basal cell carcinoma in Ptch1 exposed to ionizing radiation - effects of genetic background

Free
Jennifer L. Hebert, Christine Chang, Kevin Cheng, Yefim Khaimskiy, Levy Kopelovich, David R. Bickers, Yuichi Wakabayashi, Allan Balmain, Ervin H. Epstein, Jr.
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 247.
Published: 01 May 2005
View articletitled, Basal cell carcinoma in Ptch1 exposed to ionizing radiation - effects of genetic background
Journal Articles

Inhibition of Smoothened Signaling Prevents Ultraviolet B-Induced Basal Cell Carcinomas through Regulation of Fas Expression and Apoptosis

Free
Mohammad Athar, Chengxin Li, Xiuwei Tang, Sumin Chi, Xiaoli Zhang, Arianna L. Kim, Stephen K. Tyring, Levy Kopelovich, Jennifer Hebert, Ervin H. Epstein, Jr., David R. Bickers, Jingwu Xie
Journal: Cancer Research
Cancer Res (2004) 64 (20): 7545–7552.
https://doi.org/10.1158/0008-5472.CAN-04-1393
Published: 15 October 2004
View articletitled, Inhibition of Smoothened Signaling Prevents Ultraviolet B-Induced Basal Cell Carcinomas through Regulation of Fas Expression and Apoptosis
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Journal Articles

Evidence for Lack of Enhanced Hedgehog Target Gene Expression in Common Extracutaneous Tumors

Free
Zhilan Hu, Jeannette M. Bonifas, Geraldine Aragon, Levy Kopelovich, Yu Liang, Shoichiro Ohta, Mark A. Israel, David R. Bickers, Michelle Aszterbaum, Ervin H. Epstein, Jr.
Journal: Cancer Research
Cancer Res (2003) 63 (5): 923–928.
Published: 01 March 2003
View articletitled, Evidence for Lack of Enhanced Hedgehog Target Gene Expression in Common Extracutaneous Tumors
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Journal Articles

Environmental Skin Cancer: Mechanisms, Models and Human Relevance

Free
Hasan Mukhtar, David R. Bickers
Journal: Cancer Research
Cancer Res (1993) 53 (14): 3439–3442.
Published: 01 July 1993
View articletitled, Environmental Skin Cancer: Mechanisms, Models and Human Relevance
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Journal Articles

Immunogenetic Influences on the Initiation Stage of the Cutaneous Chemical Carcinogenesis Pathway

Free
Craig A. Elmets, Syed I. A. Zaidi, David R. Bickers, Hasan Mukhtar
Journal: Cancer Research
Cancer Res (1992) 52 (21): 6106–6109.
Published: 01 November 1992
View articletitled, Immunogenetic Influences on the Initiation Stage of the Cutaneous Chemical Carcinogenesis Pathway
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Journal Articles

Exceptional Activity of Tannic Acid among Naturally Occurring Plant Phenols in Protecting against 7,12-Dimethylbenz(a)anthracene-, Benzo(a)pyrene-, 3-Methylcholanthrene-, and N-Methyl-N-nitrosourea-induced Skin Tumorigenesis in Mice

Free
Hasan Mukhtar, Mukul Das, Wasiuddin A. Khan, Zhi Y. Wang, Daniel P. Bik, David R. Bickers
Journal: Cancer Research
Cancer Res (1988) 48 (9): 2361–2365.
Published: 01 May 1988
View articletitled, Exceptional Activity of Tannic Acid among Naturally Occurring Plant Phenols in Protecting against 7,12-Dimethylbenz(a)anthracene-, Benzo(a)pyrene-, 3-Methylcholanthrene-, and N-Methyl-N-nitrosourea-induced Skin Tumorigenesis in Mice
Open the PDF for Exceptional Activity of Tannic Acid among Naturally Occurring Plant Phenols in Protecting against 7,12-Dimethylbenz(a)anthracene-, Benzo(a)pyrene-, 3-Methylcholanthrene-, and N-Methyl-N-nitrosourea-induced Skin Tumorigenesis in Mice in another window
Journal Articles

Inhibition of Epidermal Xenobiotic Metabolism in SENCAR Mice by Naturally Occurring Plant Phenols

Free
Mukul Das, Hasan Mukhtar, Daniel P. Bik, David R. Bickers
Journal: Cancer Research
Cancer Res (1987) 47 (3): 760–766.
Published: 01 February 1987
View articletitled, Inhibition of Epidermal Xenobiotic Metabolism in SENCAR Mice by Naturally Occurring Plant Phenols
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Journal Articles

Inhibition of Polycyclic Aromatic Hydrocarbon-DNA Adduct Formation in Epidermis and Lungs of SENCAR Mice by Naturally Occurring Plant Phenols

Free
Mukul Das, Wasiuddin A. Khan, Parthasarathy Asokan, David R. Bickers, Hasan Mukhtar
Journal: Cancer Research
Cancer Res (1987) 47 (3): 767–773.
Published: 01 February 1987
View articletitled, Inhibition of Polycyclic Aromatic Hydrocarbon-DNA Adduct Formation in Epidermis and Lungs of SENCAR Mice by Naturally Occurring Plant Phenols
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Journal Articles

Inhibition of 3-Methylcholanthrene-induced Skin Tumorigenicity in BALB/c Mice by Chronic Oral Feeding of Trace Amounts of Ellagic Acid in Drinking Water

Free
Hasan Mukhtar, Mukul Das, David R. Bickers
Journal: Cancer Research
Cancer Res (1986) 46 (5): 2262–2265.
Published: 01 May 1986
View articletitled, Inhibition of 3-Methylcholanthrene-induced Skin Tumorigenicity in BALB/c Mice by Chronic Oral Feeding of Trace Amounts of Ellagic Acid in Drinking Water
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Journal Articles

Photoenhancement of Lipid Peroxidation Associated with the Generation of Reactive Oxygen Species in Hepatic Microsomes of Hematoporphyrin Derivative-treated Rats

Free
Mukul Das, Hasan Mukhtar, Emily R. Greenspan, David R. Bickers
Journal: Cancer Research
Cancer Res (1985) 45 (12_Part_1): 6328–6330.
Published: 01 December 1985
View articletitled, Photoenhancement of Lipid Peroxidation Associated with the Generation of Reactive Oxygen Species in Hepatic Microsomes of Hematoporphyrin Derivative-treated Rats
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Journal Articles

Role of Active Oxygen Species in the Photodestruction of Microsomal Cytochrome P-450 and Associated Monooxygenases by Hematoporphyrin Derivative in Rats

Free
Mukul Das, Rakesh Dixit, Hasan Mukhtar, David R. Bickers
Journal: Cancer Research
Cancer Res (1985) 45 (2): 608–615.
Published: 01 February 1985
View articletitled, Role of Active Oxygen Species in the Photodestruction of Microsomal Cytochrome P-450 and Associated Monooxygenases by Hematoporphyrin Derivative in Rats
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Journal Articles

Clotrimazole, an Inhibitor of Epidermal Benzo(a)pyrene Metabolism and DNA Binding and Carcinogenicity of the Hydrocarbon

Free
Hasan Mukhtar, Benjamin J. Del Tito, Jr., Mukul Das, Evan P. Cherniack, Andrew D. Cherniack, David R. Bickers
Journal: Cancer Research
Cancer Res (1984) 44 (10): 4233–4240.
Published: 01 October 1984
View articletitled, Clotrimazole, an Inhibitor of Epidermal Benzo(a)pyrene Metabolism and DNA Binding and Carcinogenicity of the Hydrocarbon
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