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David M. Wilson
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Journal Articles

Abstract 1822: Selective inhibition of ZCCHC11/ZCCHC6 TUTases with genetic and pharmacological tools supports a role in glioblastoma cell growth

Robinson Triboulet, Khikmet Sadykov, Jessica L. Johnson, Andrew R. Snyder, Sarah K. Knutson, Pavan Kumar, Christopher B. Mayo, Dillon Hawley, Andrew Madanjian, Ross L. Stein, David M. Wilson, Darren M. Harvey, Shomir Ghosh, Robert M. Campbell
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1822.
https://doi.org/10.1158/1538-7445.AM2022-1822
Published: 15 June 2022
View article titled, Abstract 1822: Selective inhibition of ZCCHC11/ZCCHC6 TUTases with genetic and pharmacological tools supports a role in glioblastoma cell growth
Journal Articles

Endonuclease FEN1 Coregulates ERα Activity and Provides a Novel Drug Interface in Tamoxifen-Resistant Breast Cancer

Koen D. Flach, Manikandan Periyasamy, Ajit Jadhav, Dorjbal Dorjsuren, Joseph C. Siefert, Theresa E. Hickey, Mark Opdam, Hetal Patel, Sander Canisius, David M. Wilson, III, Maria Donaldson Collier, Stefan Prekovic, Marja Nieuwland, Roelof J.C. Kluin, Alexey V. Zakharov, Jelle Wesseling, Lodewyk F.A. Wessels, Sabine C. Linn, Wayne D. Tilley, Anton Simeonov, Simak Ali, Wilbert Zwart
Journal: Cancer Research
Cancer Res (2020) 80 (10): 1914–1926.
https://doi.org/10.1158/0008-5472.CAN-19-2207
Published: 15 May 2020
View article titled, Endonuclease FEN1 Coregulates ERα Activity and Provides a Novel Drug Interface in Tamoxifen-Resistant Breast Cancer
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Includes: Supplementary data
Journal Articles

Abstract 2388: Deciphering the role of APE1 protein variants in disease etiology

Jennifer Illuzzi, Nicole A. Harris, Brittney A. Manvilla, Daemyung Kim, Mengxia Li, Alexander C. Drohat, David M. Wilson
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2388.
https://doi.org/10.1158/1538-7445.AM2014-2388
Published: 01 October 2014
View article titled, Abstract 2388: Deciphering the role of APE1 protein variants in disease etiology
Journal Articles

Abstract 3337: Modulating the APE1/NPM1 interaction in cancer.

Mattia Poletto, Dorjbal Dorjsuren, Lisa Lirussi, Carlo Vascotto, Pasqualina L. Scognamiglio, Daniela Marasco, Ajit Jadhav, David J. Maloney, Anton Simeonov, David M. Wilson, Gianluca Tell
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3337.
https://doi.org/10.1158/1538-7445.AM2013-3337
Published: 15 April 2013
View article titled, Abstract 3337: Modulating the APE1/NPM1 interaction in cancer.
Journal Articles

Hyperpolarized 13C-Pyruvate Magnetic Resonance Reveals Rapid Lactate Export in Metastatic Renal Cell Carcinomas

Kayvan R. Keshari, Renuka Sriram, Bertram L. Koelsch, Mark Van Criekinge, David M. Wilson, John Kurhanewicz, Zhen J. Wang
Journal: Cancer Research
Cancer Res (2013) 73 (2): 529–538.
https://doi.org/10.1158/0008-5472.CAN-12-3461
Published: 16 January 2013
View article titled, Hyperpolarized <sup>13</sup>C-Pyruvate Magnetic Resonance Reveals Rapid Lactate Export in Metastatic Renal Cell Carcinomas
Open the PDF for Hyperpolarized <sup>13</sup>C-Pyruvate Magnetic Resonance Reveals Rapid Lactate Export in Metastatic Renal Cell Carcinomas in another window
Includes: Supplementary data
Journal Articles

Abstract LB-263: Synthetic lethal targeting of PTEN-associated homologous recombination (HR) deficient melanoma cells by human apurinic/apyrimidinic endonuclease (APE1) inhibitors

Rachel M. Abbotts, Rebeka Sultana, Claire Seedhouse, Poulam M. Patel, David M. Wilson, Srinivasan Madhusudan
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-263.
https://doi.org/10.1158/1538-7445.AM2012-LB-263
Published: 15 April 2012
View article titled, Abstract LB-263: Synthetic lethal targeting of PTEN-associated homologous recombination (HR) deficient melanoma cells by human apurinic/apyrimidinic endonuclease (APE1) inhibitors
Journal Articles

Abstract 687: Structure-based design, discovery, and pharmacological profiling of human AP endonuclease (APE1) inhibitors for cancer therapy

Mohammed Z. Mohammed, Vaddadi N. Vyjayanti, Charles Laughton, Lodewijk Dekker, Peter M. Fischer, David M. Wilson, Srinivasan Madhusudan
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 687.
https://doi.org/10.1158/1538-7445.AM10-687
Published: 15 April 2010
View article titled, Abstract 687: Structure-based design, discovery, and pharmacological profiling of human AP endonuclease (APE1) inhibitors for cancer therapy
Journal Articles

Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic BRAF by the Kinase Inhibitor SB-590885

Alastair J. King, Denis R. Patrick, Roberta S. Batorsky, Maureen L. Ho, Hieu T. Do, Shu Yun Zhang, Rakesh Kumar, David W. Rusnak, Andrew K. Takle, David M. Wilson, Erin Hugger, Lifu Wang, Florian Karreth, Julie C. Lougheed, Jae Lee, David Chau, Thomas J. Stout, Earl W. May, Cynthia M. Rominger, Michael D. Schaber, Lusong Luo, Ami S. Lakdawala, Jerry L. Adams, Rooja G. Contractor, Keiran S.M. Smalley, Meenhard Herlyn, Michael M. Morrissey, David A. Tuveson, Pearl S. Huang
Journal: Cancer Research
Cancer Res (2006) 66 (23): 11100–11105.
https://doi.org/10.1158/0008-5472.CAN-06-2554
Published: 04 December 2006
View article titled, Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic <em>BRAF</em> by the Kinase Inhibitor SB-590885
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Includes: Supplementary data
Journal Articles

Telomere Repeat Binding Factor 2 Interacts with Base Excision Repair Proteins and Stimulates DNA Synthesis by DNA Polymerase β

Meltem Muftuoglu, Heng Kuan Wong, Syed Z. Imam, David M. Wilson, III, Vilhelm A. Bohr, Patricia L. Opresko
Journal: Cancer Research
Cancer Res (2006) 66 (1): 113–124.
https://doi.org/10.1158/0008-5472.CAN-05-2742
Published: 05 January 2006
View article titled, Telomere Repeat Binding Factor 2 Interacts with Base Excision Repair Proteins and Stimulates DNA Synthesis by DNA Polymerase β
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Journal Articles

A novel, potent and selective small molecule inhibitor of B-Raf kinase, SB-590885, inhibits signal transduction and growth of cells bearing the B-Raf V600E mutation

Alastair J. King, Denis R. Patrick, Roberta S. Batorsky, Maureen L. Ho, Hieu T. Do, David W. Rusnak, Andrew K. Takle, David M. Wilson, Lifu Wang, Florian Karreth, Michael D. Schaber, John J. Voycik, Lusong Luo, Ami S. Lakdawala, Jerry L. Adams, Keiran S. M. Smalley, Meenhard Herlyn, David A. Tuveson, Pearl S. Huang
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1250.
Published: 01 May 2005
View article titled, A novel, potent and selective small molecule inhibitor of B-Raf kinase, SB-590885, inhibits signal transduction and growth of cells bearing the B-Raf V600E mutation
Journal Articles

Ape1 repair activities on complex DNA structures

David M. Wilson, III
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 418–419.
Published: 01 May 2005
View article titled, Ape1 repair activities on complex DNA structures
Journal Articles

Disparity between DNA Base Excision Repair in Yeast and Mammals: Translational Implications

Mark R. Kelley, Yoke W. Kow, David M. Wilson, III
Journal: Cancer Research
Cancer Res (2003) 63 (3): 549–554.
Published: 01 February 2003
View article titled, Disparity between DNA Base Excision Repair in Yeast and Mammals: <subtitle>Translational Implications</subtitle>
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