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David L. Brautigan
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Journal Articles

Abstract 2981: Biased activation of PP2A through selective heterotrimer binding and stabilization

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Daniel Leonard, Wei Huang, Sudeh Izadmehr, Caitlin M. O'Connor, Danica D. Wiredja, Zhizhi Wang, Nilesh Zaware, Daniela M. Schlatzer, Stefan Schuchner, Janna Kiselar, Yinghua Chen, Nikhil Vasireddi, Abbey L. Perl, Matthew D. Glasky, Wenqing Xu, David L. Brautigan, Egon Ogris, Derek J. Taylor, Goutham Narla
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2981.
https://doi.org/10.1158/1538-7445.AM2020-2981
Published: 15 August 2020
View articletitled, Abstract 2981: Biased activation of PP2A through selective heterotrimer binding and stabilization
Journal Articles

Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer

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Kimberly McClinch, Rita A. Avelar, David Callejas, Sudeh Izadmehr, Danica Wiredja, Abbey Perl, Jaya Sangodkar, David B. Kastrinsky, Daniela Schlatzer, Maxwell Cooper, Janna Kiselar, Agnes Stachnik, Shen Yao, Divya Hoon, Daniel McQuaid, Nilesh Zaware, Yixuan Gong, David L. Brautigan, Stephen R. Plymate, Cynthia C.T. Sprenger, William K. Oh, Alice C. Levine, Alexander Kirschenbaum, John P. Sfakianos, Rosalie Sears, Analisa DiFeo, Yiannis Ioannou, Michael Ohlmeyer, Goutham Narla, Matthew D. Galsky
Journal: Cancer Research
Cancer Res (2018) 78 (8): 2065–2080.
https://doi.org/10.1158/0008-5472.CAN-17-0123
Published: 12 April 2018
View articletitled, Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer
Open the PDF for Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Phosphorylation of RalB Is Important for Bladder Cancer Cell Growth and Metastasis

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Hong Wang, Charles Owens, Nidhi Chandra, Mark R. Conaway, David L. Brautigan, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2010) 70 (21): 8760–8769.
https://doi.org/10.1158/0008-5472.CAN-10-0952
Published: 31 October 2010
View articletitled, Phosphorylation of RalB Is Important for Bladder Cancer Cell Growth and Metastasis
Open the PDF for Phosphorylation of RalB Is Important for Bladder Cancer Cell Growth and Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 311: Phosphorylation of RalB by PKC regulates its intracellular distribution and promotion of bladder tumor growth

Free
Hong Wang, Xuejiao Wang, Charles Owens, Nidhi Chandra, Mark R. Conaway, David L. Brautigan, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 311.
https://doi.org/10.1158/1538-7445.AM10-311
Published: 15 April 2010
View articletitled, Abstract 311: Phosphorylation of RalB by PKC regulates its intracellular distribution and promotion of bladder tumor growth
Journal Articles

Human Melanoma Cytolysis by Combined Inhibition of Mammalian Target of Rapamycin and Vascular Endothelial Growth Factor/Vascular Endothelial Growth Factor Receptor-2

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Kerrington R. Molhoek, Heinrich Griesemann, Jianfen Shu, Jeffrey E. Gershenwald, David L. Brautigan, Craig L. Slingluff, Jr.
Journal: Cancer Research
Cancer Res (2008) 68 (11): 4392–4397.
https://doi.org/10.1158/0008-5472.CAN-07-5844
Published: 02 June 2008
View articletitled, Human Melanoma Cytolysis by Combined Inhibition of Mammalian Target of Rapamycin and Vascular Endothelial Growth Factor/Vascular Endothelial Growth Factor Receptor-2
Open the PDF for Human Melanoma Cytolysis by Combined Inhibition of Mammalian Target of Rapamycin and Vascular Endothelial Growth Factor/Vascular Endothelial Growth Factor Receptor-2 in another window
Journal Articles

Protein Phosphatase-1α Regulates Centrosome Splitting through Nek2

Free
Jun Mi, Changyue Guo, David L. Brautigan, James M. Larner
Journal: Cancer Research
Cancer Res (2007) 67 (3): 1082–1089.
https://doi.org/10.1158/0008-5472.CAN-06-3071
Published: 05 February 2007
View articletitled, Protein Phosphatase-1α Regulates Centrosome Splitting through Nek2
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Journal Articles

Differentiation-induced Changes in Protein-Tyrosine Phosphatase Activity and Commensurate Expression of CD45 in Human Leukemia Cell Lines

Free
Marina Buzzi, Li Lu, Anthony J. Lombardi, Jr., Marshall R. Posner, David L. Brautigan, Lauren D. Fast, A. Raymond Frackelton, Jr.
Journal: Cancer Research
Cancer Res (1992) 52 (14): 4027–4035.
Published: 01 July 1992
View articletitled, Differentiation-induced Changes in Protein-Tyrosine Phosphatase Activity and Commensurate Expression of CD45 in Human Leukemia Cell Lines
Open the PDF for Differentiation-induced Changes in Protein-Tyrosine Phosphatase Activity and Commensurate Expression of CD45 in Human Leukemia Cell Lines in another window