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David J. McConkey
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Journal Articles

Abstract 5774: Enhancing urothelial carcinoma treatment with nectin-4-PET: A predictor of enfortumab vedotin efficacy

Akhilesh Mishra, Ajay K. Sharma, Kuldeep Gupta, Burles A. Johnson, Jeannie Hoffman-Censits, David J. McConkey, Sridhar Nimmagadda
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5774.
https://doi.org/10.1158/1538-7445.AM2025-5774
Published: 21 April 2025
View articletitled, Abstract 5774: Enhancing urothelial carcinoma treatment with nectin-4-PET: A predictor of enfortumab vedotin efficacy
Journal Articles

Abstract 2579: A nectin-4 PET radiotracer for pharmacodynamic evaluation of enfortumab vedotin (EV) therapy in urothelial carcinoma

Akhilesh Mishra, Ajay K. Sharma, Kuldeep Gupta, Burles A. Johnson, David J. McConkey, Jeannie Hoffman-Censits, Sridhar Nimmagadda
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2579.
https://doi.org/10.1158/1538-7445.AM2024-2579
Published: 22 March 2024
View articletitled, Abstract 2579: A nectin-4 PET radiotracer for pharmacodynamic evaluation of enfortumab vedotin (EV) therapy in urothelial carcinoma
Journal Articles

Abstract 612: Control of the Basal Molecular Subtype of Murine Bladder Cancer by Adaptive Immunity

Burles Avner Johnson, Mingxiao Feng, Woonyoung Choi, Gabriela Colocho, Alyssa Arbuiso, Samuel Jin, Adam K. Aragaki, Charles Ruland, Stanley Rapiey, Noah M. Hahn, David J. McConkey
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 612.
https://doi.org/10.1158/1538-7445.AM2023-612
Published: 04 April 2023
View articletitled, Abstract 612: Control of the Basal Molecular Subtype of Murine Bladder Cancer by Adaptive Immunity
Journal Articles

Abstract 970: Gender-specific stratification of survival following immune checkpoint inhibitor therapy based on intratumoral expression of a B cell gene signature

Adam K. Aragaki, Jean Hoffman-Censits, Noah M. Hahn, David J. McConkey, Burles Avner Johnson
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 970.
https://doi.org/10.1158/1538-7445.AM2021-970
Published: 01 July 2021
View articletitled, Abstract 970: Gender-specific stratification of survival following immune checkpoint inhibitor therapy based on intratumoral expression of a B cell gene signature
Journal Articles

Abstract 2765: The indoleamine 2,3 dioxygenase-1 pathway drives intratumoral B cell maintenance

Burles Avner Johnson, Adam K. Aragaki, Donna M. Williams, Ophelia Rogers, Li Luo, Lingling Xian, Lionel Chia, Noah M. Hahn, Stephen Desiderio, Theodore S. Johnson, David J. McConkey, Linda M.S. Resar
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2765.
https://doi.org/10.1158/1538-7445.AM2021-2765
Published: 01 July 2021
View articletitled, Abstract 2765: The indoleamine 2,3 dioxygenase-1 pathway drives intratumoral B cell maintenance
Journal Articles

Abstract 4973: The immunosuppressive tumor microenvironment of metastatic osteosarcoma inhibits the cytotoxic effect of tumor-infiltrating lymphocytes

John A. Ligon, Teniola F. Oke, Woonyoung Choi, Megan H. Fong, Adam Levin, Daniel S. Rhee, Carol D. Morris, Nicholas Siegel, Emily H. Hsieu, Christian F. Meyer, David J. McConkey, Robert A. Anders, Drew M. Pardoll, Nicolas J. Llosa
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4973.
https://doi.org/10.1158/1538-7445.AM2019-4973
Published: 01 July 2019
View articletitled, Abstract 4973: The immunosuppressive tumor microenvironment of metastatic osteosarcoma inhibits the cytotoxic effect of tumor-infiltrating lymphocytes
Journal Articles

Abstract 3689: Identification of candidate therapeutic targets in BCG unresponsive bladder cancer- inflammatory subtypes of BCG unresponsive bladder cancer

Woonyoung Choi, Roger Li, Chinedu Mmeje, I-ling Lee, Shanna Pretzsch, Jolanta Bondaruk, Max Kates, Trinity Bivalacqua, Bogdan Czerniak, Ashish M. Kamat, Colin Dinney, Peter Black, David J. McConkey
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3689.
https://doi.org/10.1158/1538-7445.AM2018-3689
Published: 01 July 2018
View articletitled, Abstract 3689: Identification of candidate therapeutic targets in BCG unresponsive bladder cancer- inflammatory subtypes of BCG unresponsive bladder cancer
Journal Articles

Abstract 1836: Global gene expression profiles from bladder tumor FFPE samples

Varun Bagai, Jeoffrey Schageman, Kelli Bramlett, David J. McConkey, Woonyoung Choi
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1836.
https://doi.org/10.1158/1538-7445.AM2016-1836
Published: 15 July 2016
View articletitled, Abstract 1836: Global gene expression profiles from bladder tumor FFPE samples
Journal Articles

Abstract A1-68: The long noncoding RNA SNHG18 promotes PPARγ function and luminal gene expression in muscle-invasive bladder cancer

Andrea E. Ochoa, Jianping Zhang, Woonyoung Choi, Gabriel G. Malouf, Erika J. Thompson, John N. Weinstein, Nizar M. Tannir, Colin Dinney, David J. McConkey, Xiaoping Su
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_1): A1-68.
https://doi.org/10.1158/1538-7445.TRANSCAGEN-A1-68
Published: 15 November 2015
View articletitled, Abstract A1-68: The long noncoding RNA SNHG18 promotes PPARγ function and luminal gene expression in muscle-invasive bladder cancer
Journal Articles

Abstract 4427: Apoptosis, autophagy and ATP: The dynamic interaction of cellular ATP and drug resistance in MET amplified gastric cancer

Rebecca Dunbar Schroeder, David Hong, David J. McConkey
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4427.
https://doi.org/10.1158/1538-7445.AM2015-4427
Published: 01 August 2015
View articletitled, Abstract 4427: Apoptosis, autophagy and ATP: The dynamic interaction of cellular ATP and drug resistance in MET amplified gastric cancer
Journal Articles

Abstract 2969: Progress in The Cancer Genome Atlas bladder cancer project

John N. Weinstein, Jaegil Kim, Chad J. Creighton, Rehan Akbani, Katherine A. Hoadley, William Y. Kim, Margaret B. Morgan, Toshinori Hinoue, Andrew Cherniack, Xiaoping Su, Andrew J. Mungall, Michael C. Ryan, Dean F. Bajorin, Jonathan E. Rosenberg, Bogdan Czerniak, Donna Hansel, Victor E. Reuter, Brian D. Robinson, Hikmat A. Al-Ahmadie, Jeffrey S. Damrauer, Wei Zhang, Yuexin Liu, Dmitry R. Gordenin, Joshua M. Stuart, Nikolaus Schultz, Gordon Robertson, Steven JM Jones, Raju R. Kucherlapati, David J. McConkey, Peter W. Laird, Gordon B. Mills, David J. Kwiatkowski, Seth P. Lerner, TCGA Bladder Cancer Working Group, TCGA Research Network
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2969.
https://doi.org/10.1158/1538-7445.AM2015-2969
Published: 01 August 2015
View articletitled, Abstract 2969: Progress in The Cancer Genome Atlas bladder cancer project
Journal Articles

Abstract CT241: Gene expression profiling in the context of neoadjuvant chemotherapy with DDMVAC+B (dose dense methotrexate, vinblastine, doxorubicin, cisplatin, and bevacizumab) can predict clinical outcomes and tumor biology

Arlene O. Siefker-Radtke, Woonyoung Choi, John Melquist, Yu Shen, Ashish Kamat, Surena Matin, Randall Millikan, Colin P. Dinney, Bodgan A. Czernial, David J. McConkey
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): CT241.
https://doi.org/10.1158/1538-7445.AM2014-CT241
Published: 01 October 2014
View articletitled, Abstract CT241: Gene expression profiling in the context of neoadjuvant chemotherapy with DDMVAC+B (dose dense methotrexate, vinblastine, doxorubicin, cisplatin, and bevacizumab) can predict clinical outcomes and tumor biology
Journal Articles

Galectin-3 Contributes to Melanoma Growth and Metastasis via Regulation of NFAT1 and Autotaxin

Russell R. Braeuer, Maya Zigler, Takafumi Kamiya, Andrey S. Dobroff, Li Huang, Woonyoung Choi, David J. McConkey, Einav Shoshan, Aaron K. Mobley, Renduo Song, Avraham Raz, Menashe Bar-Eli
Journal: Cancer Research
Cancer Res (2012) 72 (22): 5757–5766.
https://doi.org/10.1158/0008-5472.CAN-12-2424
Published: 14 November 2012
View articletitled, Galectin-3 Contributes to Melanoma Growth and Metastasis via Regulation of NFAT1 and Autotaxin
Open the PDF for Galectin-3 Contributes to Melanoma Growth and Metastasis via Regulation of NFAT1 and Autotaxin in another window
Includes: Supplementary data
Journal Articles

Abstract 4578: Identification of a gene expression signature that is associated with dependency on FGFR3 rather than EGFR in bladder cancer cells

Tiewei Cheng, Beat Roth, David J. McConkey
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4578.
https://doi.org/10.1158/1538-7445.AM2012-4578
Published: 15 April 2012
View articletitled, Abstract 4578: Identification of a gene expression signature that is associated with dependency on FGFR3 rather than EGFR in bladder cancer cells
Journal Articles

Abstract LB-472: p63 inhibits epithelial - mesenchymal transition by promoting the expression of miR205 in human bladder cancer cells

Mai N. Tran, Woonyoung Choi, Neema Navai, Matthew F. Wszolek, I-ling C. Lee, Arlene O. Siefker-Radtke, David J. McConkey
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-472.
https://doi.org/10.1158/1538-7445.AM2012-LB-472
Published: 15 April 2012
View articletitled, Abstract LB-472: p63 inhibits epithelial - mesenchymal transition by promoting the expression of miR205 in human bladder cancer cells
Journal Articles

Abstract 234: Fibroblast growth factor receptor (FGFR)-3 as a suitable target in bladder cancer

Kilian M. Gust, David J. McConkey, Paul K. Hegarty, Jolanta E. Bondaruk, Bogdan A. Czerniak, Colin P. Dinney, Peter C. Black
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 234.
https://doi.org/10.1158/1538-7445.AM2011-234
Published: 15 April 2011
View articletitled, Abstract 234: Fibroblast growth factor receptor (FGFR)-3 as a suitable target in bladder cancer
Journal Articles

Abstract 3920: EphA2 transcription is regulated by activation of Ras / MEK2 / cytoplasmic ERK pathway in pancreatic cancer

Pavel A. Levin, Thiruvengadam Arumugam, David J. McConkey, Shrikanth Reddy, Craig D. Logsdon
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3920.
https://doi.org/10.1158/1538-7445.AM10-3920
Published: 15 April 2010
View articletitled, Abstract 3920: EphA2 transcription is regulated by activation of Ras / MEK2 / cytoplasmic ERK pathway in pancreatic cancer
Journal Articles

Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer

Thiruvengadam Arumugam, Vijaya Ramachandran, Keith F. Fournier, Huamin Wang, Lauren Marquis, James L. Abbruzzese, Gary E. Gallick, Craig D. Logsdon, David J. McConkey, Woonyoung Choi
Journal: Cancer Research
Cancer Res (2009) 69 (14): 5820–5828.
https://doi.org/10.1158/0008-5472.CAN-08-2819
Published: 15 July 2009
View articletitled, Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer
Open the PDF for Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Control of HIF-1α Expression by eIF2α Phosphorylation–Mediated Translational Repression

Keyi Zhu, WaiKin Chan, John Heymach, Miles Wilkinson, David J. McConkey
Journal: Cancer Research
Cancer Res (2009) 69 (5): 1836–1843.
https://doi.org/10.1158/0008-5472.CAN-08-4103
Published: 02 March 2009
View articletitled, Control of HIF-1α Expression by eIF2α Phosphorylation–Mediated Translational Repression
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Includes: Supplementary data
Journal Articles

Gefitinib Reverses TRAIL Resistance in Human Bladder Cancer Cell Lines via Inhibition of AKT-Mediated X-Linked Inhibitor of Apoptosis Protein Expression

Marissa Shrader, Maria Simona Pino, Laura Lashinger, Menashe Bar-Eli, Liana Adam, Colin P.N. Dinney, David J. McConkey
Journal: Cancer Research
Cancer Res (2007) 67 (4): 1430–1435.
https://doi.org/10.1158/0008-5472.CAN-06-1224
Published: 16 February 2007
View articletitled, Gefitinib Reverses TRAIL Resistance in Human Bladder Cancer Cell Lines via Inhibition of AKT-Mediated X-Linked Inhibitor of Apoptosis Protein Expression
Open the PDF for Gefitinib Reverses TRAIL Resistance in Human Bladder Cancer Cell Lines via Inhibition of AKT-Mediated X-Linked Inhibitor of Apoptosis Protein Expression in another window