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Journal Articles

Abstract 1113: NUC-3373 potentiates immune-mediated cytotoxicity of CRC cells

Oliver James Read, Jennifer Bré, David J. Harrison

Cancer Res (2022) 82 (12_Supplement): 1113.

DOI: https://doi.org/10.1158/1538-7445.AM2022-1113

Published: 15 June 2022

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Journal Articles

Abstract 1835: NUC-3373 targets the DNA-directed pathway more effectively than 5-FU

Jennifer Bré, Alison L. Dickson, Oliver J. Read, Ying Zhang, Clarissa M. Czekster, David J. Harrison

Cancer Res (2022) 82 (12_Supplement): 1835.

DOI: https://doi.org/10.1158/1538-7445.AM2022-1835

Published: 15 June 2022

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Journal Articles

Abstract 1003: NUC-1031 causes incorporation of fluorinated deoxycytidine into DNA, inducing persistent damage in biliary tract cancer cells

Dillum Patel, Alison L. Dickson, Oliver J. Read, Clarissa M. Czekster, Essam A. Ghazaly, David J. Harrison, Jennifer Bré

Cancer Res (2021) 81 (13_Supplement): 1003.

DOI: https://doi.org/10.1158/1538-7445.AM2021-1003

Published: 01 July 2021

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Journal Articles

Abstract LB-368: Applications of automated image analysis, machine learning and spatial statistics for the improvement of stage II colorectal cancer prognosis

Ines P. Nearchou, Daniel A. Soutar, Kate Lillard, Ueno Hideki, Ognjen Arandjelović, David J. Harrison, Peter D. Caie

Cancer Res (2020) 80 (16_Supplement): LB-368.

DOI: https://doi.org/10.1158/1538-7445.AM2020-LB-368

Published: 15 August 2020

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Journal Articles

Abstract 2670: Combining automated image analysis and digital spatial profiling to investigate prognostic immune signatures in clear cell renal cell carcinoma

Raffaele De Filippis, Sarah Warren, Youngmi Kim, Andrew White, Jason Reeves, Grant D. Stewart, David J. Harrison, Joe M. Beechem, Peter D. Caie

Cancer Res (2020) 80 (16_Supplement): 2670.

DOI: https://doi.org/10.1158/1538-7445.AM2020-2670

Published: 15 August 2020

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Journal Articles

Abstract 1848: NUC-3373 induces ER stress and the release of damage associated molecular patterns in colorectal cancer cells

Fiona G. McKissock, Oliver J. Read, David J. Harrison

Cancer Res (2020) 80 (16_Supplement): 1848.

DOI: https://doi.org/10.1158/1538-7445.AM2020-1848

Published: 15 August 2020

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Journal Articles

Abstract 1840: NUC-1031 causes release of DAMPs and upregulates PD-L1 expression in lung cancer cells

Jennifer Bré, Oliver J. Read, David J. Harrison

Cancer Res (2020) 80 (16_Supplement): 1840.

DOI: https://doi.org/10.1158/1538-7445.AM2020-1840

Published: 15 August 2020

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Journal Articles

Abstract 2082: NUC 3373 induces a cytoplasmic translocation of thymidylate synthase in colorectal carcinoma cell lines

Fiona G. McKissock, In Hwa Um, Peter Mullen, David J. Harrison

Cancer Res (2019) 79 (13_Supplement): 2082.

DOI: https://doi.org/10.1158/1538-7445.AM2019-2082

Published: 01 July 2019

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Journal Articles

Abstract 4440: Genetic knockdown of the E3 ubiquitin ligase Itch increases pancreatic cell line sensitivity to cancer therapeutics: A comparison between different gene editing techniques

Oliver J. Read, David J. Harrison, Paul A. Reynolds

Cancer Res (2019) 79 (13_Supplement): 4440.

DOI: https://doi.org/10.1158/1538-7445.AM2019-4440

Published: 01 July 2019

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Journal Articles

Abstract 2081: NUC 3373 induces endoplasmic reticulum stress in colorectal cancer cells

Fiona G. McKissock, Asmithaa Prabhakaran, Peter Mullen, David J. Harrison

Cancer Res (2019) 79 (13_Supplement): 2081.

DOI: https://doi.org/10.1158/1538-7445.AM2019-2081

Published: 01 July 2019

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Journal Articles

Abstract 1855: NUC-1031 overcomes resistance associated with gemcitabine in cancer patients

Jennifer Bré, Awa Sarr, Peter Mullen, In Hwa Um, Sarah P. Blagden, Paul A. Reynolds, David J. Harrison

Cancer Res (2018) 78 (13_Supplement): 1855.

DOI: https://doi.org/10.1158/1538-7445.AM2018-1855

Published: 01 July 2018

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Journal Articles

Abstract 572: Genome-scale CRISPR/Cas9 screen identifies factors required for sensitivity to pyrimidine nucleoside analogs

Awa SARR, Jennifer Bré, Peter Mullen, Sarah Blagden, In Hwa Um, David J. Harrison, Paul A. Reynolds

Cancer Res (2018) 78 (13_Supplement): 572.

DOI: https://doi.org/10.1158/1538-7445.AM2018-572

Published: 01 July 2018

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Journal Articles

Abstract P6-02-08: Novel flavonoid Anto-028 shows promising antitumor activity in preclinical models of breast cancer

Carlos Martinez-Perez, Carol Ward, Peter Mullen, Graeme Cook, Donald McPhail, Arran K Turnbull, David J Harrison, Simon P Langdon

Cancer Res (2015) 75 (9_Supplement): P6-02-08.

DOI: https://doi.org/10.1158/1538-7445.SABCS14-P6-02-08

Published: 01 May 2015

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Journal Articles

Abstract 4085: The roles of HDACs in chromatin remodelling and response to chemotherapy in cancer

Rui Huang, Simon P. Langdon, David J. Harrison, Dana Faratian

Cancer Res (2012) 72 (8_Supplement): 4085.

DOI: https://doi.org/10.1158/1538-7445.AM2012-4085

Published: 15 April 2012

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Journal Articles

Abstract 3642: Phospho-CHK1 as a prognostic biomarker in ovarian cancer and a potential target in platinum-resistant disease

Kyle E. Francis, Dana Faratian, Charlene Kay, Peter Mullen, Simon P. Langdon, David J. Harrison

Cancer Res (2012) 72 (8_Supplement): 3642.

DOI: https://doi.org/10.1158/1538-7445.AM2012-3642

Published: 15 April 2012

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Journal Articles

Abstract 885: Integrated analysis of colorectal cancer cell lines reveals an amplicon driver which may be involved in platinium resistance

Romina Briffa, David J. Harrison, Dana Faratian

Cancer Res (2012) 72 (8_Supplement): 885.

DOI: https://doi.org/10.1158/1538-7445.AM2012-885

Published: 15 April 2012

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Journal Articles

Tyrosine Phosphorylation Profiling Reveals the Signaling Network Characteristics of Basal Breast Cancer Cells

Cancer Res (2010) 70 (22): 9391–9401.

DOI: https://doi.org/10.1158/0008-5472.CAN-10-0911

Published: 14 November 2010

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Includes: Supplementary data

Journal Articles

Systems Biology Reveals New Strategies for Personalizing Cancer Medicine and Confirms the Role of PTEN in Resistance to Trastuzumab

Dana Faratian, Alexey Goltsov, Galina Lebedeva, Anatoly Sorokin, Stuart Moodie, Peter Mullen, Charlene Kay, In Hwa Um, Simon Langdon, Igor Goryanin, David J. Harrison

Cancer Res (2009) 69 (16): 6713–6720.

DOI: https://doi.org/10.1158/0008-5472.CAN-09-0777

Published: 12 August 2009

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Includes: Supplementary data

Journal Articles

WWOX Gene Expression Abolishes Ovarian Cancer Tumorigenicity In vivo and Decreases Attachment to Fibronectin via Integrin α₃

Charlie Gourley, Adam J.W. Paige, Karen J. Taylor, Carol Ward, Barbara Kuske, Jieqing Zhang, Mingjun Sun, Szymon Janczar, David J. Harrison, Morwenna Muir, John F. Smyth, Hani Gabra

Cancer Res (2009) 69 (11): 4835–4842.

DOI: https://doi.org/10.1158/0008-5472.CAN-08-2974

Published: 01 June 2009

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Includes: Supplementary data

Journal Articles

1Mb resolution array-CGH identifies small chromosome aberrations in chromosome unstable and microsatellite unstable colorectal cancers

George Poulogiannis, Koichi Ichimura, Nigel G. A. Miller, John R. Apps, Ian M. Frayling, Robert G. Morris, David J. Harrison, Peter V. Collins, Andrew H. Wyllie, Mark J. Arends

Cancer Res (2005) 65 (9_Supplement): 381.

Published: 01 May 2005

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NARROW

Abstract 1113: NUC-3373 potentiates immune-mediated cytotoxicity of CRC cells

Abstract 1835: NUC-3373 targets the DNA-directed pathway more effectively than 5-FU

Abstract 1003: NUC-1031 causes incorporation of fluorinated deoxycytidine into DNA, inducing persistent damage in biliary tract cancer cells

Abstract LB-368: Applications of automated image analysis, machine learning and spatial statistics for the improvement of stage II colorectal cancer prognosis

Abstract 2670: Combining automated image analysis and digital spatial profiling to investigate prognostic immune signatures in clear cell renal cell carcinoma

Abstract 1848: NUC-3373 induces ER stress and the release of damage associated molecular patterns in colorectal cancer cells

Abstract 1840: NUC-1031 causes release of DAMPs and upregulates PD-L1 expression in lung cancer cells

Abstract 2082: NUC 3373 induces a cytoplasmic translocation of thymidylate synthase in colorectal carcinoma cell lines

Abstract 4440: Genetic knockdown of the E3 ubiquitin ligase Itch increases pancreatic cell line sensitivity to cancer therapeutics: A comparison between different gene editing techniques

Abstract 2081: NUC 3373 induces endoplasmic reticulum stress in colorectal cancer cells

Abstract 1855: NUC-1031 overcomes resistance associated with gemcitabine in cancer patients

Abstract 572: Genome-scale CRISPR/Cas9 screen identifies factors required for sensitivity to pyrimidine nucleoside analogs

Abstract P6-02-08: Novel flavonoid Anto-028 shows promising antitumor activity in preclinical models of breast cancer

Abstract 4085: The roles of HDACs in chromatin remodelling and response to chemotherapy in cancer

Abstract 3642: Phospho-CHK1 as a prognostic biomarker in ovarian cancer and a potential target in platinum-resistant disease

Abstract 885: Integrated analysis of colorectal cancer cell lines reveals an amplicon driver which may be involved in platinium resistance

Tyrosine Phosphorylation Profiling Reveals the Signaling Network Characteristics of Basal Breast Cancer Cells

Systems Biology Reveals New Strategies for Personalizing Cancer Medicine and Confirms the Role of PTEN in Resistance to Trastuzumab

WWOX Gene Expression Abolishes Ovarian Cancer Tumorigenicity In vivo and Decreases Attachment to Fibronectin via Integrin α₃

1Mb resolution array-CGH identifies small chromosome aberrations in chromosome unstable and microsatellite unstable colorectal cancers

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