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Journal Articles

Abstract LB133: EGFR upregulation in breast cancer cells: A key mechanism of escape from antiestrogen induced death, autophagy, and senescence

Mackenzie L. Hagan, Michael McGrath, Carol Joseph, Allison Lewis, John R. Barrett, Muthusamy Thangaraju, David Gewirtz, Patricia V. Schoenlein

Cancer Res (2022) 82 (12_Supplement): LB133.

https://doi.org/10.1158/1538-7445.AM2022-LB133

Published: 15 June 2022

View article titled, Abstract LB133: EGFR upregulation in breast cancer cells: A key mechanism of escape from antiestrogen induced death, autophagy, and senescence

Journal Articles

Abstract 2024: Studying the effects of interfering with doxorubicin-induced senescence in human colon cancer HCT116 cells

Moureq Rashed Alotaibi, Homood As Sobeia, Munirah Alohaydib, Faten Alaqil, Khalid Alhazzani, Ali Alhoshani, Tareq Saleh, David Gewirtz

Cancer Res (2021) 81 (13_Supplement): 2024.

https://doi.org/10.1158/1538-7445.AM2021-2024

Published: 01 July 2021

View article titled, Abstract 2024: Studying the effects of interfering with doxorubicin-induced senescence in human colon cancer HCT116 cells

Journal Articles

Abstract 5831: Clearance of therapy-induced senescent cancer cells by the senolytic ABT-263 in a model of non-small cell lung cancer

Valerie Carpenter, Tareq Saleh, David Gewirtz

Cancer Res (2020) 80 (16_Supplement): 5831.

https://doi.org/10.1158/1538-7445.AM2020-5831

Published: 15 August 2020

View article titled, Abstract 5831: Clearance of therapy-induced senescent cancer cells by the senolytic ABT-263 in a model of non-small cell lung cancer

Journal Articles

Abstract 1330: Role of epigenetic remodeling in sensitizing triple-negative breast cancer cells to treatment through enhanced chemotherapy-induced autophagy

Liliya Tyutyunyk, Joseph Landry, David Gewirtz, Nga Dao

Cancer Res (2018) 78 (13_Supplement): 1330.

https://doi.org/10.1158/1538-7445.AM2018-1330

Published: 01 July 2018

View article titled, Abstract 1330: Role of epigenetic remodeling in sensitizing triple-negative breast cancer cells to treatment through enhanced chemotherapy-induced autophagy

Journal Articles

Abstract 1326: Nonprotective autophagy fails to confer resistance to radiation

Jingwen Xu, Emmanuel Kenneth Cudjoe, Tareq Saleh, Nipa Patel, Moureq Alotaibi, Yingliang Wu, Santiago Lima, David Gewirtz

Cancer Res (2018) 78 (13_Supplement): 1326.

https://doi.org/10.1158/1538-7445.AM2018-1326

Published: 01 July 2018

View article titled, Abstract 1326: Nonprotective autophagy fails to confer resistance to radiation

Journal Articles

Abstract 1323: A p53-dependent switch between cytoprotective and nonprotective autophagy influences tumor cell sensitivity to cisplatin

Jingwen Xu, Tareq Saleh, Nipa Patel, Yingliang Wu, Santiago Lima, David Gewirtz

Cancer Res (2018) 78 (13_Supplement): 1323.

https://doi.org/10.1158/1538-7445.AM2018-1323

Published: 01 July 2018

View article titled, Abstract 1323: A p53-dependent switch between cytoprotective and nonprotective autophagy influences tumor cell sensitivity to cisplatin

Journal Articles

Abstract 460: Reversibility of chemotherapy-induced senescence in breast tumor cells in culture and in vivo

Liliya Tyutyunyk, Joseph Landry, Tareq Saleh, David Gewirtz

Cancer Res (2018) 78 (13_Supplement): 460.

https://doi.org/10.1158/1538-7445.AM2018-460

Published: 01 July 2018

View article titled, Abstract 460: Reversibility of chemotherapy-induced senescence in breast tumor cells in culture and in vivo

Journal Articles

Abstract 3314: Synergistic effects of chemotherapy-induced autophagy and epigenetic remodeling

Liliya Tyutyunyk, Joseph Landry, Tareq Saleh, David Gewirtz

Cancer Res (2017) 77 (13_Supplement): 3314.

https://doi.org/10.1158/1538-7445.AM2017-3314

Published: 01 July 2017

View article titled, Abstract 3314: Synergistic effects of chemotherapy-induced autophagy and epigenetic remodeling

Journal Articles

Abstract 2848: Autophagy, senescence and proliferative recovery subsequent to DNA damage in radiation sensitization by PARP inhibition

Moureq R. Alotaibi, Khushboo Sharma, Tareq Saleh, Lawrence Povirk, Eric Hendrickson, David Gewirtz

Cancer Res (2016) 76 (14_Supplement): 2848.

https://doi.org/10.1158/1538-7445.AM2016-2848

Published: 15 July 2016

View article titled, Abstract 2848: Autophagy, senescence and proliferative recovery subsequent to DNA damage in radiation sensitization by PARP inhibition

Journal Articles

Abstract 3528: Induction of cytoprotective autophagy and senescence in response to chemotherapy and ionizing-radiation as possible mechanisms of tumor dormancy

Theresa Thekkudan, Supriya Joshi, David Gewirtz

Cancer Res (2016) 76 (14_Supplement): 3528.

https://doi.org/10.1158/1538-7445.AM2016-3528

Published: 15 July 2016

View article titled, Abstract 3528: Induction of cytoprotective autophagy and senescence in response to chemotherapy and ionizing-radiation as possible mechanisms of tumor dormancy

Journal Articles

Abstract 3539: Vitamin D/EB 1089 mediated radio-sensitization of lung cancer cells and head and neck cancer cells

Theresa Thekkudan, Khushboo Sharma, Tareq Saleh, David Gewirtz

Cancer Res (2016) 76 (14_Supplement): 3539.

https://doi.org/10.1158/1538-7445.AM2016-3539

Published: 15 July 2016

View article titled, Abstract 3539: Vitamin D/EB 1089 mediated radio-sensitization of lung cancer cells and head and neck cancer cells

Journal Articles

Abstract 1013: Understanding the molecular pathways underlying radio-sensitization of non-small cell lung cancer (NSCLC) by vitamin D (EB1089)

Khushboo Sharma, Theresa Thekkudan, David Gewirtz, Hisashi Harada, Frank Torti, Suzy Torti

Cancer Res (2015) 75 (15_Supplement): 1013.

https://doi.org/10.1158/1538-7445.AM2015-1013

Published: 01 August 2015

View article titled, Abstract 1013: Understanding the molecular pathways underlying radio-sensitization of non-small cell lung cancer (NSCLC) by vitamin D (EB1089)

Journal Articles

Abstract 998: Induction of non-protective autophagy by radiation in tumor cells: Implications for autophagy inhibition as a therapeutic strategy

Shweta Chakradeo, Khushboo Sharma, Aisha Alhaddad, Duaa Bakhshwin, Ngoc Le, Hisashi Harada, W. Andrew Yeudall, Suzy Torti, Frank Torti, David Gewirtz

Cancer Res (2015) 75 (15_Supplement): 998.

https://doi.org/10.1158/1538-7445.AM2015-998

Published: 01 August 2015

View article titled, Abstract 998: Induction of non-protective autophagy by radiation in tumor cells: Implications for autophagy inhibition as a therapeutic strategy

Journal Articles

Abstract 1329: Sensitization of non-small cell lung cancer cells (NSCLC) to radiation by Vitamin D (EB 1089)

Khushboo Sharma, David Gewirtz

Cancer Res (2014) 74 (19_Supplement): 1329.

https://doi.org/10.1158/1538-7445.AM2014-1329

Published: 01 October 2014

View article titled, Abstract 1329: Sensitization of non-small cell lung cancer cells (NSCLC) to radiation by Vitamin D (EB 1089)

Journal Articles

Abstract 1400: Mitigation of radiation-induced injury with the nitric oxide synthase co-factor, tetrahydrobiopterin

Jing Wang, Peck-Sun Lin, Ross B. Mikkelsen, David Gewirtz, Mitchell S. Anscher, Paul R. Graves

Cancer Res (2010) 70 (8_Supplement): 1400.

https://doi.org/10.1158/1538-7445.AM10-1400

Published: 15 April 2010

View article titled, Abstract 1400: Mitigation of radiation-induced injury with the nitric oxide synthase co-factor, tetrahydrobiopterin

Journal Articles

Abstract #870: Autophagic cell death induced by a novel microtubule poison in HCT-116 colon carcinoma cells

Tuyen Nguyen, John Gupton, Jonathan Biggers, Glen Kellogg, Scott Henderson, David Gewirtz

Cancer Res (2009) 69 (9_Supplement): 870.

Published: 01 May 2009

View article titled, Abstract #870: Autophagic cell death induced by a novel microtubule poison in HCT-116 colon carcinoma cells

Journal Articles

Abstract #869: Potentiation of the response to ionizing radiation in breast tumor cells by the vitamin D3 analog, EB 1089

Molly Hilliker, David Gewirtz

Cancer Res (2009) 69 (9_Supplement): 869.

Published: 01 May 2009

View article titled, Abstract #869: Potentiation of the response to ionizing radiation in breast tumor cells by the vitamin D3 analog, EB 1089

Journal Articles

Abstract #1702: Molecular basis for the accelerated senescence response to doxorubicin in p53 wild-type and p53 null/mutant breast tumor cells.

Xu Di, David Gewirtz

Cancer Res (2009) 69 (9_Supplement): 1702.

Published: 01 May 2009

View article titled, Abstract #1702: Molecular basis for the accelerated senescence response to doxorubicin in p53 wild-type and p53 null/mutant breast tumor cells.

Journal Articles

Promotion of DNA strand breaks, interstrand cross links and apoptotic cell death in A2780 human ovarian cancer cells by transplatinum planar amine complexes.

Sheena Aris, David Gewirtz, John Ryan, Nicholas Farrell

Cancer Res (2007) 67 (9_Supplement): 3207.

Published: 01 May 2007

View article titled, Promotion of DNA strand breaks, interstrand cross links and apoptotic cell death in A2780 human ovarian cancer cells by transplatinum planar amine complexes.

Journal Articles

Autophagic cell death induced by a novel class of substituted pyrroles in the breast tumor cell

Christopher Arthur, Xu Di, John Gupton, Andrew Yeudall, Glen Kellogg, Myles cabot, David Gewirtz

Cancer Res (2007) 67 (9_Supplement): 1463.

Published: 01 May 2007

View article titled, Autophagic cell death induced by a novel class of substituted pyrroles in the breast tumor cell

NARROW

Abstract LB133: EGFR upregulation in breast cancer cells: A key mechanism of escape from antiestrogen induced death, autophagy, and senescence

Abstract 2024: Studying the effects of interfering with doxorubicin-induced senescence in human colon cancer HCT116 cells

Abstract 5831: Clearance of therapy-induced senescent cancer cells by the senolytic ABT-263 in a model of non-small cell lung cancer

Abstract 1330: Role of epigenetic remodeling in sensitizing triple-negative breast cancer cells to treatment through enhanced chemotherapy-induced autophagy

Abstract 1326: Nonprotective autophagy fails to confer resistance to radiation

Abstract 1323: A p53-dependent switch between cytoprotective and nonprotective autophagy influences tumor cell sensitivity to cisplatin

Abstract 460: Reversibility of chemotherapy-induced senescence in breast tumor cells in culture and in vivo

Abstract 3314: Synergistic effects of chemotherapy-induced autophagy and epigenetic remodeling

Abstract 2848: Autophagy, senescence and proliferative recovery subsequent to DNA damage in radiation sensitization by PARP inhibition

Abstract 3528: Induction of cytoprotective autophagy and senescence in response to chemotherapy and ionizing-radiation as possible mechanisms of tumor dormancy

Abstract 3539: Vitamin D/EB 1089 mediated radio-sensitization of lung cancer cells and head and neck cancer cells

Abstract 1013: Understanding the molecular pathways underlying radio-sensitization of non-small cell lung cancer (NSCLC) by vitamin D (EB1089)

Abstract 998: Induction of non-protective autophagy by radiation in tumor cells: Implications for autophagy inhibition as a therapeutic strategy

Abstract 1329: Sensitization of non-small cell lung cancer cells (NSCLC) to radiation by Vitamin D (EB 1089)

Abstract 1400: Mitigation of radiation-induced injury with the nitric oxide synthase co-factor, tetrahydrobiopterin

Abstract #870: Autophagic cell death induced by a novel microtubule poison in HCT-116 colon carcinoma cells

Abstract #869: Potentiation of the response to ionizing radiation in breast tumor cells by the vitamin D3 analog, EB 1089

Abstract #1702: Molecular basis for the accelerated senescence response to doxorubicin in p53 wild-type and p53 null/mutant breast tumor cells.

Promotion of DNA strand breaks, interstrand cross links and apoptotic cell death in A2780 human ovarian cancer cells by transplatinum planar amine complexes.

Autophagic cell death induced by a novel class of substituted pyrroles in the breast tumor cell

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