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David G. Mutch
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Journal Articles

Abstract B094: A combined RAD51 and phosphorylated replication protein assay predict response to platinum chemotherapy in high-grade serous ovarian cancer

Free
Amanda J. Compadre, Carmen Sandoval, Olivia Graham, Jeimmy Rodriguez, Lindsay M. Kuroki, Carolyn K. McCourt, Andrea Hagemann, Premal H. Thaker, L. Stewart Massad, Matthew A. Powell, David G. Mutch, Ian Hagemann, Katherine Fuh, Lulu Sun, Peinan Zhao, Dineo Khabele, Priyanka Verma, Elena Lomonosova, Mary M. Mullen
Journal: Cancer Research
Cancer Res (2024) 84 (5_Supplement_2): B094.
https://doi.org/10.1158/1538-7445.OVARIAN23-B094
Published: 04 March 2024
View articletitled, Abstract B094: A combined RAD51 and phosphorylated replication protein assay predict response to platinum chemotherapy in high-grade serous ovarian cancer
Journal Articles

Abstract LB081: GAS6-AXL inhibition by AVB-500 overcomes resistance to paclitaxel in endometrial cancer by decreasing tumor cell glycolysis

Free
Shaina F. Bruce, Kevin Cho, Hollie Noia, Elena Lomonosova, Elizabeth Stock, Alyssa Oplt, Barbara Blachut, Mary M. Mullen, Lindsay M. Kuroki, Andrea R. Hagemann, Carolyn K. McCourt, Premal H. Thaker, Dineo Khabele, Matthew A. Powell, David G. Mutch, Leah P. Shriver, Gary J. Patti, Katherine C. Fuh
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): LB081.
https://doi.org/10.1158/1538-7445.AM2022-LB081
Published: 15 June 2022
View articletitled, Abstract LB081: GAS6-AXL inhibition by AVB-500 overcomes resistance to paclitaxel in endometrial cancer by decreasing tumor cell glycolysis
Journal Articles

Abstract 2429: Tumor and stromal AXL expression regulate ovarian cancer metastasis

Free
Mary Margaret Mullen, Lillian N. van Biljon, Jeanne Quinn, Molly Greenwade, Gregory Opara, Hollie Noia, Ian S. Hagemann, Andrea R. Hagemann, Lindsay M. Kuroki, Carolyn K. McCourt, Premal H. Thaker, Matthew A. Powell, David G. Mutch, Dineo Khabele, Katherine C. Fuh
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2429.
https://doi.org/10.1158/1538-7445.AM2022-2429
Published: 15 June 2022
View articletitled, Abstract 2429: Tumor and stromal AXL expression regulate ovarian cancer metastasis
Journal Articles

Abstract 2202: Genetic characterization of metastasis and prognosis in high-grade serous ovarian cancer

Free
Emilee N. Kotnik, Nicholas C. Spies, Tiandao Li, Matthew Inkman, Jin Zhang, Fernanda Martins-Rodrigues, Ian S. Hagemann, Carolyn K. McCourt, Premal H. Thaker, Andrea R. Hagemann, Matthew A. Powell, David G. Mutch, Christopher A. Maher, Christopher A. Miller, Katherine C. Fuh
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2202.
https://doi.org/10.1158/1538-7445.AM2021-2202
Published: 01 July 2021
View articletitled, Abstract 2202: Genetic characterization of metastasis and prognosis in high-grade serous ovarian cancer
Journal Articles

Dicer1 Phosphomimetic Promotes Tumor Progression and Dissemination

Free
Neeraj K. Aryal, Vinod Pant, Amanda R. Wasylishen, Bobbie J. Rimel, Laura Baseler, Adel K. El-Naggar, David G. Mutch, Paul J. Goodfellow, Swathi Arur, Guillermina Lozano
Journal: Cancer Research
Cancer Res (2019) 79 (10): 2662–2668.
https://doi.org/10.1158/0008-5472.CAN-18-2460
Published: 15 May 2019
View articletitled, Dicer1 Phosphomimetic Promotes Tumor Progression and Dissemination
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Includes: Supplementary data
Journal Articles

Adipokines Deregulate Cellular Communication via Epigenetic Repression of Gap Junction Loci in Obese Endometrial Cancer

Free
Srikanth R. Polusani, Yi-Wen Huang, Guangcun Huang, Chun-Wei Chen, Chiou-Miin Wang, Li-Ling Lin, Pawel Osmulski, Nicholas D. Lucio, Lu Liu, Ya-Ting Hsu, Yufan Zhou, Chun-Lin Lin, Irene Aguilera-Barrantes, Philip T. Valente, Edward R. Kost, Chun-Liang Chen, Eun Yong Shim, Sang Eun Lee, Jianhua Ruan, Maria E. Gaczynska, Pearlly Yan, Paul J. Goodfellow, David G. Mutch, Victor X. Jin, Bruce J. Nicholson, Tim H.-M. Huang, Nameer B. Kirma
Journal: Cancer Research
Cancer Res (2019) 79 (1): 196–208.
https://doi.org/10.1158/0008-5472.CAN-18-1615
Published: 02 January 2019
View articletitled, Adipokines Deregulate Cellular Communication via Epigenetic Repression of Gap Junction Loci in Obese Endometrial Cancer
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Includes: Supplementary data
Journal Articles

Abstract 2002: MAX mutations in endometrial cancer are associated with poor patient outcome, altered E-box binding, and increased tumor vascularity

Free
Christopher J. Walker, Craig Rush, Paola Dama, Maggie Stein, Reena Shakya, Matthew O’Hern, David G. Mutch, David E. Cohn, Paul J. Goodfellow
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2002.
https://doi.org/10.1158/1538-7445.AM2016-2002
Published: 15 July 2016
View articletitled, Abstract 2002: MAX mutations in endometrial cancer are associated with poor patient outcome, altered E-box binding, and increased tumor vascularity
Journal Articles

Abstract 5300: Loss of function of two closely linked tumor suppressors contributes to biologic aggressiveness in endometrial cancers: Co-mutation of CTCF and ZFHX3

Free
Christopher J. Walker, Mario A. Miranda, Matthew O'Hern, Kevin Coombes, Ralf Bundschuh, David G. Mutch, Paul J. Goodfellow
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5300.
https://doi.org/10.1158/1538-7445.AM2015-5300
Published: 01 August 2015
View articletitled, Abstract 5300: Loss of function of two closely linked tumor suppressors contributes to biologic aggressiveness in endometrial cancers: Co-mutation of CTCF and ZFHX3
Journal Articles

Abstract 1376: EpCAM-mediated hypomethylation of BMP and cell adhesion genes is associated with advanced endometrial cancer

Free
Ya-Ting Hsu, Fei Gu, Yi-Wen Huang, Joseph Liu, Jianhua Ruan, Rui-Lan Huang, Chiou-Miin Wang, Chun-Liang Chen, Rohit R. Jadhav, Yao Wang, Victor X. Jin, Hung-Cheng Lai, David G. Mutch, Paul J. Goodfellow, Ian M. Thompson, Nameer B. Kirma, Tim H.M. Huang
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1376.
https://doi.org/10.1158/1538-7445.AM2014-1376
Published: 01 October 2014
View articletitled, Abstract 1376: EpCAM-mediated hypomethylation of BMP and cell adhesion genes is associated with advanced endometrial cancer
Journal Articles

Abstract 1540: CCCTC-binding factor (CTCF) mutation in endometrioid endometrial carcinoma (EEC): Master epimutator contributing to biologic aggressiveness

Free
Christopher J. Walker, Mario A. Miranda, David G. Mutch, Paul Goodfellow
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1540.
https://doi.org/10.1158/1538-7445.AM2014-1540
Published: 01 October 2014
View articletitled, Abstract 1540: CCCTC-binding factor (CTCF) mutation in endometrioid endometrial carcinoma (EEC): Master epimutator contributing to biologic aggressiveness
Journal Articles

Abstract 1378: Factors influencing survival in gynecologic oncology patients diagnosed with intestinal perforation and pneumatosis intestinalis.

Free
Gunjal Garg, Shabnam Pourbolghasem, Gongfu Zhou, Matthew A. Powell, Premal H. Thaker, Andrea R. Hagemann, Ivy Wilkinson-Ryan, L. Stewart Massad, David G. Mutch
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1378.
https://doi.org/10.1158/1538-7445.AM2013-1378
Published: 15 April 2013
View articletitled, Abstract 1378: Factors influencing survival in gynecologic oncology patients diagnosed with intestinal perforation and pneumatosis intestinalis.
Journal Articles

Abstract 169: Temporal trends, predictors, and outcome of chemotherapy in elderly women with advanced stage endometrial cancer.

Free
Gunjal Garg, Zainab Siddiq, Gongfu Zhou, Matthew A. Powell, Thomas Herzog, David G. Mutch, Jason D. Wright
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 169.
https://doi.org/10.1158/1538-7445.AM2013-169
Published: 15 April 2013
View articletitled, Abstract 169: Temporal trends, predictors, and outcome of chemotherapy in elderly women with advanced stage endometrial cancer.
Journal Articles

Epigenetic Repression of microRNA-129-2 Leads to Overexpression of SOX4 Oncogene in Endometrial Cancer

Free
Yi-Wen Huang, Joseph C. Liu, Daniel E. Deatherage, Jingqin Luo, David G. Mutch, Paul J. Goodfellow, David S. Miller, Tim H-M. Huang
Journal: Cancer Research
Cancer Res (2009) 69 (23): 9038–9046.
https://doi.org/10.1158/0008-5472.CAN-09-1499
Published: 30 November 2009
View articletitled, Epigenetic Repression of microRNA-129-2 Leads to Overexpression of SOX4 Oncogene in Endometrial Cancer
Open the PDF for Epigenetic Repression of microRNA-129-2 Leads to Overexpression of SOX4 Oncogene in Endometrial Cancer in another window
Includes: Supplementary data
Journal Articles

Hypermethylation of CIDEA and RXFP3 as potential epigenetic markers for endometrial cancer

Free
Yi-Wen Huang, Daniel Deatherage, Pearlly Yan, Mary Ann Mallon, David Miller, David G Mutch, Paul Goodfellow, Tim Huang
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 50.
Published: 01 May 2008
View articletitled, Hypermethylation of CIDEA and RXFP3 as potential epigenetic markers for endometrial cancer
Journal Articles

CD83 Gene Polymorphisms Increase Susceptibility to Human Invasive Cervical Cancer

Free
Zhengyan Zhang, Ingrid Borecki, Loan Nguyen, Duanduan Ma, Kimberly Smith, Phyllis C. Huettner, David G. Mutch, Thomas J. Herzog, Randall K. Gibb, Matthew A. Powell, Perry W. Grigsby, L. Stewart Massad, Enrique Hernandez, Patricia L. Judson, Elizabeth M. Swisher, Sara Crowder, Jianduan Li, Daniela S. Gerhard, Janet S. Rader
Journal: Cancer Research
Cancer Res (2007) 67 (23): 11202–11208.
https://doi.org/10.1158/0008-5472.CAN-07-2677
Published: 03 December 2007
View articletitled, CD83 Gene Polymorphisms Increase Susceptibility to Human Invasive Cervical Cancer
Open the PDF for CD83 Gene Polymorphisms Increase Susceptibility to Human Invasive Cervical Cancer in another window
Journal Articles

MLH3 Mutation in Endometrial Cancer

Free
Nicholas P. Taylor, Matthew A. Powell, Randall K. Gibb, Janet S. Rader, Phyllis C. Huettner, Stephen N. Thibodeau, David G. Mutch, Paul J. Goodfellow
Journal: Cancer Research
Cancer Res (2006) 66 (15): 7502–7508.
https://doi.org/10.1158/0008-5472.CAN-06-0248
Published: 02 August 2006
View articletitled, MLH3 Mutation in Endometrial Cancer
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Journal Articles

Identification of cis genetic factors associated with aberrant MLH1 methylation in endometrial cancer

Free
Huiping Chen, Nicholas P. Taylor, Amy Liu, David G. Mutch, Paul J. Goodfellow
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 643–644.
Published: 01 May 2005
View articletitled, Identification of cis genetic factors associated with aberrant MLH1 methylation in endometrial cancer
Journal Articles

Allelic Loss of Sequences from the Long Arm of Chromosome 10 and Replication Errors in Endometrical Cancers

Free
Stacia L. Peiffer, Thomas J. Herzog, Doris J. Tribune, David G. Mutch, Deborah J. Gersell, Paul J. Goodfellow
Journal: Cancer Research
Cancer Res (1995) 55 (9): 1922–1926.
Published: 01 May 1995
View articletitled, Allelic Loss of Sequences from the Long Arm of Chromosome 10 and Replication Errors in Endometrical Cancers
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Journal Articles

Resistance to Cytolysis by Tumor Necrosis Factor α in Malignant Gynecological Cell Lines Is Associated with the Expression of Protein(s) That Prevent the Activation of Phospholipase A2 by Tumor Necrosis Factor α

Free
David G. Mutch, C. Bethan Powell, Ming-Shian Kao, John Leslie Collins
Journal: Cancer Research
Cancer Res (1992) 52 (4): 866–872.
Published: 01 February 1992
View articletitled, Resistance to Cytolysis by Tumor Necrosis Factor α in Malignant Gynecological Cell Lines Is Associated with the Expression of Protein(s) That Prevent the Activation of Phospholipase A2 by Tumor Necrosis Factor α
Open the PDF for Resistance to Cytolysis by Tumor Necrosis Factor α in Malignant Gynecological Cell Lines Is Associated with the Expression of Protein(s) That Prevent the Activation of Phospholipase A2 by Tumor Necrosis Factor α in another window
Journal Articles

Expression of a Resistance Mechanism in Ovarian and Cervical Carcinoma Cells Prevents Their Lysis by γ-Interferon

Free
L. Stewart Massad, David G. Mutch, C. Bethan Powell, Ming-Shian Kao, John Leslie Collins
Journal: Cancer Research
Cancer Res (1990) 50 (16): 4923–4928.
Published: 01 August 1990
View articletitled, Expression of a Resistance Mechanism in Ovarian and Cervical Carcinoma Cells Prevents Their Lysis by γ-Interferon
Open the PDF for Expression of a Resistance Mechanism in Ovarian and Cervical Carcinoma Cells Prevents Their Lysis by γ-Interferon in another window