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David D. Roberts
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Journal Articles

Abstract LB-213: Thrombospondin-1 regulates intestinal microbiota and bile acid metabolism in a murine model of colorectal cancer

David R. Soto-Pantoja, John M. Sipes, Brian Westwood, Nicole Morris, Nancy J. Emenaker, David D. Roberts
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-213.
https://doi.org/10.1158/1538-7445.AM2017-LB-213
Published: 01 July 2017
View article titled, Abstract LB-213: Thrombospondin-1 regulates intestinal microbiota and bile acid metabolism in a murine model of colorectal cancer
Journal Articles

Endoplasmic Reticulum Stress Protein GRP78 Modulates Lipid Metabolism to Control Drug Sensitivity and Antitumor Immunity in Breast Cancer

Katherine L. Cook, David R. Soto-Pantoja, Pamela A.G. Clarke, M. Idalia Cruz, Alan Zwart, Anni Wärri, Leena Hilakivi-Clarke, David D. Roberts, Robert Clarke
Journal: Cancer Research
Cancer Res (2016) 76 (19): 5657–5670.
https://doi.org/10.1158/0008-5472.CAN-15-2616
Published: 02 October 2016
View article titled, Endoplasmic Reticulum Stress Protein GRP78 Modulates Lipid Metabolism to Control Drug Sensitivity and Antitumor Immunity in Breast Cancer
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Includes: Supplementary data
Journal Articles

Abstract 1352: High-throughput matrix screening reveals synergistic chemotherapeutic combinations with blockade of CD47 to enhance cytotoxicity in breast cancer

David D. Roberts, Ashley Smith, John M. Sipes, Adam Wilson, Lesley Mathews-Griner, Rajarshi Guha, Craig J. Thomas, Marc Ferrer, David R. Soto-Pantoja
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1352.
https://doi.org/10.1158/1538-7445.AM2016-1352
Published: 15 July 2016
View article titled, Abstract 1352: High-throughput matrix screening reveals synergistic chemotherapeutic combinations with blockade of CD47 to enhance cytotoxicity in breast cancer
Journal Articles

Abstract 3054: CD47 signaling regulates a DNA damage response pathway by suppressing the expression of Schlafen-11 (SLFN11)

Anthony L. Schwartz, Sukhbir Kaur, Sai-Wen Tang, Yves Pommier, David D. Roberts
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3054.
https://doi.org/10.1158/1538-7445.AM2016-3054
Published: 15 July 2016
View article titled, Abstract 3054: CD47 signaling regulates a DNA damage response pathway by suppressing the expression of Schlafen-11 (SLFN11)
Journal Articles

Abstract 1202: Thrombospondin-1 regulates energy metabolism to increase carcinogenesis in an in vivo model of colorectal cancer

David R. Soto-Pantoja, John M. Sipes, Nicole Morris, Nancy J. Emmenaker, David D. Roberts
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1202.
https://doi.org/10.1158/1538-7445.AM2015-1202
Published: 01 August 2015
View article titled, Abstract 1202: Thrombospondin-1 regulates energy metabolism to increase carcinogenesis in an in vivo model of colorectal cancer
Journal Articles

NOS Inhibition Modulates Immune Polarization and Improves Radiation-Induced Tumor Growth Delay

Lisa A. Ridnour, Robert Y.S. Cheng, Jonathan M. Weiss, Sukhbir Kaur, David R. Soto-Pantoja, Debashree Basudhar, Julie L. Heinecke, C. Andrew Stewart, William DeGraff, Anastasia L. Sowers, Angela Thetford, Aparna H. Kesarwala, David D. Roberts, Howard A. Young, James B. Mitchell, Giorgio Trinchieri, Robert H. Wiltrout, David A. Wink
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (14): 2788–2799.
https://doi.org/10.1158/0008-5472.CAN-14-3011
Published: 14 July 2015
View article titled, NOS Inhibition Modulates Immune Polarization and Improves Radiation-Induced Tumor Growth Delay
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Includes: Supplementary data
Journal Articles

CD47 in the Tumor Microenvironment Limits Cooperation between Antitumor T-cell Immunity and Radiotherapy

David R. Soto-Pantoja, Masaki Terabe, Arunima Ghosh, Lisa A. Ridnour, William G. DeGraff, David A. Wink, Jay A. Berzofsky, David D. Roberts
Journal: Cancer Research
Cancer Res (2014) 74 (23): 6771–6783.
https://doi.org/10.1158/0008-5472.CAN-14-0037-T
Published: 30 November 2014
View article titled, CD47 in the Tumor Microenvironment Limits Cooperation between Antitumor T-cell Immunity and Radiotherapy
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Includes: Supplementary data
Journal Articles

Abstract 2434: Therapeutic targeting of CD47 regulates cell bioenergetics and autophagy to reduce breast tumor growth and protect against anthracycline-mediated cardiac toxicity

David R. Soto-Pantoja, John M. Sipes, Arunima Ghosh, Maria J. Merino, David D. Roberts
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2434.
https://doi.org/10.1158/1538-7445.AM2014-2434
Published: 01 October 2014
View article titled, Abstract 2434: Therapeutic targeting of CD47 regulates cell bioenergetics and autophagy to reduce breast tumor growth and protect against anthracycline-mediated cardiac toxicity
Journal Articles

Abstract 3451: Lack of CD47 in the tumor microenvironment enhances anti-tumor adaptive immune responses when combined with ionizing radiation

David R. Soto Pantoja, Terabe Masaki, Lisa A. Ridnour, William DeGraff, Jay A. Berzofsky, David D. Roberts
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3451.
https://doi.org/10.1158/1538-7445.AM2012-3451
Published: 15 April 2012
View article titled, Abstract 3451: Lack of CD47 in the tumor microenvironment enhances anti-tumor adaptive immune responses when combined with ionizing radiation
Journal Articles

Thrombospondin 1 Promotes Tumor Macrophage Recruitment and Enhances Tumor Cell Cytotoxicity of Differentiated U937 Cells

Gema Martin-Manso, Susana Galli, Lisa A. Ridnour, Maria Tsokos, David A. Wink, David D. Roberts
Journal: Cancer Research
Cancer Res (2008) 68 (17): 7090–7099.
https://doi.org/10.1158/0008-5472.CAN-08-0643
Published: 28 August 2008
View article titled, Thrombospondin 1 Promotes Tumor Macrophage Recruitment and Enhances Tumor Cell Cytotoxicity of Differentiated U937 Cells
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Journal Articles

Angiogenesis Inhibitors Target the Endothelial Cell Cytoskeleton through Altered Regulation of Heat Shock Protein 27 and Cofilin

Susan M. Keezer, Susan E. Ivie, Henry C. Krutzsch, Anita Tandle, Steven K. Libutti, David D. Roberts
Journal: Cancer Research
Cancer Res (2003) 63 (19): 6405–6412.
Published: 14 October 2003
View article titled, Angiogenesis Inhibitors Target the Endothelial Cell Cytoskeleton through Altered Regulation of Heat Shock Protein 27 and Cofilin
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Journal Articles

Identification of Heat Shock Protein 60 as a Molecular Mediator of α3β1 Integrin Activation

Heba O. Barazi, Longen Zhou, Nancy Smyth Templeton, Henry C. Krutzsch, David D. Roberts
Journal: Cancer Research
Cancer Res (2002) 62 (5): 1541–1548.
Published: 01 March 2002
View article titled, Identification of Heat Shock Protein 60 as a Molecular Mediator of α3β1 Integrin Activation
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Journal Articles

Thrombospondin-1 Promotes α3β1 Integrin-mediated Adhesion and Neurite-like Outgrowth and Inhibits Proliferation of Small Cell Lung Carcinoma Cells

Neng-hua Guo, Nancy Smyth Templeton, Hebah Al-Barazi, JoAnne Cashel, John M. Sipes, Henry C. Krutzsch, David D. Roberts
Journal: Cancer Research
Cancer Res (2000) 60 (2): 457–466.
Published: 01 January 2000
View article titled, Thrombospondin-1 Promotes α3β1 Integrin-mediated Adhesion and Neurite-like Outgrowth and Inhibits Proliferation of Small Cell Lung Carcinoma Cells
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Journal Articles

Differential Roles of Protein Kinase C and Pertussis Toxin-sensitive G-binding Proteins in Modulation of Melanoma Cell Proliferation and Motility by Thrombospondin 1

Neng-hua Guo, Vivian S. Zabrenetzky, Lakshmi Chandrasekaran, John M. Sipes, Jack Lawler, Henry C. Krutzsch, David D. Roberts
Journal: Cancer Research
Cancer Res (1998) 58 (14): 3154–3162.
Published: 01 July 1998
View article titled, Differential Roles of Protein Kinase C and Pertussis Toxin-sensitive G-binding Proteins in Modulation of Melanoma Cell Proliferation and Motility by Thrombospondin 1
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Journal Articles

Thrombospondin 1 and Type I Repeat Peptides of Thrombospondin 1 Specifically Induce Apoptosis of Endothelial Cells

Neng-hua Guo, Henry C. Krutzsch, John K. Inman, David D. Roberts
Journal: Cancer Research
Cancer Res (1997) 57 (9): 1735–1742.
Published: 01 May 1997
View article titled, Thrombospondin 1 and Type I Repeat Peptides of Thrombospondin 1 Specifically Induce Apoptosis of Endothelial Cells
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Journal Articles

Transfection of Thrombospondin 1 Complementary DNA into a Human Breast Carcinoma Cell Line Reduces Primary Tumor Growth, Metastatic Potential, and Angiogenesis

Debra L. Weinstat-Saslow, Vivian S. Zabrenetzky, Kenneth VanHoutte, William A. Frazier, David D. Roberts, Patricia S. Steeg
Journal: Cancer Research
Cancer Res (1994) 54 (24): 6504–6511.
Published: 01 December 1994
View article titled, Transfection of Thrombospondin 1 Complementary DNA into a Human Breast Carcinoma Cell Line Reduces Primary Tumor Growth, Metastatic Potential, and Angiogenesis
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Journal Articles

Suramin Inhibits Laminin- and Thrombospondin-mediated Melanoma Cell Adhesion and Migration and Binding of These Adhesive Proteins to Sulfatide

Vivian S. Zabrenetzky, Elise C. Kohn, David D. Roberts
Journal: Cancer Research
Cancer Res (1990) 50 (18): 5937–5942.
Published: 01 September 1990
View article titled, Suramin Inhibits Laminin- and Thrombospondin-mediated Melanoma Cell Adhesion and Migration and Binding of These Adhesive Proteins to Sulfatide
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Journal Articles

Interactions of Thrombospondin with Sulfated Glycolipids and Proteoglycans of Human Melanoma Cells

David D. Roberts
Journal: Cancer Research
Cancer Res (1988) 48 (23): 6785–6793.
Published: 01 December 1988
View article titled, Interactions of Thrombospondin with Sulfated Glycolipids and Proteoglycans of Human Melanoma Cells
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Journal Articles

Laminin-dependent and Laminin-independent Adhesion of Human Melanoma Cells to Sulfatides

David D. Roberts, Ulla M. Wewer, Lance A. Liotta, Victor Ginsburg
Journal: Cancer Research
Cancer Res (1988) 48 (12): 3367–3373.
Published: 01 June 1988
View article titled, Laminin-dependent and Laminin-independent Adhesion of Human Melanoma Cells to Sulfatides
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Journal Articles

Heterotopic Urinary Bladders in Rats Produced by an Isograft Inoculum of Bladder Fragments and Air

David D. Roberts, Joseph Leighton, Nabil A. Abaza, Walter Troll
Journal: Cancer Research
Cancer Res (1974) 34 (10): 2773–2778.
Published: 01 October 1974
View article titled, Heterotopic Urinary Bladders in Rats Produced by an Isograft Inoculum of Bladder Fragments and Air
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