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David D. Bowtell
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Journal Articles

Abstract IA001: Placing our bets to make a difference

David D. Bowtell
Journal: Cancer Research
Cancer Res (2024) 84 (5_Supplement_2): IA001.
https://doi.org/10.1158/1538-7445.OVARIAN23-IA001
Published: 04 March 2024
View article titled, Abstract IA001: Placing our bets to make a difference
Journal Articles

Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin

Gwo Yaw Ho, Elizabeth L. Kyran, Justin Bedo, Matthew J. Wakefield, Darren P. Ennis, Hasan B. Mirza, Cassandra J. Vandenberg, Elizabeth Lieschke, Andrew Farrell, Anthony Hadla, Ratana Lim, Genevieve Dall, James E. Vince, Ngee Kiat Chua, Olga Kondrashova, Rosanna Upstill-Goddard, Ulla-Maja Bailey, Suzanne Dowson, Patricia Roxburgh, Rosalind M. Glasspool, Gareth Bryson, Andrew V. Biankin, for the Scottish Genomes Partnership, Susanna L. Cooke, Gayanie Ratnayake, Orla McNally, Nadia Traficante, for the Australian Ovarian Cancer Study12,13, Anna DeFazio, S. John Weroha, David D. Bowtell, Iain A. McNeish, Anthony T. Papenfuss, Clare L. Scott, Holly E. Barker
Journal: Cancer Research
Cancer Res (2022) 82 (23): 4457–4473.
https://doi.org/10.1158/0008-5472.CAN-21-4012
Published: 02 December 2022
View article titled, Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin
Open the PDF for Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin in another window
Includes: Supplementary data
Journal Articles

Abstract 1074: Improving efficacy of microtubule inhibitors in the treatment of high-grade serous ovarian cancer and ovarian carcinosarcoma

Cassandra J. Vandenberg, Gwo-Yaw Ho, Ksenija Nesic, Elizabeth M. Swisher, Sean M. Grimmond, Matthew J. Wakefield, Holly E. Barker, David D. Bowtell, Clare L. Scott
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1074.
https://doi.org/10.1158/1538-7445.AM2021-1074
Published: 01 July 2021
View article titled, Abstract 1074: Improving efficacy of microtubule inhibitors in the treatment of high-grade serous ovarian cancer and ovarian carcinosarcoma
Journal Articles

Abstract 2722: The genomic landscape of high-grade serous ovarian cancer in long-term survivors

Dale W. Garsed, Ahwan Pandey, Sian Fereday, Kathryn Alsop, Maartje C. Wouters, Flurina Saner, Jessica A. Beach, Katy Milne, Catherine J. Kennedy, Joy Hendley, Nadia Traficante, Celeste L. Pearce, Malcolm C. Pike, Multidisciplinary Ovarian Cancer Outcomes Group, Susan J. Ramus, Martin Köbel, Brad H. Nelson, Ellen L. Goode, Anna deFazio, David D. Bowtell
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2722.
https://doi.org/10.1158/1538-7445.AM2019-2722
Published: 01 July 2019
View article titled, Abstract 2722: The genomic landscape of high-grade serous ovarian cancer in long-term survivors
Journal Articles

Abstract 3393: Characterizing recurrent high-grade serous ovarian cancer through whole-genome sequencing

Elizabeth L. Christie, Swetansu Pattnaik, Sian Fereday, Australian Ovarian Cancer Study, Heather Thorne, Andrea Bild, David D. Bowtell
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3393.
https://doi.org/10.1158/1538-7445.AM2018-3393
Published: 01 July 2018
View article titled, Abstract 3393: Characterizing recurrent high-grade serous ovarian cancer through whole-genome sequencing
Journal Articles

Abstract 218: The evolutionary history of 2,658 cancers

Clemency Jolly, Moritz Gerstung, Ignaty Leshchiner, Stefan C. Dentro, Santiago Gonzalez, Thomas J. Mitchell, Yulia Rubanova, Pavana Anur, Daniel Rosebrock, Kaixian Yu, Maxime Tarabichi, Amit Deshwar, Jeff Wintersinger, Kortine Kleinheinz, Ignacio Vásquez-García, Kerstin Haase, Subhajit Sengupta, Geoff Macintyre, Salem Malikic, Nilgun Donmez, Dimitri G. Livitz, Mark Cmero, Jonas Demeulemeester, Steve Schumacher, Yu Fan, Xiaotong Yao, Juhee Lee, Matthias Schlesner, Paul C. Boutros, David D. Bowtell, Hongtu Zhu, Gad Getz, Marcin Imielinski, Rameen Beroukhim, S Cenk Sahinalp, Yuan Ji, Martin Peifer, Florian Markowetz, Ville Mustonen, Ke Juan, Wenyi Wang, Quaid D. Morris, Paul T. Spellman, David C. Wedge, Peter Van Loo, PCAWG Evolution and Heterogeneity Working Group
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 218.
https://doi.org/10.1158/1538-7445.AM2018-218
Published: 01 July 2018
View article titled, Abstract 218: The evolutionary history of 2,658 cancers
Journal Articles

Genes Predisposed to DNA Hypermethylation during Acquired Resistance to Chemotherapy Are Identified in Ovarian Tumors by Bivalent Chromatin Domains at Initial Diagnosis

Edward Curry, Constanze Zeller, Nahal Masrour, Darren K. Patten, John Gallon, Charlotte S. Wilhelm-Benartzi, Sadaf Ghaem-Maghami, David D. Bowtell, Robert Brown
Journal: Cancer Research
Cancer Res (2018) 78 (6): 1383–1391.
https://doi.org/10.1158/0008-5472.CAN-17-1650
Published: 14 March 2018
View article titled, Genes Predisposed to DNA Hypermethylation during Acquired Resistance to Chemotherapy Are Identified in Ovarian Tumors by Bivalent Chromatin Domains at Initial Diagnosis
Open the PDF for Genes Predisposed to DNA Hypermethylation during Acquired Resistance to Chemotherapy Are Identified in Ovarian Tumors by Bivalent Chromatin Domains at Initial Diagnosis in another window
Includes: Supplementary data
Journal Articles

Abstract 2787: Identifying predictive markers of endocrine response in high-grade serous ovarian cancer using RNA sequencing

Cristina Mapagu, Sian Fereday, Australian Ovarian Cancer Study Group, David D. Bowtell, Paul R. Harnett, Anna deFazio
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2787.
https://doi.org/10.1158/1538-7445.AM2017-2787
Published: 01 July 2017
View article titled, Abstract 2787: Identifying predictive markers of endocrine response in high-grade serous ovarian cancer using RNA sequencing
Journal Articles

Abstract 3368: Omics data integration analysis in high grade serous ovarian cancer: results from three studies

Yanina Natanzon, Madalene Earp, Julie M. Cunningham, Kimberly R. Kalli, Stacey J. Winham, Sebastian M. Armasu, Melissa C. Larson, Chen Wang, David D. Bowtell, Dale W. Garsed, Ellen Goode
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3368.
https://doi.org/10.1158/1538-7445.AM2017-3368
Published: 01 July 2017
View article titled, Abstract 3368: <em>Omics</em> data integration analysis in high grade serous ovarian cancer: results from three studies
Journal Articles

Abstract 38: Using molecularly characterized patient-derived models to delineate underlying drivers and vulnerabilities of epithelial ovarian cancer

Monique D. Topp, Lynne Hartley, Michele Cook, Valerie Heong, Emma Boehm, Lauren McShane, Jan Pyman, Orla McNally, Sumi Ananda, Maria I. Harell, Dariush Etemadmoghadam, Laura Galletta, Kathryn Alsop, Gillian Mitchell, Stephen B. Fox, Jeff B. Kerr, Karla J. Hutt, Scott H. Kaufmann, Australian Ovarian Cancer Study (AOCS), Elizabeth M. Swisher, David D. Bowtell, Matthew M. Wakefield, Clare L. Scott
Journal: Cancer Research
Cancer Res (2014) 74 (23_Supplement): 38.
https://doi.org/10.1158/1538-7445.CANSUSC14-38
Published: 12 December 2014
View article titled, Abstract 38: Using molecularly characterized patient-derived models to delineate underlying drivers and vulnerabilities of epithelial ovarian cancer
Journal Articles

Primary Tumor Hypoxia Recruits CD11b+/Ly6Cmed/Ly6G+ Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche

Jaclyn Sceneay, Melvyn T. Chow, Anna Chen, Heloise M. Halse, Christina S.F. Wong, Daniel M. Andrews, Erica K. Sloan, Belinda S. Parker, David D. Bowtell, Mark J. Smyth, Andreas Möller
Journal: Cancer Research
Cancer Res (2012) 72 (16): 3906–3911.
https://doi.org/10.1158/0008-5472.CAN-11-3873
Published: 14 August 2012
View article titled, Primary Tumor Hypoxia Recruits CD11b<sup>+</sup>/Ly6C<sup>med</sup>/Ly6G<sup>+</sup> Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche
Open the PDF for Primary Tumor Hypoxia Recruits CD11b<sup>+</sup>/Ly6C<sup>med</sup>/Ly6G<sup>+</sup> Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche in another window
Includes: Supplementary data
Journal Articles

The Changing View of High-Grade Serous Ovarian Cancer

Els M.J.J. Berns, David D. Bowtell
Journal: Cancer Research
Cancer Res (2012) 72 (11): 2701–2704.
https://doi.org/10.1158/0008-5472.CAN-11-3911
Published: 31 May 2012
View article titled, The Changing View of High-Grade Serous Ovarian Cancer
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Journal Articles

Vascular Normalization by Loss of Siah2 Results in Increased Chemotherapeutic Efficacy

Christina S.F. Wong, Jaclyn Sceneay, Colin M. House, Heloise M. Halse, Mira C.P. Liu, Joshy George, Titaina C.U. Potdevin Hunnam, Belinda S. Parker, Izhak Haviv, Ze'ev Ronai, Carleen Cullinane, David D. Bowtell, Andreas Möller
Journal: Cancer Research
Cancer Res (2012) 72 (7): 1694–1704.
https://doi.org/10.1158/0008-5472.CAN-11-3310
Published: 01 April 2012
View article titled, Vascular Normalization by Loss of Siah2 Results in Increased Chemotherapeutic Efficacy
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Includes: Supplementary data
Journal Articles

A Dynamic Inflammatory Cytokine Network in the Human Ovarian Cancer Microenvironment

Hagen Kulbe, Probir Chakravarty, D. Andrew Leinster, Kellie A. Charles, Joseph Kwong, Richard G. Thompson, Jermaine I. Coward, Tiziana Schioppa, Stephen C. Robinson, William M. Gallagher, Laura Galletta, Michael A. Salako, John F. Smyth, Thorsten Hagemann, Donal J. Brennan, David D. Bowtell, Frances R. Balkwill
Journal: Cancer Research
Cancer Res (2012) 72 (1): 66–75.
https://doi.org/10.1158/0008-5472.CAN-11-2178
Published: 02 January 2012
View article titled, A Dynamic Inflammatory Cytokine Network in the Human Ovarian Cancer Microenvironment
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Includes: Supplementary data
Journal Articles

Abstract 2336: SFRP4 expression as a marker of invasion in gastric cancer

Rita A. Busuttil, Joshy George, Kylie Scott, Patrick Tan, Stephen Lade, David D. Bowtell, Alex Boussioutas
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2336.
https://doi.org/10.1158/1538-7445.AM2011-2336
Published: 15 April 2011
View article titled, Abstract 2336: SFRP4 expression as a marker of invasion in gastric cancer