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David Colcher
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Journal Articles

Combining Adoptive Cellular and Immunocytokine Therapies to Improve Treatment of B-Lineage Malignancy

Harjeet Singh, Lisa Marie Serrano, Timothy Pfeiffer, Simon Olivares, George McNamara, David D. Smith, Zaid Al-Kadhimi, Stephen J. Forman, Stephen D. Gillies, Michael C. Jensen, David Colcher, Andrew Raubitschek, Laurence J.N. Cooper
Journal: Cancer Research
Cancer Res (2007) 67 (6): 2872–2880.
https://doi.org/10.1158/0008-5472.CAN-06-2283
Published: 15 March 2007
View article titled, Combining Adoptive Cellular and Immunocytokine Therapies to Improve Treatment of B-Lineage Malignancy
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Includes: Multimedia, Supplementary data
Journal Articles

Radioiodinated versus Radiometal-Labeled Anti–Carcinoembryonic Antigen Single-Chain Fv-Fc Antibody Fragments: Optimal Pharmacokinetics for Therapy

Vania Kenanova, Tove Olafsen, Lawrence E. Williams, Nora H. Ruel, Jeffrey Longmate, Paul J. Yazaki, John E. Shively, David Colcher, Andrew A. Raubitschek, Anna M. Wu
Journal: Cancer Research
Cancer Res (2007) 67 (2): 718–726.
https://doi.org/10.1158/0008-5472.CAN-06-0454
Published: 18 January 2007
View article titled, Radioiodinated versus Radiometal-Labeled Anti–Carcinoembryonic Antigen Single-Chain Fv-Fc Antibody Fragments: Optimal Pharmacokinetics for Therapy
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Journal Articles

Penetratin Improves Tumor Retention of Single-Chain Antibodies: A Novel Step toward Optimization of Radioimmunotherapy of Solid Tumors

Maneesh Jain, Subhash C. Chauhan, Ajay P. Singh, Ganesh Venkatraman, David Colcher, Surinder K. Batra
Journal: Cancer Research
Cancer Res (2005) 65 (17): 7840–7846.
https://doi.org/10.1158/0008-5472.CAN-05-0662
Published: 01 September 2005
View article titled, Penetratin Improves Tumor Retention of Single-Chain Antibodies: A Novel Step toward Optimization of Radioimmunotherapy of Solid Tumors
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Journal Articles

Engineered anti-CEA scFv-Fc antibody fragments tailored for pharmacokinetic and imaging properties

Vania E. Kenanova, Tove Olafsen, Gobalakrishnan Sundaresan, Murugesan Subbarayan, Lawrence E. Williams, John E. Shively, David Colcher, Sanjiv S. Gambhir, Andrew A. Raubitschek, Anna M. Wu
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1243.
Published: 01 May 2005
View article titled, Engineered anti-CEA scFv-Fc antibody fragments tailored for pharmacokinetic and imaging properties
Journal Articles

Tailoring the Pharmacokinetics and Positron Emission Tomography Imaging Properties of Anti–Carcinoembryonic Antigen Single-Chain Fv-Fc Antibody Fragments

Vania Kenanova, Tove Olafsen, Desiree M. Crow, Gobalakrishnan Sundaresan, Murugesan Subbarayan, Nora H. Carter, David N. Ikle, Paul J. Yazaki, Arion F. Chatziioannou, Sanjiv S. Gambhir, Lawrence E. Williams, John E. Shively, David Colcher, Andrew A. Raubitschek, Anna M. Wu
Journal: Cancer Research
Cancer Res (2005) 65 (2): 622–631.
https://doi.org/10.1158/0008-5472.622.65.2
Published: 03 February 2005
View article titled, Tailoring the Pharmacokinetics and Positron Emission Tomography Imaging Properties of Anti–Carcinoembryonic Antigen Single-Chain Fv-Fc Antibody Fragments
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Journal Articles

Genetically Engineered Tetravalent Single-Chain Fv of the Pancarcinoma Monoclonal Antibody CC49: Improved Biodistribution and Potential for Therapeutic Application

Apollina Goel, David Colcher, Janina Baranowska-Kortylewicz, Sam Augustine, Barbara J. M. Booth, Gabriela Pavlinkova, Surinder K. Batra
Journal: Cancer Research
Cancer Res (2000) 60 (24): 6964–6971.
Published: 01 December 2000
View article titled, Genetically Engineered Tetravalent Single-Chain Fv of the Pancarcinoma Monoclonal Antibody CC49: Improved Biodistribution and Potential for Therapeutic Application
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Journal Articles

Therapeutic Advantage of High-Affinity Anticarcinoma Radioimmunoconjugates

Jeffrey Schlom, Diane Eggensperger, David Colcher, Alfredo Molinolo, David Houchens, Larry S. Miller, George Hinkle, Kathleen Siler
Journal: Cancer Research
Cancer Res (1992) 52 (5): 1067–1072.
Published: 01 March 1992
View article titled, Therapeutic Advantage of High-Affinity Anticarcinoma Radioimmunoconjugates
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Journal Articles

Pharmacokinetics and Immune Response of 131I-Chimeric Mouse/Human B72.3 (Human γ4) Monoclonal Antibody in Humans

M. B. Khazaeli, Mansoor N. Saleh, T. P. Liu, Ruby F. Meredith, Richard H. Wheeler, Terry S. Baker, David King, David Secher, Laquetta Allen, Kim Rogers, David Colcher, Jeffrey Schlom, Dan Shochat, Albert F. LoBuglio
Journal: Cancer Research
Cancer Res (1991) 51 (20): 5461–5466.
Published: 01 October 1991
View article titled, Pharmacokinetics and Immune Response of <sup>131</sup>I-Chimeric Mouse/Human B72.3 (Human γ4) Monoclonal Antibody in Humans
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Journal Articles

Monoclonal Antibody-based Therapy of a Human Tumor Xenograft with a 177Lutetium-labeled Immunoconjugate

Jeffrey Schlom, Kathleen Siler, Diane E. Milenic, Diane Eggensperger, David Colcher, Larry S. Miller, David Houchens, Roberta Cheng, Donald Kaplan, William Goeckeler
Journal: Cancer Research
Cancer Res (1991) 51 (11): 2889–2896.
Published: 01 June 1991
View article titled, Monoclonal Antibody-based Therapy of a Human Tumor Xenograft with a <sup>177</sup>Lutetium-labeled Immunoconjugate
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Journal Articles

Serological Mapping of the TAG-72 Tumor-associated Antigen Using 19 Distinct Monoclonal Antibodies

Masahide Kuroki, Philip D. Fernsten, David Wunderlich, David Colcher, Jean F. Simpson, Diane J. Poole, Jeffrey Schlom
Journal: Cancer Research
Cancer Res (1990) 50 (16): 4872–4879.
Published: 01 August 1990
View article titled, Serological Mapping of the TAG-72 Tumor-associated Antigen Using 19 Distinct Monoclonal Antibodies
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Journal Articles

Innovations That Influence the Pharmacology of Monoclonal Antibody Guided Tumor Targeting

Jeffrey Schlom, Patricia Horan Hand, John W. Greiner, David Colcher, Shashi Shrivastav, Jorge A. Carrasquillo, James C. Reynolds, Steven M. Larson, Andrew Raubitschek
Journal: Cancer Research
Cancer Res (1990) 50 (3_Supplement): 820s–827s.
Published: 01 February 1990
View article titled, Innovations That Influence the Pharmacology of Monoclonal Antibody Guided Tumor Targeting
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Journal Articles

Characterization and Biodistribution of Recombinant and Recombinant/Chimeric Constructs of Monoclonal Antibody B72.3

David Colcher, Diane Milenic, Mario Roselli, Andrew Raubitschek, Geoffrey Yarranton, David King, John Adair, Nigel Whittle, Mark Bodmer, Jeffrey Schlom
Journal: Cancer Research
Cancer Res (1989) 49 (7): 1738–1745.
Published: 01 April 1989
View article titled, Characterization and Biodistribution of Recombinant and Recombinant/Chimeric Constructs of Monoclonal Antibody B72.3
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Journal Articles

Radioimmunolocalization of Human Carcinoma Xenografts with B72.3 Second Generation Monoclonal Antibodies

David Colcher, Maria Filomena Minelli, Mario Roselli, Raffaella Muraro, Diane Simpson-Milenic, Jeffrey Schlom
Journal: Cancer Research
Cancer Res (1988) 48 (16): 4597–4603.
Published: 01 August 1988
View article titled, Radioimmunolocalization of Human Carcinoma Xenografts with B72.3 Second Generation Monoclonal Antibodies
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Journal Articles

Generation and Characterization of B72.3 Second Generation Monoclonal Antibodies Reactive with the Tumor-associated Glycoprotein 72 Antigen

Raffaella Muraro, Masahide Kuroki, David Wunderlich, Diane J. Poole, David Colcher, Ann Thor, John W. Greiner, Jean F. Simpson, Alfredo Molinolo, Philip Noguchi, Jeffrey Schlom
Journal: Cancer Research
Cancer Res (1988) 48 (16): 4588–4596.
Published: 01 August 1988
View article titled, Generation and Characterization of B72.3 Second Generation Monoclonal Antibodies Reactive with the Tumor-associated Glycoprotein 72 Antigen
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Journal Articles

Localization and Imaging of Radiolabeled Monoclonal Antibodies against Colorectal Carcinoma in Tumor-bearing Nude Mice

Donald Buchsbaum, Ricardo Lloyd, Jack Juni, Ira Wollner, Pamela Brubaker, David Hanna, Judith Spicker, Felissa Burns, Zenon Steplewski, David Colcher, Jeffrey Schlom, Franz Buchegger, Jean-Pierre Mach
Journal: Cancer Research
Cancer Res (1988) 48 (15): 4324–4333.
Published: 01 August 1988
View article titled, Localization and Imaging of Radiolabeled Monoclonal Antibodies against Colorectal Carcinoma in Tumor-bearing Nude Mice
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Journal Articles

Complementation of Intracavitary and Intravenous Administration of a Monoclonal Antibody (B72.3) in Patients with Carcinoma

David Colcher, Jose Esteban, Jorge A. Carrasquillo, Paul Sugarbaker, James C. Reynolds, Gail Bryant, Steven M. Larson, Jeffrey Schlom
Journal: Cancer Research
Cancer Res (1987) 47 (15): 4218–4224.
Published: 01 August 1987
View article titled, Complementation of Intracavitary and Intravenous Administration of a Monoclonal Antibody (B72.3) in Patients with Carcinoma
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Journal Articles

Differential Expression of Carcinoembryonic Antigen in Early Gastric Adenocarcinomas versus Benign Gastric Lesions Defined by Monoclonal Antibodies Reactive with Restricted Antigen Epitopes

Noriaki Ohuchi, Dave Wunderlich, Jun Fujita, David Colcher, Raffaella Muraro, Masato Nose, Jeffrey Schlom
Journal: Cancer Research
Cancer Res (1987) 47 (13): 3565–3571.
Published: 01 July 1987
View article titled, Differential Expression of Carcinoembryonic Antigen in Early Gastric Adenocarcinomas <em>versus</em> Benign Gastric Lesions Defined by Monoclonal Antibodies Reactive with Restricted Antigen Epitopes
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Journal Articles

Quantitative Analyses of Selective Radiolabeled Monoclonal Antibody Localization in Metastatic Lesions of Colorectal Cancer Patients

David Colcher, Jose M. Esteban, Jorge A. Carrasquillo, Paul Sugarbaker, James C. Reynolds, Gail Bryant, Steven M. Larson, Jeffrey Schlom
Journal: Cancer Research
Cancer Res (1987) 47 (4): 1185–1189.
Published: 01 February 1987
View article titled, Quantitative Analyses of Selective Radiolabeled Monoclonal Antibody Localization in Metastatic Lesions of Colorectal Cancer Patients
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Journal Articles

Pharmacokinetics of Radiolabeled Monoclonal Antibody B6.2 in Patients with Metastatic Breast Cancer

Daniel F. Hayes, Michael R. Zalutsky, William Kaplan, Michael Noska, Ann Thor, David Colcher, Donald W. Kufe
Journal: Cancer Research
Cancer Res (1986) 46 (6): 3157–3163.
Published: 01 June 1986
View article titled, Pharmacokinetics of Radiolabeled Monoclonal Antibody B6.2 in Patients with Metastatic Breast Cancer
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Journal Articles

Analysis of a Human Tumor-associated Glycoprotein (TAG-72) Identified by Monoclonal Antibody B72.3

Virginia G. Johnson, Jeffrey Schlom, Andrew J. Paterson, Jeffrey Bennett, John L. Magnani, David Colcher
Journal: Cancer Research
Cancer Res (1986) 46 (2): 850–857.
Published: 01 February 1986
View article titled, Analysis of a Human Tumor-associated Glycoprotein (TAG-72) Identified by Monoclonal Antibody B72.3
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