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David A. Wink
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Journal Articles

Abstract 347: Tumor necrosis factor related apoptosis inducing ligand (TRAIL)-induced cytokine production in TNBC promotes neutrophil chemotaxis and immune suppression

Manjari Kundu, Yoshimi Endo Greer, Lisa Ann Ridnour, David A Wink, Yeap S. Ng, Roberto Weigert, Stan Lipkowitz
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 347.
https://doi.org/10.1158/1538-7445.AM2024-347
Published: 22 March 2024
View article titled, Abstract 347: Tumor necrosis factor related apoptosis inducing ligand (TRAIL)-induced cytokine production in TNBC promotes neutrophil chemotaxis and immune suppression
Journal Articles

Abstract 2539: Tumor necrosis factor related apoptosis inducing ligand (TRAIL) induces cytokine release via the alternative NFKB2 pathway in triple negative breast cancer cells (TNBC) and modulates neutrophil chemotaxis

Manjari Kundu, Yoshimi Endo Greer, Lisa A. Ridnour, David A. Wink, Stan Lipkowitz
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2539.
https://doi.org/10.1158/1538-7445.AM2023-2539
Published: 04 April 2023
View article titled, Abstract 2539: Tumor necrosis factor related apoptosis inducing ligand (TRAIL) induces cytokine release via the alternative NFKB2 pathway in triple negative breast cancer cells (TNBC) and modulates neutrophil chemotaxis
Journal Articles

Abstract 6071: Role of nitric oxide in the invasive pancreatic cancer cells

Mayumi Fujita, Veena Somasundaram, Debashree Basudhar Basudhar, Robert Y.s. Cheng, Lisa A. Ridnour, Kaori Imadome, Jae Hong No, Gaurav Bharadwaj, David A. Wink
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6071.
https://doi.org/10.1158/1538-7445.AM2020-6071
Published: 15 August 2020
View article titled, Abstract 6071: Role of nitric oxide in the invasive pancreatic cancer cells
Journal Articles

Abstract 6198: Regulation of cycloxygenase-2 in the tumor micro-environment improves radiation and immunotherapy

Debashree Basudhar, Veena Somasundaram, David A. Scheiblin, Noemi Kedei, Robert Y. Cheng, Lisa A. Ridnour, Daniel W. McVicar, Stephen Lockett, David A. Wink
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6198.
https://doi.org/10.1158/1538-7445.AM2020-6198
Published: 15 August 2020
View article titled, Abstract 6198: Regulation of cycloxygenase-2 in the tumor micro-environment improves radiation and immunotherapy
Journal Articles

Abstract 2754: Inhibition of nitric oxide synthase and cyclooxygenase potentiate immune responses that control aggressive mammary tumor in a murine model

Veena Somasundaram, Debashree Basudhar, Christopher McGinity, Robert Y. Cheng, Lisa A. Ridnour, Stephen J. Lockett, David A. Wink
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2754.
https://doi.org/10.1158/1538-7445.AM2020-2754
Published: 15 August 2020
View article titled, Abstract 2754: Inhibition of nitric oxide synthase and cyclooxygenase potentiate immune responses that control aggressive mammary tumor in a murine model
Journal Articles

Abstract 1186: Regulation of inducible nitric oxide synthase at the single cell level modulates the inflammatory microenvironment

Veena Somasundaram, Caroline Gilmore, Erika M. Palmieri, Debashree Basudhar, Will Heinz, Robert Y. Cheng, Lisa A. Ridnour, Stephen J. Lockett, Daniel W. McVicar, David A. Wink
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1186.
https://doi.org/10.1158/1538-7445.AM2019-1186
Published: 01 July 2019
View article titled, Abstract 1186: Regulation of inducible nitric oxide synthase at the single cell level modulates the inflammatory microenvironment
Journal Articles

Abstract 5500: Nitric oxide donor DETA/NO inhibits the growth of endometrial cancer cells by upregulating expression of RASSF1 and CDKN1

Hannah Taitz, Ana Paucarmayta, Robert Cheng, George L. Maxwell, Chad A. Hamilton, David A. Wink, Viqar Syed
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5500.
https://doi.org/10.1158/1538-7445.AM2018-5500
Published: 01 July 2018
View article titled, Abstract 5500: Nitric oxide donor DETA/NO inhibits the growth of endometrial cancer cells by upregulating expression of RASSF1 and CDKN1
Journal Articles

Abstract 3789: Role of NOS2-COX2 crosstalk in tumor microenvironment of estrogen receptor-negative breast cancer and its therapeutic implications

Debashree Basudhar, Sharon Glynn, Madison Greer, Veena Somasundaram, Jae H. No, David A. Scheiblin, Pablo Garrido, William F. Heinz, Aideen E. Ryan, Jonathan M. Weiss, Robert Y. Cheng, Lisa A. Ridnour, Stephen J. Lockett, Daniel W. McVicar, Stefan Ambs, David A. Wink
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3789.
https://doi.org/10.1158/1538-7445.AM2018-3789
Published: 01 July 2018
View article titled, Abstract 3789: Role of NOS2-COX2 crosstalk in tumor microenvironment of estrogen receptor-negative breast cancer and its therapeutic implications
Journal Articles

Abstract 4497: Delineating the effects of different levels of nitric oxide produced by "M1" stimulated macrophages on tumor rejection and response to therapy

Veena Somasundaram, Debashree Basudhar, Erika M. Palmieri, Robert Y. Cheng, Lisa A. Ridnour, Daniel W. McVicar, David A. Wink
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4497.
https://doi.org/10.1158/1538-7445.AM2018-4497
Published: 01 July 2018
View article titled, Abstract 4497: Delineating the effects of different levels of nitric oxide produced by "M1" stimulated macrophages on tumor rejection and response to therapy
Journal Articles

Abstract 4539: Nitroxide-aspirin conjugates: A new class of NSAIDs

Terry W. Moody, Robert T. Jensen, Komba Thomas, Kathryn E. Fairfull-Smith, Steven E. Bottle, Lisa Ridnour, David A. Wink
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4539.
https://doi.org/10.1158/1538-7445.AM2015-4539
Published: 01 August 2015
View article titled, Abstract 4539: Nitroxide-aspirin conjugates: A new class of NSAIDs
Journal Articles

Abstract 4140: Role of nitric oxide in invasiveness of tumor cells irradiated with carbon-ion beams

Mayumi Fujita, Kaori Imadome, Yoshimi Shoji, Robert Cheng, Aparna H. Kesarwala, David A. Wink, Takashi Imai
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4140.
https://doi.org/10.1158/1538-7445.AM2015-4140
Published: 01 August 2015
View article titled, Abstract 4140: Role of nitric oxide in invasiveness of tumor cells irradiated with carbon-ion beams
Journal Articles

NOS Inhibition Modulates Immune Polarization and Improves Radiation-Induced Tumor Growth Delay

Lisa A. Ridnour, Robert Y.S. Cheng, Jonathan M. Weiss, Sukhbir Kaur, David R. Soto-Pantoja, Debashree Basudhar, Julie L. Heinecke, C. Andrew Stewart, William DeGraff, Anastasia L. Sowers, Angela Thetford, Aparna H. Kesarwala, David D. Roberts, Howard A. Young, James B. Mitchell, Giorgio Trinchieri, Robert H. Wiltrout, David A. Wink
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (14): 2788–2799.
https://doi.org/10.1158/0008-5472.CAN-14-3011
Published: 14 July 2015
View article titled, NOS Inhibition Modulates Immune Polarization and Improves Radiation-Induced Tumor Growth Delay
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Includes: Supplementary data
Journal Articles

CD47 in the Tumor Microenvironment Limits Cooperation between Antitumor T-cell Immunity and Radiotherapy

David R. Soto-Pantoja, Masaki Terabe, Arunima Ghosh, Lisa A. Ridnour, William G. DeGraff, David A. Wink, Jay A. Berzofsky, David D. Roberts
Journal: Cancer Research
Cancer Res (2014) 74 (23): 6771–6783.
https://doi.org/10.1158/0008-5472.CAN-14-0037-T
Published: 30 November 2014
View article titled, CD47 in the Tumor Microenvironment Limits Cooperation between Antitumor T-cell Immunity and Radiotherapy
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Includes: Supplementary data
Journal Articles

Dithiolethiones Inhibit NF-κB Activity via Covalent Modification in Human Estrogen Receptor–Negative Breast Cancer

Christopher H. Switzer, Robert Y.-S. Cheng, Lisa A. Ridnour, Margaret C. Murray, Valerio Tazzari, Anna Sparatore, Piero Del Soldato, Harry B. Hines, Sharon A. Glynn, Stefan Ambs, David A. Wink
Journal: Cancer Research
Cancer Res (2012) 72 (9): 2394–2404.
https://doi.org/10.1158/0008-5472.CAN-11-3115
Published: 30 April 2012
View article titled, Dithiolethiones Inhibit NF-κB Activity via Covalent Modification in Human Estrogen Receptor–Negative Breast Cancer
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Includes: Supplementary data
Journal Articles

Abstract 5594: Immunotherapy of metastastic renal cell carcinoma reveals a critical role for nitric oxide expression in the control of lung metastases but not primary tumors

Jonathan M. Weiss, Lisa Ridnour, Perwez Hussein, Peijun He, Timothy C. Back, Tony Scarzello, Anna E. Maciag, Larry Keefer, William J. Murphy, Curtis C. Harris, David A. Wink, Robert H. Wiltrout
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5594.
https://doi.org/10.1158/1538-7445.AM10-5594
Published: 15 April 2010
View article titled, Abstract 5594: Immunotherapy of metastastic renal cell carcinoma reveals a critical role for nitric oxide expression in the control of lung metastases but not primary tumors
Journal Articles

Thrombospondin 1 Promotes Tumor Macrophage Recruitment and Enhances Tumor Cell Cytotoxicity of Differentiated U937 Cells

Gema Martin-Manso, Susana Galli, Lisa A. Ridnour, Maria Tsokos, David A. Wink, David D. Roberts
Journal: Cancer Research
Cancer Res (2008) 68 (17): 7090–7099.
https://doi.org/10.1158/0008-5472.CAN-08-0643
Published: 28 August 2008
View article titled, Thrombospondin 1 Promotes Tumor Macrophage Recruitment and Enhances Tumor Cell Cytotoxicity of Differentiated U937 Cells
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Journal Articles

Asbestos Redirects Nitric Oxide Signaling through Rapid Catalytic Conversion to Nitrite

Douglas D. Thomas, Michael G. Espey, Derek A. Pociask, Lisa A. Ridnour, Sonia Donzelli, David A. Wink
Journal: Cancer Research
Cancer Res (2006) 66 (24): 11600–11604.
https://doi.org/10.1158/0008-5472.CAN-06-1140
Published: 18 December 2006
View article titled, Asbestos Redirects Nitric Oxide Signaling through Rapid Catalytic Conversion to Nitrite
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Journal Articles

Regulation of Transforming Growth Factor β1 by Nitric Oxide

Yoram Vodovotz, Louis Chesler, Hyonkyong Chong, Seong-Jin Kim, John T. Simpson, William DeGraff, George W. Cox, Anita B. Roberts, David A. Wink, Mary Helen Barcellos-Hoff
Journal: Cancer Research
Cancer Res (1999) 59 (9): 2142–2149.
Published: 01 May 1999
View article titled, Regulation of Transforming Growth Factor β1 by Nitric Oxide
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Journal Articles

In Vivo Radiation Protection by Nitric Oxide Modulation

James Liebmann, Anne Marie DeLuca, Deborah Coffin, Larry K. Keefer, David Venzon, David A. Wink, James B. Mitchell
Journal: Cancer Research
Cancer Res (1994) 54 (13): 3365–3368.
Published: 01 July 1994
View article titled, <em>In Vivo</em> Radiation Protection by Nitric Oxide Modulation
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Journal Articles

Hypoxic Mammalian Cell Radiosensitization by Nitric Oxide

James B. Mitchell, David A. Wink, William DeGraff, Janet Gamson, Larry K. Keefer, Murali C. Krishna
Journal: Cancer Research
Cancer Res (1993) 53 (24): 5845–5848.
Published: 01 December 1993
View article titled, Hypoxic Mammalian Cell Radiosensitization by Nitric Oxide
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