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David A. Mankoff
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Journal Articles

Abstract 5610: [18F]FluorThanatrace ([18F]FTT) PET Imaging of PARP-inhibitor drug-target engagement as a biomarker of response in ovarian cancer

Sarah B. Gitto, Austin R. Pantel, Mehran Makvandi, Hyoung Kim, Sergey Medvedev, Joanna K. Weeks, Drew A. Torigian, Chia-Ju Hsieh, Benjamin Ferman, Nawar A. Latif, Janos L. Tanyi, Lainie P. Martin, Shannon M. Lanzo, Fang Liu, Quy Cao, Gordon B. Mills, Robert K. Doot, David A. Mankoff, Robert H. Mach, Lilie L. Lin, Fiona Simpkins
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5610.
https://doi.org/10.1158/1538-7445.AM2023-5610
Published: 04 April 2023
View article titled, Abstract 5610: [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-inhibitor drug-target engagement as a biomarker of response in ovarian cancer
Journal Articles

Abstract P2-03-17: Fluoroestradiol (FES) and Fluorodeoxyglucose (FDG) PET imaging in patients with ER+, HER2+ or HER2- metastatic breast cancer

Natasha Hunter, Lanell M. Peterson, David A. Mankoff, Mark Muzi, Delphine Chen, William R. Gwin, Shaveta Vinayak, Nancy E Davidson, Jennifer M. Specht, Hannah Linden
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P2-03-17.
https://doi.org/10.1158/1538-7445.SABCS22-P2-03-17
Published: 01 March 2023
View article titled, Abstract P2-03-17: Fluoroestradiol (FES) and Fluorodeoxyglucose (FDG) PET imaging in patients with ER+, HER2+ or HER2- metastatic breast cancer
Journal Articles

A PET Glutamate Analogue to Measure Cancer Cell Redox State and Oxidative Stress: Promise and Paradox

Hsiaoju S. Lee, Austin R. Pantel, Rong Zhou, David A. Mankoff
Journal: Cancer Research
Cancer Res (2019) 79 (4): 701–703.
https://doi.org/10.1158/0008-5472.CAN-18-4034
Published: 15 February 2019
View article titled, A PET Glutamate Analogue to Measure Cancer Cell Redox State and Oxidative Stress: Promise and Paradox
Open the PDF for A PET Glutamate Analogue to Measure Cancer Cell Redox State and Oxidative Stress: Promise and Paradox in another window
Journal Articles

Glutamate-Weighted Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Detects Glutaminase Inhibition in a Mouse Model of Triple-Negative Breast Cancer

Rong Zhou, Puneet Bagga, Kavindra Nath, Hari Hariharan, David A. Mankoff, Ravinder Reddy
Journal: Cancer Research
Cancer Res (2018) 78 (19): 5521–5526.
https://doi.org/10.1158/0008-5472.CAN-17-3988
Published: 01 October 2018
View article titled, Glutamate-Weighted Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Detects Glutaminase Inhibition in a Mouse Model of Triple-Negative Breast Cancer
Open the PDF for Glutamate-Weighted Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Detects Glutaminase Inhibition in a Mouse Model of Triple-Negative Breast Cancer in another window
Journal Articles

Abstract 3716: Exploring the significance of PARP-1 expression for therapy and clinical PET/CT imaging of PARP-1 in ovarian cancer

Mehran Makvandi, Austin Pantel, Lauren E. Schwartz, Kuiying Xu, Chia-Ju Hsieh, Hyoung Kim, Shi-Hong Li, Robert Doot, Sharon Lee, Fiona Simpkins, Roger A. Greenberg, David A. Mankoff, Robert H. Mach, Lilie Lin
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3716.
https://doi.org/10.1158/1538-7445.AM2017-3716
Published: 01 July 2017
View article titled, Abstract 3716: Exploring the significance of PARP-1 expression for therapy and clinical PET/CT imaging of PARP-1 in ovarian cancer
Journal Articles

Abstract 5710: PGRMC1 is a biomarker for breast cancer cell proliferation and early relapse

Elizabeth S. McDonald, Dhruv K. Pant, Tien-chi Pan, David A. Mankoff, Robert H. Mach, Lewis A. Chodosh
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5710.
https://doi.org/10.1158/1538-7445.AM2017-5710
Published: 01 July 2017
View article titled, Abstract 5710: <em>PGRMC1</em> is a biomarker for breast cancer cell proliferation and early relapse
Journal Articles

Abstract 2851: Cellular glutamine pool size change in response to glutaminase inhibition detected by kinetic analysis of [18F](2S,4R)4-fluoroglutamine PET

Austin R. Pantel, Hsiaoju Lee, Shihong Li, Robert K. Doot, Robert H. Mach, David A. Mankoff, Rong Zhou
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2851.
https://doi.org/10.1158/1538-7445.AM2017-2851
Published: 01 July 2017
View article titled, Abstract 2851: Cellular glutamine pool size change in response to glutaminase inhibition detected by kinetic analysis of [<sup>18</sup>F](2S,4R)4-fluoroglutamine PET
Journal Articles

Abstract SY02-03: Imaging cancer metabolism in patients: FDG PET and beyond

David A. Mankoff
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): SY02-03.
https://doi.org/10.1158/1538-7445.AM2017-SY02-03
Published: 01 July 2017
View article titled, Abstract SY02-03: Imaging cancer metabolism in patients: FDG PET and beyond
Journal Articles

[18F](2S,4R)4-Fluoroglutamine PET Detects Glutamine Pool Size Changes in Triple-Negative Breast Cancer in Response to Glutaminase Inhibition

Rong Zhou, Austin R. Pantel, Shihong Li, Brian P. Lieberman, Karl Ploessl, Hoon Choi, Eric Blankemeyer, Hsiaoju Lee, Hank F. Kung, Robert H. Mach, David A. Mankoff
Journal: Cancer Research
Cancer Res (2017) 77 (6): 1476–1484.
https://doi.org/10.1158/0008-5472.CAN-16-1945
Published: 14 March 2017
View article titled, [<sup>18</sup>F](2<em>S</em>,4<em>R</em>)4-Fluoroglutamine PET Detects Glutamine Pool Size Changes in Triple-Negative Breast Cancer in Response to Glutaminase Inhibition
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Includes: Supplementary data
Journal Articles

Abstract 3791: PGRMC1 expression is significantly up-regulated in triple negative breast cancer in vivo with associated activation of cyclin D1 target genes: Analysis of 1019 invasive breast cancers in the TCGA database

Elizabeth S. McDonald, Chenbo Zeng, David A. Mankoff, Andrew Kossenkov, Robert H. Mach
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3791.
https://doi.org/10.1158/1538-7445.AM2015-3791
Published: 01 August 2015
View article titled, Abstract 3791: PGRMC1 expression is significantly up-regulated in triple negative breast cancer <em>in vivo</em> with associated activation of cyclin D1 target genes: Analysis of 1019 invasive breast cancers in the TCGA database
Journal Articles

Abstract SY42-02: Novel PET imaging in the clinic: Selecting patient cohorts and measuring early response

Janet F. Eary, Jeanne M. Link, David A. Mankoff, Mark Muzi, Finbarr O'Sullivan, James R. Fink, Jason K. Rockhill, Hannah M. Linden, Kenneth A. Krohn
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): SY42-02.
https://doi.org/10.1158/1538-7445.AM2012-SY42-02
Published: 15 April 2012
View article titled, Abstract SY42-02: Novel PET imaging in the clinic: Selecting patient cohorts and measuring early response
Journal Articles

2-[C-11]Thymidine Imaging of Malignant Brain Tumors

Janet F. Eary, David A. Mankoff, Alexander M. Spence, Mitchel S. Berger, Adam Olshen, Jeanne M. Link, Finbarr O’Sullivan, Kenneth A. Krohn
Journal: Cancer Research
Cancer Res (1999) 59 (3): 615–621.
Published: 01 February 1999
View article titled, 2-[C-11]Thymidine Imaging of Malignant Brain Tumors
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