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Journal Articles

Abstract 902: The antiandrogen bicalutamide induces senescence in LNCaP cells and quiescence in Myc CaP cells

Valerie J. Carpenter, Tareq Saleh, David A. Gewirtz

Cancer Res (2019) 79 (13_Supplement): 902.

https://doi.org/10.1158/1538-7445.AM2019-902

Published: 01 July 2019

View article titled, Abstract 902: The antiandrogen bicalutamide induces senescence in LNCaP cells and quiescence in Myc CaP cells

Journal Articles

Abstract 901: Elimination of senescent tumor cells by ABT263 interferes with proliferative recovery and provides a two-hit therapeutic approach

Tareq Saleh, Liliya Tyutyunyk-Massey, Graeme F. Murray, Moureq R. Alotaibi, Ajinkya S. Kawale, Zeinab Elsayed, Scott C. Henderson, Vasily Yakovlev, Lynne W. Elmore, Amir Toor, Hisashi Harada, Jason Reed, Joseph W. Landry, David A. Gewirtz

Cancer Res (2019) 79 (13_Supplement): 901.

https://doi.org/10.1158/1538-7445.AM2019-901

Published: 01 July 2019

View article titled, Abstract 901: Elimination of senescent tumor cells by ABT263 interferes with proliferative recovery and provides a two-hit therapeutic approach

Journal Articles

Abstract 899: Selective clearance of cells undergoing therapy-induced senescence in a model of triple negative breast cancer

Liliya Tyutyunyk, Tareq Saleh, David A. Gewirtz

Cancer Res (2019) 79 (13_Supplement): 899.

https://doi.org/10.1158/1538-7445.AM2019-899

Published: 01 July 2019

View article titled, Abstract 899: Selective clearance of cells undergoing therapy-induced senescence in a model of triple negative breast cancer

Journal Articles

Abstract 4272: Suppression of epigenetic regulator NURF leads to autophagy mediated chemo-and immune sensitization of triple negative breast cancer

Liliya Tyutyunyk, David A. Gewirtz, Joseph Landry, Nga Dao

Cancer Res (2019) 79 (13_Supplement): 4272.

https://doi.org/10.1158/1538-7445.AM2019-4272

Published: 01 July 2019

View article titled, Abstract 4272: Suppression of epigenetic regulator NURF leads to autophagy mediated chemo-and immune sensitization of triple negative breast cancer

Journal Articles

Abstract 4278: A comparison of drug sensitivity in isogenic tumor cell lines confirms that cytoprotective autophagy confers intrinsic resistance to cisplatin

Jingwen Xu, Nipa Patel, Tareq Saleh, Yingliang Wu, Santiago Lima, David A. Gewirtz

Cancer Res (2019) 79 (13_Supplement): 4278.

https://doi.org/10.1158/1538-7445.AM2019-4278

Published: 01 July 2019

View article titled, Abstract 4278: A comparison of drug sensitivity in isogenic tumor cell lines confirms that cytoprotective autophagy confers intrinsic resistance to cisplatin

Journal Articles

Tumor Cell Escape from Therapy-Induced Senescence as a Model of Disease Recurrence after Dormancy

Tareq Saleh, Liliya Tyutyunyk-Massey, David A. Gewirtz

Cancer Res (2019) 79 (6): 1044–1046.

https://doi.org/10.1158/0008-5472.CAN-18-3437

Published: 15 March 2019

View article titled, Tumor Cell Escape from Therapy-Induced Senescence as a Model of Disease Recurrence after Dormancy

Journal Articles

Abstract 459: Therapy-induced senescence is reversible in vitro and in vivo

Tareq Saleh, Moureq R. Alotaibi, Sarah L. Kyte, Emmanuel K. Cudjoe, Ajinkya Kawale, Jingwen Xu, Zeinab Elsayed, Joseph W. Landry, Scott C. Henderson, Vasily Yakovlev, Lynne W. Elmore, David A. Gewirtz

Cancer Res (2018) 78 (13_Supplement): 459.

https://doi.org/10.1158/1538-7445.AM2018-459

Published: 01 July 2018

View article titled, Abstract 459: Therapy-induced senescence is reversible in vitro and in vivo

Journal Articles

Abstract 602: The α7 nicotinic acetylcholine receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy without enhancing the proliferation of lung cancer cells or interfering with paclitaxel-induced antitumor activity

S Lauren Kyte, Wisam Toma, Ganeshsingh Thakur, M Imad Damaj, David A. Gewirtz

Cancer Res (2018) 78 (13_Supplement): 602.

https://doi.org/10.1158/1538-7445.AM2018-602

Published: 01 July 2018

View article titled, Abstract 602: The α7 nicotinic acetylcholine receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy without enhancing the proliferation of lung cancer cells or interfering with paclitaxel-induced antitumor activity

Journal Articles

Abstract 227: Mass spectrometry-based proteomics analysis of the non-small cell lung cancer secretome

Emmanuel K. Cudjoe, Tareq Saleh, David A. Gewirtz, Adam M. Hawkridge

Cancer Res (2017) 77 (13_Supplement): 227.

https://doi.org/10.1158/1538-7445.AM2017-227

Published: 01 July 2017

View article titled, Abstract 227: Mass spectrometry-based proteomics analysis of the non-small cell lung cancer secretome

Journal Articles

Abstract 3299: Radiation induced p53-dependent cytoprotective autophagy fails to reduce radiation sensitivity in H460 non-small cell lung cancer cells

Jingwen Xu, Tareq Saleh, Liliya Tyutynuk-Massey, Yingliang Wu, David A. Gewirtz

Cancer Res (2017) 77 (13_Supplement): 3299.

https://doi.org/10.1158/1538-7445.AM2017-3299

Published: 01 July 2017

View article titled, Abstract 3299: Radiation induced p53-dependent cytoprotective autophagy fails to reduce radiation sensitivity in H460 non-small cell lung cancer cells

Journal Articles

Abstract 986: Targeting nicotinic acetylcholine receptors for the prevention and reversal of chemotherapy-induced peripheral neuropathy

S Lauren Kyte, Wisam Toma, Ganeshsingh Thakur, M Imad Damaj, David A. Gewirtz

Cancer Res (2017) 77 (13_Supplement): 986.

https://doi.org/10.1158/1538-7445.AM2017-986

Published: 01 July 2017

View article titled, Abstract 986: Targeting nicotinic acetylcholine receptors for the prevention and reversal of chemotherapy-induced peripheral neuropathy

Journal Articles

Abstract 5459: Autophagy and senescence as possible mechanisms leading to proliferative recovery and escape from treatment-induced tumor dormancy

Liliya Tyutyunyk, Theresa Thekkudan, Tareq Saleh, David A. Gewirtz

Cancer Res (2017) 77 (13_Supplement): 5459.

https://doi.org/10.1158/1538-7445.AM2017-5459

Published: 01 July 2017

View article titled, Abstract 5459: Autophagy and senescence as possible mechanisms leading to proliferative recovery and escape from treatment-induced tumor dormancy

Journal Articles

Abstract 5470: Reversibility of therapy-induced senescence in non-small cell lung cancer as a model of cancer recurrence

Tareq Saleh, Emmanuel K. Cudjoe, S Lauren Kyte, Scott C. Henderson, Lynne W. Elmore, David A. Gewirtz

Cancer Res (2017) 77 (13_Supplement): 5470.

https://doi.org/10.1158/1538-7445.AM2017-5470

Published: 01 July 2017

View article titled, Abstract 5470: Reversibility of therapy-induced senescence in non-small cell lung cancer as a model of cancer recurrence

Journal Articles

The Challenge of Developing Autophagy Inhibition as a Therapeutic Strategy

David A. Gewirtz

Cancer Res (2016) 76 (19): 5610–5614.

https://doi.org/10.1158/0008-5472.CAN-16-0722

Published: 02 October 2016

View article titled, The Challenge of Developing Autophagy Inhibition as a Therapeutic Strategy

Journal Articles

Abstract 2846: Proliferative recovery after chemotherapy-induced senescence in non-small cell lung cancer (NSCLC) cells as a model of tumor dormancy and disease recurrence

Tareq Saleh, Theresa Thekkudan, Moureq R. Alotaibi, David A. Gewirtz

Cancer Res (2016) 76 (14_Supplement): 2846.

https://doi.org/10.1158/1538-7445.AM2016-2846

Published: 15 July 2016

View article titled, Abstract 2846: Proliferative recovery after chemotherapy-induced senescence in non-small cell lung cancer (NSCLC) cells as a model of tumor dormancy and disease recurrence

Journal Articles

Abstract 3574: Nicotine prevents chemotherapy-induced peripheral neuropathy in vivo, and fails to stimulate the growth of lung cancer cells or interfere with the effectiveness of chemotherapy in vitro

Sarah L. Kyte, Wisam Toma, M I. Damaj, Xianjun Fang, David A. Gewirtz

Cancer Res (2016) 76 (14_Supplement): 3574.

https://doi.org/10.1158/1538-7445.AM2016-3574

Published: 15 July 2016

View article titled, Abstract 3574: Nicotine prevents chemotherapy-induced peripheral neuropathy in vivo, and fails to stimulate the growth of lung cancer cells or interfere with the effectiveness of chemotherapy in vitro

Journal Articles

The Four Faces of Autophagy: Implications for Cancer Therapy

David A. Gewirtz

Cancer Res (2014) 74 (3): 647–651.

https://doi.org/10.1158/0008-5472.CAN-13-2966

Published: 02 February 2014

View article titled, The Four Faces of Autophagy: Implications for Cancer Therapy

Journal Articles

Abstract 5665: New alternatives to photodynamic therapy based on light-enabled drug delivery.

M. Michael Dcona, Deboleena Mitra, Rachel W. Goehe, David A. Gewirtz, Deborah A. Lebman, Matthew C.T. Hartman

Cancer Res (2013) 73 (8_Supplement): 5665.

https://doi.org/10.1158/1538-7445.AM2013-5665

Published: 15 April 2013

View article titled, Abstract 5665: New alternatives to photodynamic therapy based on light-enabled drug delivery.

Journal Articles

Abstract 1453: The cannabinoid Win55, 212-2 enhances the response of breast cancer cells to radiation

Sean M. Emery, Evan T. Sumner, Aron H. Lichtman, David A. Gewirtz

Cancer Res (2012) 72 (8_Supplement): 1453.

https://doi.org/10.1158/1538-7445.AM2012-1453

Published: 15 April 2012

View article titled, Abstract 1453: The cannabinoid Win55, 212-2 enhances the response of breast cancer cells to radiation

Journal Articles

Abstract 1465: Radiosensitization of NSCLC through modulation of autophagy and senescence

Rachel W. Goehe, Khushboo Sharma, Aparna Maiti, David A. Gewirtz

Cancer Res (2012) 72 (8_Supplement): 1465.

https://doi.org/10.1158/1538-7445.AM2012-1465

Published: 15 April 2012

View article titled, Abstract 1465: Radiosensitization of NSCLC through modulation of autophagy and senescence

NARROW

Abstract 902: The antiandrogen bicalutamide induces senescence in LNCaP cells and quiescence in Myc CaP cells

Abstract 901: Elimination of senescent tumor cells by ABT263 interferes with proliferative recovery and provides a two-hit therapeutic approach

Abstract 899: Selective clearance of cells undergoing therapy-induced senescence in a model of triple negative breast cancer

Abstract 4272: Suppression of epigenetic regulator NURF leads to autophagy mediated chemo-and immune sensitization of triple negative breast cancer

Abstract 4278: A comparison of drug sensitivity in isogenic tumor cell lines confirms that cytoprotective autophagy confers intrinsic resistance to cisplatin

Tumor Cell Escape from Therapy-Induced Senescence as a Model of Disease Recurrence after Dormancy

Abstract 459: Therapy-induced senescence is reversible in vitro and in vivo

Abstract 602: The α7 nicotinic acetylcholine receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy without enhancing the proliferation of lung cancer cells or interfering with paclitaxel-induced antitumor activity

Abstract 227: Mass spectrometry-based proteomics analysis of the non-small cell lung cancer secretome

Abstract 3299: Radiation induced p53-dependent cytoprotective autophagy fails to reduce radiation sensitivity in H460 non-small cell lung cancer cells

Abstract 986: Targeting nicotinic acetylcholine receptors for the prevention and reversal of chemotherapy-induced peripheral neuropathy

Abstract 5459: Autophagy and senescence as possible mechanisms leading to proliferative recovery and escape from treatment-induced tumor dormancy

Abstract 5470: Reversibility of therapy-induced senescence in non-small cell lung cancer as a model of cancer recurrence

The Challenge of Developing Autophagy Inhibition as a Therapeutic Strategy

Abstract 2846: Proliferative recovery after chemotherapy-induced senescence in non-small cell lung cancer (NSCLC) cells as a model of tumor dormancy and disease recurrence

Abstract 3574: Nicotine prevents chemotherapy-induced peripheral neuropathy in vivo, and fails to stimulate the growth of lung cancer cells or interfere with the effectiveness of chemotherapy in vitro

The Four Faces of Autophagy: Implications for Cancer Therapy

Abstract 5665: New alternatives to photodynamic therapy based on light-enabled drug delivery.

Abstract 1453: The cannabinoid Win55, 212-2 enhances the response of breast cancer cells to radiation

Abstract 1465: Radiosensitization of NSCLC through modulation of autophagy and senescence

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