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Davendra Sohal
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Journal Articles

Abstract 233: Cabozantinib changes the landscape of the pancreatic tumor microenvironment and improves the efficacy of pembrolizumab

Pritha Adhikary, Jayati Chakrabarti, Meenu Priya Resmi, Jiang Wang, Davendra Sohal, Rachna T. Shroff, Syed A. Ahmad, Yana Zavros
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 233.
https://doi.org/10.1158/1538-7445.AM2024-233
Published: 22 March 2024
View article titled, Abstract 233: Cabozantinib changes the landscape of the pancreatic tumor microenvironment and improves the efficacy of pembrolizumab
Journal Articles

Abstract 1582: Cabozantinib changes the tumor microenvironment to increase the efficacy of immunotherapy in refractory metastatic pancreatic ductal adenocarcinoma

Jayati Chakrabarti, Pritha Adhikary, Jiang Wang, Davendra Sohal, Syed A. Ahmad, Junaid Arshad, Aaron J. Scott, Rachna T. Shroff, Yana Zavros
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1582.
https://doi.org/10.1158/1538-7445.AM2024-1582
Published: 22 March 2024
View article titled, Abstract 1582: Cabozantinib changes the tumor microenvironment to increase the efficacy of immunotherapy in refractory metastatic pancreatic ductal adenocarcinoma
Journal Articles

Abstract B111: Developing prognostic signatures (ep-Sigs) through epigenetic predictive markers in pancreatic ductal adenocarcinoma (PDA) – A pilot study based on The Cancer Genome Atlas (TCGA) data

Ashish Manne, Wancai Yang, Davendra Sohal, Ashwini Esnakula, Lianbo Yu
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): B111.
https://doi.org/10.1158/1538-7445.PANCA2023-B111
Published: 16 January 2024
View article titled, Abstract B111: Developing prognostic signatures (ep-Sigs) through epigenetic predictive markers in pancreatic ductal adenocarcinoma (PDA) – A pilot study based on The Cancer Genome Atlas (TCGA) data
Journal Articles

Abstract 1088: Advancing non-cytotoxic DNMT1-targeting to treat chemorefractory pancreatic cancer

Rita Tohme, Francis Enane, Caroline Schuerger, Xiaorong Gu, Melissa Fishel, John Pink, Daniel Lindner, Davendra Sohal, Yogen Saunthararajah
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1088.
https://doi.org/10.1158/1538-7445.AM2021-1088
Published: 01 July 2021
View article titled, Abstract 1088: Advancing non-cytotoxic DNMT1-targeting to treat chemorefractory pancreatic cancer
Journal Articles

Abstract 3638: Analysis of the clinical benefit of comprehensive genome profiling derived therapeutic associations in advanced cancer

Jean Rene Clemenceau, Sung Hak Lee, Alex Milinovich, Jian Jin, Nathan Pennell, Davendra Sohal, Tae Hyun Hwang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3638.
https://doi.org/10.1158/1538-7445.AM2020-3638
Published: 15 August 2020
View article titled, Abstract 3638: Analysis of the clinical benefit of comprehensive genome profiling derived therapeutic associations in advanced cancer
Journal Articles

Abstract C58: p53/p16-independent cytoreduction of chemoresistant pancreatic adenocarcinoma by metabolically optimized epigenetic therapy

Rita Tohme, Xiaorong Gu, Asmaa El Desoky, Caroline Schuerger, Daniel Lindner, Davendra Sohal, Yogen Saunthararajah
Journal: Cancer Research
Cancer Res (2019) 79 (24_Supplement): C58.
https://doi.org/10.1158/1538-7445.PANCA19-C58
Published: 13 December 2019
View article titled, Abstract C58: p53/p16-independent cytoreduction of chemoresistant pancreatic adenocarcinoma by metabolically optimized epigenetic therapy
Journal Articles

Epigenetically Aberrant Stroma in MDS Propagates Disease via Wnt/β-Catenin Activation

Tushar D. Bhagat, Si Chen, Matthias Bartenstein, A. Trevor Barlowe, Dagny Von Ahrens, Gaurav S. Choudhary, Patrick Tivnan, Elianna Amin, A. Mario Marcondes, Mathijs A. Sanders, Remco M. Hoogenboezem, Suman Kambhampati, Nandini Ramachandra, Iaonnis Mantzaris, Vineeth Sukrithan, Remi Laurence, Robert Lopez, Prafulla Bhagat, Orsi Giricz, Davendra Sohal, Amittha Wickrema, Cecilia Yeung, Kira Gritsman, Peter Aplan, Konrad Hochedlinger, Yiting Yu, Kith Pradhan, Jinghang Zhang, John M. Greally, Siddhartha Mukherjee, Andrea Pellagatti, Jacqueline Boultwood, Britta Will, Ulrich Steidl, Marc H.G.P. Raaijmakers, H. Joachim Deeg, Michael G. Kharas, Amit Verma
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (18): 4846–4857.
https://doi.org/10.1158/0008-5472.CAN-17-0282
Published: 14 September 2017
View article titled, Epigenetically Aberrant Stroma in MDS Propagates Disease via Wnt/β-Catenin Activation
Open the PDF for Epigenetically Aberrant Stroma in MDS Propagates Disease via Wnt/β-Catenin Activation in another window
Includes: Supplementary data
Journal Articles

Abstract 1504: Pancreatic cancer associated fibroblasts are characterized by widespread epigenetic reprogramming that leads to aberrant expression of druggable target CXCR4.

Tushar D. Bhagat, Yanique Rattigan, Brijesh Patel, Strepell Mirte, Yiting Yu, Davendra Sohal, Matthias Bartenstein, Orsolya Giricz, Shanisha AK Gordon, Nishanth Vallumsetla, Rahul Polineni, Meher Walia, Paraic Kenny, John Greally, Debabrata Banerjee, Anirban Maitra, Amit Verma
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1504.
https://doi.org/10.1158/1538-7445.AM2013-1504
Published: 15 April 2013
View article titled, Abstract 1504: Pancreatic cancer associated fibroblasts are characterized by widespread epigenetic reprogramming that leads to aberrant expression of druggable target CXCR4.
Journal Articles

Abstract 1503: Myelodysplasia bone marrow stromal cells have widespread aberrant hypermethylation that is targeted by treatment with DNMT inhibitors.

Tushar D. Bhagat, Matthias Bartenstein, Yiting Yu, A. Mario Marcondes, Davendra Sohal, John Greally, H Joachim Deeg, Amit Verma
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1503.
https://doi.org/10.1158/1538-7445.AM2013-1503
Published: 15 April 2013
View article titled, Abstract 1503: Myelodysplasia bone marrow stromal cells have widespread aberrant hypermethylation that is targeted by treatment with DNMT inhibitors.
Journal Articles

Methylome Profiling Reveals Distinct Alterations in Phenotypic and Mutational Subgroups of Myeloproliferative Neoplasms

Sangeeta Nischal, Sanchari Bhattacharyya, Maximilian Christopeit, Yiting Yu, Li Zhou, Tushar D. Bhagat, Davendra Sohal, Britta Will, Yongkai Mo, Masako Suzuki, Animesh Pardanani, Michael McDevitt, Jaroslaw P. Maciejewski, Ari M. Melnick, John M. Greally, Ulrich Steidl, Alison Moliterno, Amit Verma
Journal: Cancer Research
Cancer Res (2013) 73 (3): 1076–1085.
https://doi.org/10.1158/0008-5472.CAN-12-0735
Published: 31 January 2013
View article titled, Methylome Profiling Reveals Distinct Alterations in Phenotypic and Mutational Subgroups of Myeloproliferative Neoplasms
Open the PDF for Methylome Profiling Reveals Distinct Alterations in Phenotypic and Mutational Subgroups of Myeloproliferative Neoplasms in another window
Includes: Supplementary data
Journal Articles

Reduced SMAD7 Leads to Overactivation of TGF-β Signaling in MDS that Can Be Reversed by a Specific Inhibitor of TGF-β Receptor I Kinase

Li Zhou, Christine McMahon, Tushar Bhagat, Cristina Alencar, Yiting Yu, Melissa Fazzari, Davendra Sohal, Christoph Heuck, Krishna Gundabolu, Chun Ng, Yongkai Mo, Wa Shen, Amittha Wickrema, Guanghui Kong, Ellen Friedman, Lubomir Sokol, Giannis Mantzaris, Andrea Pellagatti, Jacqueline Boultwood, Leonidas C. Platanias, Ulrich Steidl, Lei Yan, Jonathan M. Yingling, Michael M. Lahn, Alan List, Markus Bitzer, Amit Verma
Journal: Cancer Research
Cancer Res (2011) 71 (3): 955–963.
https://doi.org/10.1158/0008-5472.CAN-10-2933
Published: 01 February 2011
View article titled, Reduced SMAD7 Leads to Overactivation of TGF-β Signaling in MDS that Can Be Reversed by a Specific Inhibitor of TGF-β Receptor I Kinase
Open the PDF for Reduced SMAD7 Leads to Overactivation of TGF-β Signaling in MDS that Can Be Reversed by a Specific Inhibitor of TGF-β Receptor I Kinase in another window
Journal Articles

High resolution epigenomic analysis of melanoma reveals that combination of aberrant DNA methylation and gene copy number alterations can contribute to oncogenesis.

Yongkai Mo, Kathy Amiri, Mark Kelley, Davendra Sohal, Li Zhou, Tushar Bhagat, Perry Pahanish, Maria Figueroa, Kenny Ye, Reid Thomas, Ari Melnick, John Greally, Jeffrey Sosman, Amit Verma
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): LB-251.
Published: 01 May 2008
View article titled, High resolution epigenomic analysis of melanoma reveals that combination of aberrant DNA methylation and gene copy number alterations can contribute to oncogenesis.