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Journal Articles

Abstract 1877: Tripokin: potential best-in-class for tumor targeted interleukin-2 (IL2) potentiated by tumor necrosis factor (TNF)

Eleonora Prodi, Riccardo Corbellari, Mattia Matasci, Dario Neri, Roberto De Luca

Cancer Res (2023) 83 (7_Supplement): 1877.

https://doi.org/10.1158/1538-7445.AM2023-1877

Published: 04 April 2023

View article titled, Abstract 1877: Tripokin: potential best-in-class for tumor targeted interleukin-2 (IL2) potentiated by tumor necrosis factor (TNF)

Journal Articles

Abstract 5744: Decreasing toxicity of immunocytokines by transient and selective inhibition of their intracellular signaling activation

Giulia Rotta, Ettore Gilardoni, Domenico Ravazza, Jacqueline Mock, Samuele Cazzamalli, Roberto De Luca, Emanuele Puca, Dario Neri, Sheila Dakhel Plaza

Cancer Res (2023) 83 (7_Supplement): 5744.

https://doi.org/10.1158/1538-7445.AM2023-5744

Published: 04 April 2023

View article titled, Abstract 5744: Decreasing toxicity of immunocytokines by transient and selective inhibition of their intracellular signaling activation

Journal Articles

Abstract 1989: DNA-encoded affinity maturation libraries enable the discovery of low picomolar fibroblast activation protein inhibitors suitable for radioligand therapy of solid tumors

Sara Puglioli, Luca Prati, Sebastian Oehler, Andrea Galbiati, Dario Neri, Samuele Cazzamalli, Gabriele Bassi, Nicholas Favalli

Cancer Res (2023) 83 (7_Supplement): 1989.

https://doi.org/10.1158/1538-7445.AM2023-1989

Published: 04 April 2023

View article titled, Abstract 1989: DNA-encoded affinity maturation libraries enable the discovery of low picomolar fibroblast activation protein inhibitors suitable for radioligand therapy of solid tumors

Journal Articles

Abstract 1988: FAP-targeted non-internalising drug conjugates: A comparative evaluation between small molecules, antibodies and peptides

Aureliano Zana, Claudia Puig Moreno, Ettore Gilardoni, Dario Neri, Samuele Cazzamalli

Cancer Res (2023) 83 (7_Supplement): 1988.

https://doi.org/10.1158/1538-7445.AM2023-1988

Published: 04 April 2023

View article titled, Abstract 1988: FAP-targeted non-internalising drug conjugates: A comparative evaluation between small molecules, antibodies and peptides

Journal Articles

Abstract 1987: Delivery of potent cytotoxic camptothecin derivatives to tumors by OncoFAP-based small molecule-drug conjugates

Matilde Bocci, Samuele Cazzamalli, Dario Neri, Andrea Galbiati

Cancer Res (2023) 83 (7_Supplement): 1987.

https://doi.org/10.1158/1538-7445.AM2023-1987

Published: 04 April 2023

View article titled, Abstract 1987: Delivery of potent cytotoxic camptothecin derivatives to tumors by OncoFAP-based small molecule-drug conjugates

Journal Articles

Abstract 2838: Tumor-targeted interleukin-2 enhances the anti-cancer activity of multivalent OncoFAP radioligand therapeutics

Andrea Galbiati, Matilde Bocci, Ettore Gilardoni, Aureliano Zana, Dario Neri, Samuele Cazzamalli

Cancer Res (2023) 83 (7_Supplement): 2838.

https://doi.org/10.1158/1538-7445.AM2023-2838

Published: 04 April 2023

View article titled, Abstract 2838: Tumor-targeted interleukin-2 enhances the anti-cancer activity of multivalent OncoFAP radioligand therapeutics

Journal Articles

Abstract LB522: Fibroblast activation protein triggers the release of drug payload from non-internalizing small molecule-drug conjugates in solid tumors

Aureliano Zana, Andrea Galbiati, Ettore Gilardoni, Jacopo Millul, Theo Sturm, Riccardo Stucchi, Matilde Bocci, Abdullah Elsayed, Lisa Nadal, Martina Cirillo, Dario Neri, Samuele Cazzamalli

Cancer Res (2022) 82 (12_Supplement): LB522.

https://doi.org/10.1158/1538-7445.AM2022-LB522

Published: 15 June 2022

View article titled, Abstract LB522: Fibroblast activation protein triggers the release of drug payload from non-internalizing small molecule-drug conjugates in solid tumors

Journal Articles

Abstract LB527: A novel dimeric small molecule-radio conjugate targeting fibroblast activation protein with high and prolonged tumor uptake

Samuele Cazzamalli, Andrea Galbiati, Aureliano Zana, Matilde Bocci, Jacopo Millul, Jacqueline Mock, Abdullah Elsayed, Dario Neri

Cancer Res (2022) 82 (12_Supplement): LB527.

https://doi.org/10.1158/1538-7445.AM2022-LB527

Published: 15 June 2022

View article titled, Abstract LB527: A novel dimeric small molecule-radio conjugate targeting fibroblast activation protein with high and prolonged tumor uptake

Journal Articles

Abstract LB535: A novel IL12-based immunocytokine targeting fibroblast activation protein (FAP) for the treatment of cancer

Lisa Nadal, Frederik Peissert, Abdullah Elsayed, Chiara Libbra, Dario Neri, Roberto De Luca

Cancer Res (2022) 82 (12_Supplement): LB535.

https://doi.org/10.1158/1538-7445.AM2022-LB535

Published: 15 June 2022

View article titled, Abstract LB535: A novel IL12-based immunocytokine targeting fibroblast activation protein (FAP) for the treatment of cancer

Journal Articles

Abstract 2768: Potentiating the action of antibody-dependent cell-mediated cytotoxicity with immunocytokines

Patrizia Murer, Jonathan D. Kiefer, Louis Plüss, Dario Neri

Cancer Res (2018) 78 (13_Supplement): 2768.

https://doi.org/10.1158/1538-7445.AM2018-2768

Published: 01 July 2018

View article titled, Abstract 2768: Potentiating the action of antibody-dependent cell-mediated cytotoxicity with immunocytokines

Journal Articles

Abstract 5553: A novel immunocytokine for the treatment of cancer

Mattia Matasci, Emanuele Puca, Tiziano Ongaro, Sarah Wulhfard, Alessandra Villa, Dario Neri

Cancer Res (2018) 78 (13_Supplement): 5553.

https://doi.org/10.1158/1538-7445.AM2018-5553

Published: 01 July 2018

View article titled, Abstract 5553: A novel immunocytokine for the treatment of cancer

Journal Articles

Abstract 5563: Kinetically-controlled release of blocking molecules for the targeted enhancement of therapeutic activity in antibody-cytokine fusion proteins

Tiziano Ongaro, Martina Bigatti, Filippo Sladojevich, Etienne Donckele, Alessandra Micaela Villa, Dario Neri

Cancer Res (2018) 78 (13_Supplement): 5563.

https://doi.org/10.1158/1538-7445.AM2018-5563

Published: 01 July 2018

View article titled, Abstract 5563: Kinetically-controlled release of blocking molecules for the targeted enhancement of therapeutic activity in antibody-cytokine fusion proteins

Journal Articles

Abstract 3811: Targeted Interleukin 2 and synergy with immune check-point inhibitors

Cornelia Deborah Hutmacher-Berndt, Dario Neri

Cancer Res (2018) 78 (13_Supplement): 3811.

https://doi.org/10.1158/1538-7445.AM2018-3811

Published: 01 July 2018

View article titled, Abstract 3811: Targeted Interleukin 2 and synergy with immune check-point inhibitors

Journal Articles

Abstract 2785: Potency-matched dual cytokine antibody fusion proteins in combination with PD-L1 blockade

Roberto De Luca, Dario Neri

Cancer Res (2018) 78 (13_Supplement): 2785.

https://doi.org/10.1158/1538-7445.AM2018-2785

Published: 01 July 2018

View article titled, Abstract 2785: Potency-matched dual cytokine antibody fusion proteins in combination with PD-L1 blockade

Journal Articles

Abstract 758: Head-to-head comparison of ADC and SMDC products, alone and in combination with antibody-IL2 fusion proteins

Samuele Cazzamalli, Alberto Dal Corso, Fontaine Widmayer, Dario Neri

Cancer Res (2018) 78 (13_Supplement): 758.

https://doi.org/10.1158/1538-7445.AM2018-758

Published: 01 July 2018

View article titled, Abstract 758: Head-to-head comparison of ADC and SMDC products, alone and in combination with antibody-IL2 fusion proteins

Journal Articles

Sarcoma Eradication by Doxorubicin and Targeted TNF Relies upon CD8⁺ T-cell Recognition of a Retroviral Antigen

Philipp Probst, Janine Kopp, Annette Oxenius, Mario P. Colombo, Danilo Ritz, Tim Fugmann, Dario Neri

Cancer Res (2017) 77 (13): 3644–3654.

https://doi.org/10.1158/0008-5472.CAN-16-2946

Published: 02 July 2017

View article titled, Sarcoma Eradication by Doxorubicin and Targeted TNF Relies upon CD8<sup>+</sup> T-cell Recognition of a Retroviral Antigen

Includes: Supplementary data

Journal Articles

Abstract 589: Targeting of metastatic osteosarcoma with F8-TNF-alpha in an orthotopic mouse model

Bernhard Robl, Sander Martijn Botter, Aleksandar Boro, Dario Neri, Bruno Fuchs

Cancer Res (2016) 76 (14_Supplement): 589.

https://doi.org/10.1158/1538-7445.AM2016-589

Published: 15 July 2016

View article titled, Abstract 589: Targeting of metastatic osteosarcoma with F8-TNF-alpha in an orthotopic mouse model

Journal Articles

Abstract SY35-04: Arming tumor-targeting antibodies with cytokine payloads: Emerging clinical results

Dario Neri

Cancer Res (2015) 75 (15_Supplement): SY35-04.

https://doi.org/10.1158/1538-7445.AM2015-SY35-04

Published: 01 August 2015

View article titled, Abstract SY35-04: Arming tumor-targeting antibodies with cytokine payloads: Emerging clinical results

Journal Articles

Curative Properties of Noninternalizing Antibody–Drug Conjugates Based on Maytansinoids

Elena Perrino, Martina Steiner, Nikolaus Krall, Gonçalo J.L. Bernardes, Francesca Pretto, Giulio Casi, Dario Neri

Cancer Res (2014) 74 (9): 2569–2578.

https://doi.org/10.1158/0008-5472.CAN-13-2990

Published: 30 April 2014

View article titled, Curative Properties of Noninternalizing Antibody–Drug Conjugates Based on Maytansinoids

Includes: Supplementary data

Journal Articles

Abstract SY28-04: Targeting the tumor extracellular matrix with armed antibodies

Dario Neri

Cancer Res (2012) 72 (8_Supplement): SY28-04.

https://doi.org/10.1158/1538-7445.AM2012-SY28-04

Published: 15 April 2012

View article titled, Abstract SY28-04: Targeting the tumor extracellular matrix with armed antibodies

NARROW

Abstract 1877: Tripokin: potential best-in-class for tumor targeted interleukin-2 (IL2) potentiated by tumor necrosis factor (TNF)

Abstract 5744: Decreasing toxicity of immunocytokines by transient and selective inhibition of their intracellular signaling activation

Abstract 1989: DNA-encoded affinity maturation libraries enable the discovery of low picomolar fibroblast activation protein inhibitors suitable for radioligand therapy of solid tumors

Abstract 1988: FAP-targeted non-internalising drug conjugates: A comparative evaluation between small molecules, antibodies and peptides

Abstract 1987: Delivery of potent cytotoxic camptothecin derivatives to tumors by OncoFAP-based small molecule-drug conjugates

Abstract 2838: Tumor-targeted interleukin-2 enhances the anti-cancer activity of multivalent OncoFAP radioligand therapeutics

Abstract LB522: Fibroblast activation protein triggers the release of drug payload from non-internalizing small molecule-drug conjugates in solid tumors

Abstract LB527: A novel dimeric small molecule-radio conjugate targeting fibroblast activation protein with high and prolonged tumor uptake

Abstract LB535: A novel IL12-based immunocytokine targeting fibroblast activation protein (FAP) for the treatment of cancer

Abstract 2768: Potentiating the action of antibody-dependent cell-mediated cytotoxicity with immunocytokines

Abstract 5553: A novel immunocytokine for the treatment of cancer

Abstract 5563: Kinetically-controlled release of blocking molecules for the targeted enhancement of therapeutic activity in antibody-cytokine fusion proteins

Abstract 3811: Targeted Interleukin 2 and synergy with immune check-point inhibitors

Abstract 2785: Potency-matched dual cytokine antibody fusion proteins in combination with PD-L1 blockade

Abstract 758: Head-to-head comparison of ADC and SMDC products, alone and in combination with antibody-IL2 fusion proteins

Sarcoma Eradication by Doxorubicin and Targeted TNF Relies upon CD8⁺ T-cell Recognition of a Retroviral Antigen

Abstract 589: Targeting of metastatic osteosarcoma with F8-TNF-alpha in an orthotopic mouse model

Abstract SY35-04: Arming tumor-targeting antibodies with cytokine payloads: Emerging clinical results

Curative Properties of Noninternalizing Antibody–Drug Conjugates Based on Maytansinoids

Abstract SY28-04: Targeting the tumor extracellular matrix with armed antibodies

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