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Abstract A47: Inhibition of histone methyltransferase with novel epipolythiodioxopiperazines (ETP) alkaloids in pediatric high-grade glioma

Stephen Dombrowski, Thamara Abou-Antoun, Anthony Mansour, Rewa Arar, Mohammad Movassaghi, Erin Murphy, Shuvojit Banerjee, Xiao-Nan Li, Peter Houghton, Darell Bigner, Angel Montero Carcaboso, Jeremy Rich, Violette Recinos

Cancer Res (2018) 78 (19_Supplement): A47.

https://doi.org/10.1158/1538-7445.PEDCA17-A47

Published: 01 October 2018

View articletitled, Abstract A47: Inhibition of histone methyltransferase with novel epipolythiodioxopiperazines (ETP) alkaloids in pediatric high-grade glioma

Journal Articles

Abstract LB-302: Oncolytic poliovirus-mediated inflammation and immunity in breast cancer

Karenia Landa, Eda Holl, Michael Brown, James Herndon, Lars Grimm, Jeremy Force, Darell Bigner, Shelley Hwang, Matthias Gromeier, Smita Nair

Cancer Res (2018) 78 (13_Supplement): LB-302.

https://doi.org/10.1158/1538-7445.AM2018-LB-302

Published: 01 July 2018

View articletitled, Abstract LB-302: Oncolytic poliovirus-mediated inflammation and immunity in breast cancer

Journal Articles

Abstract 4417: Characterization of xenograft-derived EGFRvIII-positive GBM cell cultures reveals functional interactions between EGFRvIII, wild-type EGFR, and p53

Irwin Liu, Stephen Keir, B. Ahmed Rasheed, Darell Bigner

Cancer Res (2011) 71 (8_Supplement): 4417.

https://doi.org/10.1158/1538-7445.AM2011-4417

Published: 15 April 2011

View articletitled, Abstract 4417: Characterization of xenograft-derived EGFRvIII-positive GBM cell cultures reveals functional interactions between EGFRvIII, wild-type EGFR, and p53

Journal Articles

Sample Type Bias in the Analysis of Cancer Genomes

David A. Solomon, Jung-Sik Kim, Habtom W. Ressom, Zita Sibenaller, Timothy Ryken, Walter Jean, Darell Bigner, Hai Yan, Todd Waldman

Cancer Res (2009) 69 (14): 5630–5633.

https://doi.org/10.1158/0008-5472.CAN-09-1055

Published: 15 July 2009

View articletitled, Sample Type Bias in the Analysis of Cancer Genomes

Includes: Supplementary data

Journal Articles

Abstract #458: Decoupling of DNA damage response signaling from DNA methylation damages in temozolomide-resistant glioblastoma cells

Bo Cui, Stewart Johnson, Nancy Bullock, Francis Ali-Osman, Darell Bigner, Henry Friedman

Cancer Res (2009) 69 (9_Supplement): 458.

Published: 01 May 2009

View articletitled, Abstract #458: Decoupling of DNA damage response signaling from DNA methylation damages in temozolomide-resistant glioblastoma cells

Journal Articles

Abstract #1254: Podoplanin is a novel antibody-based therapeutic target for glioblastoma

Yukinari Kato, Kazuhiko Mishima, Mika Kaneko, Michael Zalutsky, Chien-Tsun Kuan, Darell Bigner

Cancer Res (2009) 69 (9_Supplement): 1254.

Published: 01 May 2009

View articletitled, Abstract #1254: Podoplanin is a novel antibody-based therapeutic target for glioblastoma

Journal Articles

Mutational Inactivation of PTPRD in Glioblastoma Multiforme and Malignant Melanoma

David A. Solomon, Jung-Sik Kim, Julia C. Cronin, Zita Sibenaller, Timothy Ryken, Steven A. Rosenberg, Habtom Ressom, Walter Jean, Darell Bigner, Hai Yan, Yardena Samuels, Todd Waldman

Cancer Res (2008) 68 (24): 10300–10306.

https://doi.org/10.1158/0008-5472.CAN-08-3272

Published: 15 December 2008

View articletitled, Mutational Inactivation of PTPRD in Glioblastoma Multiforme and Malignant Melanoma

Includes: Supplementary data

Journal Articles

Dual specific antibody, scds-D2C7-PE38KDEL, for GBM therapy

Vidyalakshmi Chandramohan, Charles Pegram, Scott Szafranski, Darell Bigner, Chien-Tsun Kuan

Cancer Res (2008) 68 (9_Supplement): 4053.

Published: 01 May 2008

View articletitled, Dual specific antibody, scds-D2C7-PE38KDEL, for GBM therapy

Journal Articles

Identification of p18^INK4c as a tumor suppressor gene in glioblastoma multiforme

David Solomon, Jung-Sik Kim, Sultan Jenkins, Habtom Ressom, Michael Huang, Darell Bigner, Hai Yan, Walter Jean, Todd Waldman

Cancer Res (2008) 68 (9_Supplement): 1708.

Published: 01 May 2008

View articletitled, Identification of p18INK4c as a tumor suppressor gene in glioblastoma multiforme

Journal Articles

Lack of DNA damage signalling underlies temozolomide resistance in a human glioblastoma multiforme cell line

Bo Cui, Bo Cui, Stewart Johnson, Nancy Bullock, Krystle Horne, Francis Ali-Osman, Darell Bigner, Henry Friedman

Cancer Res (2008) 68 (9_Supplement): 665.

Published: 01 May 2008

View articletitled, Lack of DNA damage signalling underlies temozolomide resistance in a human glioblastoma multiforme cell line

Journal Articles

Efficacy and immunologic effects of RNA-pulsed dendritic cell vaccines targeting human cytomegalovirus antigens in patients with glioblastoma

Duane Mitchell, Gary Archer, Darell Bigner, Annick Desjardins, Allan Friedman, Henry Friedman, Denise Lally-Goss, James Herndon, II, Sharon McGehee, Roger McLendon, Beth Perry, David Reardon, Jeremy Rich, Steve Silverman, James Vrendenburgh, John Sampson

Cancer Res (2008) 68 (9_Supplement): LB-73.

Published: 01 May 2008

View articletitled, Efficacy and immunologic effects of RNA-pulsed dendritic cell vaccines targeting human cytomegalovirus antigens in patients with glioblastoma

Journal Articles

Humoral and cell mediated responses to the EGFRvIII-targeted vaccine (CDX-110) are enhanced with continuous temozolomide in patients with GBM.

Gary Archer, Amy Heimberger, Darell Bigner, Tom Davis, Allan Friedman, Henry Friedman, Tibor Keler, Duane Mitchell, David Reardon, Raymond Sawaya, James Vredenberg, John Sampson

Cancer Res (2008) 68 (9_Supplement): LB-310.

Published: 01 May 2008

View articletitled, Humoral and cell mediated responses to the EGFRvIII-targeted vaccine (CDX-110) are enhanced with continuous temozolomide in patients with GBM.

Journal Articles

Selection of a recombinant scFv against MRP3 for GBM therapy

Nidhi Srivastava, Chien-Tsun Kuan, Darell Bigner, Wayne Marasco

Cancer Res (2008) 68 (9_Supplement): 2399.

Published: 01 May 2008

View articletitled, Selection of a recombinant scFv against MRP3 for GBM therapy

Journal Articles

Identification of p18^INK4c as a Tumor Suppressor Gene in Glioblastoma Multiforme

David A. Solomon, Jung-Sik Kim, Sultan Jenkins, Habtom Ressom, Michael Huang, Nicholas Coppa, Lauren Mabanta, Darell Bigner, Hai Yan, Walter Jean, Todd Waldman

Cancer Res (2008) 68 (8): 2564–2569.

https://doi.org/10.1158/0008-5472.CAN-07-6388

Published: 15 April 2008

View articletitled, Identification of p18INK4c as a Tumor Suppressor Gene in Glioblastoma Multiforme

Includes: Supplementary data

Journal Articles

The Kruppel-like factor 4 (KLF4) tumor suppressor gene is silenced by genetic and epigenetic mechanisms in medulloblastoma

Yukiko Nakahara, Paul Northcott, Paul Kongkham, John Peacock, Lars Feuk, Wiesia Grajkowska, Boleslaw Lach, Richard Grundy, Yancey Gillespie, Carlos Carlotti, Jr., Frederick Boop, Darell Bigner, Ian Pollack, Ronald Hamilton, Richard Gilbertson, Steven Scherer, James Rutka, Michael Taylor

Cancer Res (2007) 67 (9_Supplement): 1142.

Published: 01 May 2007

View articletitled, The Kruppel-like factor 4 (KLF4) tumor suppressor gene is silenced by genetic and epigenetic mechanisms in medulloblastoma

Journal Articles

The chloroethylnitrosourea, BCNU, activates the ATR-Chk1 pathway in medulloblastomas independent of the DNA mismatch repair pathway

Bo Cui, Stewart Johnson, Francis Ali-Osman, Darell Bigner, Henry Friedman

Cancer Res (2007) 67 (9_Supplement): 1069.

Published: 01 May 2007

View articletitled, The chloroethylnitrosourea, BCNU, activates the ATR-Chk1 pathway in medulloblastomas independent of the DNA mismatch repair pathway

Journal Articles

High-resolution copy number analysis identifies novel tumor suppressor genes and pathways in medulloblastoma

Paul Northcott, Yukiko Nakahara, Paul Kongkham, John Peacock, Lars Feuk, Sunil Rao, Wiesia Grajkowska, Boleslaw Lach, Richard Grundy, Yancey Gillespie, Carlos Carlotti, Frederick Boop, Darell Bigner, Ian Pollack, Ronald Hamilton, Richard Gilbertson, Steven Scherer, James Rutka, Michael Taylor

Cancer Res (2007) 67 (9_Supplement): 621.

Published: 01 May 2007

View articletitled, High-resolution copy number analysis identifies novel tumor suppressor genes and pathways in medulloblastoma

Journal Articles

Mechanisms of Temozolomide resistance in pediatric glioblastoma multiforme

Daniel Wu, Bo Cui, Stewart Johnson, Stephen Keir, Jill Maxwell, Darell Bigner, Henry Friedman

Cancer Res (2007) 67 (9_Supplement): LB-324.

Published: 01 May 2007

View articletitled, Mechanisms of Temozolomide resistance in pediatric glioblastoma multiforme

Journal Articles

Identification of novel medulloblastoma oncogenes and tumor suppressor genes through high resolution SNP genotyping.

Paul A. Northcott, Yukiko Nakahara, Paul Kongkham, Stephen Scherer, Wiesia Grajkowska, Yancey Gillespie, Darell Bigner, Boleslaw Lach, Richard Gilbertson, James T. Rutka, Michael D. Taylor

Cancer Res (2006) 66 (8_Supplement): 1337.

Published: 15 April 2006

View articletitled, Identification of novel medulloblastoma oncogenes and tumor suppressor genes through high resolution SNP genotyping.

Journal Articles

Identification of methylation hotspots in the GSTP1 region associated with transcriptional silencing of the GSTP1 gene in human gliomas

Gamil Antoun, Pamela Gasdaska, Andrew Parker, Bartley Adams, Henry Friedman, Roger McLendon, Darell Bigner, Francis Ali-Osman

Cancer Res (2006) 66 (8_Supplement): 1–2.

Published: 15 April 2006

View articletitled, Identification of methylation hotspots in the GSTP1 region associated with transcriptional silencing of the GSTP1 gene in human gliomas

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Abstract A47: Inhibition of histone methyltransferase with novel epipolythiodioxopiperazines (ETP) alkaloids in pediatric high-grade glioma

Abstract LB-302: Oncolytic poliovirus-mediated inflammation and immunity in breast cancer

Abstract 4417: Characterization of xenograft-derived EGFRvIII-positive GBM cell cultures reveals functional interactions between EGFRvIII, wild-type EGFR, and p53

Sample Type Bias in the Analysis of Cancer Genomes

Abstract #458: Decoupling of DNA damage response signaling from DNA methylation damages in temozolomide-resistant glioblastoma cells

Abstract #1254: Podoplanin is a novel antibody-based therapeutic target for glioblastoma

Mutational Inactivation of PTPRD in Glioblastoma Multiforme and Malignant Melanoma

Dual specific antibody, scds-D2C7-PE38KDEL, for GBM therapy

Identification of p18^INK4c as a tumor suppressor gene in glioblastoma multiforme

Lack of DNA damage signalling underlies temozolomide resistance in a human glioblastoma multiforme cell line

Efficacy and immunologic effects of RNA-pulsed dendritic cell vaccines targeting human cytomegalovirus antigens in patients with glioblastoma

Humoral and cell mediated responses to the EGFRvIII-targeted vaccine (CDX-110) are enhanced with continuous temozolomide in patients with GBM.

Selection of a recombinant scFv against MRP3 for GBM therapy

Identification of p18^INK4c as a Tumor Suppressor Gene in Glioblastoma Multiforme

The Kruppel-like factor 4 (KLF4) tumor suppressor gene is silenced by genetic and epigenetic mechanisms in medulloblastoma

The chloroethylnitrosourea, BCNU, activates the ATR-Chk1 pathway in medulloblastomas independent of the DNA mismatch repair pathway

High-resolution copy number analysis identifies novel tumor suppressor genes and pathways in medulloblastoma

Mechanisms of Temozolomide resistance in pediatric glioblastoma multiforme

Identification of novel medulloblastoma oncogenes and tumor suppressor genes through high resolution SNP genotyping.

Identification of methylation hotspots in the GSTP1 region associated with transcriptional silencing of the GSTP1 gene in human gliomas

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