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Darawalee Wangsa
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Journal Articles

Abstract 3890: Novel miFISH single-cell approach gives new insights into chromosomal instability and evolution of colorectal cancers

Free
Anna Roschke, Darawalee Wangsa, Nina Gutzeit, Richard Korshkov, Tim Thoerner, Kerstin Heselmeyer-Haddad, Paul Meltzer
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3890.
https://doi.org/10.1158/1538-7445.AM2025-3890
Published: 21 April 2025
View articletitled, Abstract 3890: Novel miFISH single-cell approach gives new insights into chromosomal instability and evolution of colorectal cancers
Journal Articles

Abstract 4360: Integrative analysis of multiplex interphase FISH copy number with whole exome sequencing identifies tumor evolution in Stage II colon cancer

Free
Sanam Yaghoubi, Kerstin Heselmeyer-Haddad, Ivan Archilla, Carolina Parra, Darawalee Wangsa, Giancarlo Castellano, Jack Zhu, Diba Yaghoubi, Sara Lahoz, Veronica Pablo-Fontecha3, Daniela Hirsch, Wei-Dong Chen, Thomas Ried, Miriam Cuatrecasas, Paul S. Meltzer, Jordi Camps
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4360.
https://doi.org/10.1158/1538-7445.AM2024-4360
Published: 22 March 2024
View articletitled, Abstract 4360: Integrative analysis of multiplex interphase FISH copy number with whole exome sequencing identifies tumor evolution in Stage II colon cancer
Journal Articles

Abstract 1099: Combined MEK and RET inhibition overcomes resistance to single agent RET inhibition in medullary thyroid cancer

Free
Arwa Fallatah, Abdelrahman Rahmy, Sophia Khan, Hsien-chao Chou, Kerstin Heselmeyer-Haddad, Darawalee Wangsa, David Milewski, Yong Kim, Robert Hawley, Young Song, Xiaohu Zhang, Craig Thomas, Jun S. Wei, Jong-In Park, John Glod, Javed Khan
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1099.
https://doi.org/10.1158/1538-7445.AM2024-1099
Published: 22 March 2024
View articletitled, Abstract 1099: Combined MEK and RET inhibition overcomes resistance to single agent RET inhibition in medullary thyroid cancer
Journal Articles

Extrachromosomal Amplification of Human Papillomavirus Episomes Is a Mechanism of Cervical Carcinogenesis

Available to Purchase
Nicole M. Rossi, Jieqiong Dai, Yi Xie, Darawalee Wangsa, Kerstin Heselmeyer-Haddad, Hong Lou, Joseph F. Boland, Meredith Yeager, Roberto Orozco, Enrique Alvirez Freites, Lisa Mirabello, Eduardo Gharzouzi, Michael Dean
Journal: Cancer Research
Cancer Res (2023) 83 (11): 1768–1781.
https://doi.org/10.1158/0008-5472.CAN-22-3030
Published: 02 June 2023
View articletitled, Extrachromosomal Amplification of Human Papillomavirus Episomes Is a Mechanism of Cervical Carcinogenesis
Open the PDF for Extrachromosomal Amplification of Human Papillomavirus Episomes Is a Mechanism of Cervical Carcinogenesis in another window
Includes: Supplementary data
Journal Articles

Abstract 314: Intratumor genetic heterogeneity dictates metastatic subclones in stage II colon cancer

Free
Sanam Yaghoubi, Kerstin Heselmeyer-Haddad, Ivan Archilla, Carolina Parra, Darawalee Wangsa, Giancarlo Castellano, Sara Lahoz, Veronica Pablo-Fontecha, Daniela Hirsch, Wei-Dong Chen, Thomas Ried, Miriam Cuatrecasas, Paul S. Meltzer, Jordi Camps
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 314.
https://doi.org/10.1158/1538-7445.AM2023-314
Published: 04 April 2023
View articletitled, Abstract 314: Intratumor genetic heterogeneity dictates metastatic subclones in stage II colon cancer
Journal Articles

Abstract 2153: ATR inhibition augments the efficacy of the lurbinectedin in small cell lung cancer

Free
Christopher William Schultz, Yang Zhang, Haiqing Fu, Yasuhisa Murai, Darawalee Wangsa, Devon Atkinson, Liton Saha, Brian Elenbaas, Chien-Fei Lee, Astrid Zimmerman, Thomas Ried, Frank Zenke, Zoe Weaver, Rajaa Elmeskini, Yves Pommier, Anish Thomas
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2153.
https://doi.org/10.1158/1538-7445.AM2022-2153
Published: 15 June 2022
View articletitled, Abstract 2153: ATR inhibition augments the efficacy of the lurbinectedin in small cell lung cancer
Journal Articles

Abstract 1169: Novel renal medullary carcinoma cell lines, UOK353 and UOK360, provide preclinical tools to identify new therapeutics

Free
Darmood Wei, Youfeng Yang, Christopher J. Ricketts, Cathy D. Vocke, Mark W. Ball, Carole Sourbier, Darawalee Wangsa, Danny Wangsa, Rajarshi Guha, Xiaohu Zhang, Paul Meltzer, Thomas Reid, Craig J. Thomas, Maria J. Merino, W. Marston Linehan
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1169.
https://doi.org/10.1158/1538-7445.AM2018-1169
Published: 01 July 2018
View articletitled, Abstract 1169: Novel renal medullary carcinoma cell lines, UOK353 and UOK360, provide preclinical tools to identify new therapeutics
Journal Articles

SMYD5 Controls Heterochromatin and Chromosome Integrity during Embryonic Stem Cell Differentiation

Available to Purchase
Benjamin L. Kidder, Runsheng He, Darawalee Wangsa, Hesed M. Padilla-Nash, M. Margarida Bernardo, Shijie Sheng, Thomas Ried, Keji Zhao
Journal: Cancer Research
Cancer Res (2017) 77 (23): 6729–6745.
https://doi.org/10.1158/0008-5472.CAN-17-0828
Published: 30 November 2017
View articletitled, SMYD5 Controls Heterochromatin and Chromosome Integrity during Embryonic Stem Cell Differentiation
Open the PDF for SMYD5 Controls Heterochromatin and Chromosome Integrity during Embryonic Stem Cell Differentiation in another window
Includes: Supplementary data
Journal Articles

ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer

Available to Purchase
Vivek Shukla, Mahadev Rao, Hongen Zhang, Jeanette Beers, Darawalee Wangsa, Danny Wangsa, Floryne O. Buishand, Yonghong Wang, Zhiya Yu, Holly S. Stevenson, Emily S. Reardon, Kaitlin C. McLoughlin, Andrew S. Kaufman, Eden C. Payabyab, Julie A. Hong, Mary Zhang, Sean Davis, Daniel Edelman, Guokai Chen, Markku M. Miettinen, Nicholas P. Restifo, Thomas Ried, Paul A. Meltzer, David S. Schrump
Journal: Cancer Research
Cancer Res (2017) 77 (22): 6267–6281.
https://doi.org/10.1158/0008-5472.CAN-17-0570
Published: 14 November 2017
View articletitled, ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer
Open the PDF for ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 3947: Intratumor heterogeneity impacts treatment response in rectal carcinoma

Free
Rüdiger Meyer, Nicole E. McNeil, Darawalee Wangsa, Lena Anthuber, Noam Auslander, Danny Wangsa, Zhongqiu Zhang, Daniel Rosenberg, Eytan Ruppin, Jens K. Habermann, Thomas Ried
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3947.
https://doi.org/10.1158/1538-7445.AM2017-3947
Published: 01 July 2017
View articletitled, Abstract 3947: Intratumor heterogeneity impacts treatment response in rectal carcinoma
Journal Articles

Abstract 4387: The clonal composition of colorectal cancer cell lines is defined by the maintenance of specific genomic imbalances, not by ongoing chromosomal instability

Free
Darawalee Wangsa, Madison Schiefer, Daniel Bronder, Hesed Padilla-Nash, Irianna Torres, Lidia Warner, Yue Hu, E Michael Gertz, Russell Schwartz, Alejandro A. Schäffer, Daniela Hirsch, Timo Gaiser, Rüdiger Meyer, Jordi Camps, Kerstin Heselmeyer-Haddad, Thomas Ried
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4387.
https://doi.org/10.1158/1538-7445.AM2017-4387
Published: 01 July 2017
View articletitled, Abstract 4387: The clonal composition of colorectal cancer cell lines is defined by the maintenance of specific genomic imbalances, not by ongoing chromosomal instability
Journal Articles

Abstract 1438: The dynamics of genetic aberrations in Crohn's disease associated colorectal carcinogenesis

Free
Daniela D. Hirsch, Darawalee Wangsa, Yue Hu, Jack Zhu, David Petersen, Daniel C. Edelman, Paul S. Meltzer, Bao Tran, Kerstin Heselmeyer-Haddad, Thomas Ried, Timo Gaiser
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1438.
https://doi.org/10.1158/1538-7445.AM2017-1438
Published: 01 July 2017
View articletitled, Abstract 1438: The dynamics of genetic aberrations in Crohn's disease associated colorectal carcinogenesis
Journal Articles

Abstract 1979: Comprehensive analysis of the dynamics of aberrant WNT signaling on global gene expression and higher order nuclear structure in human cells

Free
Markus Brown, Darawalee Wangsa, Yue Hu, Thomas Ried
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1979.
https://doi.org/10.1158/1538-7445.AM2016-1979
Published: 15 July 2016
View articletitled, Abstract 1979: Comprehensive analysis of the dynamics of aberrant WNT signaling on global gene expression and higher order nuclear structure in human cells
Journal Articles

Abstract 3031: Replication stress and DNA damage promote genomic instability in near-tetraploid colorectal cancer cells

Free
Isabel Quintanilla, Darawalee Wangsa, Markus Brown, Amaia Ercilla, Greg Klus, Maria Vila, Juan José Lozano, Zoltan Szallsi, Neus Agell, Antoni Castells, Thomas Ried, Jordi Camps
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3031.
https://doi.org/10.1158/1538-7445.AM2015-3031
Published: 01 August 2015
View articletitled, Abstract 3031: Replication stress and DNA damage promote genomic instability in near-tetraploid colorectal cancer cells
Journal Articles

Abstract 2182: Reconstructing evolutionary models of tumor progression from single-cell heterogeneity data

Free
Salim A. Chowdhury, E. Michael Gertz, Darawalee Wangsa, Kerstin Heselmeyer-Haddad, Thomas Ried, Alejandro Schaeffer, Russell Schwartz
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2182.
https://doi.org/10.1158/1538-7445.AM2015-2182
Published: 01 August 2015
View articletitled, Abstract 2182: Reconstructing evolutionary models of tumor progression from single-cell heterogeneity data
Journal Articles

Abstract 5338: Inferring evolutionary models of tumor progression from single-cell heterogeneity data

Free
Salim A. Chowdhury, Ayshwarya Subramanian, Alejandro A. Schäffer, Stanley E. Shackney, Darawalee Wangsa, Kerstin Heselmeyer-Haddad, Thomas Ried, Russell Schwartz
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5338.
https://doi.org/10.1158/1538-7445.AM2014-5338
Published: 01 October 2014
View articletitled, Abstract 5338: Inferring evolutionary models of tumor progression from single-cell heterogeneity data
Journal Articles

Abstract 2895: Phylogenetic models of tumor progression from fluorescence in situ hybridization (FISH) data on many single cells of a solid tumor.

Free
Salim A. Chowdhury, Alejandro A. Schäffer, Stanley E. Shackney, Darawalee Wangsa, Kerstin Heselmeyer-Haddad, Thomas Ried, Russell Schwartz
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2895.
https://doi.org/10.1158/1538-7445.AM2013-2895
Published: 15 April 2013
View articletitled, Abstract 2895: Phylogenetic models of tumor progression from fluorescence in situ hybridization (FISH) data on many single cells of a solid tumor.
Journal Articles

Abstract 333: FISH markers in oral tongue squamous cell carcinoma

Free
Darawalee Wangsa, Michael Ryott, Göran Elmberger, Alejandro A. Schäffer, Gert Auer, Elisabeth Åvall Lundqvist, Eva Munck-Wikland, Thomas Ried, Kerstin Heselmeyer-Haddad
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 333.
https://doi.org/10.1158/1538-7445.AM10-333
Published: 15 April 2010
View articletitled, Abstract 333: FISH markers in oral tongue squamous cell carcinoma