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Daniel Von Hoff
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Journal Articles

Abstract 3931: TGN-1062 inhibits CDK7 and augments the effects of gemcitabine and nab-paclitaxel in pancreatic cancer models

Alexis Weston, Trason Thode, Ryan Rodriguez del Villar, Serina Ng, Samuel Sampson, Shelby Rheinschmidt, Tithi Ghosh Halder, Raffaella Soldi, Mohan Kaadige, Srinivas Kasibhatla, Haiyong Han, Justin Moser, Vincent Chung, Joseph Chao, Victoria Villaflor, Daniel Von Hoff, Sunil Sharma
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3931.
DOI: https://doi.org/10.1158/1538-7445.AM2022-3931
Published: 15 June 2022
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Journal Articles

Abstract 3389: An exosomal miRNA-based liquid biopsy signature for the noninvasive early detection of pancreatic ductal adenocarcinoma

Kota Nakamura, Souvick Roy, Zhongxu Zhu, Eunsung Jun, Haiyong Han, Ruben M. Munoz, Satoshi Nishiwada, Geeta Sharma, Derek Cridebring, Frederic Zenhausern, Seungchan Kim, Denise Roe, Sourat Darabi, In Woong Han, Douglas Evans, Suguru Yamada, Michael Demure, Scott A. Celinski, Erkut Borazanci, Susan Tsai, John Bolton, Yasuhiro Kodera, Joon Oh Park, Song Cheol Kim, Xin Wang, Daniel Von Hoff, Ajay Goel
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3389.
DOI: https://doi.org/10.1158/1538-7445.AM2022-3389
Published: 15 June 2022
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Journal Articles

Abstract CT155: Role of Time intensity & density curve for detecting early changes in pancreatic adenocarcinoma

Syed Rahmanuddin, Derek Cridebring, Ron Korn, Jordyn Brase, Pejman Motarjem, Wenli Kai, Vincent Chung, Erkut Borazanci, Ajay Goel, Daniel Von Hoff
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT155.
DOI: https://doi.org/10.1158/1538-7445.AM2021-CT155
Published: 01 July 2021
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Abstract CT156: Radiologic scoring method to define the therapeutic response and surgical candidacy

Syed Rahmanuddin, Daniel Von Hoff, Derek Cridebring, Jordyn Brase, Yuman Fong, Pejman Motarjem, Ron Korn, Kevin Choong, William Boswell, Erkut Borazanci
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT156.
DOI: https://doi.org/10.1158/1538-7445.AM2021-CT156
Published: 01 July 2021
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Journal Articles

Abstract 1084: EpiPanGI-Dx: A cell-free DNA methylation fingerprint for the early detection of gastrointestinal cancers

Raju Kandimalla, Jianfeng Xu, Alexander Link, Takatoshi Matsuyama, Kensuke Yamamura, Iqbal Parker, Hiroyuki Uetake, Eva Hernandez-Illan, Juanjo Lozano, Erkut Borazanci, Susan Tsai, Douglas Evans, Stephen J. Meltzer, Hideo Baba, Randall Brand, Daniel Von Hoff, Francesc Balaguer, Wei Li, Ajay Goel
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1084.
DOI: https://doi.org/10.1158/1538-7445.AM2020-1084
Published: 15 August 2020
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Journal Articles

Abstract B05: Paclitaxel protein bound plus gemcitabine plus cisplatin and paricalcitol neoadjuvant therapy for localized pancreatic ductal adenocarcinoma (PDAC)

Erkut Borazanci, Gayle Jameson, Courtney Snyder, Frank Tsai, Michael Gordon, Sunil Sharma, Carol Guarnieri, Amar Thosani, Syed Rahmanuddin, Ronald Korn, Steven Sckolnik, Paula Sedivy, Susan Haag, Kevin Gosselin, Daniel Von Hoff, Albert Amini
Journal: Cancer Research
Cancer Res (2019) 79 (24_Supplement): B05.
DOI: https://doi.org/10.1158/1538-7445.PANCA19-B05
Published: 13 December 2019
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Journal Articles

Abstract 1622: Role of 3d volumetric and perfusion imaging for detecting early changes in pancreatic adenocarcinoma

Syed Rahmanuddin, Erkut Borazanci, Vincent Chung, Derek Cridebring, Ronald Korn, Joyce Ho, William Boswell, Daniel Von Hoff
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1622.
DOI: https://doi.org/10.1158/1538-7445.AM2019-1622
Published: 01 July 2019
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Journal Articles

Abstract CT014: Initial results from the Phase I study of MSC-1, a humanized anti-LIF monoclonal antibody, in patients with advanced solid tumors

Alison Schram, Anna Spreafico, Marc Oliva, Irene Brana, Elena Garralda, Nehal Lakhani, Daniel Von Hoff, Erkut Borazanci, Naimish Pandya, Kimberly Hoffman, Robin Hallett, Patricia Giblin, Judit Anido, Adrianne Kelly, Robert Wasserman, Joan Seoane, Lillian Siu, David M. Hyman, Josep Tabernero
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT014.
DOI: https://doi.org/10.1158/1538-7445.AM2019-CT014
Published: 01 July 2019
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Journal Articles

Abstract CT165: Phase II open label trial of minnelide™ in patients with chemotherapy refractory metastatic pancreatic cancer

David Propper, Haiyong Han, Daniel Von Hoff, Erkut Borazanci, Tannishtha Reya, Jonathan Ghergurovich, Irina Pshenichnaya, Corina Antal, Rachel Condjella, Shreya Sharma, Peter O'Dwyer, Trevor Littlewood, Hitendra Patel, Ashok Saluja, Mohana Velagapudi, Lifeng Yang, Michael Downes, Ronald Evans, Gerard Evan
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT165.
DOI: https://doi.org/10.1158/1538-7445.AM2019-CT165
Published: 01 July 2019
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Journal Articles

Abstract 5353: Single cell RNA sequencing of pancreatic ductal adenocarcinoma reveals tumor heterogeneity

Pawan Noel, Wei Lin, Erkut Borazanci, Albert Amini, Ruben Muñoz, Emily Rodela, Serina Ng, Daniel Von Hoff, Haiyong Han
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5353.
DOI: https://doi.org/10.1158/1538-7445.AM2018-5353
Published: 01 July 2018
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Journal Articles

Abstract 2978: Discrete super-enhancer networks in pancreatic cancer cells and cancer associated fibroblasts are targeted and modulated by triptolide

Pawan Noel, Serina Ng, Ruben Muñoz, Daniel Von Hoff, Haiyong Han
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2978.
DOI: https://doi.org/10.1158/1538-7445.AM2017-2978
Published: 01 July 2017
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Journal Articles

Abstract 2113: Mechanism of action of pixantrone in non-Hodgkin's lymphoma cells

Serina Ng, Ruben Muñoz, Daniel Von Hoff, Haiyong Han
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2113.
DOI: https://doi.org/10.1158/1538-7445.AM2017-2113
Published: 01 July 2017
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Journal Articles

Abstract CT024: First-in-human phase 1 dose-escalation study of DS-6051b, an oral ROS1 and NTRK inhibitor, in subjects with advanced solid tumors

Kyriakos P. Papadopoulos, Erkut Borazanci, Daniel Von Hoff, Leena Gandhi, Amita Patnaik, Masaya Tachibana, Hamim Zahir, Roohi Gajee, Terri Goldberg, Giorgio Senaldi, Sai-Hong Ou
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): CT024.
DOI: https://doi.org/10.1158/1538-7445.AM2016-CT024
Published: 15 July 2016
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Abstract 2399: Circulating tumor DNA (ctDNA) analysis of PIK3CA and AKT1 mutations in patients enrolled onto the Phase 1b study of the PI3K inhibitor taselisib (GDC-0032) in solid malignancies

Timothy R. Wilson, Heidi Savage, Junko Aimi, Jessica Jin, Hema Parmar, Jerry Hsu, Ian Krop, Cristina Saura, Andres Cervantes, Jasgit Sachdev, Manish Patel, Juan Cejalvo, Mafalda Oliveira, Eric Winer, Daniel Von Hoff, Jose Baselga, Dejan Juric
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2399.
DOI: https://doi.org/10.1158/1538-7445.AM2015-2399
Published: 01 August 2015
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Journal Articles

Abstract 5514: Pharmacokinetics of BIND-014 (docetaxel nanoparticles for injectable suspension) in preclinical species and patients with advanced solid tumors

Jason Summa, Daniel Von Hoff, Jasgit Sachdev, Monica Mita, Patricia LoRusso, Peter Eisenberg, Howard Burris, Lowell Hart, Hagop Youssoufian, Donald Parsons, Susan Low
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5514.
DOI: https://doi.org/10.1158/1538-7445.AM2015-5514
Published: 01 August 2015
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Journal Articles

Abstract CT203: Report of a first-in-human study of the first-in-class fatty acid synthase (FASN) inhibitor TVB-2640

Manish Patel, Jeffrey Infante, Daniel Von Hoff, Suzanne Jones, Howard Burris, Andrew Brenner, William McCulloch, Valentina Zhukova-Harrill, George Kemble, Merdad Parsey
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): CT203.
DOI: https://doi.org/10.1158/1538-7445.AM2015-CT203
Published: 01 August 2015
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Abstract CT207: Phase I dose escalation and pharmokinetic study of 14-O-phosphonooxymethyltriptolide

Edward Greeno, Erkut Borazanci, Jon Gockerman, Ronald Korn, Ashok Saluja, Daniel Von Hoff
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): CT207.
DOI: https://doi.org/10.1158/1538-7445.AM2015-CT207
Published: 01 August 2015
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Abstract 1475: Therapeutic responses in a novel patient-derived xenograft mouse model for rare acinar cell pancreatic carcinoma

Laura A. Marlow, Adam C. Mathias, Louis K. Dawson, William F. Durham, Kenneth A. Meshaw, Robert J. Mullin, Aidan J. Synnott, Ricardo Paz-Fumagalli, Murli Krishna, Daniel Von Hoff, Daniel L. Small, Gerardo Colon-Otero, John A. Copland
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1475.
DOI: https://doi.org/10.1158/1538-7445.AM2015-1475
Published: 01 August 2015
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Journal Articles

Abstract P1-07-05: Triple negative breast cancer metastases: Protein signal transduction networks within the tumor-stromal microenvironment complement genomic analysis and stratify local versus distant metastasis

Virginia Espina, Maren K Levin, John D Carpten, David W Craig, Daniel Von Hoff, Lance A Liotta, Joyce O'Shaughnessy
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P1-07-05.
DOI: https://doi.org/10.1158/1538-7445.SABCS14-P1-07-05
Published: 01 May 2015
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Abstract 1067: Somatic genomic mutations, RNA-Seq, and proteomic signal transduction network analysis of tumor and stroma in metastatic triple negative breast cancer

Virginia A. Espina, Joyce A. O'Shaughnessy, Maren K. Levin, David W. Craig, John D. Carpten, Daniel Von Hoff, Lance A. Liotta
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1067.
DOI: https://doi.org/10.1158/1538-7445.AM2014-1067
Published: 01 October 2014
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