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Journal Articles

Abstract 1140: Digital twins for in vivo metabolic flux estimations in brain cancer patients

Baharan Meghdadi, Wajd N. Al-Holou, Andrew J. Scott, Anjali Mittal, Ningning Liang, Sravya Palavalasa, Abhinav Achreja, Nathan Qi, Alexandra O'Brien, Vijay Tarnal, Weihua Zhou, Theodore S. Lawrence, Costas A. Lyssiotis, Daniel R. Wahl, Deepak Nagrath

Cancer Res (2025) 85 (8_Supplement_1): 1140.

https://doi.org/10.1158/1538-7445.AM2025-1140

Published: 21 April 2025

View articletitled, Abstract 1140: Digital twins for in vivo metabolic flux estimations in brain cancer patients

Journal Articles

Abstract 1789: Machine learning-based method to analyze metabolic fluxes of patient tumors

Baharan Meghdadi, Anjali Mittal, Andrew J. Scott, Sravya Palavalasa, Daniel R. Wahl, Deepak Nagrath

Cancer Res (2024) 84 (6_Supplement): 1789.

https://doi.org/10.1158/1538-7445.AM2024-1789

Published: 22 March 2024

View articletitled, Abstract 1789: Machine learning-based method to analyze metabolic fluxes of patient tumors

Journal Articles

Abstract 1801: Rewiring of cortical glucose metabolism fuels human brain cancer growth

Cancer Res (2024) 84 (6_Supplement): 1801.

https://doi.org/10.1158/1538-7445.AM2024-1801

Published: 22 March 2024

View articletitled, Abstract 1801: Rewiring of cortical glucose metabolism fuels human brain cancer growth

Journal Articles

Abstract A004: GTP signaling links metabolism, DNA repair, and responses to genotoxic stress

Cancer Res (2024) 84 (5_Supplement_1): A004.

https://doi.org/10.1158/1538-7445.BRAIN23-A004

Published: 04 March 2024

View articletitled, Abstract A004: GTP signaling links metabolism, DNA repair, and responses to genotoxic stress

Journal Articles

Abstract B045: Adaptive purine metabolism drives radiation therapy resistance in H3K27M-diffuse midline glioma

Erik R. Peterson, Peter Sajjakulnukit, Andrew Scott, Caleb Heaslip, Anthony Andren, Kari Wilder-Romans, Angelica Lin, Alexandra Obrien, Zitong Zhao, Li Zhang, Sriram Venneti, Carl Koschmann, Nada Jabado, Maria G. Castro, Daniel R. Wahl

Cancer Res (2024) 84 (5_Supplement_1): B045.

https://doi.org/10.1158/1538-7445.BRAIN23-B045

Published: 04 March 2024

View articletitled, Abstract B045: Adaptive purine metabolism drives radiation therapy resistance in H3K27M-diffuse midline glioma

Journal Articles

Abstract B051: DNA damage signaling activates GTP synthesis to promote glioblastoma treatment resistance

Andrew J. Scott, Alexandra O'Brien, Weihua Zhou, Jie Xu, Sravya Palavalasa, Ayesha U. Kothari, Kari Wilder-Romans, Li Zhang, Anthony C. Andren, Sriram Chandrasekaran, Jason Heth, Yoshie Umemura, Nathan Qi, Theodore S. Lawrence, Wajd N. Al-Holou, Costas A. Lyssiotis, Daniel R Wahl

Cancer Res (2024) 84 (5_Supplement_1): B051.

https://doi.org/10.1158/1538-7445.BRAIN23-B051

Published: 04 March 2024

View articletitled, Abstract B051: DNA damage signaling activates GTP synthesis to promote glioblastoma treatment resistance

Journal Articles

Abstract 3909: THY1 regulates therapy resistance in glioblastoma recurrence

Sunita Shankar, Visweswaran Ravikumar, Hanxiao Wang, Sunjong Ji, Zainab Hasan, Ziad Fehmi, Yacoub Haydin, Daniel R. Wahl, Arvind Rao, Alnawaz Rehemtulla, Wajd Al-Holou

Cancer Res (2023) 83 (7_Supplement): 3909.

https://doi.org/10.1158/1538-7445.AM2023-3909

Published: 04 April 2023

View articletitled, Abstract 3909: THY1 regulates therapy resistance in glioblastoma recurrence

Journal Articles

Abstract 1093: Measuring and inhibiting purine metabolism in patients with glioblastoma

Cancer Res (2023) 83 (7_Supplement): 1093.

https://doi.org/10.1158/1538-7445.AM2023-1093

Published: 04 April 2023

View articletitled, Abstract 1093: Measuring and inhibiting purine metabolism in patients with glioblastoma

Journal Articles

Abstract 3677: DNA damage signaling activates de novo GTP synthesis to promote chemoradiation resistance in glioblastoma

Cancer Res (2023) 83 (7_Supplement): 3677.

https://doi.org/10.1158/1538-7445.AM2023-3677

Published: 04 April 2023

View articletitled, Abstract 3677: DNA damage signaling activates de novo GTP synthesis to promote chemoradiation resistance in glioblastoma

Journal Articles

Abstract 2820: Defining the role of purine metabolism in radiation resistance in H3K27M–mutant diffuse midline glioma

Erik R. Peterson, Peter Sajjakulnukit, Andrew Scott, Caleb Heaslip, Costas Lyssiotis, Maria G. Castro, Daniel R. Wahl

Cancer Res (2023) 83 (7_Supplement): 2820.

https://doi.org/10.1158/1538-7445.AM2023-2820

Published: 04 April 2023

View articletitled, Abstract 2820: Defining the role of purine metabolism in radiation resistance in H3K27M–mutant diffuse midline glioma

Journal Articles

Abstract 3498: GTP-dependent signaling links metabolism, non-homologous end joining and treatment responses in cancer and normal tissues

Cancer Res (2023) 83 (7_Supplement): 3498.

https://doi.org/10.1158/1538-7445.AM2023-3498

Published: 04 April 2023

View articletitled, Abstract 3498: GTP-dependent signaling links metabolism, non-homologous end joining and treatment responses in cancer and normal tissues

Journal Articles

Abstract 331: Mitochondrial transfer from astrocytes drives glioblastoma tumorigenicity

Dionysios C. Watson, Defne Bayik, Simon Storevik, Shannon S. Moreino, Samuel S. Sprowls, Gauravi Deshpande, Palavalasa Sravya, Costas A. Lyssiotis, Daniel R. Wahl, Hrvoje Miletic, Justin D. Lathia

Cancer Res (2023) 83 (7_Supplement): 331.

https://doi.org/10.1158/1538-7445.AM2023-331

Published: 04 April 2023

View articletitled, Abstract 331: Mitochondrial transfer from astrocytes drives glioblastoma tumorigenicity

Journal Articles

Abstract 1095: Exploiting altered methionine metabolism to overcome treatment resistance in glioblastoma

Navyateja Korimerla, Kari-Wilder Romans, Peter Kalev, Ayesha Kothari, Nathan Qi, Charles Evans, Maureen Kachman, Marc L Hyer, Katya Marjon, Taryn Sleger, Daniel R Wahl

Cancer Res (2023) 83 (7_Supplement): 1095.

https://doi.org/10.1158/1538-7445.AM2023-1095

Published: 04 April 2023

View articletitled, Abstract 1095: Exploiting altered methionine metabolism to overcome treatment resistance in glioblastoma

Journal Articles

A Complementary Strategy to Mitigate Radiation-Induced Cognitive Decline

Navyateja Korimerla, Daniel R. Wahl

Cancer Res (2021) 81 (7): 1635–1636.

https://doi.org/10.1158/0008-5472.CAN-20-4277

Published: 01 April 2021

View articletitled, A Complementary Strategy to Mitigate Radiation-Induced Cognitive Decline

Journal Articles

Abstract 6267: Repurposing antiandrogens to overcome therapy resistance in androgen receptor-positive glioblastoma

Cancer Res (2020) 80 (16_Supplement): 6267.

https://doi.org/10.1158/1538-7445.AM2020-6267

Published: 15 August 2020

View articletitled, Abstract 6267: Repurposing antiandrogens to overcome therapy resistance in androgen receptor-positive glioblastoma

Journal Articles

Abstract 6271: Hormone receptor inhibition as a strategy for radiosensitization of breast cancer

Anna R. Michmerhuizen, Amanda Zhang, Rachel Schwartz, Andrea M. Pesch, Benjamin C. Chandler, Cassandra L. Ritter, Meilan Liu, Kari Wilder-Romans, Daniel E. Spratt, Daniel R. Wahl, Shyam Nyati, Lori J. Pierce, Corey Speers

Cancer Res (2020) 80 (16_Supplement): 6271.

https://doi.org/10.1158/1538-7445.AM2020-6271

Published: 15 August 2020

View articletitled, Abstract 6271: Hormone receptor inhibition as a strategy for radiosensitization of breast cancer

Journal Articles

Inhibition of ATM Increases Interferon Signaling and Sensitizes Pancreatic Cancer to Immune Checkpoint Blockade Therapy

Qiang Zhang, Michael D. Green, Xueting Lang, Jenny Lazarus, Joshua D. Parsels, Shuang Wei, Leslie A. Parsels, Jiaqi Shi, Nithya Ramnath, Daniel R. Wahl, Marina Pasca di Magliano, Timothy L. Frankel, Ilona Kryczek, Yu L. Lei, Theodore S. Lawrence, Weiping Zou, Meredith A. Morgan

Cancer Res (2019) 79 (15): 3940–3951.

https://doi.org/10.1158/0008-5472.CAN-19-0761

Published: 01 August 2019

View articletitled, Inhibition of ATM Increases Interferon Signaling and Sensitizes Pancreatic Cancer to Immune Checkpoint Blockade Therapy

Includes: Supplementary data

Journal Articles

Glioblastoma Therapy Can Be Augmented by Targeting IDH1-Mediated NADPH Biosynthesis

Daniel R. Wahl, Joseph Dresser, Kari Wilder-Romans, Joshua D. Parsels, Shuang G. Zhao, Mary Davis, Lili Zhao, Maureen Kachman, Stefanie Wernisch, Charles F. Burant, Meredith A. Morgan, Felix Y. Feng, Corey Speers, Costas A. Lyssiotis, Theodore S. Lawrence

Cancer Res (2017) 77 (4): 960–970.

https://doi.org/10.1158/0008-5472.CAN-16-2008

Published: 14 February 2017

View articletitled, Glioblastoma Therapy Can Be Augmented by Targeting IDH1-Mediated NADPH Biosynthesis

Includes: Supplementary data

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Abstract 1140: Digital twins for in vivo metabolic flux estimations in brain cancer patients

Abstract 1789: Machine learning-based method to analyze metabolic fluxes of patient tumors

Abstract 1801: Rewiring of cortical glucose metabolism fuels human brain cancer growth

Abstract A004: GTP signaling links metabolism, DNA repair, and responses to genotoxic stress

Abstract B045: Adaptive purine metabolism drives radiation therapy resistance in H3K27M-diffuse midline glioma

Abstract B051: DNA damage signaling activates GTP synthesis to promote glioblastoma treatment resistance

Abstract 3909: THY1 regulates therapy resistance in glioblastoma recurrence

Abstract 1093: Measuring and inhibiting purine metabolism in patients with glioblastoma

Abstract 3677: DNA damage signaling activates de novo GTP synthesis to promote chemoradiation resistance in glioblastoma

Abstract 2820: Defining the role of purine metabolism in radiation resistance in H3K27M–mutant diffuse midline glioma

Abstract 3498: GTP-dependent signaling links metabolism, non-homologous end joining and treatment responses in cancer and normal tissues

Abstract 331: Mitochondrial transfer from astrocytes drives glioblastoma tumorigenicity

Abstract 1095: Exploiting altered methionine metabolism to overcome treatment resistance in glioblastoma

A Complementary Strategy to Mitigate Radiation-Induced Cognitive Decline

Abstract 6267: Repurposing antiandrogens to overcome therapy resistance in androgen receptor-positive glioblastoma

Abstract 6271: Hormone receptor inhibition as a strategy for radiosensitization of breast cancer

Inhibition of ATM Increases Interferon Signaling and Sensitizes Pancreatic Cancer to Immune Checkpoint Blockade Therapy

Glioblastoma Therapy Can Be Augmented by Targeting IDH1-Mediated NADPH Biosynthesis

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