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Dan Theodorescu
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Journal Articles

Development of Novel Aptamer-Based Targeted Chemotherapy for Bladder Cancer

Yao Wang, Yang Zhang, Peng-Chao Li, Jiajie Guo, Fan Huo, Jintao Yang, Ru Jia, Juan Wang, Qiju Huang, Dan Theodorescu, Hanyang Yu, Chao Yan
Journal: Cancer Research
Cancer Res (2022) 82 (6): 1128–1139.
https://doi.org/10.1158/0008-5472.CAN-21-2691
Published: 15 March 2022
View article titled, Development of Novel Aptamer-Based Targeted Chemotherapy for Bladder Cancer
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Includes: Supplementary data
Journal Articles

Abstract 614: Transcriptomic analysis of BCG-treated T1HG bladder cancer patients identifies an EMT-basal subgroup with immune suppressive characteristics at high risk of BCG-failure

Florus C. De Jong, Teemu D. Laajala, Robert F. Hoedemaeker, Sébastien Rinaldetti, Jolien T. Mensink, Angelique C. Van der Made, Deric K. Van der Schoot, Egbert R. Boevé, Ellen C. Zwarthoff, Joost L. Boormans, Dan Theodorescu, James C. Costello, Tahlita C. Zuiverloon
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 614.
https://doi.org/10.1158/1538-7445.AM2021-614
Published: 01 July 2021
View article titled, Abstract 614: Transcriptomic analysis of BCG-treated T1HG bladder cancer patients identifies an EMT-basal subgroup with immune suppressive characteristics at high risk of BCG-failure
Journal Articles

Abstract 615: Differential pathway analyses of BCG-treated T1HG bladder cancer using Philips OncoSignal: A pilot study

Florus C. De Jong, Teemu D. Laajala, Robert F. Hoedemaeker, Sébastien Rinaldetti, Jolien T. Mensink, Angelique C. Van Der Made, Deric K. Van der Schoot, Egbert R. Boevé, Ellen C. Zwarthoff, Joost L. Boormans, Dan Theodorescu, James C. Costello, Tahlita C. Zuiverloon
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 615.
https://doi.org/10.1158/1538-7445.AM2021-615
Published: 01 July 2021
View article titled, Abstract 615: Differential pathway analyses of BCG-treated T1HG bladder cancer using Philips OncoSignal: A pilot study
Journal Articles

Androgen Receptor Regulates CD44 Expression in Bladder Cancer

Joseph L. Sottnik, Lauren Vanderlinden, Molishree Joshi, Ana Chauca-Diaz, Charles Owens, Donna E. Hansel, Colin Sempeck, Debashis Ghosh, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2021) 81 (11): 2833–2846.
https://doi.org/10.1158/0008-5472.CAN-20-3095
Published: 01 June 2021
View article titled, Androgen Receptor Regulates CD44 Expression in Bladder Cancer
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Includes: Supplementary data
Journal Articles

Abstract 4091: Functional genomic screening in gemcitabine and cisplatin resistant bladder cancer cell lines identifies DNA repair pathways as mediators of chemosensitivity

Robert T. Jones, Tahlita C. Zuiverloon, Hedvig Vekony, Andrew Goodspeed, Teemu D. Laajala, Molishree Joshi, Colin Sempeck, Annie Jean, Megan Tu, Julia D. Wulfkuhle, Emanuel F. Petricoin, James C. Costello, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4091.
https://doi.org/10.1158/1538-7445.AM2020-4091
Published: 15 August 2020
View article titled, Abstract 4091: Functional genomic screening in gemcitabine and cisplatin resistant bladder cancer cell lines identifies DNA repair pathways as mediators of chemosensitivity
Journal Articles

Abstract 4085: DDR2 inhibition enhances response to anti-PD-1 immunotherapy

Megan M. Tu, Francis Y. Lee, Robert T. Jones, Abigail K. Kimball, Elizabeth Saravia, Robert F. Graziano, Brianne Coleman, Krista Menard, Jun Yan, Erin Michaud, Han Chang, Hany A. Abdel-Hafiz, Andrii I. Rozhok, Jason E. Duex, Neeraj Agarwal, Ana Chauca-Diaz, Linda K. Johnson, Terry L. Ng, John C. Cambier, Eric T. Clambey, James C. Costello, Alan J. Korman, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4085.
https://doi.org/10.1158/1538-7445.AM2019-4085
Published: 01 July 2019
View article titled, Abstract 4085: DDR2 inhibition enhances response to anti-PD-1 immunotherapy
Journal Articles

Abstract 2107: Integrative molecular and functional genomic analysis of chemotherapy resistant bladder cancer cell lines identifies novel mediators of therapeutic response

Robert T. Jones, Tahlita C. Zuiverloon, Hedvig Vekony, Andrew Goodspeed, Teemu D. Laajala, Molishree Joshi, Colin Sempeck, Megan Tu, James C. Costello, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2107.
https://doi.org/10.1158/1538-7445.AM2019-2107
Published: 01 July 2019
View article titled, Abstract 2107: Integrative molecular and functional genomic analysis of chemotherapy resistant bladder cancer cell lines identifies novel mediators of therapeutic response
Journal Articles

Nuclear CD24 Drives Tumor Growth and Is Predictive of Poor Patient Prognosis

Jason E. Duex, Charles Owens, Ana Chauca-Diaz, Garrett M. Dancik, Lauren A. Vanderlinden, Debashis Ghosh, Mariah Z. Leivo, Donna E. Hansel, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2017) 77 (18): 4858–4867.
https://doi.org/10.1158/0008-5472.CAN-17-0367
Published: 14 September 2017
View article titled, Nuclear CD24 Drives Tumor Growth and Is Predictive of Poor Patient Prognosis
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Includes: Supplementary data
Journal Articles

Abstract 3352: Genome-wide enhancer identify signature predictive of metastatic phenotypes in bladder cancers

Sohyoung Kim, Lyuba Varticovski, Qizong Lao, Songjoon Baek, Michael L. Nickerson, Myong-Hee Sung, Lars Grontved, Thompson Bethtrice, Dan Theodorescu, Piyush K. Agarwal, Michael Dean, Gordon Hager
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3352.
https://doi.org/10.1158/1538-7445.AM2017-3352
Published: 01 July 2017
View article titled, Abstract 3352: Genome-wide enhancer identify signature predictive of metastatic phenotypes in bladder cancers
Journal Articles

Abstract SY36-01: Optimizing neoadjuvant therapy prior to surgery: Biomarker and target discovery

Dan Theodorescu
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): SY36-01.
https://doi.org/10.1158/1538-7445.AM2017-SY36-01
Published: 01 July 2017
View article titled, Abstract SY36-01: Optimizing neoadjuvant therapy prior to surgery: Biomarker and target discovery
Journal Articles

GON4L Drives Cancer Growth through a YY1–Androgen Receptor–CD24 Axis

Neeraj Agarwal, Garrett M. Dancik, Andrew Goodspeed, James C. Costello, Charles Owens, Jason E. Duex, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2016) 76 (17): 5175–5185.
https://doi.org/10.1158/0008-5472.CAN-16-1099
Published: 31 August 2016
View article titled, GON4L Drives Cancer Growth through a YY1–Androgen Receptor–CD24 Axis
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Includes: Supplementary data
Journal Articles

Abstract 1140: CD24 exists in the nucleus and drives cancer growth

Jason Duex, Changho Lee, Charles Owens, Ana Chauca-Diaz, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1140.
https://doi.org/10.1158/1538-7445.AM2016-1140
Published: 15 July 2016
View article titled, Abstract 1140: CD24 exists in the nucleus and drives cancer growth
Journal Articles

Abstract A52: Gene alterations associated with clinical characteristics of bladder cancer

Mike Nickerson, Kate M. Im, Guangwu Guo, Yaoting Gui, Sevilay Turan, James C. Costello, Quan Zhou, Zhiming Cai, Song Wu, M. Scott Lucia, Lee E. Moore, Michael Dean, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2016) 76 (2_Supplement): A52.
https://doi.org/10.1158/1538-7445.CHROMEPI15-A52
Published: 14 January 2016
View article titled, Abstract A52: Gene alterations associated with clinical characteristics of bladder cancer
Journal Articles

Abstract A1-01: Translational genomics of urologic cancer genes

Michael L. Nickerson, Kate M. Im, Sevilay Turan, Guangwu Guo, Lee E. Moore, Dan Theodorescu, Michael Dean
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_1): A1-01.
https://doi.org/10.1158/1538-7445.TRANSCAGEN-A1-01
Published: 15 November 2015
View article titled, Abstract A1-01: Translational genomics of urologic cancer genes
Journal Articles

Abstract 1105: Clinical associations between altered bladder cancer genes

Michael L. Nickerson, Kate M. Im, Sevilay Turan, Lee E. Moore, Michael Dean, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1105.
https://doi.org/10.1158/1538-7445.AM2015-1105
Published: 01 August 2015
View article titled, Abstract 1105: Clinical associations between altered bladder cancer genes
Journal Articles

Abstract 4949: HAS2 is a critical effector for AGL mediated regulation of tumor growth

Sunny Guin, Yuanbin Ru, Carolyn R. Lew, Neeraj Agarwal, Charles Owens, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4949.
https://doi.org/10.1158/1538-7445.AM2015-4949
Published: 01 August 2015
View article titled, Abstract 4949: HAS2 is a critical effector for AGL mediated regulation of tumor growth
Journal Articles

Abstract 4783: Novel molecular markers of bladder cancer progression identified by global chromatin profiling

Lyuba Varticovski, Sohyoung Kim, Michael L. Nickerson, Bethtrice Thompson, Qizong Lao, Lars Grøntved, Songjoon Baek, Myong-Hee Sung, Dan Theodorescu, Michael Dean, Gordon L. Hager
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4783.
https://doi.org/10.1158/1538-7445.AM2015-4783
Published: 01 August 2015
View article titled, Abstract 4783: Novel molecular markers of bladder cancer progression identified by global chromatin profiling
Journal Articles

Abstract 4782: Genome-wide chromatin profiling in bladder and prostate cancers

Sohyoung Kim, Lyuba Varticovski, Qizong Lao, Songjoon Baek, Myong-Hee Sung, Lars Grøntved, Michael L. Nickerson, Bethtrice Thompson, Dan Theodorescu, Michael Dean, Gordon H. Hager
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4782.
https://doi.org/10.1158/1538-7445.AM2015-4782
Published: 01 August 2015
View article titled, Abstract 4782: Genome-wide chromatin profiling in bladder and prostate cancers
Journal Articles

Cellular Disposal of miR23b by RAB27-Dependent Exosome Release Is Linked to Acquisition of Metastatic Properties

Marie Stampe Ostenfeld, Dennis K. Jeppesen, Jens R. Laurberg, Anders T. Boysen, Jesper B. Bramsen, Bjarke Primdal-Bengtson, An Hendrix, Philippe Lamy, Frederik Dagnaes-Hansen, Mads H. Rasmussen, Khan H. Bui, Niels Fristrup, Erik I. Christensen, Iver Nordentoft, Jens P. Morth, Jørgen B. Jensen, Jakob S. Pedersen, Martin Beck, Dan Theodorescu, Michael Borre, Kenneth A. Howard, Lars Dyrskjøt, Torben Falck Ørntoft
Journal: Cancer Research
Cancer Res (2014) 74 (20): 5758–5771.
https://doi.org/10.1158/0008-5472.CAN-13-3512
Published: 14 October 2014
View article titled, Cellular Disposal of miR23b by RAB27-Dependent Exosome Release Is Linked to Acquisition of Metastatic Properties
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Includes: Supplementary data
Journal Articles

Abstract 2379: The importance of cell cycle biomarkers in prognostic signatures in tobacco-related cancers.

Garrett Dancik, Dan Theodorescu
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2379.
https://doi.org/10.1158/1538-7445.AM2013-2379
Published: 15 April 2013
View article titled, Abstract 2379: The importance of cell cycle biomarkers in prognostic signatures in tobacco-related cancers.