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Dale L. Ludwig
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Journal Articles

Abstract 1518: Dose optimization and radiation dosimetry of CD45-targeting 225Actinium-armed antibody as a conditioning agent for adoptive cell therapy

Ravendra Garg, Qing Liang, Eileen M. Geoghegan, Kevin J. Allen, Wojciech Dawicki, Dale L. Ludwig, Ekaterina Dadachova
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1518.
https://doi.org/10.1158/1538-7445.AM2021-1518
Published: 01 July 2021
View article titled, Abstract 1518: Dose optimization and radiation dosimetry of CD45-targeting 225Actinium-armed antibody as a conditioning agent for adoptive cell therapy
Journal Articles

Abstract 3808: 225Ac-CD33 Radioimmunotherapy potently increases the sensitivity of resistant acute myeloid leukemia lines to the Bcl-2 inhibitor venetoclax by mediating a reduction in cellular Mcl-1 levels

Ravendra Garg, Eileen Geoghegan, Kevin J. Allen, Wojciech Dawicki, Ekaterina Dadachova, Dale L. Ludwig
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3808.
https://doi.org/10.1158/1538-7445.AM2019-3808
Published: 01 July 2019
View article titled, Abstract 3808: <sup>225</sup>Ac-CD33 Radioimmunotherapy potently increases the sensitivity of resistant acute myeloid leukemia lines to the Bcl-2 inhibitor venetoclax by mediating a reduction in cellular Mcl-1 levels
Journal Articles

Abstract 2730: Preclinical characterization of the anti-PD-L1 monoclonal antibody LY3300054

Carmine Carpenito, Yiwen Li, George X. Wang, Maria S. Malabunga, Jaafar N. Haidar, Amelie Forest, Mary Y. Murphy, Gerald E. Hall, Cindy Wang, Leyi Shen, Andreas Sonyi, Darin Chin, Anthony L. Pennello, Ivan V. Inigo, David Surguladze, Yung-mae Yao, Douglas Burtrum, Ruslan D. Novosiadly, Kris Persaud, Dale L. Ludwig, Michael D. Kalos
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2730.
https://doi.org/10.1158/1538-7445.AM2018-2730
Published: 01 July 2018
View article titled, Abstract 2730: Preclinical characterization of the anti-PD-L1 monoclonal antibody LY3300054
Journal Articles

Insulin-like Growth Factor-I Receptor Signaling Blockade Combined with Radiation

Gregory W. Allen, Corey Saba, Eric A. Armstrong, Shyh-Min Huang, Sergio Benavente, Dale L. Ludwig, Daniel J. Hicklin, Paul M. Harari
Journal: Cancer Research
Cancer Res (2007) 67 (3): 1155–1162.
https://doi.org/10.1158/0008-5472.CAN-06-2000
Published: 05 February 2007
View article titled, Insulin-like Growth Factor-I Receptor Signaling Blockade Combined with Radiation
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Journal Articles

Therapeutic Implications of a Human Neutralizing Antibody to the Macrophage-Stimulating Protein Receptor Tyrosine Kinase (RON), a c-MET Family Member

Jennifer M. O'Toole, Karen E. Rabenau, Kerri Burns, Dan Lu, Venkat Mangalampalli, Paul Balderes, Nicole Covino, Rajiv Bassi, Marie Prewett, Kimberly J. Gottfredsen, Megan N. Thobe, Yuan Cheng, Yiwen Li, Daniel J. Hicklin, Zhenping Zhu, Susan E. Waltz, Michael J. Hayman, Dale L. Ludwig, Daniel S. Pereira
Journal: Cancer Research
Cancer Res (2006) 66 (18): 9162–9170.
https://doi.org/10.1158/0008-5472.CAN-06-0283
Published: 18 September 2006
View article titled, Therapeutic Implications of a Human Neutralizing Antibody to the Macrophage-Stimulating Protein Receptor Tyrosine Kinase (RON), a c-MET Family Member
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Includes: Supplementary data
Journal Articles

Breast cancer cell lines resistant to either tamoxifen or Herceptin exhibit sensitivity to the anti-IGF receptor antibody A12 in vitro

Carolyn J M Best, Dale L. Ludwig, Patricia S. Steeg
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 290.
Published: 15 April 2006
View article titled, Breast cancer cell lines resistant to either tamoxifen or Herceptin exhibit sensitivity to the anti-IGF receptor antibody A12 in vitro
Journal Articles

Therapeutic implications of a human neutralizing antibody to the Macrophage-Stimulating Protein receptor tyrosine kinase (RON) that inhibits cancer cell signaling, migration and tumorigenesis

Jennifer M. O’Toole, Karen E. Rabenau, Kerri Burns, Yuan Cheng, Dan Lu, Venkat R. M. Mangalampalli, Paul Balderes, Marie C. Prewett, Zhenping Zhu, Dale L. Ludwig, Larry Witte, Daniel S. Pereira
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 876.
Published: 15 April 2006
View article titled, Therapeutic implications of a human neutralizing antibody to the Macrophage-Stimulating Protein receptor tyrosine kinase (RON) that inhibits cancer cell signaling, migration and tumorigenesis
Journal Articles

mTOR Inhibition Induces Upstream Receptor Tyrosine Kinase Signaling and Activates Akt

Kathryn E. O'Reilly, Fredi Rojo, Qing-Bai She, David Solit, Gordon B. Mills, Debra Smith, Heidi Lane, Francesco Hofmann, Daniel J. Hicklin, Dale L. Ludwig, Jose Baselga, Neal Rosen
Journal: Cancer Research
Cancer Res (2006) 66 (3): 1500–1508.
https://doi.org/10.1158/0008-5472.CAN-05-2925
Published: 01 February 2006
View article titled, mTOR Inhibition Induces Upstream Receptor Tyrosine Kinase Signaling and Activates Akt
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Journal Articles

Suppression of leukemia growth in vivo by a novel anti-FLT3 antibody-auristatin conjugate

Yiwen Li, Hongli Li, Mei-Nai Wang, Rajiv Bassi, Venkat Mangalampalli, Dale L. Ludwig, Paul Balderes, Larry Witte, Zhenping Zhu, Damon Meyer, Angelyn Larkin, Peter Senter, Peter Bohlen, Daniel J. Hicklin
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1455.
Published: 01 May 2005
View article titled, Suppression of leukemia growth in vivo by a novel anti-FLT3 antibody-auristatin conjugate
Journal Articles

A humanized insulin-like growth factor I receptor antibody inhibits multiple myeloma cell growth in vivo through anti-angiogenesis

Kaida Wu, Li Zhou, Kang Zhang, Douglas Burtrum, Dale L. Ludwig, Malcolm A. S. Moore
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1189.
Published: 01 May 2005
View article titled, A humanized insulin-like growth factor I receptor antibody inhibits multiple myeloma cell growth in vivo through anti-angiogenesis
Journal Articles

Synergistic anti-tumor effects of anti-EGFR monoclonal antibody Erbitux® combined with antibodies targeting IGF1R or VEGFR-2

James R. Tonra, Erik Corcoran, Genevieve Makhoul, Douglas Burtrum, Bridget Finnerty, James Huber, Francine E. Carrick, Dale L. Ludwig, Daniel J. Hicklin
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1193.
Published: 01 May 2005
View article titled, Synergistic anti-tumor effects of anti-EGFR monoclonal antibody Erbitux® combined with antibodies targeting IGF1R or VEGFR-2
Journal Articles

Therapeutic implications of an antibody to the human macrophage-stimulating protein receptor tyrosine kinase (RON)

Daniel S. Pereira, Jennifer M. O’Toole, Karen E. Rabenau, Dan Lu, Venkat Mangalampalli, Henry Koo, Anthony Kayas, Julie P. Yuen, Paul Balderes, Nicole Covino, Rajiv Bassi, Andrea Hooper, Philipp Steiner, Xenia Jimenez, Zhenping Zhu, Dale L. Ludwig, Daniel J. Hicklin, Larry Witte
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 130–131.
Published: 01 May 2005
View article titled, Therapeutic implications of an antibody to the human macrophage-stimulating protein receptor tyrosine kinase (RON)
Journal Articles

Inhibitory Anti-FLT3 Antibodies Are Capable of Mediating Antibody-Dependent Cell-Mediated Cytotoxicity and Reducing Engraftment of Acute Myelogenous Leukemia Blasts in Nonobese Diabetic/Severe Combined Immunodeficient Mice

Obdulio Piloto, Mark Levis, David Huso, Yiwen Li, Hongli Li, Mei-Nai Wang, Rajiv Bassi, Paul Balderes, Dale L. Ludwig, Larry Witte, Zhenping Zhu, Daniel J. Hicklin, Donald Small
Journal: Cancer Research
Cancer Res (2005) 65 (4): 1514–1522.
https://doi.org/10.1158/0008-5472.CAN-04-3081
Published: 25 February 2005
View article titled, Inhibitory Anti-FLT3 Antibodies Are Capable of Mediating Antibody-Dependent Cell-Mediated Cytotoxicity and Reducing Engraftment of Acute Myelogenous Leukemia Blasts in Nonobese Diabetic/Severe Combined Immunodeficient Mice
Open the PDF for Inhibitory Anti-FLT3 Antibodies Are Capable of Mediating Antibody-Dependent Cell-Mediated Cytotoxicity and Reducing Engraftment of Acute Myelogenous Leukemia Blasts in Nonobese Diabetic/Severe Combined Immunodeficient Mice in another window
Journal Articles

DEGA/AMIGO-2, a leucine-rich repeat family member differentially expressed in human gastric adenocarcinoma: Effects on ploidy, chromosomal stability and tumorigenicity

Daniel S. Pereira, Karen E. Rabenau, Jennifer M. O’Toole, Rajiv Bassi, Helen Kotanides, Dale L. Ludwig, Larry Witte
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1168.
Published: 01 April 2004
View article titled, DEGA/AMIGO-2, a leucine-rich repeat family member differentially expressed in human gastric adenocarcinoma: Effects on ploidy, chromosomal stability and tumorigenicity
Journal Articles

Potent anti-tumor activity of IGF-I receptor antagonist antibody IMC-A12 alone and in combination with CPT-11.

Dale L. Ludwig, James R. Tonra, Douglas Burtrum, Marie Prewett, Rajiv Bassi, Andrea Hooper, Daniel S. Pereira, Bridget Finnerty, Eric Corcoran, Larry Witte, Daniel J. Hicklin
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 509.
Published: 01 April 2004
View article titled, Potent anti-tumor activity of IGF-I receptor antagonist antibody IMC-A12 alone and in combination with CPT-11.
Journal Articles

A Fully Human Monoclonal Antibody to the Insulin-Like Growth Factor I Receptor Blocks Ligand-Dependent Signaling and Inhibits Human Tumor Growth in Vivo

Douglas Burtrum, Zhenping Zhu, Dan Lu, Donna Marie Anderson, Marie Prewett, Daniel S. Pereira, Rajiv Bassi, Rashed Abdullah, Andrea T. Hooper, Henry Koo, Xenia Jimenez, Danielle Johnson, Robin Apblett, Paul Kussie, Peter Bohlen, Larry Witte, Daniel J. Hicklin, Dale L. Ludwig
Journal: Cancer Research
Cancer Res (2003) 63 (24): 8912–8921.
Published: 24 December 2003
View article titled, A Fully Human Monoclonal Antibody to the Insulin-Like Growth Factor I Receptor Blocks Ligand-Dependent Signaling and Inhibits Human Tumor Growth <em>in Vivo</em>
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