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Journal Articles

Abstract A040: Multiplex fluorescent immunohistochemistry reveals immunosuppressive tumor microenvironment in COMPASS-like complex gene mutated pancreatic cancer

Shungang Zhang, Elaina Daniels, Jake McGue, Hong Sun Kim, Dafydd Thomas, Timothy Frankel, Jiaqi Shi
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): A040.
https://doi.org/10.1158/1538-7445.PANCREATIC24-A040
Published: 15 September 2024
View article titled, Abstract A040: Multiplex fluorescent immunohistochemistry reveals immunosuppressive tumor microenvironment in COMPASS-like complex gene mutated pancreatic cancer
Journal Articles

Abstract A045: Disrupting local immunosuppression through combination myCAF/myeloid targeting in pancreatic cancer

Marie C Hasselluhn, Lukas Vlahos, Dafydd Thomas, Quin T Waterbury, Alvaro Curiel Garcia, Amanda R Decker-Farrell, Tanner C Dalton, Stephen A Sastra, Carmine F Palermo, Timothy C Wang, Andrea Califano, Kenneth P Olive
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): A045.
https://doi.org/10.1158/1538-7445.PANCREATIC24-A045
Published: 15 September 2024
View article titled, Abstract A045: Disrupting local immunosuppression through combination myCAF/myeloid targeting in pancreatic cancer
Journal Articles

Abstract 1596: Disrupting local immunosuppression by combined myCAF/myeloid targeting in pancreatic cancer

Marie C. Hasselluhn, Dafydd Thomas, Lukas Vlahos, Alvaro Curiel-Garcia, Amanda R. Decker-Farrell, Tanner C. Dalton, Stephen A. Sastra, Carmine F. Palermo, Andrea Califano, Kenneth P. Olive
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1596.
https://doi.org/10.1158/1538-7445.AM2024-1596
Published: 22 March 2024
View article titled, Abstract 1596: Disrupting local immunosuppression by combined myCAF/myeloid targeting in pancreatic cancer
Journal Articles

Abstract C045: Multiplex fluorescent immunohistochemistry reveals immune microenvironment alterations in COMPASS-like complex gene mutated pancreatic cancer

Shungang Zhang, Jake McGue, Elaina Daniels, Hong Sun Kim, Dafydd Thomas, Jiaqi Shi
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): C045.
https://doi.org/10.1158/1538-7445.PANCA2023-C045
Published: 16 January 2024
View article titled, Abstract C045: Multiplex fluorescent immunohistochemistry reveals immune microenvironment alterations in COMPASS-like complex gene mutated pancreatic cancer
Journal Articles

Abstract C032: Combination CAF/myeloid targeting in PDAC

Marie C. Hasselluhn, Lukas J. Vlahos, Dafydd Thomas, Alvaro Curiel Garcia, Amanda R. Decker, Tanner C. Dalton, Stephen A. Sastra, Carmine F. Palermo, Andrea Califano, Kenneth P. Olive
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): C032.
https://doi.org/10.1158/1538-7445.PANCA22-C032
Published: 15 November 2022
View article titled, Abstract C032: Combination CAF/myeloid targeting in PDAC
Journal Articles

Abstract PR-014: Hedgehog represses angiogenesis in PDAC through a paracrine cascade mediated by Wif1

Marie C. Hasselluhn, Amanda R. Decker, Alvaro Curiel Garcia, Carlo Maurer, Dafydd Thomas, Kenneth P. Olive
Journal: Cancer Research
Cancer Res (2021) 81 (22_Supplement): PR-014.
https://doi.org/10.1158/1538-7445.PANCA21-PR-014
Published: 15 November 2021
View article titled, Abstract PR-014: Hedgehog represses angiogenesis in PDAC through a paracrine cascade mediated by Wif1
Journal Articles

Abstract LB006: PC14586: The first orally bioavailable small molecule reactivator of Y220C mutant p53 in clinical development

Melissa Dumble, Lizhong Xu, Romyr Dominique, Binbin Liu, Hong Yang, Mary-Kate McBrayer, Dafydd Thomas, Bruce Fahr, Hongju Li, Kuo-Sen Huang, Kimberly Robell, Chris Mulligan, Brandon Russo, Anna Puzio-Kuter, Thomas Davis, Binh Vu
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB006.
https://doi.org/10.1158/1538-7445.AM2021-LB006
Published: 01 July 2021
View article titled, Abstract LB006: PC14586: The first orally bioavailable small molecule reactivator of Y220C mutant p53 in clinical development
Journal Articles

Abstract 6273: TTK inhibition radiosensitizes basal-like breast cancer through impaired homologous recombination

Benjamin Chandler, Leah Moubadder, Cassandra Ritter, Meilan Liu, Meleah Cameron, Kari Wilder-Romans, Amanda Zhang, Andrea Pesch, Anna Michmerhuizen, Nicole Hirsh, Marlie Androsiglio, Tanner Ward, Eric Olsen, Yashar Niknafs, Sofia Merajver, Dafydd Thomas, Powel Brown, Theodore Lawrence, Shyam Nyati, Lori Pierce, Arul Chinnaiyan, Corey Speers
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6273.
https://doi.org/10.1158/1538-7445.AM2020-6273
Published: 15 August 2020
View article titled, Abstract 6273: TTK inhibition radiosensitizes basal-like breast cancer through impaired homologous recombination
Journal Articles

Abstract 3645: Cooperation between canonical Wnt and TGF-beta pathways promotes sarcoma angiogenesis

Allegra G. Hawkins, Elisabeth A. Pedersen, Wei Jiang, Sydney Treichel, Colin Sperring, Jay Read, Brian Magnuson, Rajiv M. Patel, Dafydd Thomas, Rashmi Chugh, Elizabeth R. Lawlor
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3645.
https://doi.org/10.1158/1538-7445.AM2019-3645
Published: 01 July 2019
View article titled, Abstract 3645: Cooperation between canonical Wnt and TGF-beta pathways promotes sarcoma angiogenesis
Journal Articles

HER2 and EGFR Overexpression Support Metastatic Progression of Prostate Cancer to Bone

Kathleen C. Day, Guadalupe Lorenzatti Hiles, Molly Kozminsky, Scott J. Dawsey, Alyssa Paul, Luke J. Broses, Rajal Shah, Lakshmi P. Kunja, Christopher Hall, Nallasivam Palanisamy, Stephanie Daignault-Newton, Layla El-Sawy, Steven James Wilson, Andrew Chou, Kathleen Woods Ignatoski, Evan Keller, Dafydd Thomas, Sunitha Nagrath, Todd Morgan, Mark L. Day
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (1): 74–85.
https://doi.org/10.1158/0008-5472.CAN-16-1656
Published: 02 January 2017
View article titled, HER2 and EGFR Overexpression Support Metastatic Progression of Prostate Cancer to Bone
Open the PDF for HER2 and EGFR Overexpression Support Metastatic Progression of Prostate Cancer to Bone in another window
Includes: Supplementary data
Journal Articles

Abstract 3568: CYP3A4 epoxygenase activity mediates ER+ mammary tumor growth and angiogenesis, in part, through EET biosynthesis and is inhibited by biguanides

Zhijun Guo, Irina F. Sevrioukova, Eric Hanse, Ilia Denisov, Xia Zhang, Ting-Lan Chiu, Daniel Swedien, Justin Stamschror, Juan Alvarez, William Marerro Ortiz, Monique Morgan, Michael Maher, Kathryn J. Chavez, Dafydd Thomas, Young Kyung Bae, Jonathan Henriksen, Beverly Norris, Robert J. Schumacher, Henry Wang, Robin Bliss, Haitao Chu, Rebecca Cuellar, Thomas L. Poulos, Stephen G. Sligar, William Atkins, Stephen Schmechel, Jorge Capdevila, John Falck, Ian Blair, Jeffrey P. Jones, Gunda Georg, Kalpna Gupta, Ameeta Kelekar, Elizabeth Amin, David A. Potter
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3568.
https://doi.org/10.1158/1538-7445.AM2015-3568
Published: 01 August 2015
View article titled, Abstract 3568: CYP3A4 epoxygenase activity mediates ER+ mammary tumor growth and angiogenesis, in part, through EET biosynthesis and is inhibited by biguanides
Journal Articles

Abstract 3270: Distinct and heterogeneous response of Ewing sarcoma cells to canonical Wnt signaling

Elisabeth Anne Pedersen, Rajasree Menon, Dafydd Thomas, Eric Fearon, Elizabeth Lawlor
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3270.
https://doi.org/10.1158/1538-7445.AM2015-3270
Published: 01 August 2015
View article titled, Abstract 3270: Distinct and heterogeneous response of Ewing sarcoma cells to canonical Wnt signaling
Journal Articles

Abstract 4065: Regulation of luminal breast cancer stem cells by HER2 does not require gene amplification providing a potential molecular explanation for the efficacy of adjuvant trastuzumab in patients with “clinically HER2-negative” breast cancer.

Korkaya Hasan, Fayaz Malik, Kathleen C. Day, Suthinee Ithimakin, April Davis, Ahmed A. Quraishi, Nader Tawakkol, Kathleen Woods Ignatoski, Dafydd Thomas, Shawn G. Clouthier, Max S. Wicha
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4065.
https://doi.org/10.1158/1538-7445.AM2013-4065
Published: 15 April 2013
View article titled, Abstract 4065: Regulation of luminal breast cancer stem cells by HER2 does not require gene amplification providing a potential molecular explanation for the efficacy of adjuvant trastuzumab in patients with “clinically HER2-negative” breast cancer.
Journal Articles

Abstract 5032: Elucidating the role of CXCR4 in Ewing sarcoma.

Melanie A. Krook, Lauren A. Nicholls, Natashay J. Bailey, Amy Han, Chris Scannell, Dafydd Thomas, Elizabeth R. Lawlor
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5032.
https://doi.org/10.1158/1538-7445.AM2013-5032
Published: 15 April 2013
View article titled, Abstract 5032: Elucidating the role of CXCR4 in Ewing sarcoma.
Journal Articles

Abstract 3470: HER2 drives luminal breast cancer stem cells in the absence of HER2 amplification: Implications for efficacy of adjuvant trastuzumab

Fayaz Malik, Suthinee Ithimakin, Kathleen Day, Kathy Ignatoski, Qin Zen, Dafydd Thomas, Tom Bersano, Scott Dawsey, Christopher Hall, April Davis, Ahmed A. Quraishi, Nader Tawakkol, Shawn G. Clouthier, Mark Day, Daniel F. Hayes, Hasan Korkaya, Max S. Wicha
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3470.
https://doi.org/10.1158/1538-7445.AM2012-3470
Published: 15 April 2012
View article titled, Abstract 3470: HER2 drives luminal breast cancer stem cells in the absence of HER2 amplification: Implications for efficacy of adjuvant trastuzumab
Journal Articles

Aldehyde Dehydrogenase in Combination with CD133 Defines Angiogenic Ovarian Cancer Stem Cells That Portend Poor Patient Survival

Ines A. Silva, Shoumei Bai, Karen McLean, Kun Yang, Kent Griffith, Dafydd Thomas, Christophe Ginestier, Carolyn Johnston, Angela Kueck, R. Kevin Reynolds, Max S. Wicha, Ronald J. Buckanovich
Journal: Cancer Research
Cancer Res (2011) 71 (11): 3991–4001.
https://doi.org/10.1158/0008-5472.CAN-10-3175
Published: 31 May 2011
View article titled, Aldehyde Dehydrogenase in Combination with CD133 Defines Angiogenic Ovarian Cancer Stem Cells That Portend Poor Patient Survival
Open the PDF for Aldehyde Dehydrogenase in Combination with CD133 Defines Angiogenic Ovarian Cancer Stem Cells That Portend Poor Patient Survival in another window
Includes: Supplementary data
Journal Articles

Abstract 357: CYP3A4 Activates Stat3 in ER + breast cancer

David A. Potter, Zhijun Guo, Ranjana Mitra, Monica Milani, Mariangellys Rodriguez, Li Ding, Robin Bliss, Julia Nguyen, Xianghua Luo, Kalpna Gupta, Jorge Capdevila, Ian Blair, Dafydd Thomas, Young K. Bae
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 357.
https://doi.org/10.1158/1538-7445.AM2011-357
Published: 15 April 2011
View article titled, Abstract 357: CYP3A4 Activates Stat3 in ER + breast cancer
Journal Articles

Growth Inhibition and Radiosensitization of Glioblastoma and Lung Cancer Cells by Small Interfering RNA Silencing of Tumor Necrosis Factor Receptor–Associated Factor 2

Min Zheng, Susan E. Morgan-Lappe, Jie Yang, Katrina M. Bockbrader, Deepika Pamarthy, Dafydd Thomas, Stephen W. Fesik, Yi Sun
Journal: Cancer Research
Cancer Res (2008) 68 (18): 7570–7578.
https://doi.org/10.1158/0008-5472.CAN-08-0632
Published: 14 September 2008
View article titled, Growth Inhibition and Radiosensitization of Glioblastoma and Lung Cancer Cells by Small Interfering RNA Silencing of Tumor Necrosis Factor Receptor–Associated Factor 2
Open the PDF for Growth Inhibition and Radiosensitization of Glioblastoma and Lung Cancer Cells by Small Interfering RNA Silencing of Tumor Necrosis Factor Receptor–Associated Factor 2 in another window
Journal Articles

CYP3A5 gene expression is associated with early recurrence of non-small cell lung cancer

Ranjana Mitra, Clementina Mesaros, Anjaiah Srirangam, Ahmed Mohiuddin, Todd Skaar, Beth Juliar, Lang Li, Sunil Badve, Oscar Cummings, Dafydd Thomas, Jeanette McClintick, Howard Edenberg, Ian Blair, David Potter
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5551.
Published: 01 May 2008
View article titled, CYP3A5 gene expression is associated with early recurrence of non-small cell lung cancer
Journal Articles

Selenium binding protein 1 expression is decreased during esophageal adenocarcinoma development and potentiates selenium-mediated cisplatinum chemosensitivity in vitro

Amy Silvers, Lin Lin, Guoan Chen, Zhuwen Wang, Dafydd Thomas, Thomas Giordano, David Beer, Andrew Chang
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2110.
Published: 01 May 2008
View article titled, Selenium binding protein 1 expression is decreased during esophageal adenocarcinoma development and potentiates selenium-mediated cisplatinum chemosensitivity <em>in vitro</em>