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Journal Articles

Abstract 4783: Selective antitumor activity of NSC311152 toward medullary thyroid cancer by downregulating the transcription of RET oncogene

Daekyu Sun, Vishnu Muthuraj Kumarasamy, Tariq Alqahtani

Cancer Res (2018) 78 (13_Supplement): 4783.

https://doi.org/10.1158/1538-7445.AM2018-4783

Published: 01 July 2018

View article titled, Abstract 4783: Selective antitumor activity of NSC311152 toward medullary thyroid cancer by downregulating the transcription of RET oncogene

Journal Articles

Abstract 5546: A natural alkaloid, berberine, as a novel transcriptional repressor of RET proto-oncogene in medullary thyroid carcinoma

Daekyu Sun, Vishnu Kumarasamy

Cancer Res (2015) 75 (15_Supplement): 5546.

https://doi.org/10.1158/1538-7445.AM2015-5546

Published: 01 August 2015

View article titled, Abstract 5546: A natural alkaloid, berberine, as a novel transcriptional repressor of RET proto-oncogene in medullary thyroid carcinoma

Journal Articles

Abstract 3208: Identification and characterization of a small molecule involved in the downregulation of RET transcription in MTC

Vishnu Muthuraj Kumarasamy, Yoon-Joo Shin, Daekyu Sun

Cancer Res (2014) 74 (19_Supplement): 3208.

https://doi.org/10.1158/1538-7445.AM2014-3208

Published: 01 October 2014

View article titled, Abstract 3208: Identification and characterization of a small molecule involved in the downregulation of RET transcription in MTC

Journal Articles

Abstract 745: Role of G-quadruplex structures in the human RET promoter region in the regulation of this gene.

Daekyu Sun, Yoon-Joo Shin

Cancer Res (2013) 73 (8_Supplement): 745.

https://doi.org/10.1158/1538-7445.AM2013-745

Published: 15 April 2013

View article titled, Abstract 745: Role of G-quadruplex structures in the human RET promoter region in the regulation of this gene.

Journal Articles

Abstract #5370: The i-motif structure in the GC-rich region upstream of the Bcl-2 P1 promoter and its putative role in the regulation of Bcl-2 transcription

Samantha Kendrick, Daekyu Sun, Laurence Hurley

Cancer Res (2009) 69 (9_Supplement): 5370.

Published: 01 May 2009

View article titled, Abstract #5370: The i-motif structure in the GC-rich region upstream of the Bcl-2 P1 promoter and its putative role in the regulation of Bcl-2 transcription

Journal Articles

Characterization of the C-rich secondary DNA structure in the SP1 binding region of the HIF1-alpha promoter

Diana Uribe, Vijay Gokhale, Scot Ebbinghaus, Laurence Hurley, Daekyu Sun

Cancer Res (2008) 68 (9_Supplement): 1762.

Published: 01 May 2008

View article titled, Characterization of the C-rich secondary DNA structure in the SP1 binding region of the HIF1-alpha promoter

Journal Articles

The cytosine-rich sequence within the Bcl-2 promoter region exhibits complex DNA secondary structure folding patterns.

Samantha Kendrick, Mary Gleason-Guzman, Daekyu Sun, Laurence Hurley

Cancer Res (2008) 68 (9_Supplement): 3191.

Published: 01 May 2008

View article titled, The cytosine-rich sequence within the Bcl-2 promoter region exhibits complex DNA secondary structure folding patterns.

Journal Articles

Differential binding of Nucleolin to G-quadruplex structures

Veronica Gonzalez-Pena, Daekyu Sun, Laurence Hurley

Cancer Res (2008) 68 (9_Supplement): 171.

Published: 01 May 2008

View article titled, Differential binding of Nucleolin to G-quadruplex structures

Journal Articles

DNA structural polymorphism in the proximal promoter of the vascular endothelial growth factor gene

Kexiao Guo, Vijay Gokhale, Laurence Hurley, Daekyu Sun

Cancer Res (2008) 68 (9_Supplement): 3189.

Published: 01 May 2008

View article titled, DNA structural polymorphism in the proximal promoter of the vascular endothelial growth factor gene

Journal Articles

Facilitation of a structural transition from a duplex to the i-motif and G-quadruplex structures within the nuclease hypersensitivity element of the c-MYC promoter by the presence of supercoiling stress and potassium.

Daekyu Sun, Mary Guzman, Laurence Hurley

Cancer Res (2008) 68 (9_Supplement): 90.

Published: 01 May 2008

View article titled, Facilitation of a structural transition from a duplex to the i-motif and G-quadruplex structures within the nuclease hypersensitivity element of the c-MYC promoter by the presence of supercoiling stress and potassium.

Journal Articles

Formation of G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene

Kexiao Guo, Alan Pourpak, Kara Beetz-Rogers, Laurence Hurley, Daekyu Sun

Cancer Res (2007) 67 (9_Supplement): 3175.

Published: 01 May 2007

View article titled, Formation of G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene

Journal Articles

Formation of the G-quadruplexes in the duplex DNA of PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4 in MIA Paca-2 cells

Yong Qin, Evonne Rezler, Vijay Gokhale, Daekyu Sun, Laurence Hurley

Cancer Res (2007) 67 (9_Supplement): 3164.

Published: 01 May 2007

View article titled, Formation of the G-quadruplexes in the duplex DNA of PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4 in MIA Paca-2 cells

Journal Articles

Molecular interactions of Nucleolin with the c-Myc G-quadruplex structure

Veronica Gonzalez-Pena, Daekyu Sun, Laurence Hurley

Cancer Res (2007) 67 (9_Supplement): LB-193.

Published: 01 May 2007

View article titled, Molecular interactions of Nucleolin with the c-Myc G-quadruplex structure

Journal Articles

Characterization of the i-motif structures formed by the C-rich strand of the proximal promoter region of the vascular endothelial growth factor gene

Daekyu Sun, Kexiao Guo, Jadrian Rusche, Laurence Hurley

Cancer Res (2007) 67 (9_Supplement): 1178.

Published: 01 May 2007

View article titled, Characterization of the i-motif structures formed by the C-rich strand of the proximal promoter region of the vascular endothelial growth factor gene

Journal Articles

In vitro footprinting of the promoter region of the human c-MYC proto-oncogene is consistent with the formation of i-motif and G-quadruplex structures in the coding and noncoding strands of the nuclease hypersensitivity element (NHE) III1 of the c-MYC promoter, respectively

Daekyu Sun, Jadrian Rusche, Laurence H. Hurley

Cancer Res (2006) 66 (8_Supplement): 211.

Published: 15 April 2006

View article titled, In vitro footprinting of the promoter region of the human c-MYC proto-oncogene is consistent with the formation of i-motif and G-quadruplex structures in the coding and noncoding strands of the nuclease hypersensitivity element (NHE) III1 of the c-MYC promoter, respectively

Journal Articles

Formation of G-quadruplexes in the PDGF-A promoter and mechanism for silencing by the 5` silencer element

Yong Qin, Evonne M. Rezler, Daekyu Sun, Laurence H. Hurley

Cancer Res (2005) 65 (9_Supplement): 1087.

Published: 01 May 2005

View article titled, Formation of G-quadruplexes in the PDGF-A promoter and mechanism for silencing by the 5` silencer element

Journal Articles

Characterization of the G-quadruplex structures formed by the G-rich strand of the proximal promoter region of the vascular endothelial growth factor gene

Daekyu Sun, Kexiao Guo, Jadrian J. Rusche, Laurence H. Hurley

Cancer Res (2005) 65 (9_Supplement): 882.

Published: 01 May 2005

View article titled, Characterization of the G-quadruplex structures formed by the G-rich strand of the proximal promoter region of the vascular endothelial growth factor gene

Journal Articles

In vitro and in vivo footprinting of the promoter region of the human vascular endothelial growth factor gene is consistent with G-quadruplex formation

Kexiao Guo, Daekyu Sun, Jadrian J. Rusche, Laurence H. Hurley

Cancer Res (2005) 65 (9_Supplement): 1439.

Published: 01 May 2005

View article titled, In vitro and in vivo footprinting of the promoter region of the human vascular endothelial growth factor gene is consistent with G-quadruplex formation

Journal Articles

The dynamic secondary DNA structures in the G- and C-rich strands of the NHE III1 in the c-Myc promoter

Tiffanie J. Bialis, Denise Tye, Jeyaprakashnarayanan Seenisamy, Evonne M. Rezler, Jack Griffith, Vijay Gokhale, Daekyu Sun, Laurence H. Hurley

Cancer Res (2005) 65 (9_Supplement): 1141.

Published: 01 May 2005

View article titled, The dynamic secondary DNA structures in the G- and C-rich strands of the NHE III1 in the c-Myc promoter

Journal Articles

Direct evidence for the formation G-quadruplex in the proximal promoter region of the VEGF gene and its targeting with a small molecule to repress VEGF gene transcription.

Daekyu Sun, Wei-Jun Liu, Laurence H. Hurley

Cancer Res (2004) 64 (7_Supplement): 837.

Published: 01 April 2004

View article titled, Direct evidence for the formation G-quadruplex in the proximal promoter region of the VEGF gene and its targeting with a small molecule to repress VEGF gene transcription.

NARROW

Abstract 4783: Selective antitumor activity of NSC311152 toward medullary thyroid cancer by downregulating the transcription of RET oncogene

Abstract 5546: A natural alkaloid, berberine, as a novel transcriptional repressor of RET proto-oncogene in medullary thyroid carcinoma

Abstract 3208: Identification and characterization of a small molecule involved in the downregulation of RET transcription in MTC

Abstract 745: Role of G-quadruplex structures in the human RET promoter region in the regulation of this gene.

Abstract #5370: The i-motif structure in the GC-rich region upstream of the Bcl-2 P1 promoter and its putative role in the regulation of Bcl-2 transcription

Characterization of the C-rich secondary DNA structure in the SP1 binding region of the HIF1-alpha promoter

The cytosine-rich sequence within the Bcl-2 promoter region exhibits complex DNA secondary structure folding patterns.

Differential binding of Nucleolin to G-quadruplex structures

DNA structural polymorphism in the proximal promoter of the vascular endothelial growth factor gene

Facilitation of a structural transition from a duplex to the i-motif and G-quadruplex structures within the nuclease hypersensitivity element of the c-MYC promoter by the presence of supercoiling stress and potassium.

Formation of G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene

Formation of the G-quadruplexes in the duplex DNA of PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4 in MIA Paca-2 cells

Molecular interactions of Nucleolin with the c-Myc G-quadruplex structure

Characterization of the i-motif structures formed by the C-rich strand of the proximal promoter region of the vascular endothelial growth factor gene

In vitro footprinting of the promoter region of the human c-MYC proto-oncogene is consistent with the formation of i-motif and G-quadruplex structures in the coding and noncoding strands of the nuclease hypersensitivity element (NHE) III1 of the c-MYC promoter, respectively

Formation of G-quadruplexes in the PDGF-A promoter and mechanism for silencing by the 5` silencer element

Characterization of the G-quadruplex structures formed by the G-rich strand of the proximal promoter region of the vascular endothelial growth factor gene

In vitro and in vivo footprinting of the promoter region of the human vascular endothelial growth factor gene is consistent with G-quadruplex formation

The dynamic secondary DNA structures in the G- and C-rich strands of the NHE III1 in the c-Myc promoter

Direct evidence for the formation G-quadruplex in the proximal promoter region of the VEGF gene and its targeting with a small molecule to repress VEGF gene transcription.

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