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D. Neil Watkins
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Journal Articles

MCAM Mediates Chemoresistance in Small-Cell Lung Cancer via the PI3K/AKT/SOX2 Signaling Pathway

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Satyendra C. Tripathi, Johannes F. Fahrmann, Muge Celiktas, Mitzi Aguilar, Kieren D. Marini, Mohit K. Jolly, Hiroyuki Katayama, Hong Wang, Eunice N. Murage, Jennifer B. Dennison, D. Neil Watkins, Herbert Levine, Edwin J. Ostrin, Ayumu Taguchi, Samir M. Hanash
Journal: Cancer Research
Cancer Res (2017) 77 (16): 4414–4425.
https://doi.org/10.1158/0008-5472.CAN-16-2874
Published: 14 August 2017
View article titled, MCAM Mediates Chemoresistance in Small-Cell Lung Cancer via the PI3K/AKT/SOX2 Signaling Pathway
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Includes: Supplementary data
Journal Articles

Abstract 3360: Targeted catalytic inhibition of EZH2 synergizes with low-dose HDACi in malignant rhabdoid tumors

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Dean Popovski, Elizabeth M. Algar, Catherine R. Cochrane, Anette Szczepny, W. Samantha Jayasekara, David M. Ashley, Peter Downie, D. Neil Watkins, Jason E. Cain
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3360.
https://doi.org/10.1158/1538-7445.AM2017-3360
Published: 01 July 2017
View article titled, Abstract 3360: Targeted catalytic inhibition of EZH2 synergizes with low-dose HDACi in malignant rhabdoid tumors
Journal Articles

Abstract 3170: MCAM modulates small cell lung cancer chemoresistance via PI3k/Akt/Sox2 signaling pathway

Free
Satyendra C. Tripathi, Johannes F. Fahrmann, Muge Celiktas, Mitzi Aguilar, Kieren D. Marini, Mohit K. Jolly, Hiroyuki Katayama, Hong Wang, Eunice N. Murage, Jennifer B. Dennison, D. Neil Watkins, Herbert Levine, Edwin J. Ostrin, Ayumu Taguchi, Samir M. Hanash
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3170.
https://doi.org/10.1158/1538-7445.AM2017-3170
Published: 01 July 2017
View article titled, Abstract 3170: MCAM modulates small cell lung cancer chemoresistance via PI3k/Akt/Sox2 signaling pathway
Journal Articles

Abstract 3318: Using synthetic lethal screening to identify therapeutic targets for innately platinum resistant lung cancer

Free
Kieren D. Marini, Fernando J. Rossello, Luciano G. Martelotto, D. Neil Watkins
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3318.
https://doi.org/10.1158/1538-7445.AM2014-3318
Published: 01 October 2014
View article titled, Abstract 3318: Using synthetic lethal screening to identify therapeutic targets for innately platinum resistant lung cancer
Journal Articles

Hedgehog Overexpression Is Associated with Stromal Interactions and Predicts for Poor Outcome in Breast Cancer

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Sandra A. O'Toole, Dorothy A. Machalek, Robert F. Shearer, Ewan K.A. Millar, Radhika Nair, Peter Schofield, Duncan McLeod, Caroline L. Cooper, Catriona M. McNeil, Andrea McFarland, Akira Nguyen, Christopher J. Ormandy, Min Ru Qiu, Brian Rabinovich, Luciano G. Martelotto, Duc Vu, Gregory E. Hannigan, Elizabeth A. Musgrove, Daniel Christ, Robert L. Sutherland, D. Neil Watkins, Alexander Swarbrick
Journal: Cancer Research
Cancer Res (2011) 71 (11): 4002–4014.
https://doi.org/10.1158/0008-5472.CAN-10-3738
Published: 31 May 2011
View article titled, Hedgehog Overexpression Is Associated with Stromal Interactions and Predicts for Poor Outcome in Breast Cancer
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Includes: Supplementary data
Journal Articles

Abstract #3831: Roles for Hic1 in tumor suppression and development through transcriptional repression of Ephrin A1

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Wei Zhang, Xiaobei Zeng, Kimberly Briggs, Ray-Whay Chiu Yen, Gregory Gesell, D Neil Watkins, Stephen Baylin
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3831.
Published: 01 May 2009
View article titled, Abstract #3831: Roles for Hic1 in tumor suppression and development through transcriptional repression of Ephrin A1
Journal Articles

Abstract #323: Induction of tumor-derived hedgehog ligand by chemotherapy

Free
Veronica Travaglione, Kerrie Faia, James Conley, Nita Frank, Jennifer Proctor, Kerry White, Marisa Osswalt, Igor Deyneko, John MacDougall, Craig Peacock, D Neil Watkins, Karen McGovern, Margaret Read
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 323.
Published: 01 May 2009
View article titled, Abstract #323: Induction of tumor-derived hedgehog ligand by chemotherapy
Journal Articles

A Primary Xenograft Model of Small-Cell Lung Cancer Reveals Irreversible Changes in Gene Expression Imposed by Culture In vitro

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Vincent C. Daniel, Luigi Marchionni, Jared S. Hierman, Jonathan T. Rhodes, Wendy L. Devereux, Charles M. Rudin, Rex Yung, Giovanni Parmigiani, Marion Dorsch, Craig D. Peacock, D. Neil Watkins
Journal: Cancer Research
Cancer Res (2009) 69 (8): 3364–3373.
https://doi.org/10.1158/0008-5472.CAN-08-4210
Published: 15 April 2009
View article titled, A Primary Xenograft Model of Small-Cell Lung Cancer Reveals Irreversible Changes in Gene Expression Imposed by Culture In vitro
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Includes: Supplementary data
Journal Articles

Just Say No to ATOH: How HIC1 Methylation Might Predispose Medulloblastoma to Lineage Addiction

Free
Kimberly J. Briggs, Charles G. Eberhart, D. Neil Watkins
Journal: Cancer Research
Cancer Res (2008) 68 (21): 8654–8656.
https://doi.org/10.1158/0008-5472.CAN-08-1904
Published: 30 October 2008
View article titled, Just Say No to ATOH: How HIC1 Methylation Might Predispose Medulloblastoma to Lineage Addiction
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Journal Articles

A novel HH pathway inhibitor, IPI-926, delays recurrence post-chemotherapy in a primary human SCLC xenograft model

Free
Veronica Travaglione, Craig Peacock, John MacDougall, Karen McGovern, Jill Cushing, Lin Chen Yu, Martin Trudeau, Vito Palombella, Julian Adams, Jared Hierman, Jonathon Rhodes, Wendy Devereux, D Neil Watkins
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4611.
Published: 01 May 2008
View article titled, A novel HH pathway inhibitor, IPI-926, delays recurrence post-chemotherapy in a primary human SCLC xenograft model
Journal Articles

Epigenetic Inactivation of the Canonical Wnt Antagonist SRY-Box Containing Gene 17 in Colorectal Cancer

Free
Wei Zhang, Sabine C. Glöckner, Mingzhou Guo, Emi Ota Machida, David H. Wang, Hariharan Easwaran, Leander Van Neste, James G. Herman, Kornel E. Schuebel, D. Neil Watkins, Nita Ahuja, Stephen B. Baylin
Journal: Cancer Research
Cancer Res (2008) 68 (8): 2764–2772.
https://doi.org/10.1158/0008-5472.CAN-07-6349
Published: 15 April 2008
View article titled, Epigenetic Inactivation of the Canonical Wnt Antagonist SRY-Box Containing Gene 17 in Colorectal Cancer
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Journal Articles

Therapeutic Efficacy of ABT-737, a Selective Inhibitor of BCL-2, in Small Cell Lung Cancer

Free
Christine L. Hann, Vincent C. Daniel, Elizabeth A. Sugar, Irina Dobromilskaya, Sara C. Murphy, Leslie Cope, Xue Lin, Jared S. Hierman, Daniel L. Wilburn, D. Neil Watkins, Charles M. Rudin
Journal: Cancer Research
Cancer Res (2008) 68 (7): 2321–2328.
https://doi.org/10.1158/0008-5472.CAN-07-5031
Published: 01 April 2008
View article titled, Therapeutic Efficacy of ABT-737, a Selective Inhibitor of BCL-2, in Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Clonogenic Multiple Myeloma Progenitors, Stem Cell Properties, and Drug Resistance

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William Matsui, Qiuju Wang, James P. Barber, Sarah Brennan, B. Douglas Smith, Ivan Borrello, Ian McNiece, Lan Lin, Richard F. Ambinder, Craig Peacock, D. Neil Watkins, Carol Ann Huff, Richard J. Jones
Journal: Cancer Research
Cancer Res (2008) 68 (1): 190–197.
https://doi.org/10.1158/0008-5472.CAN-07-3096
Published: 02 January 2008
View article titled, Clonogenic Multiple Myeloma Progenitors, Stem Cell Properties, and Drug Resistance
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Journal Articles

The tumor suppressor genes Hic1 and Ptch1 interact in the development of medulloblastoma

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Kimberly J. Briggs, Ian M. Corcoran-Schwartz, Thomas Harcke, Craig D. Peacock, Stephen B. Baylin, Charles G. Eberhart, D. Neil Watkins
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 598.
Published: 15 April 2006
View article titled, The tumor suppressor genes Hic1 and Ptch1 interact in the development of medulloblastoma
Journal Articles

Cell Surface Tumor Endothelial Markers Are Conserved in Mice and Humans

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Eleanor B. Carson-Walter, D. Neil Watkins, Akash Nanda, Bert Vogelstein, Kenneth W. Kinzler, Brad St. Croix
Journal: Cancer Research
Cancer Res (2001) 61 (18): 6649–6655.
Published: 01 September 2001
View article titled, Cell Surface Tumor Endothelial Markers Are Conserved in Mice and Humans
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Journal Articles

p14ARF Silencing by Promoter Hypermethylation Mediates Abnormal Intracellular Localization of MDM2

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Manel Esteller, Carlos Cordon-Cardo, Paul G. Corn, Steve J. Meltzer, Kamal S. Pohar, D. Neil Watkins, Gabriel Capella, Miguel Angel Peinado, Xavier Matias-Guiu, Jaime Prat, Stephen B. Baylin, James G. Herman
Journal: Cancer Research
Cancer Res (2001) 61 (7): 2816–2821.
Published: 01 April 2001
View article titled, p14ARF Silencing by Promoter Hypermethylation Mediates Abnormal Intracellular Localization of MDM2
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Journal Articles

Inactivation of the DNA Repair Gene O6-Methylguanine-DNA Methyltransferase by Promoter Hypermethylation Is Associated with G to A Mutations in K-ras in Colorectal Tumorigenesis

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Manel Esteller, Minoru Toyota, Montserrat Sanchez-Cespedes, Gabriel Capella, Miguel Angel Peinado, D. Neil Watkins, Jean-Pierre J. Issa, David Sidransky, Stephen B. Baylin, James G. Herman
Journal: Cancer Research
Cancer Res (2000) 60 (9): 2368–2371.
Published: 01 May 2000
View article titled, Inactivation of the DNA Repair Gene O6-Methylguanine-DNA Methyltransferase by Promoter Hypermethylation Is Associated with G to A Mutations in K-ras in Colorectal Tumorigenesis
Open the PDF for Inactivation of the DNA Repair Gene O6-Methylguanine-DNA Methyltransferase by Promoter Hypermethylation Is Associated with G to A Mutations in K-ras in Colorectal Tumorigenesis in another window